sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3pgp | ACO | Uncharacterized protein |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3pgp | ACO | Uncharacterized protein | / | 1.000 | |
| 4kub | COA | Uncharacterized protein | / | 0.582 | |
| 1s5k | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.538 | |
| 4oae | CLM | Uncharacterized protein | / | 0.507 | |
| 4kvx | ACO | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.505 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.504 | |
| 1m4d | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.495 | |
| 4u9v | ACO | N-alpha-acetyltransferase 40 | 2.3.1 | 0.494 | |
| 4kvm | SER_ALA_SER_GLU_1XE | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.492 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.492 | |
| 4jwp | ACO | GCN5-related N-acetyltransferase | / | 0.488 | |
| 1s60 | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.487 | |
| 3dr8 | ACO | L-methionine sulfoximine/L-methionine sulfone acetyltransferase | / | 0.474 | |
| 4qvt | ACO | Acetyltransferase YpeA | 2.3.1 | 0.469 | |
| 1j4j | ACO | Acetyltransferase | 2.3.1 | 0.466 | |
| 3f8k | COA | Uncharacterized protein | / | 0.461 | |
| 3r1k | COA | N-acetyltransferase Eis | / | 0.461 | |
| 2nnh | REA | Cytochrome P450 2C8 | / | 0.456 | |
| 1yre | COA | Uncharacterized protein | / | 0.455 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.454 | |
| 1m4i | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.453 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.452 | |
| 4oad | CLM | Uncharacterized protein | / | 0.451 | |
| 1s7n | COA | Acetyl transferase | / | 0.448 | |
| 1qsm | ACO | Histone acetyltransferase HPA2 | / | 0.446 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.445 | |
| 1wwz | ACO | Uncharacterized protein | / | 0.444 | |
| 4jxr | ACO | Acetyltransferase | / | 0.443 | |
| 2vzz | SCA | Putative succinyl-CoA transferase Rv0802c | 2.8.3 | 0.442 | |
| 3k9u | ACO | Spermidine N(1)-acetyltransferase | / | 0.442 | |
| 3te4 | ACO | Dopamine N-acetyltransferase | / | 0.441 | |
| 3sxn | COA | N-acetyltransferase Eis | / | 0.440 |