Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3qj7UMPThymidylate synthase ThyA

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3qj7UMPThymidylate synthase ThyA/1.000
4irrUMPThymidylate synthase/0.600
5by6UMPThymidylate synthase/0.579
1bidUMPThymidylate synthase/0.554
3dgaUMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.541
2g8aUMPThymidylate synthase/0.540
4h0uUMPThymidylate synthase/0.532
4dpdUMPBifunctional dihydrofolate reductase-thymidylate synthase/0.530
4eb4UMPThymidylate synthase2.1.1.450.525
1jmgUMPThymidylate synthase/0.523
4einNOHThymidylate synthase2.1.1.450.520
3dg8UMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.518
1njeDCMThymidylate synthase/0.516
2vetUMPThymidylate synthase/0.511
2g86UMPThymidylate synthase/0.509
1jmfUMPThymidylate synthase/0.506
4e5oUMPThymidylate synthase2.1.1.450.506
1njdUMPThymidylate synthase/0.502
4dq1UMPThymidylate synthase/0.498
1ci7UMPThymidylate synthase2.1.1.450.497
4iskUMPThymidylate synthase/0.497
4psgNOHThymidylate synthase/0.494
1njbUMPThymidylate synthase/0.485
3bgxTMPThymidylate synthase/0.484
2tdmUMPThymidylate synthase/0.482
1njcDCMThymidylate synthase/0.480
2g89UMPThymidylate synthase/0.479
2g8dUMPThymidylate synthase/0.479
1bduDURThymidylate synthase/0.478
4xsdUMPThymidylate synthase2.1.1.450.476
2tsrUMPThymidylate synthase2.1.1.450.473
1tsyUMPThymidylate synthase/0.472
1jmiUMPThymidylate synthase/0.471
1njaDCMThymidylate synthase/0.470
1tsvUMPThymidylate synthase/0.462
1aobDDUThymidylate synthase/0.458
4foxUMPThymidylate synthase ThyA/0.457
1f28UMPThymidylate synthase2.1.1.450.449
1tsxUMPThymidylate synthase/0.443