scPDB - Distribution of Binding site Similarity values of 3s7a entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3s7a	684	Dihydrofolate reductase	1.5.1.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
3s7a	684	Dihydrofolate reductase	1.5.1.3	1.000
1s3v	TQD	Dihydrofolate reductase	1.5.1.3	0.527
1pd9	CO4	Dihydrofolate reductase	1.5.1.3	0.520
1s3u	TQD	Dihydrofolate reductase	1.5.1.3	0.496
1mvs	DTM	Dihydrofolate reductase	1.5.1.3	0.491
1drf	FOL	Dihydrofolate reductase	1.5.1.3	0.488
2dhf	DZF	Dihydrofolate reductase	1.5.1.3	0.480
1mvt	DTM	Dihydrofolate reductase	1.5.1.3	0.455
3oaf	OAG	Dihydrofolate reductase	1.5.1.3	0.451
1dhf	FOL	Dihydrofolate reductase	1.5.1.3	0.445
3n0h	TOP	Dihydrofolate reductase	1.5.1.3	0.445