sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3pgh | FLP | Prostaglandin G/H synthase 2 | 1.14.99.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3pgh | FLP | Prostaglandin G/H synthase 2 | 1.14.99.1 | 1.000 | |
| 1q4g | BFL | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.680 | |
| 4fm5 | DF0 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.638 | |
| 4cox | IMN | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.634 | |
| 1eqg | IBP | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.633 | |
| 1ht8 | 34C | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.626 | |
| 3n8w | FLP | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.624 | |
| 3ntg | D72 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.613 | |
| 1eqh | FLP | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.608 | |
| 2oye | IM8 | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.603 | |
| 3rr3 | FLR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.599 | |
| 3n8z | FLP | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.591 | |
| 4rrx | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.589 | |
| 3ln1 | CEL | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.587 | |
| 2ayl | FLP | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.575 | |
| 2oyu | IMS | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.572 | |
| 3n8x | NIM | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.572 | |
| 3q7d | NPX | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.572 | |
| 4ph9 | IBP | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.572 | |
| 3kk6 | CEL | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.555 | |
| 5ikr | ID8 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.539 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.527 | |
| 4rrw | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.520 | |
| 4rrz | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.520 | |
| 6cox | S58 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.508 | |
| 4oty | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.505 | |
| 3ln0 | 52B | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.500 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.498 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.490 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.489 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.489 | |
| 1ju6 | LYA | Thymidylate synthase | 2.1.1.45 | 0.488 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.487 | |
| 1kyz | FER | Caffeic acid 3-O-methyltransferase | 2.1.1.68 | 0.486 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.486 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.485 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.485 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.485 | |
| 3stx | BKA | Methylketone synthase I | / | 0.483 | |
| 4iae | 1DX | Alr2278 protein | / | 0.482 | |
| 1cbr | REA | Cellular retinoic acid-binding protein 1 | / | 0.481 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.481 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.479 | |
| 1qzf | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.479 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.479 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.479 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.478 | |
| 3frq | ERY | Erythromycin resistance repressor protein | / | 0.477 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.477 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.477 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.476 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.476 | |
| 1efv | FAD | Electron transfer flavoprotein subunit alpha, mitochondrial | / | 0.475 | |
| 3cwk | REA | Cellular retinoic acid-binding protein 2 | / | 0.475 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.475 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.474 | |
| 1sqv | UHD | Cytochrome b | / | 0.474 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.474 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.474 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.473 | |
| 3dl9 | V2H | Vitamin D 25-hydroxylase | / | 0.473 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.473 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.473 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.473 | |
| 1knu | YPA | Peroxisome proliferator-activated receptor gamma | / | 0.472 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.472 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.472 | |
| 2cbs | R13 | Cellular retinoic acid-binding protein 2 | / | 0.472 | |
| 2ic5 | GNP | Ras-related C3 botulinum toxin substrate 3 | / | 0.472 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.472 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.472 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.472 | |
| 1efp | FAD | Electron transfer flavoprotein subunit alpha | / | 0.471 | |
| 1i58 | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.471 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.471 | |
| 3n8y | DIF | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.471 | |
| 4m10 | ICD | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.471 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.471 | |
| 1pp9 | SMA | Cytochrome b | / | 0.470 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.470 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.470 | |
| 1dna | CB3 | Thymidylate synthase | / | 0.469 | |
| 1sqq | OST | Cytochrome b | / | 0.469 | |
| 1zhw | HC2 | Oxysterol-binding protein homolog 4 | / | 0.469 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.469 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.468 | |
| 3aba | FLI | Cytochrome P450 | / | 0.468 | |
| 3h1j | SMA | Cytochrome b | / | 0.468 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.468 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.467 | |
| 4cnj | FAD | L-amino acid oxidase | / | 0.467 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.467 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.466 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.466 | |
| 2a1u | FAD | Electron transfer flavoprotein subunit alpha, mitochondrial | / | 0.466 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.466 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.466 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.465 | |
| 1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.465 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.465 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.465 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.464 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.464 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.464 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.464 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.464 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.463 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.463 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.463 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.463 | |
| 4f1s | F1S | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.463 | |
| 1kk4 | ACO | Streptogramin A acetyltransferase | 2.3.1 | 0.462 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.462 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.462 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.462 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.462 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.462 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.462 | |
| 4zow | CLM | Multidrug transporter MdfA | / | 0.462 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.462 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.461 | |
| 2oxt | SAM | Genome polyprotein | / | 0.461 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.461 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.461 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.461 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.461 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.461 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.461 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 1zhz | ERG | Oxysterol-binding protein homolog 4 | / | 0.460 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 3kxo | KXO | Hematopoietic prostaglandin D synthase | / | 0.460 | |
| 3qly | 55V | Uncharacterized protein | / | 0.460 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.460 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.459 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.459 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.459 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.459 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.459 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.459 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.459 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.458 | |
| 2aib | ERG | Beta-elicitin cinnamomin | / | 0.458 | |
| 2b35 | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.458 | |
| 2qdx | FAD | Ferredoxin--NADP+ reductase | / | 0.458 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.458 | |
| 4u0k | 744 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.457 | |
| 1mc5 | AHE | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.457 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 1pow | FAD | Pyruvate oxidase | 1.2.3.3 | 0.457 | |
| 1pxx | DIF | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.457 | |
| 2vcq | D25 | Hematopoietic prostaglandin D synthase | / | 0.457 | |
| 3fl8 | RAR | Dihydrofolate reductase | / | 0.457 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.457 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.457 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.456 | |
| 1pox | FAD | Pyruvate oxidase | 1.2.3.3 | 0.456 | |
| 1rdt | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
| 2zpa | ADP | tRNA(Met) cytidine acetyltransferase TmcA | / | 0.456 | |
| 3lu6 | IMX | Serum albumin | / | 0.456 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.456 | |
| 4ez7 | 2AN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.456 | |
| 4ot2 | NPS | Serum albumin | / | 0.456 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.455 | |
| 1tdk | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.455 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2dbr | NAP | Glyoxylate reductase | 1.1.1.26 | 0.455 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.455 | |
| 2ic5 | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.455 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.455 | |
| 3d78 | NBB | Pheromone-binding protein ASP1 | / | 0.455 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.454 | |
| 1ezv | SMA | Cytochrome b | / | 0.454 | |
| 1kb9 | SMA | Cytochrome b | / | 0.454 | |
| 1osv | CHC | Bile acid receptor | / | 0.454 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.454 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.454 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 3ncg | BK1 | Calmodulin-domain protein kinase 1, putative | / | 0.454 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.454 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.454 | |
| 4fdp | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.454 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 1ikv | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 1sqp | MYX | Cytochrome b | / | 0.453 | |
| 2o0u | C0M | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.453 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.453 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.453 | |
| 4l3l | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.453 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.453 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.453 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.453 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.453 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1h2b | NAJ | NAD-dependent alcohol dehydrogenase | / | 0.452 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.452 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.452 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.452 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.452 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2yfe | YFE | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.452 | |
| 5eow | FAD | 6-hydroxynicotinate 3-monooxygenase | 1.14.13.114 | 0.452 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.451 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.451 | |
| 1kyo | SMA | Cytochrome b | / | 0.451 | |
| 1wlv | COA | Phenylacetic acid degradation protein PaaI | / | 0.451 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2nnh | REA | Cytochrome P450 2C8 | / | 0.451 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.451 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.451 | |
| 3lf0 | ATP | Nitrogen regulatory protein P-II | / | 0.451 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.451 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.450 | |
| 1m7a | MQU | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.450 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.450 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.450 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.450 | |
| 3cbs | R12 | Cellular retinoic acid-binding protein 2 | / | 0.450 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.450 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.450 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.450 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.450 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.450 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.450 | |
| 4tzk | 641 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 1fml | RTL | Retinol dehydratase | / | 0.449 | |
| 1fp1 | HCC | Isoliquiritigenin 2'-O-methyltransferase | / | 0.449 | |
| 1jvs | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.449 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.449 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.449 | |
| 2hnz | PC0 | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 2ibz | SMA | Cytochrome b | / | 0.449 | |
| 2q5p | 241 | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.449 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 3bej | MUF | Bile acid receptor | / | 0.449 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.449 | |
| 4ase | AV9 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.449 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.449 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4iah | 1DX | Alr2278 protein | / | 0.449 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.449 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.449 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.449 | |
| 4xr9 | TMP | CalS8 | / | 0.449 | |
| 1ci7 | CB3 | Thymidylate synthase | 2.1.1.45 | 0.448 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.448 | |
| 1juj | LYA | Thymidylate synthase | 2.1.1.45 | 0.448 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.448 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2agv | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.448 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.448 | |
| 2wes | FAD | Tryptophan 5-halogenase | / | 0.448 | |
| 2yiu | SMA | Cytochrome b | / | 0.448 | |
| 2zbz | VDX | Vitamin D3 dihydroxylase | / | 0.448 | |
| 2ze2 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 3oag | LPQ | Renin | 3.4.23.15 | 0.448 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.448 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.448 | |
| 4b7d | QLE | Cytochrome P450 monooxygenase PikC | / | 0.448 | |
| 4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.448 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.448 | |
| 4hw2 | 19H | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.448 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.448 | |
| 4oj4 | DIF | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 5ab7 | MLC | Nonspecific lipid-transfer protein, putative | / | 0.448 | |
| 5fkn | TDC | Tetracycline repressor protein class D | / | 0.448 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.447 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 2p4y | C03 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.447 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.447 | |
| 3ama | SKE | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.447 | |
| 4c3x | FAD | 3-ketosteroid dehydrogenase | / | 0.447 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.447 | |
| 4i3z | ADP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.447 | |
| 4qi7 | FAD | Cellobiose dehydrogenase | / | 0.447 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.447 | |
| 5ii2 | LU2 | Protein polybromo-1 | / | 0.447 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.446 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1tdo | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.446 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.446 | |
| 2fgj | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.446 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.446 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.446 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.446 | |
| 2ydf | IO3 | Serum albumin | / | 0.446 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.446 | |
| 4kf1 | HT5 | Aryldialkylphosphatase | 3.1.8.1 | 0.446 | |
| 4o5q | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.446 | |
| 4s33 | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.446 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.446 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.446 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.446 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1jut | LYD | Thymidylate synthase | / | 0.445 | |
| 1odn | APV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1w78 | PD8 | Dihydrofolate synthase/folylpolyglutamate synthase | 6.3.2.12 | 0.445 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.445 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2v1x | ADP | ATP-dependent DNA helicase Q1 | 3.6.4.12 | 0.445 | |
| 3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.445 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 4b14 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4crs | AGS | Serine/threonine-protein kinase N2 | 2.7.11.13 | 0.445 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.445 | |
| 4o8f | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.445 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 5d7p | OCZ | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.445 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.445 | |
| 5iw5 | NMN | NADH pyrophosphatase | / | 0.445 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.445 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.444 | |
| 1gjr | NAP | Ferredoxin--NADP reductase | 1.18.1.2 | 0.444 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.444 | |
| 1tdn | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.444 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.444 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.444 | |
| 2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.444 | |
| 2iut | AGS | DNA translocase FtsK | / | 0.444 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.444 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.444 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3jrx | S1A | Acetyl-CoA carboxylase 2 | / | 0.444 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.444 | |
| 3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.444 | |
| 3pm0 | BHF | Cytochrome P450 1B1 | / | 0.444 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.444 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 3zlm | ANP | Adenosine monophosphate-protein transferase NmFic | 2.7.7.n1 | 0.444 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.444 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.444 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.444 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.444 | |
| 4o7u | THF | Thymidylate synthase | / | 0.444 | |
| 4zs2 | FLU | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.444 | |
| 5ab6 | CAA | Nonspecific lipid-transfer protein, putative | / | 0.444 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.443 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.443 | |
| 1ie4 | T44 | Transthyretin | / | 0.443 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.443 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.443 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 1qvn | FRI | Interleukin-2 | / | 0.443 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.443 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2gtk | 208 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2ydw | WSH | Bromodomain-containing protein 2 | / | 0.443 | |
| 3cth | 319 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.443 | |
| 3cx5 | SMA | Cytochrome b | / | 0.443 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.443 | |
| 3stv | 3HO | Methylketone synthase I | / | 0.443 | |
| 3vs2 | VSB | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.443 | |
| 3zcw | 4A2 | Kinesin-like protein KIF11 | / | 0.443 | |
| 4bbe | 3O4 | Tyrosine-protein kinase JAK2 | / | 0.443 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.443 | |
| 4elf | 35I | Dihydrofolate reductase | / | 0.443 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.443 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.443 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.443 | |
| 4kba | 1QM | Casein kinase I isoform delta | 2.7.11.1 | 0.443 | |
| 4mxe | ACO | N-acetyltransferase ESCO1 | 2.3.1 | 0.443 | |
| 4uz6 | SCR | Palmitoleoyl-protein carboxylesterase NOTUM | / | 0.443 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.442 | |
| 1dj3 | GDP | Adenylosuccinate synthetase, chloroplastic | / | 0.442 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.442 | |
| 1fm9 | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 1jx0 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.442 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.442 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1wuu | ANP | Galactokinase | 2.7.1.6 | 0.442 | |
| 2gn9 | UPG | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.442 | |
| 2h96 | 893 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.442 | |
| 2p15 | EZT | Estrogen receptor | / | 0.442 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.442 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.442 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2wpw | ACO | Orf14 | / | 0.442 | |
| 3frd | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3gc8 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.442 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.442 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.442 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.442 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.442 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.442 | |
| 3ua5 | 06X | Cytochrome P450 2B6 | 1.14.13 | 0.442 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.442 | |
| 4l45 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.442 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.442 | |
| 4qbj | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.442 | |
| 4ww4 | ADP | RuvB-like helicase | / | 0.442 | |
| 4x81 | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.442 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.442 | |
| 4z9g | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.442 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2b01 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.441 | |
| 2b1p | AIZ | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.441 | |
| 2exc | JNK | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.441 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.441 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.441 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2vcx | D26 | Hematopoietic prostaglandin D synthase | / | 0.441 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.441 | |
| 2y30 | SM8 | Putative repressor SimReg2 | / | 0.441 | |
| 2y8q | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.441 | |
| 3k5u | PFQ | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.441 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.441 | |
| 3tgu | WF3 | Cytochrome b | / | 0.441 | |
| 3wiy | LC6 | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.441 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 4dm6 | TTB | Retinoic acid receptor beta | / | 0.441 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.441 | |
| 4j4b | NAI | Uncharacterized protein | / | 0.441 | |
| 4kwi | 1TJ | Reductase homolog | / | 0.441 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.441 | |
| 4v26 | TF3 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.441 | |
| 5drd | ATP | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 1kqg | HQO | Formate dehydrogenase, nitrate-inducible, cytochrome b556(Fdn) subunit | / | 0.440 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.440 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.440 | |
| 1olm | VTQ | SEC14-like protein 2 | / | 0.440 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.440 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.440 | |
| 1x8v | ESL | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.440 | |
| 2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2j7t | 274 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.440 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 2y3r | TIR | TamL | / | 0.440 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.440 | |
| 3da2 | 4MD | Carbonic anhydrase 13 | 4.2.1.1 | 0.440 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.440 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.440 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3stu | DK3 | Methylketone synthase I | / | 0.440 | |
| 3vso | EK1 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.440 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.440 | |
| 3w2s | W2R | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4elb | 34S | Dihydrofolate reductase | / | 0.440 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.440 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.440 | |
| 4lch | 1WN | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.440 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.440 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.440 | |
| 4mr6 | 1K0 | Bromodomain-containing protein 2 | / | 0.440 | |
| 4nxw | ADP | Mitochondrial dynamics protein MID51 | / | 0.440 | |
| 4xey | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.440 | |
| 5iqh | GNP | Bifunctional AAC/APH | 2.3.1 | 0.440 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.440 |