Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3rhqNAPCytosolic 10-formyltetrahydrofolate dehydrogenase1.5.1.6

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3rhqNAPCytosolic 10-formyltetrahydrofolate dehydrogenase1.5.1.61.000
4gnzNAPCytosolic 10-formyltetrahydrofolate dehydrogenase1.5.1.60.646
3rhrNDPCytosolic 10-formyltetrahydrofolate dehydrogenase1.5.1.60.551
1a4zNADAldehyde dehydrogenase, mitochondrial1.2.1.30.545
1o01NADAldehyde dehydrogenase, mitochondrial1.2.1.30.538
1wnbNAIGamma-aminobutyraldehyde dehydrogenase1.2.1.190.529
4zz7NADMethylmalonate-semialdehyde dehydrogenase/0.529
2onpNADAldehyde dehydrogenase, mitochondrial1.2.1.30.528
1o00NADAldehyde dehydrogenase, mitochondrial1.2.1.30.519
3rhjNAPCytosolic 10-formyltetrahydrofolate dehydrogenase1.5.1.60.519
3rhlNAPCytosolic 10-formyltetrahydrofolate dehydrogenase1.5.1.60.509
4i8pNADAminoaldehyde dehydrogenase 1/0.502
3v9lNADDelta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial1.2.1.880.491
1uxvNAPNAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase/0.470
3lnsNAPNAD(P)-dependent benzaldehyde dehydrogenase1.2.1.280.469
4pt0NADAldehyde dehydrogenase/0.459
5dibNADBetaine-aldehyde dehydrogenase/0.456