sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3p9k | CIY | Caffeic acid O-methyltransferase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3p9k | CIY | Caffeic acid O-methyltransferase | / | 1.000 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.513 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.501 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.497 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.497 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.495 | |
| 1e7a | PFL | Serum albumin | / | 0.494 | |
| 4k5y | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.489 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.488 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.484 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.484 | |
| 1dfo | FFO | Serine hydroxymethyltransferase | 2.1.2.1 | 0.482 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.482 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.482 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.482 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.481 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.479 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.479 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 4isk | 1JY | Thymidylate synthase | / | 0.478 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.477 | |
| 3bzu | A21 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.477 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.477 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.476 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.476 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.474 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.474 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.473 | |
| 3i1y | 33N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.473 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.473 | |
| 1ep4 | S11 | Gag-Pol polyprotein | 2.7.7.49 | 0.472 | |
| 1xud | PB4 | Collagenase 3 | 3.4.24 | 0.472 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.472 | |
| 1egd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.471 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.471 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.470 | |
| 1ju6 | LYA | Thymidylate synthase | 2.1.1.45 | 0.470 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.470 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.470 | |
| 3t19 | 5MA | Gag-Pol polyprotein | 2.7.7.49 | 0.470 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.470 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.470 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.469 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.469 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.469 | |
| 3uwl | FOZ | Thymidylate synthase | / | 0.469 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.469 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.468 | |
| 2bra | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.468 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.468 | |
| 3hky | IX6 | Genome polyprotein | 2.7.7.48 | 0.468 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.467 | |
| 1wsv | THH | Aminomethyltransferase, mitochondrial | / | 0.467 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.467 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.467 | |
| 1juj | LYA | Thymidylate synthase | 2.1.1.45 | 0.466 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.466 | |
| 3e01 | PZ2 | Gag-Pol polyprotein | 2.7.7.49 | 0.466 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.466 | |
| 5dp2 | NAP | CurF | / | 0.466 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.465 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.465 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.465 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.464 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.464 | |
| 3stv | 3HO | Methylketone synthase I | / | 0.464 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.464 | |
| 1s36 | CEI | Obelin | / | 0.463 | |
| 3cox | FAD | Cholesterol oxidase | 1.1.3.6 | 0.463 | |
| 3dya | PZL | Gag-Pol polyprotein | 2.7.7.49 | 0.463 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.463 | |
| 3up0 | D7S | aceDAF-12 | / | 0.463 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.462 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.462 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.462 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.462 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.462 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.462 | |
| 4zvm | DM2 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.462 | |
| 2avi | BTN | Avidin | / | 0.461 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.461 | |
| 2igy | A2T | Plasmepsin 2 | / | 0.461 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.461 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 4z9g | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.461 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.461 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.460 | |
| 3dlg | GWE | Gag-Pol polyprotein | 2.7.7.49 | 0.460 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.460 | |
| 4hl1 | ZZ7 | Metallo-beta-lactamase type 2 | / | 0.460 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.460 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.459 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.459 | |
| 1suw | NAP | NAD kinase | / | 0.459 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.459 | |
| 2pmd | GNP | Translation initiation factor 2 subunit gamma | / | 0.459 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.459 | |
| 3rus | ADP | Chaperonin | / | 0.459 | |
| 3v76 | FDA | Uncharacterized protein | / | 0.459 | |
| 3w0t | HPU | Lactoylglutathione lyase | 4.4.1.5 | 0.459 | |
| 4a0s | CO8 | Octenoyl-CoA reductase/carboxylase | / | 0.459 | |
| 4cav | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.459 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.459 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.459 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.459 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.459 | |
| 1xur | PB5 | Collagenase 3 | 3.4.24 | 0.458 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.458 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.458 | |
| 3nax | MP7 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.458 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.458 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.458 | |
| 1mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.457 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.457 | |
| 2wd9 | IBP | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.457 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.457 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.457 | |
| 1lco | PPY | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.456 | |
| 1tys | DHF | Thymidylate synthase | / | 0.456 | |
| 2rc6 | NAP | Ferredoxin--NADP reductase | / | 0.456 | |
| 2z1q | FAD | Acyl-CoA dehydrogenase | / | 0.456 | |
| 3dok | GWJ | Pol protein | / | 0.456 | |
| 3vi7 | CBD | Hematopoietic prostaglandin D synthase | / | 0.456 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.456 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.456 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.456 | |
| 1zdw | FLV | Prenyltransferase | / | 0.455 | |
| 3bhl | THG | Thymidylate synthase | / | 0.455 | |
| 4i7f | NVE | Gag-Pol polyprotein | 2.7.7.49 | 0.455 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.454 | |
| 1efa | NPF | Lactose operon repressor | / | 0.454 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.454 | |
| 1w7k | ADP | Dihydrofolate synthase/folylpolyglutamate synthase | 6.3.2.12 | 0.454 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 2vf0 | F89 | Thymidylate synthase | / | 0.454 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.454 | |
| 3dol | GWI | Pol protein | / | 0.454 | |
| 3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.454 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.454 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.454 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.453 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.453 | |
| 1xuc | PB3 | Collagenase 3 | 3.4.24 | 0.453 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.453 | |
| 3pz3 | PZ3 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.453 | |
| 3t1a | 5MA | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.453 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.453 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.452 | |
| 2qta | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.452 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.452 | |
| 3dmj | GWE | Pol protein | / | 0.452 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.452 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.452 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.452 | |
| 4a6e | ASE | Acetylserotonin O-methyltransferase | 2.1.1.4 | 0.452 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.452 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.452 | |
| 4ydd | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.452 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.452 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.451 | |
| 1kqo | DND | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.451 | |
| 1zx1 | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.451 | |
| 2xgo | ZKD | Uncharacterized protein | / | 0.451 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.451 | |
| 3q0u | LL3 | HTH-type transcriptional regulator EthR | / | 0.451 | |
| 3sfi | 3SF | HTH-type transcriptional regulator EthR | / | 0.451 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.451 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.451 | |
| 4h4o | 506 | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.451 | |
| 4ug2 | NGI | Adenosine receptor A2a | / | 0.451 | |
| 1al7 | HST | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.450 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1lhv | NOG | Sex hormone-binding globulin | / | 0.450 | |
| 2dr3 | ADP | UPF0273 protein PH0284 | / | 0.450 | |
| 2ynh | EUR | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.450 | |
| 3oev | 3OE | Proteasome subunit beta type-5 | 3.4.25.1 | 0.450 | |
| 3oev | 3OE | Proteasome subunit beta type-6 | 3.4.25.1 | 0.450 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.450 | |
| 3sjz | GNP | Translation initiation factor 2 subunit gamma | / | 0.450 | |
| 3uic | 09T | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.450 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.450 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.449 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.449 | |
| 3thr | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.449 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.449 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.449 | |
| 5cp8 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 10mh | SAH | Modification methylase HhaI | 2.1.1.37 | 0.448 | |
| 1cc2 | FAD | Cholesterol oxidase | 1.1.3.6 | 0.448 | |
| 1dnp | MHF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.448 | |
| 2hnz | PC0 | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.448 | |
| 3ix8 | TX3 | Transcriptional activator protein LasR | / | 0.448 | |
| 3zc3 | NAP | Ferredoxin--NADP reductase | 1.18.1.2 | 0.448 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.448 | |
| 4rrf | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.448 | |
| 4xwr | FAD | Cholesterol oxidase | 1.1.3.6 | 0.448 | |
| 4z28 | BTN | Hoefavidin | / | 0.448 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.447 | |
| 1eqb | FFO | Serine hydroxymethyltransferase | 2.1.2.1 | 0.447 | |
| 1kyz | FER | Caffeic acid 3-O-methyltransferase | 2.1.1.68 | 0.447 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.447 | |
| 1tsd | F89 | Thymidylate synthase | / | 0.447 | |
| 2aaz | CB3 | Thymidylate synthase | 2.1.1.45 | 0.447 | |
| 2hu6 | 37A | Macrophage metalloelastase | 3.4.24.65 | 0.447 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.447 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.447 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.447 | |
| 4bfp | SWY | Tankyrase-2 | 2.4.2.30 | 0.447 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.447 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.447 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.447 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.447 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.446 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.446 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.446 | |
| 2pa7 | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.446 | |
| 3lal | KRV | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 3nf7 | CIW | Gag-Pol polyprotein | / | 0.446 | |
| 3ol5 | SAW | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3ruv | ANP | Chaperonin | / | 0.446 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4gev | CB3 | Thymidylate synthase | / | 0.446 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.446 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.446 | |
| 5emh | NAP | Iridoid synthase | 1.3.1.99 | 0.446 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.446 | |
| 1an5 | CB3 | Thymidylate synthase | / | 0.445 | |
| 1cbo | FAD | Cholesterol oxidase | 1.1.3.6 | 0.445 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.445 | |
| 1stp | BTN | Streptavidin | / | 0.445 | |
| 2vcg | S17 | Histone deacetylase-like amidohydrolase | 3.5.1 | 0.445 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.445 | |
| 4aos | FAD | Steroid monooxygenase | / | 0.445 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 4xrg | NAD | Homospermidine synthase | 2.5.1.44 | 0.445 | |
| 5a3c | NAD | SIR2 family protein | / | 0.445 | |
| 5ag5 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.444 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1ndy | FR3 | Adenosine deaminase | 3.5.4.4 | 0.444 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.444 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.444 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.444 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.444 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.444 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2zsc | BTN | Tamavidin2 | / | 0.444 | |
| 3b82 | NAD | Exotoxin A | 2.4.2.36 | 0.444 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.444 | |
| 3up3 | XCA | aceDAF-12 | / | 0.444 | |
| 4hdr | DMD | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | / | 0.444 | |
| 4hdr | DMD | ArsB | / | 0.444 | |
| 4myq | 19T | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.444 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.444 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.444 | |
| 5dq8 | FLF | Transcriptional enhancer factor TEF-4 | / | 0.444 | |
| 1d3g | BRE | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.443 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.443 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.443 | |
| 1syn | F89 | Thymidylate synthase | / | 0.443 | |
| 2hq9 | FAD | Mll6688 protein | / | 0.443 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 2uyw | BTN | Avd protein | / | 0.443 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.443 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.443 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.443 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 3nhk | VAP | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.443 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3o2x | 3O2 | Collagenase 3 | 3.4.24 | 0.443 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.443 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 4tzk | 641 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4u2s | FDA | Cholesterol oxidase | 1.1.3.6 | 0.443 | |
| 5cb5 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.443 | |
| 5d1b | TSN | Histone deacetylase 8 | 3.5.1.98 | 0.443 | |
| 5hsa | FAS | Alcohol oxidase 1 | 1.1.3.13 | 0.443 | |
| 1fwm | CB3 | Thymidylate synthase | / | 0.442 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.442 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.442 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.442 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2xvv | 9DN | Serum albumin | / | 0.442 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.442 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.442 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.442 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.442 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.442 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.442 | |
| 3s41 | S41 | Glucokinase | 2.7.1.2 | 0.442 | |
| 3tyv | HI3 | Genome polyprotein | 2.7.7.48 | 0.442 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4b4b | GJB | Glucose-1-phosphate thymidylyltransferase | / | 0.442 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.442 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.442 | |
| 1fcy | 564 | Retinoic acid receptor gamma | / | 0.441 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.441 | |
| 1nq2 | 4HY | Thyroid hormone receptor beta | / | 0.441 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.441 | |
| 1z0z | NAD | NAD kinase | / | 0.441 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.441 | |
| 2uxw | TH3 | Very long-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.9 | 0.441 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2woe | AR6 | ADP-ribosyl-[dinitrogen reductase] glycohydrolase | 3.2.2.24 | 0.441 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.441 | |
| 3aba | FLI | Cytochrome P450 | / | 0.441 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.441 | |
| 3uph | 0C1 | Genome polyprotein | 2.7.7.48 | 0.441 | |
| 4c3x | FAD | 3-ketosteroid dehydrogenase | / | 0.441 | |
| 4dsh | FDA | Uncharacterized protein | / | 0.441 | |
| 4hlf | 15Z | Tankyrase-2 | 2.4.2.30 | 0.441 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.441 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.441 | |
| 1pox | FAD | Pyruvate oxidase | 1.2.3.3 | 0.440 | |
| 1r2j | FAD | FkbI | / | 0.440 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.440 | |
| 2ofv | 242 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.440 | |
| 2ore | SAH | DNA adenine methylase | 2.1.1.72 | 0.440 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 3g1m | RF3 | HTH-type transcriptional regulator EthR | / | 0.440 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.440 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.440 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.440 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.440 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.440 | |
| 3x2f | NAI | Adenosylhomocysteinase | / | 0.440 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.440 | |
| 4n3r | 2GU | Tankyrase-1 | 2.4.2.30 | 0.440 | |
| 4xqc | NAD | Homospermidine synthase | 2.5.1.44 | 0.440 | |
| 5mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.440 |