Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3qv2 | SAH | 5-cytosine DNA methyltransferase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3qv2 | SAH | 5-cytosine DNA methyltransferase | / | 1.000 | |
| 4h0n | SAH | Dnmt2 | / | 0.512 | |
| 7mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.503 | |
| 5mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.502 | |
| 8mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.497 | |
| 9mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.497 | |
| 2uyh | SAH | Modification methylase HhaI | 2.1.1.37 | 0.495 | |
| 1skm | SAH | Modification methylase HhaI | 2.1.1.37 | 0.492 | |
| 3pt6 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.491 | |
| 2zcj | SAH | Modification methylase HhaI | 2.1.1.37 | 0.489 | |
| 4wxx | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.487 | |
| 1mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.468 | |
| 2hmy | SAM | Modification methylase HhaI | 2.1.1.37 | 0.468 | |
| 2z6u | SAH | Modification methylase HhaI | 2.1.1.37 | 0.464 | |
| 3pt9 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.458 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 2i9k | SAH | Modification methylase HhaI | 2.1.1.37 | 0.453 | |
| 4da4 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.452 | |
| 10mh | SAH | Modification methylase HhaI | 2.1.1.37 | 0.449 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.447 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2c7q | SAH | Modification methylase HhaI | 2.1.1.37 | 0.446 | |
| 1fjx | SAH | Modification methylase HhaI | 2.1.1.37 | 0.444 |