Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3pt6 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3pt6 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 1.000 | |
| 3pt9 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.498 | |
| 4wxx | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.479 | |
| 3swr | SFG | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.468 | |
| 7mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.466 | |
| 9mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.459 | |
| 1skm | SAH | Modification methylase HhaI | 2.1.1.37 | 0.453 | |
| 4da4 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.444 | |
| 8mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.443 |