sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3pfi | ADP | Holliday junction ATP-dependent DNA helicase RuvB |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3pfi | ADP | Holliday junction ATP-dependent DNA helicase RuvB | / | 1.000 | |
| 1w5s | ADP | ORC1-type DNA replication protein 2 | / | 0.539 | |
| 2ql6 | ADP | Nicotinamide riboside kinase 1 | / | 0.514 | |
| 3w8r | ACP | Uridine kinase | / | 0.483 | |
| 4ev0 | CMP | Cyclic AMP receptor protein | / | 0.470 | |
| 1w5t | ADP | ORC1-type DNA replication protein 2 | / | 0.464 | |
| 1n2g | APC | Pantothenate synthetase | 6.3.2.1 | 0.460 | |
| 4jsy | GTP | Metallophosphoesterase | / | 0.458 | |
| 3tqc | ADP | Pantothenate kinase | / | 0.448 | |
| 3spt | UD1 | Bifunctional protein GlmU | / | 0.447 | |
| 5ayz | NCN | Nicotinate-nucleotide pyrophosphorylase [carboxylating] | 2.4.2.19 | 0.447 | |
| 2yw2 | ATP | Phosphoribosylamine--glycine ligase | / | 0.445 | |
| 4mkh | AP5 | Adenylate kinase | / | 0.445 | |
| 2r7p | ANP | Non-structural protein 2 | 3.6.4 | 0.442 | |
| 4m2a | UPG | UDP-glucose pyrophosphorylase | / | 0.441 | |
| 1pf9 | ADP | 60 kDa chaperonin | / | 0.440 |