Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.11.000
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.613
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.604
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.603
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.586
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.579
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.578
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.578
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.574
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.571
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.570
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.570
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.569
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.569
3zh8C58Protein kinase C iota type2.7.11.130.566
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.566
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.562
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.562
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.560
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.559
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.557
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.555
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.550
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.550
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.547
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.543
2hog710Serine/threonine-protein kinase Chk12.7.11.10.542
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.542
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.541
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.541
3otuBI43-phosphoinositide-dependent protein kinase 12.7.11.10.540
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.540
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.539
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.537
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.534
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.534
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.528
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.528
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.527
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.527
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.526
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.525
4jia1K3Tyrosine-protein kinase JAK2/0.525
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.524
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.524
1bygSTUTyrosine-protein kinase CSK/0.523
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.523
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.522
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.519
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.518
2j0lANPFocal adhesion kinase 12.7.10.20.516
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.515
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.514
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.513
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.513
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.512
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.511
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.508
3ggfGVDSerine/threonine-protein kinase 26/0.508
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.507
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.507
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.506
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.506
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.506
3a7hATPSerine/threonine-protein kinase 242.7.11.10.506
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.504
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.504
4wq5ATPtRNA N6-adenosine threonylcarbamoyltransferase/0.504
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.503
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.502
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.501
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.500
2vd5BI8Myotonin-protein kinase2.7.11.10.500
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.500
1ig1ANPDeath-associated protein kinase 12.7.11.10.499
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.499
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.498
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.498
4ysjADPCalmodulin-like domain protein kinase/0.498
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.497
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.496
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.496
4gmy0X5Tyrosine-protein kinase JAK2/0.496
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.495
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.495
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.495
3t8oATPRhodopsin kinase/0.495
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.495
3qyw6PBMitogen-activated protein kinase 12.7.11.240.494
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.494
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.494
3rni21ZCyclin-dependent kinase 22.7.11.220.493
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.492
1xl2189Gag-Pol polyprotein3.4.23.160.491
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.490
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.490
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.490
4j98ACPFibroblast growth factor receptor 2/0.490
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.489
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.489
5av2KMPDeath-associated protein kinase 12.7.11.10.488
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.487
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.487
4erwSTUCyclin-dependent kinase 22.7.11.220.487
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.486
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.486
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.486
2pwlACPFibroblast growth factor receptor 2/0.485
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.485
1aq1STUCyclin-dependent kinase 22.7.11.220.484
1zrzBI1Protein kinase C iota type2.7.11.130.484
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.484
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.484
4fob0USALK tyrosine kinase receptor2.7.10.10.483
1jklANPDeath-associated protein kinase 12.7.11.10.482
4qmlANPSerine/threonine-protein kinase 242.7.11.10.482
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.481
2x1nX1NCyclin-dependent kinase 22.7.11.220.481
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.481
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.481
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.481
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.481
4fv6E57Mitogen-activated protein kinase 12.7.11.240.481
2ckeIQUDeath-associated protein kinase 2/0.480
3w551FMMitogen-activated protein kinase 12.7.11.240.480
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.480
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.480
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.480
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.479
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.479
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.478
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.478
3zep1NXTyrosine-protein kinase JAK32.7.10.20.478
5e8ySTUTGF-beta receptor type-22.7.11.300.478
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.477
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.477
1h1s4SPCyclin-dependent kinase 22.7.11.220.476
2ijmATPFocal adhesion kinase 12.7.10.20.476
3at4CCKCasein kinase II subunit alpha2.7.11.10.476
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.476
4h3qANPMitogen-activated protein kinase 12.7.11.240.476
2uzbC75Cyclin-dependent kinase 22.7.11.220.475
1k6cMK1Gag-Pol polyprotein3.4.23.160.474
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.474
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.474
2p33J07Mitogen-activated protein kinase 102.7.11.240.474
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.474
3gubGUBDeath-associated protein kinase 12.7.11.10.474
3zlx5EZDual specificity mitogen-activated protein kinase kinase 12.7.12.20.474
4y95746Tyrosine-protein kinase/0.474
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.473
2etm7PYFocal adhesion kinase 12.7.10.20.473
3a62STURibosomal protein S6 kinase beta-12.7.11.10.473
3pxkPXKFocal adhesion kinase 12.7.10.20.473
4e730NRMitogen-activated protein kinase 82.7.11.240.473
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.473
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.473
1pjkANPCasein kinase II subunit alpha2.7.11.10.472
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.472
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.472
3bqr4RBDeath-associated protein kinase 3/0.472
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.472
3cgfJNFMitogen-activated protein kinase 102.7.11.240.472
3eljGS7Mitogen-activated protein kinase 82.7.11.240.472
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.472
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.472
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.472
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.472
5auvAGIDeath-associated protein kinase 12.7.11.10.472
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.471
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.471
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
3igoANPCalmodulin-domain protein kinase 1, putative/0.471
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.471
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.471
4d4sBI9Focal adhesion kinase 12.7.10.20.471
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.471
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.471
4j95ACPFibroblast growth factor receptor 2/0.471
5ap7SVEDual specificity protein kinase TTK2.7.12.10.471
2j0m4STFocal adhesion kinase 12.7.10.20.470
2vu3LZECyclin-dependent kinase 22.7.11.220.470
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.470
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
4aqc88ATyrosine-protein kinase JAK2/0.470
4bcmT7ZCyclin-dependent kinase 22.7.11.220.470
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.469
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.469
3nwxKVSGag-Pol polyprotein3.4.23.160.469
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.469
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.469
3bheBZNGag-Pol polyprotein3.4.23.160.468
3lfqA28Cyclin-dependent kinase 22.7.11.220.468
3q9xEMOCasein kinase II subunit alpha2.7.11.10.468
3t2kFADSulfide-quinone reductase/0.468
4gu610NFocal adhesion kinase 12.7.10.20.468
5auwQUEDeath-associated protein kinase 12.7.11.10.468
1owmFADDeoxyribodipyrimidine photo-lyase4.1.99.30.467
1zaoATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.467
2bfyH1NAurora kinase B-A2.7.11.10.467
2in6839Wee1-like protein kinase2.7.10.20.467
2vgoAD5Aurora kinase B-A2.7.11.10.467
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.467
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.467
1xjdSTUProtein kinase C theta type2.7.11.130.466
2jkqVG8Focal adhesion kinase 12.7.10.20.466
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.466
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.466
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.466
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.466
4fv9E71Mitogen-activated protein kinase 12.7.11.240.466
4hge15VTyrosine-protein kinase JAK2/0.466
4hgs15GCasein kinase I isoform gamma-32.7.11.10.466
1bwsNDPGDP-L-fucose synthase/0.465
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.465
1u3cFADCryptochrome-1/0.465
2izuP01Casein kinase I isoform gamma-32.7.11.10.465
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.465
3oibFDAPutative acyl-CoA dehydrogenase/0.465
3w33W19Epidermal growth factor receptor2.7.10.10.465
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.465
1k6pXN3Gag-Pol polyprotein3.4.23.160.464
1oirHDYCyclin-dependent kinase 22.7.11.220.464
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.464
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.464
2hc4VDXVitamin D3 receptor A/0.464
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.464
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.464
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.464
4j97ACPFibroblast growth factor receptor 2/0.464
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.464
1nzdUPGDNA beta-glucosyltransferase/0.463
1oitHDTCyclin-dependent kinase 22.7.11.220.463
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.463
3iok1P6Tyrosine-protein kinase JAK2/0.463
3ormAGSSerine/threonine protein kinase/0.463
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.463
4ix6ADPUncharacterized protein/0.463
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.462
3gu6ADPDeath-associated protein kinase 12.7.11.10.462
3lfsA07Cyclin-dependent kinase 22.7.11.220.462
3zptM8YGag-Pol polyprotein3.4.23.160.462
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.462
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.462
4gk4L90Ephrin type-A receptor 32.7.10.10.462
4jqeANPCasein kinase II subunit alpha2.7.11.10.462
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.462
4xj3GTPCyclic GMP-AMP synthase/0.462
3gu83GUDeath-associated protein kinase 12.7.11.10.461
3nynSGVG protein-coupled receptor kinase 62.7.11.160.461
4b8lA0PAurora kinase B-A2.7.11.10.461
4grb0XGCasein kinase II subunit alpha2.7.11.10.461
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.461
5av3KMPDeath-associated protein kinase 12.7.11.10.461
3sn6P0GBeta-2 adrenergic receptor/0.461
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.460
2xb7GUIALK tyrosine kinase receptor2.7.10.10.460
2yaaATPDeath-associated protein kinase 2/0.460
3c4zADPRhodopsin kinase/0.460
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.460
3sheI85MAP kinase-activated protein kinase 32.7.11.10.460
4hvi19STyrosine-protein kinase JAK32.7.10.20.460
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.460
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.460
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.460
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.459
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.459
3lltANPProtein serine/threonine kinase-1/0.459
4ekl0RFRAC-alpha serine/threonine-protein kinase2.7.11.10.459
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.459
2i40BLZCyclin-dependent kinase 22.7.11.220.458
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.458
2yn8STUEphrin type-B receptor 42.7.10.10.458
4jq8KJ8Epidermal growth factor receptor2.7.10.10.458
4ks7X4ZSerine/threonine-protein kinase PAK 62.7.11.10.458
1ownFADDeoxyribodipyrimidine photo-lyase4.1.99.30.457
3dfcANPDeath-associated protein kinase 12.7.11.10.457
3oroAGSSerine/threonine protein kinase/0.457
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.457
4ez50RSCyclin-dependent kinase 62.7.11.220.457
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.457
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.457
4g3pUD1Bifunctional protein GlmU/0.457
4qmpDKISerine/threonine-protein kinase 242.7.11.10.457
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.457
1pmn984Mitogen-activated protein kinase 102.7.11.240.456
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
1ykfNAPNADP-dependent isopropanol dehydrogenase1.1.1.800.456
2w17I19Cyclin-dependent kinase 22.7.11.220.456
2zjwREFCasein kinase II subunit alpha2.7.11.10.456
3bhy7CPDeath-associated protein kinase 3/0.456
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
3uyt0CKCasein kinase I isoform delta2.7.11.10.456
3zewSTUEphrin type-B receptor 42.7.10.10.456
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.456
4g3qUD1Bifunctional protein GlmU/0.456
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
1oiyN41Cyclin-dependent kinase 22.7.11.220.455
1u3dFADCryptochrome-1/0.455
3gu7ADPDeath-associated protein kinase 12.7.11.10.455
3qzhX69Cyclin-dependent kinase 22.7.11.220.455
4fmqANPMitogen-activated protein kinase 12.7.11.240.455
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.455
4qnaX11Serine/threonine-protein kinase 242.7.11.10.455
1owpFADDeoxyribodipyrimidine photo-lyase4.1.99.30.454
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.454
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
2pwrG4GGag-Pol polyprotein3.4.23.160.454
2y9qANPMitogen-activated protein kinase 12.7.11.240.454
3bu5ATPInsulin receptor2.7.10.10.454
3gggNADPrephenate dehydrogenase/0.454
3q9wEMOCasein kinase II subunit alpha2.7.11.10.454
3t54ATPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.454
4acm7YGCyclin-dependent kinase 22.7.11.220.454
4d58BI9Focal adhesion kinase 12.7.10.20.454
4fhi0S4Vitamin D3 receptor A/0.454
4gyiADPUncharacterized protein/0.454
4ic7ANPMitogen-activated protein kinase 72.7.11.240.454
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.454
1qmzATPCyclin-dependent kinase 22.7.11.220.453
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
1wvySTUDeath-associated protein kinase 12.7.11.10.453
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
2a0cCK9Cyclin-dependent kinase 22.7.11.220.453
2xrwANPMitogen-activated protein kinase 82.7.11.240.453
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.453
3eyhIZATyrosine-protein kinase JAK1/0.453
3vt45YIVitamin D3 receptor/0.453
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4fkv61KCyclin-dependent kinase 22.7.11.220.453
4hjoAQ4Epidermal growth factor receptor2.7.10.10.453
4qmzB49Serine/threonine-protein kinase 242.7.11.10.453
1k6tXN1Gag-Pol polyprotein3.4.23.160.452
2b7aIZATyrosine-protein kinase JAK2/0.452
2hamC33Vitamin D3 receptor/0.452
2ijmADPFocal adhesion kinase 12.7.10.20.452
2j0k4STFocal adhesion kinase 12.7.10.20.452
2pywADPMethylthioribose kinase2.7.1.1000.452
2qo9ANPEphrin type-A receptor 32.7.10.10.452
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.452
3c4xATPRhodopsin kinase/0.452
3ezrEZRCyclin-dependent kinase 22.7.11.220.452
3lpbNVBTyrosine-protein kinase JAK2/0.452
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.452
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4fv8E63Mitogen-activated protein kinase 12.7.11.240.452
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
5cvfATPCasein kinase II subunit alpha2.7.11.10.452
5itzLOCTubulin beta-2B chain/0.452
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
1m17AQ4Epidermal growth factor receptor2.7.10.10.451
1owoFADDeoxyribodipyrimidine photo-lyase4.1.99.30.451
1tvoFRZMitogen-activated protein kinase 12.7.11.240.451
1u4dDBQActivated CDC42 kinase 1/0.451
2a4lRRCCyclin-dependent kinase 22.7.11.220.451
2izt23DCasein kinase I isoform gamma-32.7.11.10.451
2vtqLZACyclin-dependent kinase 22.7.11.220.451
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.451
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.451
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.451
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.451
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.451
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.451
3rvg17PTyrosine-protein kinase JAK2/0.451
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.451
4dgnLU2Casein kinase II subunit alpha2.7.11.10.451
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.451
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.451
4gu94GUFocal adhesion kinase 12.7.10.20.451
4ivb1J5Tyrosine-protein kinase JAK1/0.451
1iqrFADDeoxyribodipyrimidine photo-lyase4.1.99.30.450
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.450
1yvj4STTyrosine-protein kinase JAK32.7.10.20.450
2itnANPEpidermal growth factor receptor2.7.10.10.450
2iw84SPCyclin-dependent kinase 22.7.11.220.450
2j3iNAPNADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.450
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.450
2xvdAS6Ephrin type-B receptor 42.7.10.10.450
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.450
3axwTIDCasein kinase II subunit alpha2.7.11.10.450
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.450
3inmNDPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.450
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.450
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.450
3qqlX03Cyclin-dependent kinase 22.7.11.220.450
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.450
5c03AGSNon-receptor tyrosine-protein kinase TYK22.7.10.20.450
1kzjCB3Thymidylate synthase/0.449
1pkdUCNCyclin-dependent kinase 22.7.11.220.449
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.449
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.449
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.449
3q4zANPSerine/threonine-protein kinase PAK 12.7.11.10.449
3t2zFADSulfide-quinone reductase/0.449
3w0c6DSVitamin D3 receptor/0.449
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.449
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.449
4fv2EK5Mitogen-activated protein kinase 12.7.11.240.449
4wq4ATPtRNA N6-adenosine threonylcarbamoyltransferase/0.449
4y93746Tyrosine-protein kinase/0.449
1eh4IC1Casein kinase I homolog 12.7.11.10.448
1g5sI17Cyclin-dependent kinase 22.7.11.220.448
1sn5T3Transthyretin/0.448
1xkkFMMEpidermal growth factor receptor2.7.10.10.448
2c5yMTWCyclin-dependent kinase 22.7.11.220.448
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.448
2g5cNADPrephenate dehydrogenase/0.448
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.448
2z7qACPRibosomal protein S6 kinase alpha-12.7.11.10.447
3tnwF18Cyclin-dependent kinase 22.7.11.220.447
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.447
4c4f7CEDual specificity protein kinase TTK2.7.12.10.447
4ix5ANPUncharacterized protein/0.447
4j6i1JVPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4j99ACPFibroblast growth factor receptor 2/0.447
4nifANPMitogen-activated protein kinase 12.7.11.240.447
4y12AGSSerine/threonine-protein kinase PknG2.7.11.10.447
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.446
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.446
2vn9GVDCalcium/calmodulin-dependent protein kinase type II subunit delta2.7.11.170.446
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.446
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.446
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.446
3kvxFMYMitogen-activated protein kinase 102.7.11.240.446
3rm618ZCyclin-dependent kinase 22.7.11.220.446
3vruYS3Vitamin D3 receptor/0.446
4a9mP9MBromodomain-containing protein 2/0.446
4fod0UVALK tyrosine kinase receptor2.7.10.10.446
4h3f10OBeta-secretase 13.4.23.460.446
4ji91M3Tyrosine-protein kinase JAK2/0.446
5cshATPCasein kinase II subunit alpha2.7.11.10.446
5cvhADPCasein kinase II subunit alpha2.7.11.10.446
1eupASD6-deoxyerythronolide B hydroxylase/0.445
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.445
2xa4AZ5Tyrosine-protein kinase JAK2/0.445
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.445
3etgNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.445
3kpkFADSulfide-quinone reductase/0.445
3w32W32Epidermal growth factor receptor2.7.10.10.445
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.445
4hyu1BKMitogen-activated protein kinase 82.7.11.240.445
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.445
4l9i8PRRhodopsin kinase/0.445
1tezFADDeoxyribodipyrimidine photo-lyase4.1.99.30.444
1u54ACPActivated CDC42 kinase 1/0.444
1wvxBD4Death-associated protein kinase 12.7.11.10.444
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.444
2v7a627Tyrosine-protein kinase ABL12.7.10.20.444
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.444
4req5ADMethylmalonyl-CoA mutase large subunit5.4.99.20.444
4xlvACPInsulin receptor2.7.10.10.444
5l8lADPAurora kinase A2.7.11.10.444
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.443
1e9hINRCyclin-dependent kinase 22.7.11.220.443
1mqbANPEphrin type-A receptor 22.7.10.10.443
1t0lNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.443
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.443
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.443
2ojj82AMitogen-activated protein kinase 12.7.11.240.443
2x3nFADProbable FAD-dependent monooxygenase/0.443
3a783EVVitamin D3 receptor/0.443
3d8vUD1Bifunctional protein GlmU/0.443
3l0lHC3Nuclear receptor ROR-gamma/0.443
4aguD15Cyclin-dependent kinase-like 1/0.443
4btjATPTau-tubulin kinase 12.7.11.10.443
4gfg0XFTyrosine-protein kinase SYK2.7.10.20.443
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.443
4ruoBIVVitamin D3 receptor A/0.443
1gqtACPRibokinase/0.442
1jioDEB6-deoxyerythronolide B hydroxylase/0.442
1jkkANPDeath-associated protein kinase 12.7.11.10.442
1txiTX5Vitamin D3 receptor/0.442
2hcdBIVVitamin D3 receptor A/0.442
2olcADPMethylthioribose kinase2.7.1.1000.442
2w4jADPDeath-associated protein kinase 12.7.11.10.442
3bgcLJHGag-Pol polyprotein3.4.23.160.442
3p4tFAOPutative acyl-CoA dehydrogenase/0.442
4cd0AWJALK tyrosine kinase receptor2.7.10.10.442
4eomATPCyclin-dependent kinase 22.7.11.220.442
4foc0UUALK tyrosine kinase receptor2.7.10.10.442
4iteTEYVitamin D3 receptor/0.442
4iwd1JCHepatocyte growth factor receptor2.7.10.10.442
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.442
2c6hPXICytochrome P450 monooxygenase PikC/0.441
2cmvNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.441
2j0j4STFocal adhesion kinase 12.7.10.20.441
2j4z626Aurora kinase A2.7.11.10.441
2oapANPType II secretion system protein (GspE-2)/0.441
2pmlANPUncharacterized protein/0.441
2pwcG3GGag-Pol polyprotein3.4.23.160.441
2pym1UNGag-Pol polyprotein3.4.23.160.441
2uy0HV1Gag-Pol polyprotein3.4.23.160.441
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.441
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.441
3fzpAGSProtein-tyrosine kinase 2-beta2.7.10.20.441
3plsANPMacrophage-stimulating protein receptor2.7.10.10.441
3qlrNDPDihydrofolate reductase1.5.1.30.441
3r9nZ68Cyclin-dependent kinase 22.7.11.220.441
3s1h56ZCyclin-dependent kinase 22.7.11.220.441
3w8qAGSDual specificity mitogen-activated protein kinase kinase 12.7.12.20.441
4fkw62KCyclin-dependent kinase 22.7.11.220.441
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.441
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.440
1ie4T44Transthyretin/0.440
1q99ANPSerine/threonine-protein kinase SKY12.7.11.10.440
2bujSTUSerine/threonine-protein kinase 16/0.440
2harOCCVitamin D3 receptor/0.440
2uw4L15cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
2uzdC85Cyclin-dependent kinase 22.7.11.220.440
2w05FRTCyclin-dependent kinase 22.7.11.220.440
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.440
3gobHXXDdmC/0.440
3my5RFZCyclin-dependent kinase 22.7.11.220.440
3s2pPMUCyclin-dependent kinase 22.7.11.220.440
3tm0ANPAminoglycoside 3'-phosphotransferase2.7.1.950.440
3u4uLNHCasein kinase II subunit alpha2.7.11.10.440
4btjADPTau-tubulin kinase 12.7.11.10.440
4i22IREEpidermal growth factor receptor2.7.10.10.440
4nk92K5Fibroblast growth factor receptor 1/0.440
4o0wADNAurora kinase A2.7.11.10.440
4q71FADBifunctional protein PutA/0.440
5eg3ACPFibroblast growth factor receptor 2/0.440