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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3pd4A3GThreonine--tRNA ligase6.1.1.3

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3pd4A3GThreonine--tRNA ligase6.1.1.31.000
3pd2A3SThreonine--tRNA ligase6.1.1.30.620
2hl2SSAThreonine--tRNA ligase6.1.1.30.586
4rr6A3SProbable threonine--tRNA ligase 26.1.1.30.582
4rrrA3TThreonine--tRNA ligase6.1.1.30.580
4rriA3TProbable threonine--tRNA ligase 26.1.1.30.569
3pd5TSBThreonine--tRNA ligase6.1.1.30.564
4rrgA3TThreonine--tRNA ligase6.1.1.30.564
3pd3A3TThreonine--tRNA ligase6.1.1.30.560
4rrfA3SThreonine--tRNA ligase6.1.1.30.560
4rrhA3SProbable threonine--tRNA ligase 26.1.1.30.554
4rr8A3SProbable threonine--tRNA ligase 26.1.1.30.553
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.549
2hl1A3SThreonine--tRNA ligase6.1.1.30.545
4rrqA3SThreonine--tRNA ligase6.1.1.30.544
4rrmA3TProbable threonine--tRNA ligase 26.1.1.30.542
4rraA3TProbable threonine--tRNA ligase 26.1.1.30.531
4rrbA3TProbable threonine--tRNA ligase 26.1.1.30.528
4rrcA3TProbable threonine--tRNA ligase 26.1.1.30.527
4rrdA3TProbable threonine--tRNA ligase 26.1.1.30.519
2hl0A3SThreonine--tRNA ligase6.1.1.30.514
4rr9A3SProbable threonine--tRNA ligase 26.1.1.30.514
4rrlA3SProbable threonine--tRNA ligase 26.1.1.30.505
1bwsNDPGDP-L-fucose synthase/0.502
3a783EVVitamin D3 receptor/0.502
4rrkA3TProbable threonine--tRNA ligase 26.1.1.30.495
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.494
3vt7VDXVitamin D3 receptor/0.492
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.492
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.490
3vt9YI4Vitamin D3 receptor/0.488
1cqp803Integrin alpha-L/0.487
4ockANPN-acetylhexosamine 1-kinase2.7.1.1620.486
3gwfNAPCyclohexanone monooxygenase/0.485
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.484
1r2jFADFkbI/0.484
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.482
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.482
4a8v2ANMajor pollen allergen Bet v 1-J/0.482
4dpuAGSMevalonate diphosphate decarboxylase/0.482
3q43D66M1 family aminopeptidase3.4.110.480
4mv8ACPBiotin carboxylase6.3.4.140.480
4xiwAZMCarbonic anhydrase, alpha type/0.480
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.479
3h3t16HCollagen type IV alpha-3-binding protein/0.478
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.477
1dr3HBIDihydrofolate reductase1.5.1.30.476
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.476
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.476
3gfbNADL-threonine 3-dehydrogenase/0.476
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.475
2z0ySAMRibosomal RNA small subunit methyltransferase E/0.475
1xddAAYIntegrin alpha-L/0.474
2ikuLIYRenin3.4.23.150.474
2vnhFADNADPH:ferredoxin reductase/0.474
1vyrFMNPentaerythritol tetranitrate reductase/0.473
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.473
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.473
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.472
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.472
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.472
2abi1CAMineralocorticoid receptor/0.472
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.472
2jlcTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.472
4a862ANMajor pollen allergen Bet v 1-A/0.472
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.472
1jpaANPEphrin type-B receptor 22.7.10.10.471
2w1fL0FAurora kinase A2.7.11.10.471
4lfiGNPCasein kinase II subunit alpha2.7.11.10.471
4s0vSUVOrexin receptor type 2/0.471
4bgg844Activin receptor type-12.7.11.300.470
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.470
4in44IDKelch-like ECH-associated protein 1/0.470
4rnuFMNNADPH dehydrogenase 11.6.99.10.470
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.470
1oyaFMNNADPH dehydrogenase 11.6.99.10.469
1h51FMNPentaerythritol tetranitrate reductase/0.468
3u8hBHPPhospholipase A2, membrane associated/0.468
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.468
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.467
1hvyD16Thymidylate synthase2.1.1.450.467
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.467
2lbaCHOFatty acid binding protein 6/0.467
3p8iFMNPentaerythritol tetranitrate reductase/0.467
3u9eCOALmo1369 protein/0.467
4xymCOAAcyl-CoA synthetase (NDP forming)/0.467
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.466
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
3zhtTD9Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.466
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.466
3pwhZMAAdenosine receptor A2a/0.466
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.465
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
4a83DXCMajor pollen allergen Bet v 1-A/0.465
4ejmNAPPutative zinc-binding dehydrogenase/0.465
1bwkFMNNADPH dehydrogenase 11.6.99.10.464
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.464
1ia3TQ5Dihydrofolate reductase1.5.1.30.464
1icpFMN12-oxophytodienoate reductase 11.3.1.420.464
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.464
2bxmIMNSerum albumin/0.464
3f03FMNPentaerythritol tetranitrate reductase/0.464
3fr5I4AFatty acid-binding protein, adipocyte/0.464
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.464
5h8tRTLRetinol-binding protein 1/0.464
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.463
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.463
3q44D50M1 family aminopeptidase3.4.110.463
3qt62P0Mevalonate diphosphate decarboxylase/0.463
3s1dZIRCytokinin dehydrogenase 11.5.99.120.463
4ryvZEAProtein LlR18A/0.463
1crbRTLRetinol-binding protein 1/0.462
1lp4ANPCasein kinase II subunit alpha2.7.11.10.462
2zbaZBATrichothecene 3-O-acetyltransferase/0.462
3ibqATPPyridoxal kinase/0.462
3zoiM2WIsopenicillin N synthase1.21.3.10.462
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.462
1rx8FOLDihydrofolate reductase1.5.1.30.461
1uy8PU5Heat shock protein HSP 90-alpha/0.461
2cx8SAHRibosomal RNA small subunit methyltransferase E/0.461
3gl2D3MDdmC/0.461
3sh25DRDihydrofolate reductase1.5.1.30.461
3zeiAWHO-acetylserine sulfhydrylase/0.461
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
4i6gFADCryptochrome-2/0.461
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.460
2c31TZDOxalyl-CoA decarboxylase4.1.1.80.460
2e9dB76Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.460
2xc3RT8Steroid C26-monooxygenase1.14.13.1410.460
3h3qH13Collagen type IV alpha-3-binding protein/0.460
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.460
3nr4PYVAbscisic acid receptor PYL2/0.460
3p84FMNPentaerythritol tetranitrate reductase/0.460
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.460
4gk3L87Ephrin type-A receptor 32.7.10.10.460
4y8wSTRSteroid 21-hydroxylase/0.460
1hquHBYGag-Pol polyprotein2.7.7.490.459
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.459
1qrpHH0Pepsin A-43.4.23.10.459
1s5kCOAAminoglycoside N(6')-acetyltransferase type 1/0.459
1t7o152Carnitine O-acetyltransferase2.3.1.70.459
1v35NAIEnoyl-ACP reductase/0.459
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.459
2g1s4IGRenin3.4.23.150.459
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.459
4la7A1OAbscisic acid receptor PYL2/0.459
1t87CAMCamphor 5-monooxygenase1.14.15.10.458
1y4lSVRBasic phospholipase A2 homolog 2/0.458
2d8aNADL-threonine 3-dehydrogenase/0.458
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.458
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.458
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
3jpuTY4Transcriptional activator protein LasR/0.458
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
3tnlNADShikimate dehydrogenase (NADP(+))/0.458
3w78CBDFMN-dependent NADH-azoreductase/0.458
4jbsP52Endoplasmic reticulum aminopeptidase 23.4.110.458
4l0qNADAlcohol dehydrogenase class-3/0.458
4mwhATPCasein kinase II subunit alpha2.7.11.10.458
4n57ADPAPH(2'')-Id/0.458
4x5gFOLDihydrofolate reductase1.5.1.30.458
4yqfGDPSeptin-9/0.458
1bwlFMNNADPH dehydrogenase 11.6.99.10.457
1m13HYFNuclear receptor subfamily 1 group I member 2/0.457
1synF89Thymidylate synthase/0.457
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.457
2ejzSAHDiphthine synthase/0.457
2iko7IGRenin3.4.23.150.457
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.457
2rhrEMOPutative ketoacyl reductase1.3.10.457
2w9hTOPDihydrofolate reductase1.5.1.30.457
3l63CAMCamphor 5-monooxygenase1.14.15.10.457
3lnbCOAN-acetyltransferase family protein/0.457
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.457
3zhrTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.457
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.457
4cd2FOLDihydrofolate reductase1.5.1.30.457
4cukNAID-lactate dehydrogenase/0.457
4cztCPSCBL-interacting serine/threonine-protein kinase 232.7.11.10.457
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.457
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.457
5ejaTD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.457
1bsvNDPGDP-L-fucose synthase/0.456
1cx2S58Prostaglandin G/H synthase 21.14.99.10.456
1xowR18Androgen receptor/0.456
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.456
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.456
2qbmCAMCamphor 5-monooxygenase1.14.15.10.456
3fwiCAMCamphor 5-monooxygenase1.14.15.10.456
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.456
3invC50Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.456
3own3OWRenin3.4.23.150.456
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
4dymIYZActivin receptor type-12.7.11.300.456
4ead0NPThymidine phosphorylase2.4.2.40.456
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.456
4h6rFDAProline dehydrogenase/0.456
4qzuRTLRetinol-binding protein 2/0.456
1f5fDHTSex hormone-binding globulin/0.455
1jg0DDTThymidylate synthase/0.455
1ppjANYCytochrome b/0.455
1uy6PU3Heat shock protein HSP 90-alpha/0.455
1zprCB3Thymidylate synthase/0.455
2a1nCAMCamphor 5-monooxygenase1.14.15.10.455
2nmtNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.455
2qo9ANPEphrin type-A receptor 32.7.10.10.455
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.455
3jwcEKBDihydrofolate reductase/0.455
3ojiPYVAbscisic acid receptor PYL3/0.455
3oqfS51Renin3.4.23.150.455
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.455
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.455
4fi1ATPCasein kinase II subunit alpha2.7.11.10.455
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
4klaCHDFerrochelatase, mitochondrial4.99.1.10.455
4l6gCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.455
4r21STRCytochrome P450 family 17 polypeptide 2/0.455
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.455
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.455
1dz6CAMCamphor 5-monooxygenase1.14.15.10.454
1t88CAMCamphor 5-monooxygenase1.14.15.10.454
2iviACWIsopenicillin N synthase1.21.3.10.454
2vbdV10Isopenicillin N synthase1.21.3.10.454
2y8lADP5'-AMP-activated protein kinase subunit gamma-1/0.454
3bw4FMNPutative 2-nitropropane dioxygenase/0.454
3c3xNAPEugenol synthase 11.1.1.3180.454
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3jzfJZKBiotin carboxylase6.3.4.140.454
3lq2TDPPyruvate dehydrogenase E1 component1.2.4.10.454
3oqkS52Renin3.4.23.150.454
3p3zP3ZPutative cytochrome P450/0.454
3p8jFMNPentaerythritol tetranitrate reductase/0.454
3pe6ZYHMonoglyceride lipase/0.454
3q9zTXQCasein kinase II subunit alpha2.7.11.10.454
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.454
3zlx5EZDual specificity mitogen-activated protein kinase kinase 12.7.12.20.454
4cdmFO1Deoxyribodipyrimidine photolyase/0.454
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
4g3jVNTLanosterol 14-alpha-demethylase/0.454
4tmcFMNOld yellow enzyme/0.454
5cvhADPCasein kinase II subunit alpha2.7.11.10.454
1bk0ACVIsopenicillin N synthase1.21.3.10.453
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.453
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.453
1rsgFADPolyamine oxidase FMS1/0.453
1yw2PGJMitogen-activated protein kinase 14/0.453
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
2g1n1IGRenin3.4.23.150.453
2i4qUA4Renin3.4.23.150.453
2q9fC3SCholesterol 24-hydroxylase/0.453
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.453
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
2z9dFMNFMN-dependent NADH-azoreductase/0.453
3c15FOKAdenylate cyclase type 2/0.453
3c15FOKAdenylate cyclase type 5/0.453
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.453
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.453
4df2FMNNADPH dehydrogenase/0.453
4g2fC07Ephrin type-A receptor 32.7.10.10.453
4h6kFMNNADPH dehydrogenase 11.6.99.10.453
4m6p20RNicotinamide phosphoribosyltransferase2.4.2.120.453
4q4kFMNUncharacterized protein/0.453
5cccDDFDihydrofolate reductase1.5.1.30.453
1dhjMTXDihydrofolate reductase1.5.1.30.452
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.452
2y3rTIRTamL/0.452
3ar5TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.452
3be9P04Casein kinase II subunit alpha2.7.11.10.452
3gwfFADCyclohexanone monooxygenase/0.452
3ix3OHNTranscriptional activator protein LasR/0.452
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3kpzZNEVitamin D3 receptor/0.452
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.452
4b8zNAPGDP-L-fucose synthase1.1.1.2710.452
4dfrMTXDihydrofolate reductase1.5.1.30.452
4fgh0U6Dihydrofolate reductase1.5.1.30.452
4ia7BIVVitamin D3 receptor A/0.452
4ipw1G7Mycocyclosin synthase1.14.21.90.452
4kwhNAPReductase homolog/0.452
4lsjLSJGlucocorticoid receptor/0.452
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.452
1rfuADPPyridoxal kinase2.7.1.350.451
1rfvADPPyridoxal kinase2.7.1.350.451
1s3yTQTDihydrofolate reductase1.5.1.30.451
2hmaSAMtRNA-specific 2-thiouridylase MnmA/0.451
2hs8FMN12-oxophytodienoate reductase 31.3.1.420.451
2huxSAHDiphthine synthase/0.451
2qblCAMCamphor 5-monooxygenase1.14.15.10.451
2uxoTACHTH-type transcriptional regulator TtgR/0.451
3b9lAZZSerum albumin/0.451
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3eyhIZATyrosine-protein kinase JAK1/0.451
3gw9VNILanosterol 14-alpha-demethylase/0.451
3ielU5PRibonuclease TTHA02523.10.451
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.451
3rmf20ZCyclin-dependent kinase 22.7.11.220.451
3wrjCAMCamphor 5-monooxygenase1.14.15.10.451
4dgmAGICasein kinase II subunit alpha2.7.11.10.451
4i1nFOLDihydrofolate reductase1.5.1.30.451
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.451
4ly91YYGlucokinase regulatory protein/0.451
4rrjA3SProbable threonine--tRNA ligase 26.1.1.30.451
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.451
4v12POGMaoC like domain protein/0.451
4y3zF41Endothiapepsin3.4.23.220.451
5im3DTPRibonucleoside-diphosphate reductase/0.451
5kgpACOPredicted acetyltransferase/0.451
1pkfEPDEpothilone C/D epoxidase1.140.450
1y0s331Peroxisome proliferator-activated receptor delta/0.450
2a5kAZPReplicase polyprotein 1ab3.4.220.450
2abbFMNPentaerythritol tetranitrate reductase/0.450
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.450
2p5uNADUDP-glucose 4-epimerase/0.450
2qimZEAClass 10 plant pathogenesis-related protein/0.450
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.450
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
3bw2FMNPutative 2-nitropropane dioxygenase/0.450
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.450
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.450
3fwjCAMCamphor 5-monooxygenase1.14.15.10.450
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.450
3hgoFMN12-oxophytodienoate reductase 31.3.1.420.450
3l0lHC3Nuclear receptor ROR-gamma/0.450
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.450
3mtfA3FActivin receptor type-12.7.11.300.450
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.450
4m9aFDAAcyl-CoA dehydrogenase/0.450
4mlp2CXCryptochrome-2/0.450
4xz3COAAcyl-CoA synthetase (NDP forming)/0.450
1dr2TAPDihydrofolate reductase1.5.1.30.449
1e7qNAPGDP-L-fucose synthase/0.449
1h63FMNPentaerythritol tetranitrate reductase/0.449
1hb1OCVIsopenicillin N synthase1.21.3.10.449
1qxoFMNChorismate synthase/0.449
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.449
1udaUFGUDP-glucose 4-epimerase5.1.3.20.449
2a3iC0RMineralocorticoid receptor/0.449
2bpw1INGag-Pol polyprotein3.4.23.160.449
2ejvNADL-threonine 3-dehydrogenase/0.449
2hcdBIVVitamin D3 receptor A/0.449
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.449
2wihP48Cyclin-dependent kinase 22.7.11.220.449
2x7gPVBSRSF protein kinase 22.7.11.10.449
2y8qADP5'-AMP-activated protein kinase subunit gamma-1/0.449
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.449
3r34COA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.449
4a6cQG9Gag-Pol polyprotein3.4.23.160.449
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.449
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.449
4xivACPChemotaxis protein CheA2.7.13.30.449
1cjkFOKAdenylate cyclase type 2/0.448
1cjkFOKAdenylate cyclase type 5/0.448
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.448
1vrwNAIEnoyl-ACP reductase/0.448
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.448
2dvlFADAcyl-CoA dehydrogenase/0.448
2feuCAMCamphor 5-monooxygenase1.14.15.10.448
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
2po7CHDFerrochelatase, mitochondrial4.99.1.10.448
3bhtMFRCyclin-dependent kinase 22.7.11.220.448
3d8vUD1Bifunctional protein GlmU/0.448
3enkUPGUDP-glucose 4-epimerase/0.448
3fwgCAMCamphor 5-monooxygenase1.14.15.10.448
3imeBZ2Pantothenate synthetase6.3.2.10.448
3pqbVGPPutative oxidoreductase/0.448
3tdaPN0Cytochrome P450 2D6/0.448
3vt8YI3Vitamin D3 receptor/0.448
4a81DXCMajor pollen allergen Bet v 1-A/0.448
4gi2NAPCrotonyl-CoA carboxylase/reductase/0.448
4i8vBHFCytochrome P450 1A11.14.14.10.448
5aluHD2Bifunctional epoxide hydrolase 23.1.3.760.448
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.447
1q45FMN12-oxophytodienoate reductase 31.3.1.420.447
1t2bCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.447
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.447
2vbpVB1Isopenicillin N synthase1.21.3.10.447
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.447
2y60M8FIsopenicillin N synthase1.21.3.10.447
2zdt46CMitogen-activated protein kinase 102.7.11.240.447
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.447
3ddw055Glycogen phosphorylase, liver form2.4.1.10.447
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.447
3fr8NDPKetol-acid reductoisomerase, chloroplastic1.1.1.860.447
3ijoB4DGlutamate receptor 2/0.447
3maaFKPAdenylate cyclase type 2/0.447
3maaFKPAdenylate cyclase type 5/0.447
3nl6TPSUncharacterized protein/0.447
3uyt0CKCasein kinase I isoform delta2.7.11.10.447
3w0yDS4Vitamin D3 receptor/0.447
4bfvZVVPantothenate kinase2.7.1.330.447
4jia1K3Tyrosine-protein kinase JAK2/0.447
4m4922YL-lactate dehydrogenase A chain1.1.1.270.447
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.447
1cs4FOKAdenylate cyclase type 2/0.446
1cs4FOKAdenylate cyclase type 5/0.446
1ezvUQ6Cytochrome b/0.446
1ikgREXD-alanyl-D-alanine carboxypeptidase3.4.16.40.446
1w6hTITPlasmepsin-23.4.23.390.446
1z6tADPApoptotic protease-activating factor 1/0.446
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.446
2bxqIMNSerum albumin/0.446
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.446
2harOCCVitamin D3 receptor/0.446
2wgjVGHHepatocyte growth factor receptor2.7.10.10.446
2xpc051UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.446
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
3p62FMNPentaerythritol tetranitrate reductase/0.446
3rudNADUDP-N-acetylglucosamine 4-epimerase/0.446
3svj4LIPeptide deformylase/0.446
3vjoANPEpidermal growth factor receptor2.7.10.10.446
3w1tWRODihydroorotate dehydrogenase (fumarate)1.3.98.10.446
3wqmB29Diterpene synthase3.1.7.80.446
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4eftEFTHeat shock protein HSP 90-alpha/0.446
4g1z0VPVitamin D3 receptor A/0.446
4gk2L66Ephrin type-A receptor 32.7.10.10.446
4jicFMNGTN Reductase/0.446
4ktc1X3Genome polyprotein3.4.21.980.446
4lt63ATPoly(A) polymerase gamma2.7.7.190.446
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.446
4xguADPPutative pachytene checkpoint protein 2/0.446
4zj8SUVOrexin receptor type 1/0.446
1cjtFOKAdenylate cyclase type 2/0.445
1cjtFOKAdenylate cyclase type 5/0.445
1gpdNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.445
1h50FMNPentaerythritol tetranitrate reductase/0.445
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.445
1likADNAdenosine kinase2.7.1.200.445
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.445
1uyuCAMCamphor 5-monooxygenase1.14.15.10.445
1zeoC01Peroxisome proliferator-activated receptor gamma/0.445
1zrzBI1Protein kinase C iota type2.7.11.130.445
2bktRPFRenin3.4.23.150.445
2ea2F77Methionine aminopeptidase 2/0.445
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.445
2v58LZJBiotin carboxylase6.3.4.140.445
2xvv9DNSerum albumin/0.445
3fwfCAMCamphor 5-monooxygenase1.14.15.10.445
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.445
3imgBZ2Pantothenate synthetase6.3.2.10.445
3oafOAGDihydrofolate reductase1.5.1.30.445
3pe2E1BCasein kinase II subunit alpha2.7.11.10.445
4a802ANMajor pollen allergen Bet v 1-A/0.445
4jazSTLPeroxisome proliferator-activated receptor gamma/0.445
5cb3APRO-acetyl-ADP-ribose deacetylase/0.445
1e3eNAIAlcohol dehydrogenase 41.1.1.10.444
1fmlRTLRetinol dehydratase/0.444
1hb3SCVIsopenicillin N synthase1.21.3.10.444
1hncGDNGlutathione S-transferase Mu 22.5.1.180.444
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1yrdCAMCamphor 5-monooxygenase1.14.15.10.444
1zq5E04Aldo-keto reductase family 1 member C3/0.444
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.444
2cy0NAPShikimate dehydrogenase (NADP(+))/0.444
2gjlFMNNitronate monooxygenase1.13.12.160.444
2jb4A14Isopenicillin N synthase1.21.3.10.444
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.444
3cseN22Uncharacterized protein/0.444
3dafFEG5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.444
3g5hYTTMycocyclosin synthase1.14.21.90.444
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.444
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.444
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
3mqe416Prostaglandin G/H synthase 21.14.99.10.444
3pre3REPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
3vrwYS5Vitamin D3 receptor/0.444
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.444
4a31MYAGlycylpeptide N-tetradecanoyltransferase/0.444
4a6bQG8Gag-Pol polyprotein3.4.23.160.444
4bqrIBHEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.444
4cp4CAMCamphor 5-monooxygenase1.14.15.10.444
4ek1CAMCamphor 5-monooxygenase1.14.15.10.444
4h9tHL4Phosphotriesterase/0.444
4iteTEYVitamin D3 receptor/0.444
4jqeANPCasein kinase II subunit alpha2.7.11.10.444
4kwi1TJReductase homolog/0.444
4o701QKBromodomain-containing protein 4/0.444
4psbGA3Cytokinin-specific binding protein/0.444
4r81FMNPredicted NADH dehydrogenase/0.444
4rnvFMNNADPH dehydrogenase 11.6.99.10.444
4rrxLURProstaglandin G/H synthase 21.14.99.10.444
1dawANPCasein kinase II subunit alpha2.7.11.10.443
1fvv107Cyclin-dependent kinase 22.7.11.220.443
1fxsNAPGDP-L-fucose synthase/0.443
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.443
1oi9N20Cyclin-dependent kinase 22.7.11.220.443
1pnvTYDdTDP-epi-vancosaminyltransferase2.4.1.3110.443
1q4u4CA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.443
1u54ACPActivated CDC42 kinase 1/0.443
1x8lOXRRetinol dehydratase/0.443
2ek3SAHDiphthine synthase/0.443
2fk8SAMHydroxymycolate synthase MmaA42.1.10.443
2g1pSAHDNA adenine methylase2.1.1.720.443
2he5NDPAldo-keto reductase family 1 member C211.1.10.443
2j9lATPH(+)/Cl(-) exchange transporter 5/0.443
2qbnCAMCamphor 5-monooxygenase1.14.15.10.443
2qboCAMCamphor 5-monooxygenase1.14.15.10.443
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.443
2wi72KLHeat shock protein HSP 90-alpha/0.443
3cgfJNFMitogen-activated protein kinase 102.7.11.240.443
3cgtBCDCyclomaltodextrin glucanotransferase2.4.1.190.443
3cukFADD-amino-acid oxidase1.4.3.30.443
3il1B5DGlutamate receptor 2/0.443
3jqpA2PFerredoxin--NADP reductase, apicoplast/0.443
3junAKDPhenazine biosynthesis protein A/B/0.443
3lakKR1Gag-Pol polyprotein2.7.7.490.443
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.443
3sdi3SDProteasome subunit beta type-53.4.25.10.443
3sdi3SDProteasome subunit beta type-63.4.25.10.443
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.443
3wrmCAMCamphor 5-monooxygenase1.14.15.10.443
3zs5SB2Mitogen-activated protein kinase 14/0.443
4alhA9PBromodomain-containing protein 2/0.443
4bfxZVXPantothenate kinase2.7.1.330.443
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4fv7E94Mitogen-activated protein kinase 12.7.11.240.443
4hge15VTyrosine-protein kinase JAK2/0.443
4ia3BIVVitamin D3 receptor A/0.443
4nbiD3YD-tyrosyl-tRNA(Tyr) deacylase/0.443
4uymVOR14-alpha sterol demethylase Cyp51B/0.443
5ej9TPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.443
1bygSTUTyrosine-protein kinase CSK/0.442
1dirNADDihydropteridine reductase1.5.1.340.442
1dyiFOLDihydrofolate reductase1.5.1.30.442
1dz4CAMCamphor 5-monooxygenase1.14.15.10.442
1fm4DXCMajor pollen allergen Bet v 1-L/0.442
1h74AGSHomoserine kinase2.7.1.390.442
1iidNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.442
1kp2ATPArgininosuccinate synthase6.3.4.50.442
1m2pHNACasein kinase II subunit alpha2.7.11.10.442
1q4t4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.442
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.442
2fhnBNIAvidin-related protein 4/5/0.442
2hb7O1CVitamin D3 receptor/0.442
2ibzUQ6Cytochrome b/0.442
2j0lANPFocal adhesion kinase 12.7.10.20.442
2pvkP45Casein kinase II subunit alpha2.7.11.10.442
2w71L23Biotin carboxylase6.3.4.140.442
3cgcCOACoenzyme A disulfide reductase/0.442
3fhxPLPPyridoxal kinase2.7.1.350.442
3ml9ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.442
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.442
3rm618ZCyclin-dependent kinase 22.7.11.220.442
3slkNDPPolyketide synthase extender module 2/0.442
3tjlFMNNADPH dehydrogenase/0.442
3zhsTD6Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.442
4dgnLU2Casein kinase II subunit alpha2.7.11.10.442
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
4g7gVFVLanosterol 14-alpha-demethylase/0.442
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.442
4lcg1WMUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.442
5czySAMEukaryotic huntingtin interacting protein B/0.442
6cp4CAMCamphor 5-monooxygenase1.14.15.10.442
1dliUDXUDP-glucose 6-dehydrogenase/0.441
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.441
1lb9DNQGlutamate receptor 2/0.441
1m2qMNXCasein kinase II subunit alpha2.7.11.10.441
1o76CAMCamphor 5-monooxygenase1.14.15.10.441
1opbRETRetinol-binding protein 2/0.441
1rszDIHPurine nucleoside phosphorylase2.4.2.10.441
1u4dDBQActivated CDC42 kinase 1/0.441
1vkgCRIHistone deacetylase 83.5.1.980.441
1vyw292Cyclin-dependent kinase 22.7.11.220.441
2bu9HFVIsopenicillin N synthase1.21.3.10.441
2fonFADAcyl-coenzyme A oxidase/0.441
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.441
2nn7M29Carbonic anhydrase 14.2.1.10.441
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
2vteIK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.441
2w98P1ZProstaglandin reductase 21.3.1.480.441
2zjwREFCasein kinase II subunit alpha2.7.11.10.441
3bc3OPTCathepsin L13.4.22.150.441
3bgrT27Gag-Pol polyprotein2.7.7.490.441
3cf0ADPTransitional endoplasmic reticulum ATPase3.6.4.60.441
3fp0FP015-O-acetyltransferase/0.441
3ha7B32Hydroxymycolate synthase MmaA42.1.10.441
3hllI45Mitogen-activated protein kinase 14/0.441
3lqfNADGalactitol dehydrogenase/0.441
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.441
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.441
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.441
4ijp1EHSerine/threonine-protein kinase PRP4 homolog2.7.11.10.441
4l4fCAMCamphor 5-monooxygenase1.14.15.10.441
4l4xNDPAmphI/0.441
4lhtCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.441
4ng2OHNTranscriptional activator protein LasR/0.441
4o1mNADEnoyl-acyl carrier reductase/0.441
4ocvANPAminoglycoside phosphotransferase/0.441
4u0mGTPCyclic GMP-AMP synthase/0.441
4xgxADPFAD:protein FMN transferase/0.441
4xivADPChemotaxis protein CheA2.7.13.30.441
5a27MYAGlycylpeptide N-tetradecanoyltransferase/0.441
1e3gR18Androgen receptor/0.440
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.440
1ia4TQ6Dihydrofolate reductase1.5.1.30.440
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.440
2aa3AP0L-lactate dehydrogenase/0.440
2dcnADP2-keto-3-deoxy-gluconate kinase/0.440
2g97DGBNicotinamide phosphoribosyltransferase2.4.2.120.440
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.440
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.440
2j9gANPBiotin carboxylase6.3.4.140.440
2m56CAMCamphor 5-monooxygenase1.14.15.10.440
2nr4FMNConserved protein/0.440
2pvlP55Casein kinase II subunit alpha2.7.11.10.440
2w6qOA5Biotin carboxylase6.3.4.140.440
2xvq9DSSerum albumin/0.440
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.440
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.440
3qlrNDPDihydrofolate reductase1.5.1.30.440
3ttjJBIMitogen-activated protein kinase 102.7.11.240.440
3w6hAZMCarbonic anhydrase 14.2.1.10.440
3zs7ATPPyridoxine/pyridoxal/pyridoxamine kinase/0.440
3zuyTCHTransporter/0.440
4a84DXCMajor pollen allergen Bet v 1-A/0.440
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.440
4awq592Heat shock protein HSP 90-alpha/0.440
4ejn0R4RAC-alpha serine/threonine-protein kinase2.7.11.10.440
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.440
4ewqMWLMitogen-activated protein kinase 14/0.440
4ho8THMGlucose-1-phosphate thymidylyltransferase/0.440
4lvg20ONicotinamide phosphoribosyltransferase2.4.2.120.440
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.440