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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3ozsOZSCatechol O-methyltransferase2.1.1.6

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3ozsOZSCatechol O-methyltransferase2.1.1.61.000
3oztOZZCatechol O-methyltransferase2.1.1.60.616
3r6tLU1Catechol O-methyltransferase2.1.1.60.571
3nwe662Catechol O-methyltransferase2.1.1.60.548
3a7dFBNCatechol O-methyltransferase2.1.1.60.534
1jr4CL4Catechol O-methyltransferase2.1.1.60.531
3nw9637Catechol O-methyltransferase2.1.1.60.515
3oe4610Catechol O-methyltransferase2.1.1.60.514
3nwb659Catechol O-methyltransferase2.1.1.60.499
3hvk719Catechol O-methyltransferase2.1.1.60.486
3oe5611Catechol O-methyltransferase2.1.1.60.469
3ozrOZRCatechol O-methyltransferase2.1.1.60.449
3a25SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase/0.446