sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3okx | SAM | S-adenosyl-L-methionine-binding protein RPA0152 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3okx | SAM | S-adenosyl-L-methionine-binding protein RPA0152 | / | 1.000 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.475 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.474 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.471 | |
| 1c6y | MK1 | Protease | / | 0.468 | |
| 3zc3 | NAP | Ferredoxin--NADP reductase | 1.18.1.2 | 0.461 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 4l3j | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.454 | |
| 1hsg | MK1 | Gag-Pol polyprotein | / | 0.453 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 3el9 | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 3nwq | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 2avv | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 2bqv | A1A | Protease | / | 0.451 | |
| 3wec | AUI | Cytochrome P450 | / | 0.451 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1hii | C20 | Gag-Pol polyprotein | / | 0.450 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.450 | |
| 2y8l | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.450 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.447 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.447 | |
| 2bb9 | AKC | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.447 | |
| 3ics | COA | Coenzyme A disulfide reductase | / | 0.447 | |
| 3nxe | 2NC | Protease | / | 0.447 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.446 | |
| 4bbe | 3O4 | Tyrosine-protein kinase JAK2 | / | 0.446 | |
| 2ya3 | J7V | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.445 | |
| 1sdu | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2p4y | C03 | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2q63 | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1vp6 | CMP | Cyclic nucleotide-gated potassium channel mll3241 | / | 0.443 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.443 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 1eby | BEB | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.442 | |
| 2q64 | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.442 | |
| 4a4w | YFB | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1sdv | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.441 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.440 |