sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 1.000 | |
| 3mb7 | 14I | Casein kinase II subunit alpha | 2.7.11.1 | 0.598 | |
| 3pe1 | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.569 | |
| 3r0t | FU9 | Casein kinase II subunit alpha | 2.7.11.1 | 0.550 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.539 | |
| 3q9x | EMO | Casein kinase II subunit alpha | 2.7.11.1 | 0.538 | |
| 3ofm | 4B0 | Casein kinase II subunit alpha' | 2.7.11.1 | 0.533 | |
| 4mq1 | 2C3 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.524 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.519 | |
| 3u4u | LNH | Casein kinase II subunit alpha | 2.7.11.1 | 0.515 | |
| 5cvf | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.514 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.512 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.510 | |
| 3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.507 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.504 | |
| 2fvd | LIA | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.502 | |
| 2pvl | P55 | Casein kinase II subunit alpha | 2.7.11.1 | 0.500 | |
| 3mb6 | 01I | Casein kinase II subunit alpha | 2.7.11.1 | 0.500 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.499 | |
| 3be9 | P04 | Casein kinase II subunit alpha | 2.7.11.1 | 0.499 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.498 | |
| 4ix6 | ADP | Uncharacterized protein | / | 0.498 | |
| 2pvm | P29 | Casein kinase II subunit alpha | 2.7.11.1 | 0.495 | |
| 1m2p | HNA | Casein kinase II subunit alpha | 2.7.11.1 | 0.492 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.492 | |
| 4grb | 0XG | Casein kinase II subunit alpha | 2.7.11.1 | 0.492 | |
| 5csh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.492 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.489 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.488 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.487 | |
| 4dgn | LU2 | Casein kinase II subunit alpha | 2.7.11.1 | 0.487 | |
| 2vv9 | IM9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.486 | |
| 5cu6 | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.485 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.483 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.482 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.482 | |
| 4bl1 | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.482 | |
| 5av2 | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.481 | |
| 2pvh | P19 | Casein kinase II subunit alpha | 2.7.11.1 | 0.480 | |
| 3qxp | X64 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.480 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.480 | |
| 1gqt | ACP | Ribokinase | / | 0.479 | |
| 3rkb | 12Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.478 | |
| 4fkw | 62K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.478 | |
| 4gub | 0Y4 | Casein kinase II subunit alpha | 2.7.11.1 | 0.478 | |
| 3rak | 03Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.477 | |
| 5av3 | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.477 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.476 | |
| 2vu3 | LZE | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.476 | |
| 3mfs | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.476 | |
| 4fkv | 61K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.476 | |
| 4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.475 | |
| 4l7s | G7K | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.475 | |
| 5cvh | ADP | Casein kinase II subunit alpha | 2.7.11.1 | 0.475 | |
| 1j1c | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.474 | |
| 2bhe | BRY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.474 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.474 | |
| 4anm | WUL | Casein kinase II subunit alpha | 2.7.11.1 | 0.474 | |
| 4q5h | ANP | Protein kinase OspG | 2.7 | 0.474 | |
| 2i40 | BLZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.473 | |
| 3sm2 | 478 | Putative gag-pro-pol polyprotein | / | 0.473 | |
| 4agu | D15 | Cyclin-dependent kinase-like 1 | / | 0.473 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.473 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.473 | |
| 1lp4 | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.472 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.472 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.472 | |
| 3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.472 | |
| 3rni | 21Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.472 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.472 | |
| 3wow | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.472 | |
| 4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.472 | |
| 4k1b | 1OC | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.472 | |
| 1fvv | 107 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.471 | |
| 1pnv | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.471 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.471 | |
| 2w05 | FRT | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.471 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.471 | |
| 3sw7 | 19K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.471 | |
| 1wvy | STU | Death-associated protein kinase 1 | 2.7.11.1 | 0.470 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.470 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.470 | |
| 1nxk | STU | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.469 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.469 | |
| 2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.469 | |
| 3bqr | 4RB | Death-associated protein kinase 3 | / | 0.469 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.469 | |
| 3owk | 18E | Casein kinase II subunit alpha | 2.7.11.1 | 0.469 | |
| 4dgo | 0JW | Casein kinase II subunit alpha | 2.7.11.1 | 0.469 | |
| 4fv3 | EK6 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.468 | |
| 4ix5 | ANP | Uncharacterized protein | / | 0.468 | |
| 4jqe | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.468 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.467 | |
| 2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 3at3 | ATK | Casein kinase II subunit alpha | 2.7.11.1 | 0.467 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.467 | |
| 3q9w | EMO | Casein kinase II subunit alpha | 2.7.11.1 | 0.467 | |
| 4fx3 | 60K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 4lfi | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.467 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.466 | |
| 1m2q | MNX | Casein kinase II subunit alpha | 2.7.11.1 | 0.466 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.466 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.466 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.466 | |
| 4btj | ATP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.466 | |
| 4eok | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
| 4ez5 | 0RS | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.466 | |
| 4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.466 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.466 | |
| 1aq1 | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 1gih | 1PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.465 | |
| 1zys | 199 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.465 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.465 | |
| 4bch | T7Z | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.465 | |
| 4bcm | T7Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.465 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.465 | |
| 1q41 | IXM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.464 | |
| 2pe1 | 517 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.464 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.464 | |
| 4fks | 46K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.464 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.463 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.463 | |
| 2uzb | C75 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 4ek8 | 16K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.462 | |
| 2a5u | QYT | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.462 | |
| 2cgu | 3A3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.462 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.462 | |
| 3nsz | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.462 | |
| 3qqk | X02 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 3qu0 | X40 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
| 4bgh | 3I6 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
| 4yzc | STU | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.462 | |
| 1daw | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.461 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.461 | |
| 2xch | CKG | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.461 | |
| 3owj | 1EL | Casein kinase II subunit alpha | 2.7.11.1 | 0.461 | |
| 3pj8 | 404 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 3rk5 | 07Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 3rmf | 20Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 3zep | 1NX | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.461 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.461 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.461 | |
| 5e8y | STU | TGF-beta receptor type-2 | 2.7.11.30 | 0.461 | |
| 1nvr | STU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 1pkd | UCN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 1pxp | CK8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 3amb | VX6 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.460 | |
| 3lfq | A28 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.460 | |
| 3rk7 | 08Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 3s1h | 56Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 3sw4 | 18K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 4j95 | ACP | Fibroblast growth factor receptor 2 | / | 0.460 | |
| 3igo | ANP | Calmodulin-domain protein kinase 1, putative | / | 0.459 | |
| 3lfn | A27 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 3zc6 | VFC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.459 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 4mvf | STU | Calcium-dependent protein kinase 2 | 2.7.11.1 | 0.459 | |
| 5dr6 | SKE | Aurora kinase A | 2.7.11.1 | 0.459 | |
| 2obj | VRV | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.458 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.458 | |
| 2w17 | I19 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 3ral | 04Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 4btj | ADP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.458 | |
| 4fko | 20K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 4hvi | 19S | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.458 | |
| 4im2 | BX7 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.458 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.458 | |
| 1day | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 1xjd | STU | Protein kinase C theta type | 2.7.11.13 | 0.457 | |
| 2r3j | SCJ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 3lpb | NVB | Tyrosine-protein kinase JAK2 | / | 0.457 | |
| 3qtu | X44 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.457 | |
| 5aux | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.457 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 2pe2 | 464 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.456 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.456 | |
| 2yaa | ATP | Death-associated protein kinase 2 | / | 0.456 | |
| 2zdu | 446 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.456 | |
| 3ckx | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.456 | |
| 3nbv | ANP | Ketohexokinase | / | 0.456 | |
| 3rpv | 26Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 3rvg | 17P | Tyrosine-protein kinase JAK2 | / | 0.456 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.456 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.456 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 1g5s | I17 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 3kn5 | ANP | Ribosomal protein S6 kinase alpha-5 | 2.7.11.1 | 0.455 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.455 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.455 | |
| 3s2p | PMU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 3sqq | 99Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 3zdu | 38R | Cyclin-dependent kinase-like 3 | 2.7.11.22 | 0.455 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 4acm | 7YG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 4fsz | HK8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.454 | |
| 1nyx | DRF | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.454 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.454 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.454 | |
| 2vn9 | GVD | Calcium/calmodulin-dependent protein kinase type II subunit delta | 2.7.11.17 | 0.454 | |
| 2vtq | LZA | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 3akm | 11D | Fatty acid-binding protein, intestinal | / | 0.454 | |
| 3orm | AGS | Serine/threonine protein kinase | / | 0.454 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.453 | |
| 1pxm | CK5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 1q3d | STU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.453 | |
| 1tqp | ATP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.453 | |
| 2b52 | D42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.453 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.453 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.453 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.453 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.453 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.453 | |
| 3kkv | B99 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.453 | |
| 3lki | ATP | Fructokinase | / | 0.453 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 3my5 | RFZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 3r7y | Z04 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 3v5l | 0G1 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.453 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.453 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.453 | |
| 4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.453 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.453 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 1ykr | 628 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 2pvj | P44 | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 3kvx | FMY | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.452 | |
| 3r9h | Z67 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3t8v | BTJ | M1 family aminopeptidase | 3.4.11 | 0.452 | |
| 3tnw | F18 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.452 | |
| 4fsn | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 4ful | 0VU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.452 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.452 | |
| 1ydr | IQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 1yvj | 4ST | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.451 | |
| 2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.451 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2wih | P48 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.451 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.451 | |
| 4bie | IE6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.451 | |
| 4fkr | 45K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 4ft5 | H2K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.451 | |
| 2cke | IQU | Death-associated protein kinase 2 | / | 0.450 | |
| 3qcy | 3Q3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.450 | |
| 4eor | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 5auv | AGI | Death-associated protein kinase 1 | 2.7.11.1 | 0.450 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2f7e | 2EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.449 | |
| 3qtx | X43 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3zdf | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.449 | |
| 4eol | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 4otp | ADP | Serine/threonine-protein kinase RIO1 | 2.7.11.1 | 0.449 | |
| 4rqv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 1q3w | ATU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.448 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.448 | |
| 2xbj | XBJ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.448 | |
| 3d7t | STU | Tyrosine-protein kinase CSK | / | 0.448 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.448 | |
| 3nun | JMZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.448 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 4eut | BX7 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.448 | |
| 4ijp | 1EH | Serine/threonine-protein kinase PRP4 homolog | 2.7.11.1 | 0.448 | |
| 4pd6 | URI | Nucleoside permease | / | 0.448 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.448 | |
| 1h0w | 207 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.447 | |
| 2ad5 | ADP | CTP synthase | / | 0.447 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 3ddq | RRC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.447 | |
| 3l1s | Z92 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.447 | |
| 3lfs | A07 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3nux | 3NV | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.447 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.447 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 4fa6 | 0TA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4jik | 1KO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 1om1 | IQA | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 2b55 | D31 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 2br1 | PFP | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.446 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.446 | |
| 3gu7 | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.446 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3r8l | Z30 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.446 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 4mf1 | 29Y | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.446 | |
| 4ock | ANP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.446 | |
| 5dp2 | NAP | CurF | / | 0.446 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 1e81 | M91 | Endothiapepsin | 3.4.23.22 | 0.445 | |
| 1e9h | INR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 1oir | HDY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3b9l | AZZ | Serum albumin | / | 0.445 | |
| 3i60 | E86 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.445 | |
| 3nyn | SGV | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.445 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.445 | |
| 4dfn | 0K1 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.445 | |
| 4enx | Z20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 4erw | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.445 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.445 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.445 | |
| 5auz | GEN | Death-associated protein kinase 1 | 2.7.11.1 | 0.445 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.444 | |
| 1ppm | 0P1 | Penicillopepsin-1 | 3.4.23.20 | 0.444 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.444 | |
| 2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2oiq | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.444 | |
| 3gu6 | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.444 | |
| 3llt | ANP | Protein serine/threonine kinase-1 | / | 0.444 | |
| 3qru | X19 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
| 4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.444 | |
| 4ux9 | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.444 | |
| 1mru | AGS | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.443 | |
| 1p2a | 5BN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 1w0x | OLO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 2h96 | 893 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.443 | |
| 2pmo | HMD | Protein kinase 7 | / | 0.443 | |
| 3beg | ANP | SRSF protein kinase 1 | 2.7.11.1 | 0.443 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.443 | |
| 3qtz | X42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.443 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4ask | K0I | Lysine-specific demethylase 6B | 1.14.11 | 0.443 | |
| 4cki | ADN | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.443 | |
| 4fg9 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.443 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.443 | |
| 5f54 | TMP | Single-stranded-DNA-specific exonuclease | / | 0.443 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 1z5m | LI8 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.442 | |
| 2exc | JNK | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.442 | |
| 2xvw | 9NR | Serum albumin | / | 0.442 | |
| 3a62 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.442 | |
| 3ezr | EZR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.442 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.442 | |
| 3rk9 | 09Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3t8o | ATP | Rhodopsin kinase | / | 0.442 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 5auw | QUE | Death-associated protein kinase 1 | 2.7.11.1 | 0.442 | |
| 1pxl | CK4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 1tqm | ANP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.441 | |
| 1zdw | FLV | Prenyltransferase | / | 0.441 | |
| 2pzi | AXX | Serine/threonine-protein kinase PknG | 2.7.11.1 | 0.441 | |
| 2wti | WTI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.441 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.441 | |
| 3ddp | RC8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3qcq | 3Q0 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 4ekl | 0RF | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.441 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 4hgt | 15G | Casein kinase I isoform delta | 2.7.11.1 | 0.441 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.440 | |
| 1h1s | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1m2r | MNY | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 1q8u | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 2r5t | ANP | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.440 | |
| 2wtd | ZZK | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.440 | |
| 2xrw | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.440 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.440 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.440 | |
| 4dta | ADN | APH(2'')-Id | / | 0.440 | |
| 4f08 | 1RS | Tyrosine-protein kinase JAK2 | / | 0.440 | |
| 4fg8 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.440 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.440 | |
| 4i0s | 1B5 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.440 | |
| 4jr7 | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 4k33 | ACP | Fibroblast growth factor receptor 3 | 2.7.10.1 | 0.440 | |
| 4mq2 | 2C4 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.440 | |
| 4o0w | ADN | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 4oau | ADP | 2-5A-dependent ribonuclease | 3.1.26 | 0.440 |