sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3rt8 | CWD | Glutamate receptor 3 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3rt8 | CWD | Glutamate receptor 3 | / | 1.000 | |
| 3tza | TZG | Glutamate receptor 2 | / | 0.574 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.522 | |
| 3b7d | CNI | Glutamate receptor 2 | / | 0.518 | |
| 4f1y | CNI | Glutamate receptor 3 | / | 0.503 | |
| 1ftl | DNQ | Glutamate receptor 2 | / | 0.500 | |
| 1lb9 | DNQ | Glutamate receptor 2 | / | 0.495 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.484 | |
| 2wky | IBC | Glutamate receptor ionotropic, kainate 1 | / | 0.476 | |
| 3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.476 | |
| 3h03 | UBP | Glutamate receptor 2 | / | 0.475 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.473 | |
| 2qs1 | UB1 | Glutamate receptor ionotropic, kainate 1 | / | 0.472 | |
| 4l17 | DNQ | Glutamate receptor 2 | / | 0.472 | |
| 3s2v | 3HU | Glutamate receptor ionotropic, kainate 1 | / | 0.470 | |
| 2y88 | 2ER | Phosphoribosyl isomerase A | 5.3.1.16 | 0.465 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.461 | |
| 4y3z | F41 | Endothiapepsin | 3.4.23.22 | 0.454 | |
| 1knr | FAD | L-aspartate oxidase | 1.4.3.16 | 0.453 | |
| 1vso | AT1 | Glutamate receptor ionotropic, kainate 1 | / | 0.452 | |
| 3c34 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.452 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.451 | |
| 4jld | ADP | Adenylate kinase | / | 0.451 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.450 | |
| 4dld | TZG | Glutamate receptor ionotropic, kainate 1 | / | 0.446 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.445 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.445 | |
| 3e9s | TTT | Replicase polyprotein 1ab | 3.4.22 | 0.445 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.444 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.444 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.442 | |
| 2ejz | SAH | Diphthine synthase | / | 0.442 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.442 | |
| 4jzr | 4JR | Egl nine homolog 1 | / | 0.442 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.442 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.442 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.441 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 1g8o | U5P | N-acetyllactosaminide alpha-1,3-galactosyltransferase | / | 0.440 |