Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3rjc06ZCyclin-dependent kinase 22.7.11.22

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3rjc06ZCyclin-dependent kinase 22.7.11.221.000
3r9dX6BCyclin-dependent kinase 22.7.11.220.692
3rpv26ZCyclin-dependent kinase 22.7.11.220.654
3s1h56ZCyclin-dependent kinase 22.7.11.220.643
2b52D42Cyclin-dependent kinase 22.7.11.220.635
2r3lSCWCyclin-dependent kinase 22.7.11.220.634
3qtrX36Cyclin-dependent kinase 22.7.11.220.629
3rak03ZCyclin-dependent kinase 22.7.11.220.624
3rni21ZCyclin-dependent kinase 22.7.11.220.624
3qtzX42Cyclin-dependent kinase 22.7.11.220.623
3ral04ZCyclin-dependent kinase 22.7.11.220.619
3lfnA27Cyclin-dependent kinase 22.7.11.220.618
3sqq99ZCyclin-dependent kinase 22.7.11.220.617
4acm7YGCyclin-dependent kinase 22.7.11.220.612
1v1k3FPCyclin-dependent kinase 22.7.11.220.609
3rmf20ZCyclin-dependent kinase 22.7.11.220.607
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.604
3qu0X40Cyclin-dependent kinase 22.7.11.220.603
2b55D31Cyclin-dependent kinase 22.7.11.220.602
4fkq42KCyclin-dependent kinase 22.7.11.220.602
1pxmCK5Cyclin-dependent kinase 22.7.11.220.599
3rm618ZCyclin-dependent kinase 22.7.11.220.598
3qxoX65Cyclin-dependent kinase 22.7.11.220.597
1w0xOLOCyclin-dependent kinase 22.7.11.220.596
2r3kSCQCyclin-dependent kinase 22.7.11.220.596
3s0o50ZCyclin-dependent kinase 22.7.11.220.593
1gih1PUCyclin-dependent kinase 22.7.11.220.590
3qzgX67Cyclin-dependent kinase 22.7.11.220.590
3pj8404Cyclin-dependent kinase 22.7.11.220.589
2w17I19Cyclin-dependent kinase 22.7.11.220.587
3rm719ZCyclin-dependent kinase 22.7.11.220.585
3rk909ZCyclin-dependent kinase 22.7.11.220.584
1ke6LS2Cyclin-dependent kinase 22.7.11.220.582
4bgh3I6Cyclin-dependent kinase 22.7.11.220.581
2w06FRVCyclin-dependent kinase 22.7.11.220.580
3rk507ZCyclin-dependent kinase 22.7.11.220.580
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.579
2w1hL0FCyclin-dependent kinase 22.7.11.220.579
1ke9LS5Cyclin-dependent kinase 22.7.11.220.578
1urwI1PCyclin-dependent kinase 22.7.11.220.578
1h1r6CPCyclin-dependent kinase 22.7.11.220.577
2c6o4SPCyclin-dependent kinase 22.7.11.220.577
2fvdLIACyclin-dependent kinase 22.7.11.220.577
4fkr45KCyclin-dependent kinase 22.7.11.220.577
3qqkX02Cyclin-dependent kinase 22.7.11.220.576
3qtuX44Cyclin-dependent kinase 22.7.11.220.576
3unk0BYCyclin-dependent kinase 22.7.11.220.576
2r3p3SCCyclin-dependent kinase 22.7.11.220.575
3ezvEZVCyclin-dependent kinase 22.7.11.220.575
2iw84SPCyclin-dependent kinase 22.7.11.220.574
2j9mPY8Cyclin-dependent kinase 22.7.11.220.574
3iggEFQCyclin-dependent kinase 22.7.11.220.574
3qxpX64Cyclin-dependent kinase 22.7.11.220.574
3r9hZ67Cyclin-dependent kinase 22.7.11.220.571
3s2pPMUCyclin-dependent kinase 22.7.11.220.571
1oguST8Cyclin-dependent kinase 22.7.11.220.570
1oitHDTCyclin-dependent kinase 22.7.11.220.570
1p2a5BNCyclin-dependent kinase 22.7.11.220.568
4fkpLS5Cyclin-dependent kinase 22.7.11.220.566
2a0cCK9Cyclin-dependent kinase 22.7.11.220.565
3r7yZ04Cyclin-dependent kinase 22.7.11.220.565
1h1s4SPCyclin-dependent kinase 22.7.11.220.564
3qtxX43Cyclin-dependent kinase 22.7.11.220.564
2r64740Cyclin-dependent kinase 22.7.11.220.563
1g5sI17Cyclin-dependent kinase 22.7.11.220.561
2btrU73Cyclin-dependent kinase 22.7.11.220.560
2vv9IM9Cyclin-dependent kinase 22.7.11.220.560
3ti1B49Cyclin-dependent kinase 22.7.11.220.560
4fkv61KCyclin-dependent kinase 22.7.11.220.560
3r6xX84Cyclin-dependent kinase 22.7.11.220.559
3unj0BXCyclin-dependent kinase 22.7.11.220.559
3ig7EFPCyclin-dependent kinase 22.7.11.220.557
3rk708ZCyclin-dependent kinase 22.7.11.220.557
1fvt106Cyclin-dependent kinase 22.7.11.220.556
2uznC96Cyclin-dependent kinase 22.7.11.220.556
2iw94SPCyclin-dependent kinase 22.7.11.220.555
3r7iX9ICyclin-dependent kinase 22.7.11.220.555
4fx360KCyclin-dependent kinase 22.7.11.220.555
2w05FRTCyclin-dependent kinase 22.7.11.220.554
3r8lZ30Cyclin-dependent kinase 22.7.11.220.554
3qzhX69Cyclin-dependent kinase 22.7.11.220.553
1e9hINRCyclin-dependent kinase 22.7.11.220.552
1ke7LS3Cyclin-dependent kinase 22.7.11.220.552
3roy22ZCyclin-dependent kinase 22.7.11.220.552
3qqhX0ACyclin-dependent kinase 22.7.11.220.550
4fkw62KCyclin-dependent kinase 22.7.11.220.548
3ddpRC8Cyclin-dependent kinase 22.7.11.220.547
4fkt48KCyclin-dependent kinase 22.7.11.220.547
1ckpPVBCyclin-dependent kinase 22.7.11.220.545
1oi9N20Cyclin-dependent kinase 22.7.11.220.544
2r3jSCJCyclin-dependent kinase 22.7.11.220.544
1gii1PUCyclin-dependent kinase 22.7.11.220.542
2c6iDT1Cyclin-dependent kinase 22.7.11.220.542
3rkb12ZCyclin-dependent kinase 22.7.11.220.540
4erwSTUCyclin-dependent kinase 22.7.11.220.540
1ke5LS1Cyclin-dependent kinase 22.7.11.220.539
3ddqRRCCyclin-dependent kinase 22.7.11.220.539
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.538
4ek816KCyclin-dependent kinase 22.7.11.220.538
2uzoC62Cyclin-dependent kinase 22.7.11.220.537
4bcpT3CCyclin-dependent kinase 22.7.11.220.535
2xmyCDKCyclin-dependent kinase 22.7.11.220.533
3r1yX76Cyclin-dependent kinase 22.7.11.220.533
1y91CT9Cyclin-dependent kinase 22.7.11.220.531
2r3iSCFCyclin-dependent kinase 22.7.11.220.531
4ez30S0Cyclin-dependent kinase 22.7.11.220.531
2r3mSCXCyclin-dependent kinase 22.7.11.220.530
4eor4SPCyclin-dependent kinase 22.7.11.220.529
4fko20KCyclin-dependent kinase 22.7.11.220.529
4fkg4CKCyclin-dependent kinase 22.7.11.220.528
1pxkCK3Cyclin-dependent kinase 22.7.11.220.527
1vyw292Cyclin-dependent kinase 22.7.11.220.527
3r9oZ71Cyclin-dependent kinase 22.7.11.220.527
1oiqHDUCyclin-dependent kinase 22.7.11.220.526
3r28XA0Cyclin-dependent kinase 22.7.11.220.526
3r73X87Cyclin-dependent kinase 22.7.11.220.526
3r83Z14Cyclin-dependent kinase 22.7.11.220.526
4ek610KCyclin-dependent kinase 22.7.11.220.526
1oiuN76Cyclin-dependent kinase 22.7.11.220.524
1w8cN69Cyclin-dependent kinase 22.7.11.220.524
2a4lRRCCyclin-dependent kinase 22.7.11.220.524
3pxyJWSCyclin-dependent kinase 22.7.11.220.524
3r8vZ62Cyclin-dependent kinase 22.7.11.220.524
3rpo24ZCyclin-dependent kinase 22.7.11.220.524
2duv371Cyclin-dependent kinase 22.7.11.220.523
3lfqA28Cyclin-dependent kinase 22.7.11.220.523
3r7vZ02Cyclin-dependent kinase 22.7.11.220.523
2btsU32Cyclin-dependent kinase 22.7.11.220.522
3py0SU9Cyclin-dependent kinase 22.7.11.220.522
3s00Z60Cyclin-dependent kinase 22.7.11.220.522
1r78FMDCyclin-dependent kinase 22.7.11.220.521
4lyn1YGCyclin-dependent kinase 22.7.11.220.521
1h1q2A6Cyclin-dependent kinase 22.7.11.220.520
3r1sX73Cyclin-dependent kinase 22.7.11.220.520
2vttLZDCyclin-dependent kinase 22.7.11.220.519
3r1qX75Cyclin-dependent kinase 22.7.11.220.519
3r7uX96Cyclin-dependent kinase 22.7.11.220.519
3sw418KCyclin-dependent kinase 22.7.11.220.519
1pkdUCNCyclin-dependent kinase 22.7.11.220.518
2vu3LZECyclin-dependent kinase 22.7.11.220.518
3qqlX03Cyclin-dependent kinase 22.7.11.220.518
3sw719KCyclin-dependent kinase 22.7.11.220.518
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.517
3raiX85Cyclin-dependent kinase 22.7.11.220.517
4bcnT9NCyclin-dependent kinase 22.7.11.220.517
1ke8LS4Cyclin-dependent kinase 22.7.11.220.516
1vyzN5BCyclin-dependent kinase 22.7.11.220.516
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.516
2vtsLZCCyclin-dependent kinase 22.7.11.220.516
3qruX19Cyclin-dependent kinase 22.7.11.220.516
3qwkX62Cyclin-dependent kinase 22.7.11.220.516
2r3o2SCCyclin-dependent kinase 22.7.11.220.515
4eok4SPCyclin-dependent kinase 22.7.11.220.515
1oiyN41Cyclin-dependent kinase 22.7.11.220.514
3r7eX88Cyclin-dependent kinase 22.7.11.220.514
3uli1N3Cyclin-dependent kinase 22.7.11.220.514
2wxvWXVCyclin-dependent kinase 22.7.11.220.513
4fks46KCyclin-dependent kinase 22.7.11.220.513
1di8DTQCyclin-dependent kinase 22.7.11.220.512
1pyePM1Cyclin-dependent kinase 22.7.11.220.512
3qwjX6ACyclin-dependent kinase 22.7.11.220.511
3qtqX35Cyclin-dependent kinase 22.7.11.220.510
2bhhRYUCyclin-dependent kinase 22.7.11.220.509
2r3gSC9Cyclin-dependent kinase 22.7.11.220.509
3wblPDYCyclin-dependent kinase 22.7.11.220.509
1unlRRCCyclin-dependent-like kinase 52.7.11.10.508
3r8zZ63Cyclin-dependent kinase 22.7.11.220.506
1gij2PUCyclin-dependent kinase 22.7.11.220.505
1oirHDYCyclin-dependent kinase 22.7.11.220.504
1pxlCK4Cyclin-dependent kinase 22.7.11.220.504
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.504
3dogNNNCyclin-dependent kinase 22.7.11.220.504
3ezrEZRCyclin-dependent kinase 22.7.11.220.504
4bcmT7ZCyclin-dependent kinase 22.7.11.220.504
4fkj11KCyclin-dependent kinase 22.7.11.220.504
2xnbY8LCyclin-dependent kinase 22.7.11.220.503
1ykr628Cyclin-dependent kinase 22.7.11.220.501
2x1nX1NCyclin-dependent kinase 22.7.11.220.501
4fki09KCyclin-dependent kinase 22.7.11.220.501
2bheBRYCyclin-dependent kinase 22.7.11.220.500
2r3r6SCCyclin-dependent kinase 22.7.11.220.500
3tiz3TICyclin-dependent kinase 22.7.11.220.500
1aq1STUCyclin-dependent kinase 22.7.11.220.498
3ql8X01Cyclin-dependent kinase 22.7.11.220.498
3r71X86Cyclin-dependent kinase 22.7.11.220.497
3qrtX14Cyclin-dependent kinase 22.7.11.220.496
4eon1ROCyclin-dependent kinase 22.7.11.220.496
1h1pCMGCyclin-dependent kinase 22.7.11.220.495
2wpa889Cyclin-dependent kinase 22.7.11.220.494
2i40BLZCyclin-dependent kinase 22.7.11.220.493
3qtwX3ACyclin-dependent kinase 22.7.11.220.493
3rzb02ZCyclin-dependent kinase 22.7.11.220.492
2c5yMTWCyclin-dependent kinase 22.7.11.220.491
2c6tDT5Cyclin-dependent kinase 22.7.11.220.491
3qx2X63Cyclin-dependent kinase 22.7.11.220.491
4kd11QKCyclin-dependent kinase 22.7.11.220.490
1h0vUN4Cyclin-dependent kinase 22.7.11.220.488
3rpy27ZCyclin-dependent kinase 22.7.11.220.488
3lfsA07Cyclin-dependent kinase 22.7.11.220.486
3qziX72Cyclin-dependent kinase 22.7.11.220.486
2r3fSC8Cyclin-dependent kinase 22.7.11.220.485
2r3q5SCCyclin-dependent kinase 22.7.11.220.485
3r8pZ46Cyclin-dependent kinase 22.7.11.220.485
2c4g514Cyclin-dependent kinase 22.7.11.220.484
1pxpCK8Cyclin-dependent kinase 22.7.11.220.481
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.481
3o0g3O0Cyclin-dependent-like kinase 52.7.11.10.479
3qqfX07Cyclin-dependent kinase 22.7.11.220.479
3fz1B98Cyclin-dependent kinase 22.7.11.220.478
4bcoT6QCyclin-dependent kinase 22.7.11.220.478
4qmpDKISerine/threonine-protein kinase 242.7.11.10.478
3sheI85MAP kinase-activated protein kinase 32.7.11.10.477
1fvv107Cyclin-dependent kinase 22.7.11.220.476
2uzbC75Cyclin-dependent kinase 22.7.11.220.476
1h0w207Cyclin-dependent kinase 22.7.11.220.474
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.473
2b54D05Cyclin-dependent kinase 22.7.11.220.472
3rpr25ZCyclin-dependent kinase 22.7.11.220.472
2vtqLZACyclin-dependent kinase 22.7.11.220.471
2c5nCK8Cyclin-dependent kinase 22.7.11.220.470
1pxoCK7Cyclin-dependent kinase 22.7.11.220.469
2c6mDT5Cyclin-dependent kinase 22.7.11.220.469
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.468
2wihP48Cyclin-dependent kinase 22.7.11.220.467
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.466
4eos1ROCyclin-dependent kinase 22.7.11.220.466
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.465
2uzdC85Cyclin-dependent kinase 22.7.11.220.465
3tnwF18Cyclin-dependent kinase 22.7.11.220.465
4eoi1ROCyclin-dependent kinase 22.7.11.220.465
3qtsX46Cyclin-dependent kinase 22.7.11.220.464
2uzeC95Cyclin-dependent kinase 22.7.11.220.463
4ez50RSCyclin-dependent kinase 62.7.11.220.463
3my5RFZCyclin-dependent kinase 22.7.11.220.461
3rahO1ZCyclin-dependent kinase 22.7.11.220.461
2c69CT8Cyclin-dependent kinase 22.7.11.220.460
4eol1ROCyclin-dependent kinase 22.7.11.220.460
1dm2HMDCyclin-dependent kinase 22.7.11.220.459
4eop1ROCyclin-dependent kinase 22.7.11.220.459
2qd7065Gag-Pol polyprotein3.4.23.160.457
2wotZZGTGF-beta receptor type-12.7.11.300.456
3r8uZ31Cyclin-dependent kinase 22.7.11.220.456
3zep1NXTyrosine-protein kinase JAK32.7.10.20.456
3le62BZCyclin-dependent kinase 22.7.11.220.455
3qzfX66Cyclin-dependent kinase 22.7.11.220.455
2b53D23Cyclin-dependent kinase 22.7.11.220.453
3at3ATKCasein kinase II subunit alpha2.7.11.10.453
4kioG5KTyrosine-protein kinase ITK/TSK2.7.10.20.452
1y8yCT7Cyclin-dependent kinase 22.7.11.220.451
2eufLQQCyclin-dependent kinase 62.7.11.220.451
2f2cAP9Cyclin-dependent kinase 62.7.11.220.451
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.451
1xjdSTUProtein kinase C theta type2.7.11.130.450
3ggaGGWGag-Pol polyprotein/0.450
3r9nZ68Cyclin-dependent kinase 22.7.11.220.450
4fv9E71Mitogen-activated protein kinase 12.7.11.240.450
1v0oINRCell division control protein 2 homolog2.7.11.220.449
2cchATPCyclin-dependent kinase 22.7.11.220.449
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.449
2pvnP63Casein kinase II subunit alpha2.7.11.10.449
3at4CCKCasein kinase II subunit alpha2.7.11.10.449
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.447
2vthLZ2Cyclin-dependent kinase 22.7.11.220.446
3be9P04Casein kinase II subunit alpha2.7.11.10.446
3ggfGVDSerine/threonine-protein kinase 26/0.446
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.446
2c6kDT2Cyclin-dependent kinase 22.7.11.220.445
2c6lDT4Cyclin-dependent kinase 22.7.11.220.444
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.443
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.443
4cfnJYMCyclin-dependent kinase 22.7.11.220.442
3nux3NVCyclin-dependent kinase 62.7.11.220.440