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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3rr3FLRProstaglandin G/H synthase 21.14.99.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3rr3FLRProstaglandin G/H synthase 21.14.99.11.000
4coxIMNProstaglandin G/H synthase 21.14.99.10.634
4fm5DF0Prostaglandin G/H synthase 21.14.99.10.630
3ntgD72Prostaglandin G/H synthase 21.14.99.10.618
3mqe416Prostaglandin G/H synthase 21.14.99.10.602
3ln1CELProstaglandin G/H synthase 21.14.99.10.570
6coxS58Prostaglandin G/H synthase 21.14.99.10.569
3q7dNPXProstaglandin G/H synthase 21.14.99.10.568
5ikqJMSProstaglandin G/H synthase 21.14.99.10.555
4ph9IBPProstaglandin G/H synthase 21.14.99.10.546
3n8wFLPProstaglandin G/H synthase 11.14.99.10.543
2oyeIM8Prostaglandin G/H synthase 11.14.99.10.542
5ikrID8Prostaglandin G/H synthase 21.14.99.10.539
4otyLURProstaglandin G/H synthase 21.14.99.10.527
1eqhFLPProstaglandin G/H synthase 11.14.99.10.523
3n8xNIMProstaglandin G/H synthase 11.14.99.10.523
2oyuIMSProstaglandin G/H synthase 11.14.99.10.522
2aylFLPProstaglandin G/H synthase 11.14.99.10.517
1ht834CProstaglandin G/H synthase 11.14.99.10.516
4rrxLURProstaglandin G/H synthase 21.14.99.10.516
3pghFLPProstaglandin G/H synthase 21.14.99.10.512
3kk6CELProstaglandin G/H synthase 11.14.99.10.508
1eqgIBPProstaglandin G/H synthase 11.14.99.10.505
4rrwLURProstaglandin G/H synthase 21.14.99.10.505
4rrzLURProstaglandin G/H synthase 21.14.99.10.505
1q4gBFLProstaglandin G/H synthase 11.14.99.10.498
3n8zFLPProstaglandin G/H synthase 11.14.99.10.498
1pxxDIFProstaglandin G/H synthase 21.14.99.10.472
1cx2S58Prostaglandin G/H synthase 21.14.99.10.463
4jqh1MFAlr2278 protein/0.458
3gw9VNILanosterol 14-alpha-demethylase/0.449
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
3n8yDIFProstaglandin G/H synthase 11.14.99.10.444
4m10ICDProstaglandin G/H synthase 21.14.99.10.444
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.442