Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3q7fED2Uncharacterized protein

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3q7fED2Uncharacterized protein/1.000
3sfy3FYUncharacterized protein/0.751
3e33ED7Protein farnesyltransferase subunit beta2.5.1.580.623
2r2lPB9Protein farnesyltransferase subunit beta2.5.1.580.621
1s63778Protein farnesyltransferase subunit beta2.5.1.580.613
1o1s1NHProtein farnesyltransferase subunit beta2.5.1.580.607
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.600
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.594
3e30ED4Protein farnesyltransferase subunit beta2.5.1.580.592
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.591
1ld8U49Protein farnesyltransferase subunit beta2.5.1.580.587
1mzcBNEProtein farnesyltransferase subunit beta2.5.1.580.584
1jcq739Protein farnesyltransferase subunit beta2.5.1.580.583
2h6iCYS_VAL_LEU_SER_GERProtein farnesyltransferase subunit beta2.5.1.580.573
1sa4JANProtein farnesyltransferase subunit beta2.5.1.580.572
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.543
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.543
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.543
2f0y3MNProtein farnesyltransferase subunit beta2.5.1.580.521
2iejS48Protein farnesyltransferase subunit beta2.5.1.580.508
3pz43PZProtein farnesyltransferase subunit beta2.5.1.580.498
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.491
1n4sCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.479
1o1t2NHProtein farnesyltransferase subunit beta2.5.1.580.462
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.446
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.446
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.440