sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3qus | AGS | Formate--tetrahydrofolate ligase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3qus | AGS | Formate--tetrahydrofolate ligase | / | 1.000 | |
| 3ty3 | GGG | Homoisocitrate dehydrogenase | 1.1.1.87 | 0.483 | |
| 3swq | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.476 | |
| 2x3f | APC | Pantothenate synthetase | / | 0.468 | |
| 4en4 | ATP | Pyridoxal kinase | 2.7.1.35 | 0.458 | |
| 4fry | NAD | Putative signal-transduction protein with CBS domains | / | 0.454 | |
| 1ci0 | FMN | Pyridoxamine 5'-phosphate oxidase | 1.4.3.5 | 0.450 | |
| 5aga | ANP | DNA polymerase theta | / | 0.450 | |
| 3fwy | ADP | Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein | / | 0.447 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.446 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.445 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.445 | |
| 1ryw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.444 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.444 | |
| 1n2e | APC | Pantothenate synthetase | 6.3.2.1 | 0.443 | |
| 1ylu | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.443 | |
| 4c13 | UML | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase | / | 0.443 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.442 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.442 | |
| 3ukf | GDU | UDP-galactopyranose mutase | / | 0.442 | |
| 2nli | FMN | Lactate oxidase | / | 0.441 | |
| 4n9i | PCG | Catabolite expression activator | / | 0.441 | |
| 1jed | ADP | Sulfate adenylyltransferase | / | 0.440 | |
| 1s4o | GDP | Glycolipid 2-alpha-mannosyltransferase | / | 0.440 | |
| 2rl1 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.440 | |
| 4giu | 636 | Anthranilate phosphoribosyltransferase | / | 0.440 |