sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3rhd | NAP | Lactaldehyde dehydrogenase | 1.2.1.22 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3rhd | NAP | Lactaldehyde dehydrogenase | 1.2.1.22 | 1.000 | |
| 2esd | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.9 | 0.511 | |
| 3rhh | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.489 | |
| 2j6l | NAI | Alpha-aminoadipic semialdehyde dehydrogenase | 1.2.1.31 | 0.460 | |
| 1o02 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.459 | |
| 2bhp | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.455 | |
| 2ehq | NAP | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.454 | |
| 1uxn | NAP | NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.451 | |
| 2j40 | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.450 | |
| 4zz7 | NAD | Methylmalonate-semialdehyde dehydrogenase | / | 0.447 | |
| 4pxl | NAD | Aldehyde dehydrogenase3 | / | 0.446 | |
| 2ehu | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.444 | |
| 1o01 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.442 | |
| 2wme | NAP | NAD/NADP-dependent betaine aldehyde dehydrogenase | / | 0.441 |