sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3rh7 | FMN | Uncharacterized protein |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3rh7 | FMN | Uncharacterized protein | / | 1.000 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.485 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.484 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.475 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.469 | |
| 2h2e | SA8 | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.466 | |
| 3a20 | FMN | FMN-binding protein | / | 0.466 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.463 | |
| 4blr | UTP | NTPase P4 | / | 0.463 | |
| 3ojx | FAD | NADPH--cytochrome P450 reductase | / | 0.461 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.461 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.460 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.457 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.457 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.457 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.457 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.454 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.454 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.452 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.452 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.451 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.451 | |
| 1rz1 | FAD | Phenol 2-hydroxylase component B | / | 0.450 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.450 | |
| 3vx4 | ATP | Putative ABC transporter, ATP-binding protein ComA | / | 0.450 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.449 | |
| 1hku | NAD | C-terminal-binding protein 1 | 1.1.1 | 0.446 | |
| 2ed4 | FAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.446 | |
| 3omu | IBD | Heat shock protein 83 | / | 0.446 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.445 | |
| 1ykf | NAP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.445 | |
| 2h21 | SAM | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.445 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.444 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.444 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.444 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.443 | |
| 2is0 | I03 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.442 | |
| 2p2q | PRX | Acetyl-coenzyme A synthetase | / | 0.442 | |
| 2p2b | PRX | Acetyl-coenzyme A synthetase | / | 0.441 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.441 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.440 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.440 | |
| 3oix | FMN | Dihydroorotate dehydrogenase | / | 0.440 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.440 |