Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3rps | 4B0 | Casein kinase II subunit alpha | 2.7.11.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3rps | 4B0 | Casein kinase II subunit alpha | 2.7.11.1 | 1.000 | |
| 5cvh | ADP | Casein kinase II subunit alpha | 2.7.11.1 | 0.554 | |
| 2pvl | P55 | Casein kinase II subunit alpha | 2.7.11.1 | 0.533 | |
| 3q9w | EMO | Casein kinase II subunit alpha | 2.7.11.1 | 0.532 | |
| 4mwh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.532 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.524 | |
| 4fi1 | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.519 | |
| 1lp4 | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.518 | |
| 3q9x | EMO | Casein kinase II subunit alpha | 2.7.11.1 | 0.514 | |
| 2pvh | P19 | Casein kinase II subunit alpha | 2.7.11.1 | 0.512 | |
| 3rk7 | 08Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.506 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.503 | |
| 3nsz | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.503 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.502 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.498 | |
| 4gfo | 0X2 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.498 | |
| 4jr7 | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.498 | |
| 3mfs | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.496 | |
| 5csh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.496 | |
| 2uzl | C94 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.495 | |
| 2vuw | 5ID | Serine/threonine-protein kinase haspin | 2.7.11.1 | 0.495 | |
| 3r73 | X87 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.495 | |
| 1y91 | CT9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.494 | |
| 4enx | Z20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.494 | |
| 3oro | AGS | Serine/threonine protein kinase | / | 0.493 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.492 | |
| 4dgn | LU2 | Casein kinase II subunit alpha | 2.7.11.1 | 0.492 | |
| 1m2r | MNY | Casein kinase II subunit alpha | 2.7.11.1 | 0.491 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.491 | |
| 4xlv | ACP | Insulin receptor | 2.7.10.1 | 0.491 | |
| 3ort | AGS | Serine/threonine protein kinase | / | 0.488 | |
| 4f7l | 0SO | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.487 | |
| 1day | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.486 | |
| 2c5y | MTW | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.486 | |
| 3orm | AGS | Serine/threonine protein kinase | / | 0.486 | |
| 2ds1 | 1CD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.485 | |
| 3ofm | 4B0 | Casein kinase II subunit alpha' | 2.7.11.1 | 0.485 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.483 | |
| 3niz | ADP | Cdc2-like CDK2/CDC28 like protein kinase | / | 0.483 | |
| 3rmf | 20Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.483 | |
| 3v5l | 0G1 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.483 | |
| 4foc | 0UU | ALK tyrosine kinase receptor | 2.7.10.1 | 0.481 | |
| 1daw | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.480 | |
| 1g5s | I17 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.479 | |
| 3igo | ANP | Calmodulin-domain protein kinase 1, putative | / | 0.479 | |
| 4ijp | 1EH | Serine/threonine-protein kinase PRP4 homolog | 2.7.11.1 | 0.479 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.478 | |
| 3r9o | Z71 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.478 | |
| 4lfi | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.478 | |
| 1ir3 | ANP | Insulin receptor | 2.7.10.1 | 0.477 | |
| 1m2p | HNA | Casein kinase II subunit alpha | 2.7.11.1 | 0.477 | |
| 1v0o | INR | Cell division control protein 2 homolog | 2.7.11.22 | 0.477 | |
| 4b7d | QLE | Cytochrome P450 monooxygenase PikC | / | 0.477 | |
| 3c13 | EMO | Casein kinase II subunit alpha | 2.7.11.1 | 0.476 | |
| 3le6 | 2BZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.476 | |
| 4l3j | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.476 | |
| 2obj | VRV | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.475 | |
| 4ix6 | ADP | Uncharacterized protein | / | 0.475 | |
| 4n57 | ADP | APH(2'')-Id | / | 0.475 | |
| 4nr4 | 2LK | CREB-binding protein | / | 0.475 | |
| 3q9z | TXQ | Casein kinase II subunit alpha | 2.7.11.1 | 0.474 | |
| 4eny | J19 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.474 | |
| 1csn | ATP | Casein kinase I homolog 1 | 2.7.11.1 | 0.473 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.473 | |
| 1xjd | STU | Protein kinase C theta type | 2.7.11.13 | 0.473 | |
| 3wow | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.473 | |
| 4eoo | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.473 | |
| 4erw | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.473 | |
| 4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.473 | |
| 3cgf | JNF | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.472 | |
| 3llt | ANP | Protein serine/threonine kinase-1 | / | 0.472 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.472 | |
| 4oac | ADP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.472 | |
| 2pdt | FAD | Vivid PAS protein VVD | / | 0.471 | |
| 2uzb | C75 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.471 | |
| 3cgo | JNO | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.471 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.471 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.471 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.470 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.470 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.470 | |
| 4hee | 14R | Peroxisome proliferator-activated receptor gamma | / | 0.470 | |
| 4ix5 | ANP | Uncharacterized protein | / | 0.470 | |
| 4k18 | 1OB | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.470 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.470 | |
| 1b38 | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.469 | |
| 1aq1 | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 1mru | AGS | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.468 | |
| 3ckx | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.468 | |
| 3dcv | 55E | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.468 | |
| 3lfq | A28 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 3rk9 | 09Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.468 | |
| 1m2q | MNX | Casein kinase II subunit alpha | 2.7.11.1 | 0.466 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.466 | |
| 4krc | AGS | Cyclin-dependent protein kinase PHO85 | 2.7.11.22 | 0.466 | |
| 5cu6 | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.466 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.465 | |
| 4dgo | 0JW | Casein kinase II subunit alpha | 2.7.11.1 | 0.465 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.465 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.465 | |
| 1xr1 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.464 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.464 | |
| 2izu | P01 | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.464 | |
| 2pvm | P29 | Casein kinase II subunit alpha | 2.7.11.1 | 0.464 | |
| 3gu6 | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.464 | |
| 3tku | M77 | Serine/threonine-protein kinase MRCK beta | 2.7.11.1 | 0.464 | |
| 4dgm | AGI | Casein kinase II subunit alpha | 2.7.11.1 | 0.464 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.464 | |
| 2vag | V25 | Dual specificity protein kinase CLK1 | 2.7.12.1 | 0.463 | |
| 3a7j | ADP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.463 | |
| 3fz1 | B98 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 3lq5 | SLQ | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.463 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.463 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.463 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.463 | |
| 2csn | CKI | Casein kinase I homolog 1 | 2.7.11.1 | 0.462 | |
| 2x7g | PVB | SRSF protein kinase 2 | 2.7.11.1 | 0.462 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.462 | |
| 3w0n | ANP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.462 | |
| 4deg | 0JJ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.462 | |
| 5auv | AGI | Death-associated protein kinase 1 | 2.7.11.1 | 0.462 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.462 | |
| 1h1q | 2A6 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 1mq4 | ADP | Aurora kinase A | 2.7.11.1 | 0.461 | |
| 1oiu | N76 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.461 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.461 | |
| 1yw2 | PGJ | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 2h12 | CMX | Citrate synthase | / | 0.461 | |
| 3bqc | EMO | Casein kinase II subunit alpha | 2.7.11.1 | 0.461 | |
| 3eej | 53R | Uncharacterized protein | / | 0.461 | |
| 4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.461 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.460 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.460 | |
| 3gu8 | 3GU | Death-associated protein kinase 1 | 2.7.11.1 | 0.460 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.460 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.460 | |
| 3zlx | 5EZ | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.460 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.460 | |
| 4eu5 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.460 | |
| 4ix4 | ADP | Uncharacterized protein | / | 0.460 | |
| 1v0p | PVB | Cell division control protein 2 homolog | 2.7.11.22 | 0.459 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.459 | |
| 2f2c | AP9 | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.459 | |
| 2pzi | AXX | Serine/threonine-protein kinase PknG | 2.7.11.1 | 0.459 | |
| 2uzd | C85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 2w17 | I19 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.459 | |
| 2xj1 | XJ1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.459 | |
| 3at3 | ATK | Casein kinase II subunit alpha | 2.7.11.1 | 0.459 | |
| 3kf7 | L9G | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 4ek8 | 16K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 4ii5 | ADP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 5av4 | GEN | Death-associated protein kinase 1 | 2.7.11.1 | 0.459 | |
| 1fvv | 107 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 1pxo | CK7 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 1q8y | ADP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.458 | |
| 2b9j | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.458 | |
| 2uzt | SS3 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.458 | |
| 3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.458 | |
| 3r71 | X86 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.458 | |
| 4cki | ADN | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.458 | |
| 4eon | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 5auw | QUE | Death-associated protein kinase 1 | 2.7.11.1 | 0.458 | |
| 1yvj | 4ST | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.457 | |
| 2xbj | XBJ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.457 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.457 | |
| 3dfc | ANP | Death-associated protein kinase 1 | 2.7.11.1 | 0.457 | |
| 3gbk | 2PQ | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 3rpo | 24Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 3rpv | 26Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 4fks | 46K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.457 | |
| 4zse | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.457 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.456 | |
| 1ig1 | ANP | Death-associated protein kinase 1 | 2.7.11.1 | 0.456 | |
| 1p4f | DRG | Death-associated protein kinase 1 | 2.7.11.1 | 0.456 | |
| 2c5n | CK8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 2cke | IQU | Death-associated protein kinase 2 | / | 0.456 | |
| 3bhh | 5CP | Calcium/calmodulin-dependent protein kinase type II subunit beta | 2.7.11.17 | 0.456 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.456 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.456 | |
| 3s2a | 2NQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 4ezj | 0SC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.456 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 4kik | KSA | Inhibitor of nuclear factor kappa-B kinase subunit beta | 2.7.11.10 | 0.456 | |
| 1hck | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 3qqh | X0A | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 3qx4 | X4B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.455 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.455 | |
| 4ez5 | 0RS | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.455 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 4hyu | 1BK | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.455 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.455 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 1om1 | IQA | Casein kinase II subunit alpha | 2.7.11.1 | 0.454 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.454 | |
| 3hmm | 855 | TGF-beta receptor type-1 | 2.7.11.30 | 0.454 | |
| 3qqk | X02 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.454 | |
| 4bch | T7Z | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.454 | |
| 4fkv | 61K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 4o0w | ADN | Aurora kinase A | 2.7.11.1 | 0.454 | |
| 5av2 | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.454 | |
| 2b52 | D42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 3d7t | STU | Tyrosine-protein kinase CSK | / | 0.453 | |
| 3kga | LX9 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.453 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.453 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.453 | |
| 3rkb | 12Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.453 | |
| 4mq1 | 2C3 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.453 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.453 | |
| 4rrf | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.453 | |
| 5dgz | L20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.453 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.452 | |
| 2a4l | RRC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3gxl | QIG | TGF-beta receptor type-1 | 2.7.11.30 | 0.452 | |
| 3qx2 | X63 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 4j95 | ACP | Fibroblast growth factor receptor 2 | / | 0.452 | |
| 1o6y | ACP | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.451 | |
| 1q4u | 4CA | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.451 | |
| 2duv | 371 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2exc | JNK | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.451 | |
| 2ghm | LIC | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 2vv9 | IM9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 3lam | KRP | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 3umx | Q18 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.451 | |
| 4dee | ADP | Aurora kinase A | 2.7.11.1 | 0.451 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.451 | |
| 4i2q | 1BT | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 4i3z | ADP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 4lv7 | ADP | Inositol-pentakisphosphate 2-kinase | 2.7.1.158 | 0.451 | |
| 4q5j | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.451 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.450 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 3q4z | ANP | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.450 | |
| 3rak | 03Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3rm6 | 18Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3uzp | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.450 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 4h3q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.450 | |
| 4nk9 | 2K5 | Fibroblast growth factor receptor 1 | / | 0.450 | |
| 4oj4 | DIF | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 2c6k | DT2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2dwb | ANP | Aurora kinase A | 2.7.11.1 | 0.449 | |
| 2f02 | ATP | Tagatose-6-phosphate kinase | / | 0.449 | |
| 2i40 | BLZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2ijm | ATP | Focal adhesion kinase 1 | 2.7.10.2 | 0.449 | |
| 2pvk | P45 | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 2wih | P48 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.449 | |
| 3nyn | SGV | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.449 | |
| 3s1h | 56Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3sw4 | 18K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.449 | |
| 4a7c | E46 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 4bco | T6Q | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 4btj | ADP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.449 | |
| 4dta | ADN | APH(2'')-Id | / | 0.449 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.449 | |
| 1wvx | BD4 | Death-associated protein kinase 1 | 2.7.11.1 | 0.448 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.448 | |
| 2vtq | LZA | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 3bpt | QUE | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial | 3.1.2.4 | 0.448 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.448 | |
| 3nwq | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3rah | O1Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 4bqp | VMY | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4pkl | 1GH | Uncharacterized protein | / | 0.448 | |
| 1oi9 | N20 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 1zhw | HC2 | Oxysterol-binding protein homolog 4 | / | 0.447 | |
| 2hl2 | SSA | Threonine--tRNA ligase | 6.1.1.3 | 0.447 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.447 | |
| 3zze | 6XP | Hepatocyte growth factor receptor | 2.7.10.1 | 0.447 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.447 | |
| 4gu9 | 4GU | Focal adhesion kinase 1 | 2.7.10.2 | 0.447 | |
| 4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 1gih | 1PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 1ol7 | ADP | Aurora kinase A | 2.7.11.1 | 0.446 | |
| 1pmv | 537 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.446 | |
| 1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.446 | |
| 2uze | C95 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.446 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.446 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.446 | |
| 4awi | AQ2 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.446 | |
| 4dn5 | AGS | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.446 | |
| 4fkl | CK2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.446 | |
| 4oh4 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.446 | |
| 5eyp | LOC | Tubulin beta chain | / | 0.446 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.445 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.445 | |
| 2r9e | SDX | Citrate synthase | 2.3.3.16 | 0.445 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.445 | |
| 3a60 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.445 | |
| 3a7h | ATP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.445 | |
| 3ma3 | 01I | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 3o0g | 3O0 | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.445 | |
| 3ori | AGS | Serine/threonine protein kinase | / | 0.445 | |
| 3r7u | X96 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.445 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.445 | |
| 4fkw | 62K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 4ful | 0VU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4jqe | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 4q5h | ANP | Protein kinase OspG | 2.7 | 0.445 | |
| 5dr9 | SKE | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 5e8y | STU | TGF-beta receptor type-2 | 2.7.11.30 | 0.445 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.445 | |
| 1gii | 1PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.444 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2bxo | OPB | Serum albumin | / | 0.444 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.444 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.444 | |
| 3eem | 53V | Uncharacterized protein | / | 0.444 | |
| 3fsu | C2F | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.444 | |
| 3iod | A6D | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 3kvx | FMY | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.444 | |
| 3qd0 | 3Q4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 3w8q | AGS | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.444 | |
| 4bcm | T7Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 4loq | SB4 | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 4oti | MI1 | Serine/threonine-protein kinase N1 | / | 0.444 | |
| 5drd | ATP | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.444 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.443 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.443 | |
| 1m17 | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 1sdu | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 2gu8 | 796 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 3i4b | Z48 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.443 | |
| 3oev | 3OE | Proteasome subunit beta type-5 | 3.4.25.1 | 0.443 | |
| 3oev | 3OE | Proteasome subunit beta type-6 | 3.4.25.1 | 0.443 | |
| 3okx | SAM | S-adenosyl-L-methionine-binding protein RPA0152 | / | 0.443 | |
| 3w55 | 1FM | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.443 | |
| 4e73 | 0NR | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.443 | |
| 4f70 | 0ST | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.443 | |
| 4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.443 | |
| 4kb8 | 1QO | Casein kinase I isoform delta | 2.7.11.1 | 0.443 | |
| 4l8u | 9AZ | Serum albumin | / | 0.443 | |
| 4u03 | GTP | Cyclic GMP-AMP synthase | / | 0.443 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.442 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.442 | |
| 2b1p | AIZ | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.442 | |
| 2b9f | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.442 | |
| 2vu3 | LZE | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2wtc | VGM | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.442 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3rni | 21Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3uli | 1N3 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4g73 | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.442 | |
| 4gyi | ADP | Uncharacterized protein | / | 0.442 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.442 | |
| 4lrz | ADP | PEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL | 2.7 | 0.442 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.442 | |
| 4r8q | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.442 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.442 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1p2a | 5BN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 1sj0 | E4D | Estrogen receptor | / | 0.441 | |
| 1stc | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 1w8c | N69 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 1xkk | FMM | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.441 | |
| 2j2i | LY4 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.441 | |
| 2ydw | WSH | Bromodomain-containing protein 2 | / | 0.441 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.441 | |
| 3jxw | LXG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 3qly | 55V | Uncharacterized protein | / | 0.441 | |
| 4hvi | 19S | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.441 | |
| 4lm5 | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 4qmy | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.441 | |
| 5dt4 | ATP | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 1cx4 | CMP | cAMP-dependent protein kinase type II-beta regulatory subunit | / | 0.440 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.440 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.440 | |
| 1pxl | CK4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.440 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 1yi4 | ADN | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.440 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.440 | |
| 2ojj | 82A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.440 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.440 | |
| 3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 3qqg | X06 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3r9d | X6B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3ral | 04Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3rvg | 17P | Tyrosine-protein kinase JAK2 | / | 0.440 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.440 | |
| 4bl1 | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.440 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.440 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.440 | |
| 4oa9 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.440 | |
| 4zas | TYD | CalS13 | / | 0.440 |