sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3qch | NX2 | Receptor-type tyrosine-protein phosphatase gamma | 3.1.3.48 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3qch | NX2 | Receptor-type tyrosine-protein phosphatase gamma | 3.1.3.48 | 1.000 | |
| 3qcl | NXV | Receptor-type tyrosine-protein phosphatase gamma | 3.1.3.48 | 0.667 | |
| 3qci | NX3 | Receptor-type tyrosine-protein phosphatase gamma | 3.1.3.48 | 0.647 | |
| 3qck | NX5 | Receptor-type tyrosine-protein phosphatase gamma | 3.1.3.48 | 0.620 | |
| 3qcm | NXW | Receptor-type tyrosine-protein phosphatase gamma | 3.1.3.48 | 0.592 | |
| 3qcf | NXY | Receptor-type tyrosine-protein phosphatase gamma | 3.1.3.48 | 0.536 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.514 | |
| 3qce | NXY | Receptor-type tyrosine-protein phosphatase gamma | 3.1.3.48 | 0.507 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.502 | |
| 1o6r | R19 | Squalene--hopene cyclase | 4.2.1.129 | 0.498 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.498 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.494 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.491 | |
| 5dq8 | FLF | Transcriptional enhancer factor TEF-4 | / | 0.490 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.487 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.486 | |
| 3qcj | NX4 | Receptor-type tyrosine-protein phosphatase gamma | 3.1.3.48 | 0.481 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.481 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.477 | |
| 3qly | 55V | Uncharacterized protein | / | 0.476 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.475 | |
| 3jwm | 5WB | Dihydrofolate reductase | / | 0.472 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.472 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.472 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.471 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.471 | |
| 2og8 | 1N8 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.471 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.471 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.471 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.471 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.471 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.470 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.470 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.470 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.469 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.469 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.468 | |
| 2chw | 039 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.468 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.468 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.468 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.468 | |
| 3d74 | NBB | Pheromone-binding protein ASP1 | / | 0.467 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.466 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.466 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 3h0a | D30 | Peroxisome proliferator-activated receptor gamma | / | 0.463 | |
| 3ict | COA | Coenzyme A disulfide reductase | / | 0.463 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.462 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.462 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.462 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.461 | |
| 1zhw | HC2 | Oxysterol-binding protein homolog 4 | / | 0.461 | |
| 3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.461 | |
| 3tdl | 11D | Serum albumin | / | 0.461 | |
| 4fgg | 0U5 | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 3ama | SKE | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.460 | |
| 3kbo | NDP | Glyoxylate/hydroxypyruvate reductase A | / | 0.460 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 3sgt | P09 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | / | 0.460 | |
| 4la0 | 198 | Serum albumin | / | 0.460 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.459 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.459 | |
| 3dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 3k2h | LYA | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.459 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 4a31 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.459 | |
| 1bq6 | COA | Chalcone synthase 2 | 2.3.1.74 | 0.458 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.458 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.458 | |
| 3frq | ERY | Erythromycin resistance repressor protein | / | 0.458 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.458 | |
| 3zux | TCH | Transporter | / | 0.458 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.458 | |
| 4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.458 | |
| 4m2x | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4ubs | DIF | Pentalenic acid synthase | 1.14.15.11 | 0.458 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2h44 | 7CA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.457 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.457 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.457 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.457 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.457 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.457 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.457 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.457 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.456 | |
| 2p4i | MR9 | Angiopoietin-1 receptor | 2.7.10.1 | 0.456 | |
| 2uzt | SS3 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.456 | |
| 3nwq | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.456 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.456 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.456 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.456 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.456 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.455 | |
| 2nr4 | FMN | Conserved protein | / | 0.455 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.455 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.455 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.455 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.455 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.455 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.454 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3up0 | D7S | aceDAF-12 | / | 0.454 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.454 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.454 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.454 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.454 | |
| 4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.454 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1mj3 | HXC | Enoyl-CoA hydratase, mitochondrial | 4.2.1.17 | 0.453 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.453 | |
| 3bej | MUF | Bile acid receptor | / | 0.453 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.453 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.453 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.453 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.453 | |
| 4dpm | COA | Malonyl-CoA reductase | 1.2.1.75 | 0.453 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1rc1 | KT3 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.452 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.452 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.452 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.452 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.452 | |
| 3dol | GWI | Pol protein | / | 0.452 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.452 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.452 | |
| 4jaq | COA | Alpha-pyrone synthesis polyketide synthase-like Pks11 | 2.3.1 | 0.452 | |
| 4xye | NAD | Formate dehydrogenase | / | 0.452 | |
| 1fml | RTL | Retinol dehydratase | / | 0.451 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.451 | |
| 1q4u | 4CA | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.451 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.451 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.451 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.451 | |
| 3wy0 | COA | Uncharacterized protein | / | 0.451 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.451 | |
| 5kcp | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.451 | |
| 1osv | CHC | Bile acid receptor | / | 0.450 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.450 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.450 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.450 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.450 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.450 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.450 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.450 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3gc8 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.450 | |
| 3h6k | 33T | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.450 | |
| 3m8p | 65B | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.450 | |
| 5a28 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 1kuv | CA5 | Serotonin N-acetyltransferase | / | 0.449 | |
| 1lco | PPY | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.449 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1ppj | SMA | Cytochrome b | / | 0.449 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.449 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.449 | |
| 2nsd | 4PI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.449 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.449 | |
| 3d76 | NBB | Pheromone-binding protein ASP1 | / | 0.449 | |
| 3ics | COA | Coenzyme A disulfide reductase | / | 0.449 | |
| 4kwi | 1TJ | Reductase homolog | / | 0.449 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.448 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.448 | |
| 1ii6 | ADP | Kinesin-like protein KIF11 | / | 0.448 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 1xds | DRA | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.448 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.448 | |
| 3vso | EK1 | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.448 | |
| 4l9k | EHF | Serum albumin | / | 0.448 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.447 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.447 | |
| 3vs3 | VSE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.447 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.447 | |
| 3w2c | N15 | Aurora kinase A | 2.7.11.1 | 0.447 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.446 | |
| 2x6d | X6D | Aurora kinase A | 2.7.11.1 | 0.446 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.446 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.446 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.446 | |
| 3vry | B43 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.446 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.446 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.446 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.446 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.446 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 2azy | CHD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.445 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.445 | |
| 2qd5 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.445 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.445 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.445 | |
| 3gbk | 2PQ | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.445 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.445 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.445 | |
| 4ktf | 1TM | Cytochrome P450 | / | 0.445 | |
| 4mle | VO1 | Glucokinase | 2.7.1.2 | 0.445 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.444 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.444 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.444 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.444 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.444 | |
| 2vxo | XMP | GMP synthase [glutamine-hydrolyzing] | 6.3.5.2 | 0.444 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.444 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.444 | |
| 3p6m | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3p9t | TCL | Repressor | / | 0.444 | |
| 3qlf | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.444 | |
| 3sa2 | 7DR | Dihydrofolate reductase | / | 0.444 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.444 | |
| 3v3m | 0EN | Replicase polyprotein 1a | 3.4.19.12 | 0.444 | |
| 4a95 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.444 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.444 | |
| 4gev | CB3 | Thymidylate synthase | / | 0.444 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.444 | |
| 4h3c | 0YZ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.444 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.444 | |
| 5doz | NDP | JamJ | / | 0.444 | |
| 1dg5 | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1eyq | NAR | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.443 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2bxi | AZQ | Serum albumin | / | 0.443 | |
| 2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.443 | |
| 2pe1 | 517 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.443 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.443 | |
| 3i68 | J4Z | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.443 | |
| 3neg | PYV | Abscisic acid receptor PYL1 | / | 0.443 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.443 | |
| 3t1a | 5MA | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 3wxy | COA | Uncharacterized protein | / | 0.443 | |
| 4c2z | MYA | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.443 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.443 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.443 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.443 | |
| 4tyj | 0LI | Fibroblast growth factor receptor 4 | 2.7.10.1 | 0.443 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.443 | |
| 2ycy | P32 | Beta-1 adrenergic receptor | / | 0.443 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.442 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1j7u | ANP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.442 | |
| 1nbm | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.442 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.442 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.442 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.442 | |
| 2rab | NAD | Glutathione amide reductase | / | 0.442 | |
| 2w5a | ADP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.442 | |
| 2wuu | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.442 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.442 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3ix9 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.442 | |
| 4elh | 53I | Dihydrofolate reductase | / | 0.442 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.442 | |
| 4l8u | 9AZ | Serum albumin | / | 0.442 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.442 | |
| 1cbr | REA | Cellular retinoic acid-binding protein 1 | / | 0.441 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1jxz | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.441 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.441 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.441 | |
| 1scu | COA | Succinate--CoA ligase [ADP-forming] subunit alpha | 6.2.1.5 | 0.441 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.441 | |
| 2nmt | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.441 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.441 | |
| 2wsi | FAD | FAD synthase | 2.7.7.2 | 0.441 | |
| 2yek | EAM | Bromodomain-containing protein 2 | / | 0.441 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.441 | |
| 3c7q | XIN | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.441 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.441 | |
| 4ejn | 0R4 | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.441 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.441 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4hw2 | 19H | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.441 | |
| 4irn | FAD | AnaB | / | 0.441 | |
| 4kbk | 1QG | Casein kinase I isoform delta | 2.7.11.1 | 0.441 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.441 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.441 | |
| 1buc | FAD | Acyl-CoA dehydrogenase, short-chain specific | 1.3.8.1 | 0.440 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.440 | |
| 1s7n | COA | Acetyl transferase | / | 0.440 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.440 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.440 | |
| 3eel | 53T | Uncharacterized protein | / | 0.440 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 3i6r | J5Z | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.440 | |
| 3ln1 | CEL | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.440 | |
| 3meg | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.440 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 3wgw | T2B | Proliferating cell nuclear antigen | / | 0.440 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4boe | CLR | Japanin | / | 0.440 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4f1s | F1S | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.440 | |
| 4g48 | PZB | Mycocyclosin synthase | 1.14.21.9 | 0.440 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.440 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.440 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.440 |