sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3p17 | 99P | Prothrombin | 3.4.21.5 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 1.000 | |
| 3qto | 10P | Prothrombin | 3.4.21.5 | 0.863 | |
| 3qtv | 06P | Prothrombin | 3.4.21.5 | 0.810 | |
| 4bao | MVF | Prothrombin | 3.4.21.5 | 0.766 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.752 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.751 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.751 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.738 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.730 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.727 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.724 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.719 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.718 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.698 | |
| 2zfp | 19U | Prothrombin | 3.4.21.5 | 0.694 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.687 | |
| 3utu | 1TS | Prothrombin | 3.4.21.5 | 0.684 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.681 | |
| 2zgb | 21U | Prothrombin | 3.4.21.5 | 0.681 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.680 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.678 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.677 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.676 | |
| 4bah | MEL | Prothrombin | 3.4.21.5 | 0.675 | |
| 2zg0 | 50U | Prothrombin | 3.4.21.5 | 0.671 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.670 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.664 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.655 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.655 | |
| 1ypm | RA4 | Prothrombin | 3.4.21.5 | 0.653 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.652 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.650 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.648 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.644 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.642 | |
| 1k22 | MEL | Prothrombin | 3.4.21.5 | 0.641 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.641 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.640 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.634 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.631 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.626 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.626 | |
| 4bak | M67 | Prothrombin | 3.4.21.5 | 0.626 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.624 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.622 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.620 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.619 | |
| 3dux | 64U | Prothrombin | 3.4.21.5 | 0.619 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.607 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.605 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.605 | |
| 2zf0 | 51U | Prothrombin | 3.4.21.5 | 0.605 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.602 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.601 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.601 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.599 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.596 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.594 | |
| 4az2 | 9MU | Prothrombin | 3.4.21.5 | 0.593 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.589 | |
| 1vzq | SHY | Prothrombin | 3.4.21.5 | 0.589 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.587 | |
| 2bxt | C2D | Prothrombin | 3.4.21.5 | 0.587 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.586 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.586 | |
| 4baq | M4Z | Prothrombin | 3.4.21.5 | 0.586 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.585 | |
| 4ayy | 9MX | Prothrombin | 3.4.21.5 | 0.585 | |
| 4lxb | 7R9 | Prothrombin | 3.4.21.5 | 0.585 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.584 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.584 | |
| 7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.584 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.583 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.581 | |
| 4ban | M6S | Prothrombin | 3.4.21.5 | 0.580 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.579 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.576 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.575 | |
| 4e7r | 0NW | Prothrombin | 3.4.21.5 | 0.575 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.571 | |
| 1a4w | QWE | Prothrombin | 3.4.21.5 | 0.569 | |
| 2uuj | 896 | Prothrombin | 3.4.21.5 | 0.566 | |
| 1w7g | MIU | Prothrombin | 3.4.21.5 | 0.561 | |
| 1k21 | IGN | Prothrombin | 3.4.21.5 | 0.560 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.559 | |
| 2cf8 | ESH | Prothrombin | 3.4.21.5 | 0.559 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.558 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.555 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.555 | |
| 4hfp | 15U | Prothrombin | 3.4.21.5 | 0.548 | |
| 4rn6 | 15U | Prothrombin | 3.4.21.5 | 0.548 | |
| 3biv | 11U | Prothrombin | 3.4.21.5 | 0.545 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.544 | |
| 2gde | SN3 | Prothrombin | 3.4.21.5 | 0.543 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.542 | |
| 3qdz | PRO_ALA_PRO_ARG | Prothrombin | 3.4.21.5 | 0.538 | |
| 2cf9 | 348 | Prothrombin | 3.4.21.5 | 0.537 | |
| 1riw | OSC | Prothrombin | 3.4.21.5 | 0.536 | |
| 3dhk | 23U | Prothrombin | 3.4.21.5 | 0.536 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.533 | |
| 1ghv | 120 | Prothrombin | 3.4.21.5 | 0.527 | |
| 2ziq | 26U | Prothrombin | 3.4.21.5 | 0.526 | |
| 1c4v | IH2 | Prothrombin | 3.4.21.5 | 0.524 | |
| 1ny2 | ARG_PRO_PRO_GLY | Prothrombin | 3.4.21.5 | 0.524 | |
| 1mu8 | CDB | Prothrombin | 3.4.21.5 | 0.510 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.509 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.501 | |
| 1o0d | 163 | Prothrombin | 3.4.21.5 | 0.496 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.494 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.491 | |
| 3egk | M18 | Prothrombin | 3.4.21.5 | 0.489 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.486 | |
| 4ayv | 9MQ | Prothrombin | 3.4.21.5 | 0.485 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.484 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.482 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.481 | |
| 4loy | 6XS | Prothrombin | 3.4.21.5 | 0.480 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.479 | |
| 1c7o | PPG | Hemolysin | / | 0.477 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.476 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.474 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.473 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.473 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.471 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.470 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.469 | |
| 3f68 | 91U | Prothrombin | 3.4.21.5 | 0.469 | |
| 3lkh | LT6 | Genome polyprotein | 2.7.7.48 | 0.469 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.468 | |
| 3eku | CY9 | Actin-5C | / | 0.468 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.468 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.468 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.466 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.466 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.465 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.465 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.465 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.465 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.465 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.465 | |
| 1ja0 | FAD | NADPH--cytochrome P450 reductase | / | 0.464 | |
| 1knr | FAD | L-aspartate oxidase | 1.4.3.16 | 0.464 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.464 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.464 | |
| 4eu8 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.464 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.464 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.463 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.462 | |
| 1fml | RTL | Retinol dehydratase | / | 0.461 | |
| 1ta2 | 176 | Prothrombin | 3.4.21.5 | 0.461 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.461 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 1uvs | I11 | Prothrombin | 3.4.21.5 | 0.460 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 1c1u | BAI | Prothrombin | 3.4.21.5 | 0.459 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.459 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.459 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.459 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.459 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.459 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.458 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.458 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.458 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.458 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.457 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.457 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.457 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.457 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.456 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.456 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.456 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.456 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.456 | |
| 4b0c | C9H | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase | 4.2.1.59 | 0.456 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.456 | |
| 1ppj | ANY | Cytochrome b | / | 0.455 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.455 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.455 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.455 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.455 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 4e2b | FMN | Dehydrogenase | / | 0.455 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.455 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.454 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.454 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.453 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.453 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.453 | |
| 3wtk | TH4 | Acetylcholine-binding protein | / | 0.453 | |
| 4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.453 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.453 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.452 | |
| 2b8l | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.452 | |
| 2ej2 | PPE | Branched-chain amino acid aminotransferase (IlvE) | / | 0.452 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.452 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.452 | |
| 4kwc | SAH | Methyltransferase domain family | / | 0.452 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.451 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.451 | |
| 3vg1 | 0GT | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.450 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.450 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.450 | |
| 4pzr | COA | Histone acetyltransferase p300 | / | 0.450 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.450 | |
| 1r2j | FAD | FkbI | / | 0.449 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.449 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.449 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.449 | |
| 3qbh | QBH | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.449 | |
| 1u1i | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.448 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.448 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.448 | |
| 4frj | DWB | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.447 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.447 | |
| 1pfy | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.446 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.446 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 1zp3 | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.446 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.446 | |
| 3c15 | FOK | Adenylate cyclase type 2 | / | 0.446 | |
| 3c15 | FOK | Adenylate cyclase type 5 | / | 0.446 | |
| 3ean | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.446 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.446 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.446 | |
| 3qvi | K95 | HAP protein | / | 0.446 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.446 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.446 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2hld | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.445 | |
| 2hld | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.445 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.445 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.445 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.445 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.445 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.445 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.445 | |
| 3kpb | SAM | Uncharacterized protein MJ0100 | / | 0.445 | |
| 3rq6 | APR | ADP-dependent (S)-NAD(P)H-hydrate dehydratase | / | 0.445 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.445 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.444 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.444 | |
| 1w4x | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.444 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.444 | |
| 2bbw | GP5 | Adenylate kinase 4, mitochondrial | / | 0.444 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.444 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.444 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
| 3v2u | ATP | Protein GAL3 | / | 0.444 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.444 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.443 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.443 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.443 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.443 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.443 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.443 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.443 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.443 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.442 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.442 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.442 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.442 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.442 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.442 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.442 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.442 | |
| 4k8s | 1QT | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4prx | ADP | DNA gyrase subunit B | / | 0.442 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.442 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.442 | |
| 1gvh | FAD | Flavohemoprotein | / | 0.441 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.441 | |
| 2q15 | 3MR | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.441 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.441 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 5doz | NDP | JamJ | / | 0.441 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.440 | |
| 1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.440 | |
| 2wf3 | ZY3 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.440 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.440 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4btt | VYR | Coagulation factor X | 3.4.21.6 | 0.440 | |
| 4dpi | 0N1 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.440 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.440 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.440 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.440 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.440 |