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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3oijSAHRibosomal RNA small subunit methyltransferase NEP1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3oijSAHRibosomal RNA small subunit methyltransferase NEP1/1.000
3oiiSAHRibosomal RNA small subunit methyltransferase NEP1/0.635
4jwfSAHtRNA (guanine(9)-N1)-methyltransferase/0.535
3nk7SAM23S rRNA (adenosine(1067)-2'-O)-methyltransferase/0.517
3bbhSFGRibosomal RNA small subunit methyltransferase Nep12.1.10.515
4xczFONQdtf/0.509
2el0SAHDiphthine synthase/0.503
3bbdSAHRibosomal RNA small subunit methyltransferase Nep12.1.10.503
4pzkSAHPutative tRNA (cytidine(34)-2'-O)-methyltransferase/0.503
1lf2R37Plasmepsin-23.4.23.390.502
4bkqNAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.501
1n2hPAJPantothenate synthetase6.3.2.10.500
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.499
4yqfGDPSeptin-9/0.498
1t7kBH0Gag-Pol polyprotein3.4.23.160.497
3zhyFM61-deoxy-D-xylulose 5-phosphate reductoisomerase/0.497
4a0rDTBBifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial6.3.3.30.497
4kgnSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.497
4djhJDCKappa-type opioid receptor/0.497
3qpjN4IGag-Pol polyprotein3.4.23.160.496
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.495
3kdb006Gag-Pol polyprotein3.4.23.160.493
1zrzBI1Protein kinase C iota type2.7.11.130.491
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.491
2wsbNADGalactitol dehydrogenase/0.491
4hdpG52Gag-Pol polyprotein3.4.23.160.491
2cv2GSUGlutamate--tRNA ligase6.1.1.170.489
2fde385Gag-Pol polyprotein3.4.23.160.489
2qnqQN3Gag-Pol polyprotein3.4.23.160.489
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.489
3dk1G05Gag-Pol polyprotein3.4.23.160.489
2pncCLUPrimary amine oxidase, liver isozyme/0.488
3st5G89Gag-Pol polyprotein3.4.23.160.488
2ou5FMNPyridoxamine 5'-phosphate oxidase-related FMN-binding protein/0.486
3uylTYDProbable NDP-rhamnosyltransferase/0.486
3vfb031Gag-Pol polyprotein3.4.23.160.486
4a4qUX9Pol protein/0.486
1kp3ATPArgininosuccinate synthase6.3.4.50.485
1xe65FPPlasmepsin-23.4.23.390.485
2e8qSAHDiphthine synthase/0.485
2qd7065Gag-Pol polyprotein3.4.23.160.485
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.485
1xe55FEPlasmepsin-23.4.23.390.484
2dv3SAHDiphthine synthase/0.484
2qi4MZ6Gag-Pol polyprotein/0.484
3bgbLJGGag-Pol polyprotein3.4.23.160.484
3o9gF53Gag-Pol polyprotein/0.484
4q1x017Gag-Pol polyprotein3.4.23.160.483
4yaoFMNNADPH--cytochrome P450 reductase/0.483
1yqdNAPSinapyl alcohol dehydrogenase/0.482
2ha8SAHProbable methyltransferase TARBP1/0.482
3o9aK14Pol polyprotein/0.482
1wngSAHDiphthine synthase/0.481
3o9cK20Pol polyprotein/0.481
4ihl1F514-3-3 protein zeta/delta/0.481
2eglSAHDiphthine synthase/0.480
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.480
2z54AB1Gag-Pol polyprotein3.4.23.160.480
3udq09EBeta-secretase 13.4.23.460.480
4ef8FMNDihydroorotate dehydrogenase (fumarate)/0.480
2a4fAAUV-1 protease/0.479
2pwcG3GGag-Pol polyprotein3.4.23.160.479
3fr5I4AFatty acid-binding protein, adipocyte/0.479
3i60E86Mitogen-activated protein kinase 12.7.11.240.479
4opiFDAConserved Archaeal protein/0.479
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.478
2f2uM77Rho-associated protein kinase 22.7.11.10.478
2huqSAHDiphthine synthase/0.478
2ien017Gag-Pol polyprotein3.4.23.160.478
3a2oKNJGag-Pol polyprotein3.4.23.160.478
3omuIBDHeat shock protein 83/0.478
3qbfJHGGag-Pol polyprotein3.4.23.160.478
3rk1ATPN-type ATP pyrophosphatase superfamily/0.478
3s7dLEU_SER_LYS_LYS_MLZN-lysine methyltransferase SMYD2/0.478
4cqlNADEstradiol 17-beta-dehydrogenase 81.1.1.620.478
4i8zG08Gag-Pol polyprotein3.4.23.160.478
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.478
1bdlIM1Gag-Pol polyprotein3.4.23.160.477
1bdrIM1Gag-Pol polyprotein3.4.23.160.477
1ec3MS3Gag-Pol polyprotein3.4.23.160.477
1t2cNAIL-lactate dehydrogenase1.1.1.270.477
1t85CAMCamphor 5-monooxygenase1.14.15.10.477
2a94AP0L-lactate dehydrogenase1.1.1.270.477
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
2e07SAHDiphthine synthase/0.477
2ed5SAHDiphthine synthase/0.477
2ek7SAHDiphthine synthase/0.477
2g1r3IGRenin3.4.23.150.477
2vwqNAPGlucose 1-dehydrogenase/0.477
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.477
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.477
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.477
4xboSAHtRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ2.1.1.2000.477
1hiv1ZKGag-Pol polyprotein/0.476
1npvL27Gag-Pol polyprotein3.4.23.160.476
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
2ylzFADPhenylacetone monooxygenase1.14.13.920.476
3em4DR7Gag-Pol polyprotein3.4.23.160.476
3o7bSAHRibosomal RNA small subunit methyltransferase Nep1/0.476
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
1fej2NCGag-Pol polyprotein3.4.23.160.475
1qrpHH0Pepsin A-43.4.23.10.475
1t7i017Gag-Pol polyprotein3.4.23.160.475
2i0aMUIProtease/0.475
2il2LIXRenin3.4.23.150.475
3il1B5DGlutamate receptor 2/0.475
3sa8K83Protease/0.475
2bpz3INGag-Pol polyprotein3.4.23.160.474
3ai2NDPNADPH-sorbose reductase/0.474
3bgcLJHGag-Pol polyprotein3.4.23.160.474
3kf03TLGag-Pol polyprotein/0.474
3nu9478Gag-Pol polyprotein3.4.23.160.474
4loqSB4Mitogen-activated protein kinase 14/0.474
4rvj478Protease/0.474
4yj2GTPTubulin alpha-1B chain/0.474
1hvsA77Gag-Pol polyprotein/0.473
1psa0ZLPepsin A3.4.23.10.473
1vijBAYGag-Pol polyprotein/0.473
2g247IGRenin3.4.23.150.473
2i7pACOPantothenate kinase 32.7.1.330.473
2q3kMUWGag-Pol polyprotein/0.473
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
2zbaZBATrichothecene 3-O-acetyltransferase/0.473
3f8pNADNADH oxidase/thioredoxin reductase/0.473
3pwm017Gag-Pol polyprotein3.4.23.160.473
3qaaG04Gag-Pol polyprotein3.4.23.160.473
4dbzNDPPutative ketoacyl reductase1.3.10.473
4eueNAITrans-2-enoyl-CoA reductase [NADH]/0.473
1ffi2NCGag-Pol polyprotein3.4.23.160.472
1gthFADDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.472
1o76CAMCamphor 5-monooxygenase1.14.15.10.472
1z1rHBHGag-Pol polyprotein3.4.23.160.472
2ejjSAHDiphthine synthase/0.472
2eleSAHDiphthine synthase/0.472
2jlcTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.472
2qnnQN1Gag-Pol polyprotein3.4.23.160.472
3c35KAIGlutamate receptor ionotropic, kainate 1/0.472
3el01UNGag-Pol polyprotein3.4.23.160.472
3lqfNADGalactitol dehydrogenase/0.472
3qrsNK8Gag-Pol polyprotein3.4.23.160.472
4ke11R6Beta-secretase 13.4.23.460.472
1p0fNAPNADP-dependent alcohol dehydrogenase1.1.1.20.471
2egbSAHDiphthine synthase/0.471
2iyfERYOleandomycin glycosyltransferase2.4.10.471
2p3b3TLV-1 PROTEASE protein/0.471
2p3b3TLV-1 protease/0.471
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.471
2zz0FADThioredoxin reductase 1, cytoplasmic1.8.1.90.471
3lb8FADPutidaredoxin reductase1.18.1.50.471
3okxSAMS-adenosyl-L-methionine-binding protein RPA0152/0.471
3s1dZIRCytokinin dehydrogenase 11.5.99.120.471
3tjzGNPADP-ribosylation factor 1/0.471
3tog079Gag-Pol polyprotein2.7.7.490.471
4bmoFMNProtein NrdI/0.471
4qxr1YEStimulator of interferon genes protein/0.471
1kfbIGPTryptophan synthase alpha chain/0.470
1lbcCYZGlutamate receptor 2/0.470
1msmJE2Gag-Pol polyprotein3.4.23.160.470
1vhzAPRADP compounds hydrolase NudE3.6.10.470
2a7r5GPGMP reductase 2/0.470
2gd6ACOProbable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.470
2xhd7T9Glutamate receptor 2/0.470
3a3gDLZLumazine protein/0.470
4dqb017Gag-Pol polyprotein/0.470
4kb9G79Protease/0.470
1proA88Gag-Pol polyprotein/0.469
1w4xFADPhenylacetone monooxygenase1.14.13.920.469
2bgiFADNADPH:ferredoxin reductase/0.469
2c6tDT5Cyclin-dependent kinase 22.7.11.220.469
2dxvSAHDiphthine synthase/0.469
2wdzNADGalactitol dehydrogenase/0.469
3i7eDJRGag-Pol polyprotein/0.469
3kdcJZPGag-Pol polyprotein3.4.23.160.469
3sm2478Putative gag-pro-pol polyprotein/0.469
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.469
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.469
5ejaTD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.469
1tv8SAMGTP 3',8-cyclase4.1.99.180.468
2aoe0Q4Gag-Pol polyprotein3.4.23.160.468
2owfSAHDiphthine synthase/0.468
3fwiCAMCamphor 5-monooxygenase1.14.15.10.468
3mt817TGlycogen phosphorylase, muscle form2.4.1.10.468
3wbbNAPMeso-diaminopimelate D-dehydrogenase/0.468
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.468
4jalSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.468
5ej6TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.468
1ec1BEEGag-Pol polyprotein3.4.23.160.467
1ee9NADMethylenetetrahydrofolate dehydrogenase [NAD(+)]1.5.1.150.467
1mxiSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.467
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.467
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
2pwrG4GGag-Pol polyprotein3.4.23.160.467
2q5kAB1Protease/0.467
2r3tG4GGag-Pol polyprotein3.4.23.160.467
3d1yROCGag-Pol polyprotein3.4.23.160.467
3r4b74TGag-Pol polyprotein/0.467
3vf5031Gag-Pol polyprotein3.4.23.160.467
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
4bqjXKLHeat shock protein HSP 90-alpha/0.467
4djoMK5Pol polyprotein/0.467
4ic7ANPMitogen-activated protein kinase 72.7.11.240.467
4j54G52Gag-Pol polyprotein3.4.23.160.467
1kfcIPLTryptophan synthase alpha chain/0.466
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.466
1t7j478Gag-Pol polyprotein3.4.23.160.466
1wc4APCAdenylate cyclase/0.466
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
2dftADPShikimate kinase2.7.1.710.466
2e8sSAHDiphthine synthase/0.466
2rh9IGPTryptophan synthase alpha chain/0.466
3ioeA7DPantothenate synthetase6.3.2.10.466
3kb1ADPIron-sulfur cluster carrier protein/0.466
3o9iA61Gag-Pol polyprotein/0.466
3qe2FMNNADPH--cytochrome P450 reductase/0.466
3toxNAPPutative oxidoreductase/0.466
4dqc017Gag-Pol polyprotein/0.466
4mk029XBeta-adrenergic receptor kinase 12.7.11.150.466
1bv9XV6Gag-Pol polyprotein3.4.23.160.465
1c3eNHRPhosphoribosylglycinamide formyltransferase/0.465
1ja0FMNNADPH--cytochrome P450 reductase/0.465
1pjcNADAlanine dehydrogenase/0.465
1w6hTITPlasmepsin-23.4.23.390.465
2eh4SAHDiphthine synthase/0.465
2qd8065Gag-Pol polyprotein3.4.23.160.465
3cgeFADCoenzyme A disulfide reductase/0.465
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.465
3vyeVYERenin3.4.23.150.465
4dfg0JVGag-Pol polyprotein3.4.23.160.465
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.465
1owpFADDeoxyribodipyrimidine photo-lyase4.1.99.30.464
1p4aPCPPur operon repressor/0.464
2bn4FMNNADPH--cytochrome P450 reductase/0.464
2dxwSAHDiphthine synthase/0.464
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
2hb3GRLProtease/0.464
2hs2017Protease/0.464
2r3wG3GGag-Pol polyprotein3.4.23.160.464
2vw5BC6ATP-dependent molecular chaperone HSP82/0.464
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.464
3ekt017Gag-Pol polyprotein3.4.23.160.464
3gi6D78Gag-Pol polyprotein/0.464
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.464
3o99K13Pol polyprotein/0.464
3qp0NI8Gag-Pol polyprotein3.4.23.160.464
4djqM86Pol polyprotein/0.464
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.464
4k6fNAPPutative Acetoacetyl-CoA reductase/0.464
4la1FADThioredoxin glutathione reductase/0.464
4njvRITProtease/0.464
4ye3G04Gag-Pol polyprotein3.4.23.160.464
1n2jPAFPantothenate synthetase6.3.2.10.463
1nooCAHCamphor 5-monooxygenase1.14.15.10.463
1rf7DHFDihydrofolate reductase1.5.1.30.463
1sduMK1Gag-Pol polyprotein3.4.23.160.463
1zsr0ZTGag-Pol polyprotein3.4.23.160.463
2rcyNAPPyrroline-5-carboxylate reductase/0.463
2z6rSAHDiphthine synthase/0.463
3fwgCAMCamphor 5-monooxygenase1.14.15.10.463
3lzs017Gag-Pol polyprotein3.4.23.160.463
3psyRB9Endothiapepsin3.4.23.220.463
3sa4F72Protease/0.463
3t3c017Gag-Pol polyprotein3.4.23.160.463
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.463
4g3rCAMCamphor 5-monooxygenase1.14.15.10.463
4jwhSAHtRNA (guanine(9)-N1)-methyltransferase/0.463
4mcc21XtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.463
4q1y017Gag-Pol polyprotein3.4.23.160.463
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.462
2dekSAHDiphthine synthase/0.462
2ejkSAHDiphthine synthase/0.462
2hc0AB2Protease/0.462
2i4wKGQProtease/0.462
2nnkROCProtease/0.462
3d2pCOAAmino-acid acetyltransferase/0.462
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.462
3oy4017Gag-Pol polyprotein3.4.23.160.462
4bfwZVWPantothenate kinase2.7.1.330.462
4dqf017Gag-Pol polyprotein/0.462
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.462
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.462
4imoPWZProstaglandin-H2 D-isomerase5.3.99.20.462
4l4eCAMCamphor 5-monooxygenase1.14.15.10.462
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.462
1pg3PRXAcetyl-coenzyme A synthetase/0.461
2c29NAPDihydroflavonol 4-reductase/0.461
2cx8SAHRibosomal RNA small subunit methyltransferase E/0.461
2dsgSAHDiphthine synthase/0.461
2e8rSAHDiphthine synthase/0.461
2huxSAHDiphthine synthase/0.461
2i4xKGQProtease/0.461
2qi6MZ8Gag-Pol polyprotein/0.461
2r38G4GGag-Pol polyprotein3.4.23.160.461
3fg2FADPutative rubredoxin reductase/0.461
3ocpCMPcGMP-dependent protein kinase 12.7.11.120.461
3ojxFMNNADPH--cytochrome P450 reductase/0.461
3qvrFADGlucose oxidase1.1.3.40.461
3sabF78Protease/0.461
4hdfG52Gag-Pol polyprotein3.4.23.160.461
4kioG5KTyrosine-protein kinase ITK/TSK2.7.10.20.461
5c41ACPRibokinase/0.461
1d7aAIRN5-carboxyaminoimidazole ribonucleotide mutase/0.460
1h73ANPHomoserine kinase2.7.1.390.460
1hvjA78Gag-Pol polyprotein/0.460
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
1vceSAHDiphthine synthase/0.460
1x1bSAHC-20 methyltransferase/0.460
2e4nSAHDiphthine synthase/0.460
2ehlSAHDiphthine synthase/0.460
2f81017Gag-Pol polyprotein3.4.23.160.460
2hrbNAPCarbonyl reductase [NADPH] 31.1.1.1840.460
2hutSAHDiphthine synthase/0.460
2oapANPType II secretion system protein (GspE-2)/0.460
2psuMUUProtease/0.460
2qhyMZ1Gag-Pol polyprotein/0.460
2qnpQN2Gag-Pol polyprotein3.4.23.160.460
2r43G3GGag-Pol polyprotein3.4.23.160.460
2wkz5AHGag-Pol polyprotein/0.460
3bc3OPTCathepsin L13.4.22.150.460
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.460
3mxdK53Gag-Pol polyprotein3.4.23.160.460
3n4kSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.460
3qvsNADMyo-inositol-1-phosphate synthase (Ino1)/0.460
3sufSUEPolyprotein/0.460
3ucb017Gag-Pol polyprotein/0.460
4dptAGSMevalonate diphosphate decarboxylase/0.460
4i0j842Beta-secretase 13.4.23.460.460
4qgiROCGag-Pol polyprotein3.4.23.160.460
4xguADPPutative pachytene checkpoint protein 2/0.460
1m9k7NINitric oxide synthase, endothelial1.14.13.390.459
1t3r017Gag-Pol polyprotein3.4.23.160.459
2a1oCAMCamphor 5-monooxygenase1.14.15.10.459
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
2qd6065Gag-Pol polyprotein3.4.23.160.459
2qhzMZ2Gag-Pol polyprotein/0.459
2qs1UB1Glutamate receptor ionotropic, kainate 1/0.459
3em3478Gag-Pol polyprotein3.4.23.160.459
3i2l2NCProtease/0.459
3lpkZ76Beta-secretase 13.4.23.460.459
4fkr45KCyclin-dependent kinase 22.7.11.220.459
4j4nD44Peptidylprolyl isomerase/0.459
4m9aFDAAcyl-CoA dehydrogenase/0.459
4nwzFADFAD-dependent pyridine nucleotide-disulfide oxidoreductase/0.459
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.459
1e3eNAIAlcohol dehydrogenase 41.1.1.10.458
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.458
1m9m6NINitric oxide synthase, endothelial1.14.13.390.458
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.458
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
2bpw1INGag-Pol polyprotein3.4.23.160.458
2dvlFADAcyl-CoA dehydrogenase/0.458
2e16SAHDiphthine synthase/0.458
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
2g1o2IGRenin3.4.23.150.458
2hk9NAPShikimate dehydrogenase (NADP(+))/0.458
2p6iSAHDiphthine synthase/0.458
2pk6O33V-1 protease/0.458
2vcj2EQHeat shock protein HSP 90-alpha/0.458
3ai3NDPNADPH-sorbose reductase/0.458
3ndxRITGag-Pol polyprotein3.4.23.160.458
3s54017Protease/0.458
3vyfVYFRenin3.4.23.150.458
3wqmB29Diterpene synthase3.1.7.80.458
4l4fCAMCamphor 5-monooxygenase1.14.15.10.458
4oplFDAConserved Archaeal protein/0.458
4pvdNDPNADPH-dependent methylglyoxal reductase GRE2/0.458
1hbvGANGag-Pol polyprotein/0.457
1hvkA79Gag-Pol polyprotein/0.457
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
2owuSAHDiphthine synthase/0.457
2p6dSAHDiphthine synthase/0.457
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.457
3cyxROCGag-Pol polyprotein3.4.23.160.457
3e8nVRADual specificity mitogen-activated protein kinase kinase 12.7.12.20.457
3jvy017Gag-Pol polyprotein3.4.23.160.457
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.457
3mx5UTPNucleoprotein/0.457
3oxw017Gag-Pol polyprotein3.4.23.160.457
4bupSAMHistone-lysine N-methyltransferase KMT5B2.1.1.430.457
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
4hvg19QTyrosine-protein kinase JAK32.7.10.20.457
4nbwNADShort-chain dehydrogenase/reductase SDR/0.457
4ogkTHMUridine phosphorylase2.4.2.30.457
5cyoGDPSeptin-9/0.457
1a9mU0EGag-Pol polyprotein/0.456
1b6kPI5Gag-Pol polyprotein3.4.23.160.456
1bdbNADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase/0.456
1f8wFADNADH peroxidase1.11.1.10.456
1k7fIAVTryptophan synthase alpha chain/0.456
1muiAB1Protease/0.456
1qaqSFGrRNA adenine N-6-methyltransferase2.1.1.1840.456
1w5yBE6Gag-Pol polyprotein3.4.23.160.456
1y56ATPUncharacterized protein/0.456
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
2cjfRP43-dehydroquinate dehydratase4.2.1.100.456
2cmoM1LGlutamate receptor 2/0.456
2f80017Gag-Pol polyprotein3.4.23.160.456
2g1s4IGRenin3.4.23.150.456
2g20L1ARenin3.4.23.150.456
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.456
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.456
2idw017Protease/0.456
2pchSAHDiphthine synthase/0.456
2pqzG0GGag-Pol polyprotein3.4.23.160.456
2q54MU1Protease/0.456
2q631UNGag-Pol polyprotein3.4.23.160.456
3ekwDR7Gag-Pol polyprotein3.4.23.160.456
3fwrADPTranscriptional repressor CcpN/0.456
3ijrNADOxidoreductase, short chain dehydrogenase/reductase family/0.456
3kxw1ZZSaframycin Mx1 synthetase B/0.456
3linE13Protease/0.456
3oqfS51Renin3.4.23.150.456
3uhl2NCGag-Pol polyprotein3.4.23.160.456
3ut5LOCTubulin beta chain/0.456
3x2eNAIAdenosylhomocysteinase/0.456
4aqc88ATyrosine-protein kinase JAK2/0.456
4b722FBBeta-secretase 13.4.23.460.456
4blsAPCNTPase P4/0.456
4djr0KJPol polyprotein/0.456
4djy0KRBeta-secretase 13.4.23.460.456
4dqh017Gag-Pol polyprotein/0.456
4fj0NAP17beta-hydroxysteroid dehydrogenase/0.456
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.456
4is3NAD3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 21.17.98.10.456
4kgkGTPUncharacterized protein/0.456
4m6jNDPDihydrofolate reductase1.5.1.30.456
4ww0ADPATP-dependent zinc metalloprotease FtsH/0.456
4y93746Tyrosine-protein kinase/0.456
1ajxAH1Gag-Pol polyprotein3.4.23.160.455
1d4jMSCGag-Pol polyprotein3.4.23.160.455
1hiiC20Gag-Pol polyprotein/0.455
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.455
1me6IVSPlasmepsin-23.4.23.390.455
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.455
1xh9R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
2bpy3INGag-Pol polyprotein3.4.23.160.455
2cv1ATPGlutamate--tRNA ligase6.1.1.170.455
2dv7SAHDiphthine synthase/0.455
2g1y5IGRenin3.4.23.150.455
2iqgF2IBeta-secretase 13.4.23.460.455
2pb5SAHDiphthine synthase/0.455
2qbuSAHPrecorrin-2 methyltransferase/0.455
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
2xfyACXBeta-amylase3.2.1.20.455
2z3nPHE_ARG_TYR_LEU_GLYLeucyl/phenylalanyl-tRNA--protein transferase2.3.2.60.455
3clsFADElectron transfer flavoprotein subunit alpha/0.455
3ft5MO8Heat shock protein HSP 90-alpha/0.455
3gi5K62Gag-Pol polyprotein/0.455
3qfrFMNNADPH--cytochrome P450 reductase/0.455
3s8pSAMHistone-lysine N-methyltransferase KMT5B2.1.1.430.455
3ttp017Gag-Pol polyprotein3.4.23.160.455
3vf7031Gag-Pol polyprotein3.4.23.160.455
3vfa031Gag-Pol polyprotein3.4.23.160.455
4dx9SER_ALA_VAL_THRIntegrin beta-1/0.455
4dx9SER_ALA_VAL_THRIntegrin beta-1-binding protein 1/0.455
4f32N323-oxoacyl-[acyl-carrier-protein] synthase 2/0.455
4nm9FADBifunctional protein PutA/0.455
4qxq1YEStimulator of interferon genes protein/0.455
1gcoNADGlucose 1-dehydrogenase1.1.1.470.454
1hsgMK1Gag-Pol polyprotein/0.454
1iiq0ZRGag-Pol polyprotein3.4.23.160.454
1k6pXN3Gag-Pol polyprotein3.4.23.160.454
1obbNADAlpha-glucosidase3.2.1.200.454
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
1xddAAYIntegrin alpha-L/0.454
2a1y5GPGMP reductase/0.454
2b53D23Cyclin-dependent kinase 22.7.11.220.454
2e08SAHDiphthine synthase/0.454
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.454
2he5NDPAldo-keto reductase family 1 member C211.1.10.454
2i4vDJRV-1 protease/0.454
2i51FMNPyridoxamine 5'-phosphate oxidase-related, FMN-binding/0.454
2j9mPY8Cyclin-dependent kinase 22.7.11.220.454
2ojj82AMitogen-activated protein kinase 12.7.11.240.454
2qi3MZ5Gag-Pol polyprotein/0.454
3ec0GRLGag-Pol polyprotein3.4.23.470.454
3ekv478Gag-Pol polyprotein3.4.23.160.454
3ggaGGWGag-Pol polyprotein/0.454
3h8bNSYCathepsin L13.4.22.150.454
3rupADPBiotin carboxylase6.3.4.140.454
3s87ADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.454
3zewSTUEphrin type-B receptor 42.7.10.10.454
4bquCLRJapanin/0.454
4ek1CAMCamphor 5-monooxygenase1.14.15.10.454
4eudCOASuccinyl-CoA:acetate CoA-transferase/0.454
4g74FADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.454
4n6hEJ4Delta-type opioid receptor/0.454
4wzhFMNDihydroorotate dehydrogenase (fumarate)/0.454
5kwvANPPantothenate synthetase/0.454
1ivp1ZKGag-Pol polyprotein/0.453
1jik545Tyrosine--tRNA ligase/0.453
1ky4NADAdenosylhomocysteinase3.3.1.10.453
1o9bNAIQuinate/shikimate dehydrogenase/0.453
1rneC60Renin3.4.23.150.453
1tytFADTrypanothione reductase1.8.1.120.453
1w2xRCPAcetyl-CoA carboxylase/0.453
1zrqFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.453
2dv4SAHDiphthine synthase/0.453
2ed3SAHDiphthine synthase/0.453
2eufLQQCyclin-dependent kinase 62.7.11.220.453
2f3kRO1Protease/0.453
2fy4COACholine O-acetyltransferase2.3.1.60.453
2g226IGRenin3.4.23.150.453
2i4qUA4Renin3.4.23.150.453
2p5uNADUDP-glucose 4-epimerase/0.453
2pciSAHDiphthine synthase/0.453
2qbmCAMCamphor 5-monooxygenase1.14.15.10.453
2qci065Gag-Pol polyprotein3.4.23.160.453
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
2uwd2GGHeat shock protein HSP 90-alpha/0.453
2uzlC94Cyclin-dependent kinase 22.7.11.220.453
2xyrSFGReplicase polyprotein 1ab2.1.10.453
3cyw017Gag-Pol polyprotein3.4.23.160.453
3dogNNNCyclin-dependent kinase 22.7.11.220.453
3ekp478Gag-Pol polyprotein3.4.23.160.453
3lzu017Gag-Pol polyprotein3.4.23.160.453
3o9dK19Pol polyprotein/0.453
3qn8NI7Gag-Pol polyprotein3.4.23.160.453
3s43478Protease/0.453
4h2dFMNNADPH-dependent diflavin oxidoreductase 1/0.453
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.453
5a0112VO-glycosyltransferase/0.453
1d4lPI9Gag-Pol polyprotein3.4.23.160.452
1dw60Q4Gag-Pol polyprotein3.4.23.160.452
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.452
1rfvADPPyridoxal kinase2.7.1.350.452
1wbk568Pol protein/0.452
2bqvA1AProtease/0.452
2dsiSAHDiphthine synthase/0.452
2eh5SAHDiphthine synthase/0.452
2emrSAHDiphthine synthase/0.452
2fznFADBifunctional protein PutA1.5.5.20.452
2hr8SAHDiphthine synthase/0.452
2i4uDJRProtease/0.452
2ii6C5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.452
2owkSAHDiphthine synthase/0.452
2pb4SAHDiphthine synthase/0.452
2q641UNGag-Pol polyprotein3.4.23.160.452
2rlcCHDCholoylglycine hydrolase3.5.1.240.452
2wihP48Cyclin-dependent kinase 22.7.11.220.452
2xyeCXGGag-Pol polyprotein/0.452
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.452
3d20017Gag-Pol polyprotein3.4.23.160.452
3g5mFADRibosyldihydronicotinamide dehydrogenase [quinone]/0.452
3ggu017Gag-Pol polyprotein3.4.23.160.452
3h3t16HCollagen type IV alpha-3-binding protein/0.452
3ivgFG5Pantothenate synthetase6.3.2.10.452
3kfn3TLGag-Pol polyprotein/0.452
3l63CAMCamphor 5-monooxygenase1.14.15.10.452
3mxeK54Gag-Pol polyprotein3.4.23.160.452
3ty3GGGHomoisocitrate dehydrogenase1.1.1.870.452
3wrmCAMCamphor 5-monooxygenase1.14.15.10.452
4eb7PLPCysteine desulfurase IscS 2/0.452
4eu8COASuccinyl-CoA:acetate CoA-transferase/0.452
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.452
4q1w017Gag-Pol polyprotein3.4.23.160.452
1f20FADNitric oxide synthase, brain1.14.13.390.451
1fg62NCGag-Pol polyprotein3.4.23.160.451
1hviA77Protease/0.451
1n49RITGag-Pol polyprotein3.4.23.160.451
1nfbNADInosine-5'-monophosphate dehydrogenase 2/0.451
1owoFADDeoxyribodipyrimidine photo-lyase4.1.99.30.451
1qw514WNitric oxide synthase, inducible1.14.13.390.451
1vikBAYGag-Pol polyprotein/0.451
2af3COAPhosphate acetyltransferase2.3.1.80.451
2egsSAHDiphthine synthase/0.451
2ejzSAHDiphthine synthase/0.451
2ex1C5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.451
2gr0ADPFerredoxin reductase/0.451
2ijgFADCryptochrome DASH, chloroplastic/mitochondrial/0.451
2j08FADDeoxyribodipyrimidine photo-lyase4.1.99.30.451
2nmyROCProtease/0.451
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.451
2p5cSAHDiphthine synthase/0.451
2p5fSAHDiphthine synthase/0.451
2pcmSAHDiphthine synthase/0.451
2uxpCLMHTH-type transcriptional regulator TtgR/0.451
2yj5ATPCopper-transporting ATPase/0.451
2zvcSAHPrecorrin-3 C17-methyltransferase/0.451
3atrFDAConserved Archaeal protein/0.451
3dzvADPHydroxyethylthiazole kinase/0.451
3gvhNADMalate dehydrogenase/0.451
3h3qH13Collagen type IV alpha-3-binding protein/0.451
3nxe2NCProtease/0.451
3o9hK2EGag-Pol polyprotein/0.451
3oeeANPATP synthase subunit alpha, mitochondrial/0.451
3oeeANPATP synthase subunit beta, mitochondrial3.6.3.140.451
3ohh3HHBeta-secretase 13.4.23.460.451
3saa77FProtease/0.451
3vsxR32Renin3.4.23.150.451
3wycNAPMeso-diaminopimelate D-dehydrogenase1.4.1.160.451
4bfvZVVPantothenate kinase2.7.1.330.451
4d9m0JODiaminopropionate ammonia-lyase4.3.1.150.451
4fj2NAP17beta-hydroxysteroid dehydrogenase/0.451
4fn4NADShort chain dehydrogenase/0.451
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.451
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.451
4k4p3TLGag-Pol polyprotein/0.451
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.451
5hs1VORLanosterol 14-alpha demethylase/0.451
1guyNADMalate dehydrogenase/0.450
1mrwK57Gag-Pol polyprotein3.4.23.160.450
1n83CLRNuclear receptor ROR-alpha/0.450
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.450
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
1xl5190Gag-Pol polyprotein3.4.23.160.450
2c20NADUDP-glucose 4-epimerase/0.450
2ehuNAD1-pyrroline-5-carboxylate dehydrogenase/0.450
2i0dMUTProtease/0.450
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.450
2r8pT6FTransketolase 1/0.450
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
3adaNADSubunit alpha of sarocosine oxidase/0.450
3bbrBHYGlutamate receptor 2/0.450
3bnkFMNFlavoredoxin/0.450
3fwfCAMCamphor 5-monooxygenase1.14.15.10.450
3ggxGGXGag-Pol polyprotein/0.450
3in6FMNUncharacterized protein/0.450
3kfr3TLGag-Pol polyprotein/0.450
3mn6ATPActin-5C/0.450
3qrmNK7Gag-Pol polyprotein3.4.23.160.450
3qroNK9Gag-Pol polyprotein3.4.23.160.450
3sa323XProtease/0.450
3sj7NDP3-oxoacyl-(Acyl-carrier-protein) reductase, putative/0.450
3zptM8YGag-Pol polyprotein3.4.23.160.450
4cngSAHSpoU rRNA methylase/0.450
4hvh19RTyrosine-protein kinase JAK32.7.10.20.450
4kin1M8Mitogen-activated protein kinase 14/0.450
4oqyNDP(S)-imine reductase/0.450
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
7upjINUGag-Pol polyprotein3.4.23.160.450
1ajvNMBGag-Pol polyprotein3.4.23.160.449
1k74544Peroxisome proliferator-activated receptor gamma/0.449
1kp2ATPArgininosuccinate synthase6.3.4.50.449
1l4gNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.449
1omoNADAlanine dehydrogenase/0.449
1u80C5PCoenzyme A biosynthesis bifunctional protein CoaBC6.3.2.50.449
1vi2NADQuinate/shikimate dehydrogenase/0.449
2fxeDR7Gag-Pol polyprotein3.4.23.160.449
2gtbAZPOrf1ab polyprotein/0.449
2i4dQFIProtease/0.449
2qi1MZ4Gag-Pol polyprotein/0.449
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
3d91REMRenin3.4.23.150.449
3djjFADGlutathione reductase, mitochondrial1.8.1.70.449
3evcSAHGenome polyprotein2.1.1.560.449
3fwjCAMCamphor 5-monooxygenase1.14.15.10.449
3h3r14HCollagen type IV alpha-3-binding protein/0.449
3ictFADCoenzyme A disulfide reductase/0.449
3jvwDMPGag-Pol polyprotein3.4.23.160.449
3lzv017Gag-Pol polyprotein3.4.23.160.449
3nmpPYVAbscisic acid receptor PYL2/0.449
3ok9G52Gag-Pol polyprotein3.4.23.160.449
3pm1ETHTH-type transcriptional regulator QacR/0.449
3rh7FMNUncharacterized protein/0.449
3sa5A69Protease/0.449
3toh079Gag-Pol polyprotein2.7.7.490.449
4b1uLABActin, alpha skeletal muscle/0.449
4bcmT7ZCyclin-dependent kinase 22.7.11.220.449
4j5j478Gag-Pol polyprotein3.4.23.160.449
4lxm1YUBeta-secretase 13.4.23.460.449
4nifANPMitogen-activated protein kinase 12.7.11.240.449
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.449
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.449
5d3qGDPDynamin-13.6.5.50.449
1a8g2Z4Gag-Pol polyprotein3.4.23.160.448
1c6zROCProtease/0.448
1dr2TAPDihydrofolate reductase1.5.1.30.448
1geeNADGlucose 1-dehydrogenase1.1.1.470.448
1gilGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.448
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1kh3ANPArgininosuccinate synthase/0.448
1rdwLARActin, alpha skeletal muscle/0.448
1sguMK1Gag-Pol polyprotein3.4.23.160.448
1tj0FADBifunctional protein PutA1.5.5.20.448
1tllFMNNitric oxide synthase, brain1.14.13.390.448
1upjU01Gag-Pol polyprotein/0.448
2a1eIPFGag-Pol polyprotein3.4.23.160.448
2c9zQUEAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.448
2en5SAHDiphthine synthase/0.448
2gdzNAD15-hydroxyprostaglandin dehydrogenase [NAD(+)]1.1.1.1410.448
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
2owvSAHDiphthine synthase/0.448
2pym1UNGag-Pol polyprotein3.4.23.160.448
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.448
3dcrKVSProtease/0.448
3dv3MEKDual specificity mitogen-activated protein kinase kinase 12.7.12.20.448
3gbk2PQPeroxisome proliferator-activated receptor gamma/0.448
3isjA8DPantothenate synthetase6.3.2.10.448
3k5fAYHBeta-secretase 13.4.23.460.448
3mx2TTPNucleoprotein/0.448
3o0o5ADVitamin B12-dependent ribonucleotide reductase/0.448
3qzfX66Cyclin-dependent kinase 22.7.11.220.448
3udn09BBeta-secretase 13.4.23.460.448
3vswR31Renin3.4.23.150.448
4ef4C2EStimulator of interferon genes protein/0.448
4gkvNADAlcohol dehydrogenase, propanol-preferring1.1.1.10.448
4hegG52Gag-Pol polyprotein3.4.23.160.448
4jc51K5Stimulator of interferon genes protein/0.448
4mcb21WtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.448
1bv7XV6Gag-Pol polyprotein3.4.23.160.447
1ebk0Q4Gag-Pol polyprotein3.4.23.160.447
1fg80Q4Gag-Pol polyprotein3.4.23.160.447
1fvv107Cyclin-dependent kinase 22.7.11.220.447
1izhQ50Protease/0.447
1msnJE2Gag-Pol polyprotein3.4.23.160.447
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.447
1owmFADDeoxyribodipyrimidine photo-lyase4.1.99.30.447
1rbmKT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.447
1sm2STUTyrosine-protein kinase ITK/TSK2.7.10.20.447
1u3cFADCryptochrome-1/0.447
1vbiNADMalate/L-lactate dehydrogenase family protein/0.447
1yqxNAPSinapyl alcohol dehydrogenase/0.447
2bt4CA23-dehydroquinate dehydratase4.2.1.100.447
2ep7NADGlyceraldehyde-3-phosphate dehydrogenase/0.447
2g1n1IGRenin3.4.23.150.447
2hfuMEVMevalonate kinase/0.447
2ovhAS0Progesterone receptor/0.447
2p6lSAHDiphthine synthase/0.447
2p9dSAHDiphthine synthase/0.447
2pcaSAHDiphthine synthase/0.447
2ph6712Beta-secretase 13.4.23.460.447
2x1nX1NCyclin-dependent kinase 22.7.11.220.447
2zgzGNPPlasmid segregation protein ParM/0.447
3b05FNRIsopentenyl-diphosphate delta-isomerase/0.447
3d1z017Gag-Pol polyprotein3.4.23.160.447
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.447
3ekyDR7Gag-Pol polyprotein3.4.23.160.447
3lxiCAMCytochrome P450/0.447
3nls016Gag-Pol polyprotein3.4.23.160.447
3pw8ACO1,2-phenylacetyl-CoA epoxidase, subunit A1.14.13.1490.447
3s56ROCProtease/0.447
3wrhCAMCamphor 5-monooxygenase1.14.15.10.447
4b4vL34Bifunctional protein FolD/0.447
4ccqFADThioredoxin reductase/0.447
4egbNADdTDP-glucose 4,6-dehydratase/0.447
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.447
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
4njt017Protease/0.447
4opgFDAConserved Archaeal protein/0.447
5a1tNAIL-lactate dehydrogenase/0.447
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
1bil0IURenin3.4.23.150.446
1bx6BA1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
1dhrNADDihydropteridine reductase1.5.1.340.446
1g2kNM1Gag-Pol polyprotein3.4.23.160.446
1gv0NADMalate dehydrogenase/0.446
1iqrFADDeoxyribodipyrimidine photo-lyase4.1.99.30.446
1ja1FMNNADPH--cytochrome P450 reductase/0.446
1sdtMK1Gag-Pol polyprotein3.4.23.160.446
1u28NAPNAD(P) transhydrogenase subunit beta1.6.1.20.446
1w5xBE5Gag-Pol polyprotein3.4.23.160.446
2a92NAIL-lactate dehydrogenase/0.446
2bpv1INGag-Pol polyprotein3.4.23.160.446
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.446
2dxiATPGlutamate--tRNA ligase6.1.1.170.446
2ek3SAHDiphthine synthase/0.446
2fxdDR7Pol polyprotein/0.446
2g9rG27Glycogen phosphorylase, muscle form2.4.1.10.446
2p2jPRXAcetyl-coenzyme A synthetase/0.446
2p3d3TLProtease/0.446
2uxhQUEHTH-type transcriptional regulator TtgR/0.446
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.446
3iocA5DPantothenate synthetase6.3.2.10.446
3kddJZQGag-Pol polyprotein3.4.23.160.446
3ms421NGlycogen phosphorylase, muscle form2.4.1.10.446
3mws017Pol protein/0.446
3te4ACODopamine N-acetyltransferase/0.446
3zh8C58Protein kinase C iota type2.7.11.130.446
4fx360KCyclin-dependent kinase 22.7.11.220.446
4lopSB4Mitogen-activated protein kinase 14/0.446
4wloNAIMalate dehydrogenase, mitochondrial1.1.1.370.446
5eb5FAD(R)-mandelonitrile lyase 14.1.2.100.446
1drhNAPDihydrofolate reductase1.5.1.30.445
1eagA70Candidapepsin-23.4.23.240.445
1ec2BEJGag-Pol polyprotein3.4.23.160.445
1fy7COAHistone acetyltransferase ESA1/0.445
1hxwRITGag-Pol polyprotein/0.445
1i9c5ADGlutamate mutase epsilon subunit/0.445
1j1bANPGlycogen synthase kinase-3 beta2.7.11.260.445
1la2NADInositol-3-phosphate synthase5.5.1.40.445
1odw0E8Gag-Pol polyprotein3.4.23.160.445
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.445
1uamSAHtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.445
1zemNADXylitol dehydrogenase/0.445
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
2b4yAPRNAD-dependent protein deacylase sirtuin-5, mitochondrial/0.445
2cen4AHProtease/0.445
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.445
2ek2SAHDiphthine synthase/0.445
2gciMRRProbable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.445
2p3a3TLPol protein/0.445
2q7vFADThioredoxin reductase/0.445
2qs4LY5Glutamate receptor ionotropic, kainate 1/0.445
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2v7a627Tyrosine-protein kinase ABL12.7.10.20.445
2webPP4Penicillopepsin-13.4.23.200.445
2yj4ATPCopper-transporting ATPase/0.445
2zryFNRIsopentenyl-diphosphate delta-isomerase/0.445
2zvbSAHPrecorrin-3 C17-methyltransferase/0.445
3el9DR7Gag-Pol polyprotein3.4.23.160.445
3hzc2NCProtease/0.445
3imeBZ2Pantothenate synthetase6.3.2.10.445
3o0qADNVitamin B12-dependent ribonucleotide reductase/0.445
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.445
3otfCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.445
3owaFADAcyl-CoA dehydrogenase/0.445
3oxv478Gag-Pol polyprotein3.4.23.160.445
3r9uFADThioredoxin reductase/0.445
3t113T1Gag-Pol polyprotein3.4.23.160.445
3w233RODihydroorotate dehydrogenase (fumarate)1.3.98.10.445
3w2jQRODihydroorotate dehydrogenase (fumarate)1.3.98.10.445
4aacAAVMitogen-activated protein kinase 14/0.445
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.445
4dt9GMPAPH(2'')-Id/0.445
4ekeD1IGlycogen phosphorylase, muscle form2.4.1.10.445
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.445
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.445
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.445
1cf3FADGlucose oxidase1.1.3.40.444
1dgmADNAdenosine kinase2.7.1.200.444
1i6lTYMTryptophan--tRNA ligase6.1.1.20.444
1m9rINENitric oxide synthase, endothelial1.14.13.390.444
1s20NAD2,3-diketo-L-gulonate reductase1.1.1.1300.444
1yobFMNFlavodoxin 2/0.444
2b4rNADGlyceraldehyde-3-phosphate dehydrogenase/0.444
2ekaSAHDiphthine synthase/0.444
2eldSAHDiphthine synthase/0.444
2eniSAHDiphthine synthase/0.444
2g21L1BRenin3.4.23.150.444
2huvSAHDiphthine synthase/0.444
2pyn1UNGag-Pol polyprotein3.4.23.160.444
2q2vNADBeta-D-hydroxybutyrate dehydrogenase/0.444
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.444
2xx91NFGlutamate receptor 2/0.444
2znnS44Peroxisome proliferator-activated receptor alpha/0.444
3akzGSUGlutamate--tRNA ligase 2/0.444
3bheBZNGag-Pol polyprotein3.4.23.160.444
3bl7DD1m7GpppX diphosphatase3.6.1.590.444
3ekqROCGag-Pol polyprotein3.4.23.160.444
3f8rNAPNADH oxidase/thioredoxin reductase/0.444
3gi4K60Gag-Pol polyprotein/0.444
3gyeFMNDihydroorotate dehydrogenase (fumarate)/0.444
3i25MV7Beta-secretase 13.4.23.460.444
3ingNDPHomoserine dehydrogenase related protein/0.444
3oqkS52Renin3.4.23.150.444
3p84FMNPentaerythritol tetranitrate reductase/0.444
3sa6F71Protease/0.444
4a6cQG9Gag-Pol polyprotein3.4.23.160.444
4acxS8ZBeta-secretase 13.4.23.460.444
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.444
5cypGSPSeptin-9/0.444
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.444
5jydNADShort chain dehydrogenase/0.444
1c2tNHSPhosphoribosylglycinamide formyltransferase/0.443
1lf3EH5Plasmepsin-23.4.23.390.443
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.443
1nyxDRFPeroxisome proliferator-activated receptor gamma/0.443
1w0kADPATP synthase subunit alpha, mitochondrial/0.443
1w0kADPATP synthase subunit beta, mitochondrial3.6.3.140.443
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.443
2d2iNAPGlyceraldehyde-3-phosphate dehydrogenase/0.443
2dxxSAHDiphthine synthase/0.443
2e17SAHDiphthine synthase/0.443
2eeqSAHDiphthine synthase/0.443
2fdd385Pol protein/0.443
2gmjFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.443
2izrBRKCasein kinase I isoform gamma-32.7.11.10.443
2m56CAMCamphor 5-monooxygenase1.14.15.10.443
2ohjFMNType A flavoprotein FprA10.443
2qdxFADFerredoxin--NADP+ reductase/0.443
2qi5MZ7Gag-Pol polyprotein/0.443
2uw4L15cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
3a28NADL-2,3-butanediol dehydrogenase1.1.1.760.443
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.443
3ig6438Urokinase-type plasminogen activator3.4.21.730.443
3pmy41LEndothiapepsin3.4.23.220.443
3q5dGDPAtlastin-13.6.50.443
3w3oROEDihydroorotate dehydrogenase (fumarate)1.3.98.10.443
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.443
3zxiTYATyrosine--tRNA ligase, mitochondrial6.1.1.10.443
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4ctjSAMGenome polyprotein/0.443
4dh60KNBeta-secretase 13.4.23.460.443
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.443
4h3zSAHtRNA (guanine-N(1)-)-methyltransferase/0.443
4k81GTPGTPase HRas/0.443
4kb81QOCasein kinase I isoform delta2.7.11.10.443
4m83ERYOleandomycin glycosyltransferase2.4.10.443
4qmzB49Serine/threonine-protein kinase 242.7.11.10.443
4qq3XMPInosine-5'-monophosphate dehydrogenase/0.443
5c1mCLRMu-type opioid receptor/0.443
1daz0Q4Gag-Pol polyprotein3.4.23.160.442
1ff02NCGag-Pol polyprotein3.4.23.160.442
1idb0DOGag-Pol polyprotein/0.442
1jhrP2PNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.442
1n77ATPGlutamate--tRNA ligase6.1.1.170.442
1qvrANPChaperone protein ClpB/0.442
1tcwIM1Gag-Pol polyprotein/0.442
1u2yGOXPancreatic alpha-amylase/0.442
1uayADNOxidoreductase/0.442
1v9aSAHUncharacterized protein/0.442
1xagNAD3-dehydroquinate synthase/0.442
1yrdCAMCamphor 5-monooxygenase1.14.15.10.442
2c6lDT4Cyclin-dependent kinase 22.7.11.220.442
2ewvADPTwitching motility protein PilT/0.442
2hldANPATP synthase subunit alpha, mitochondrial/0.442
2hldANPATP synthase subunit beta, mitochondrial3.6.3.140.442
2i3gNAPN-acetyl-gamma-glutamyl-phosphate reductase1.2.1.380.442
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.442
2qi0MZ3Gag-Pol polyprotein/0.442
2rhgIGPTryptophan synthase alpha chain/0.442
2uy0HV1Gag-Pol polyprotein3.4.23.160.442
2w3bNDPDihydrofolate reductase1.5.1.30.442
3bmoNAPPteridine reductase/0.442
3btjDEQHTH-type transcriptional regulator QacR/0.442
3cinNADMyo-inositol-1-phosphate synthase-related protein/0.442
3d1xROCGag-Pol polyprotein3.4.23.160.442
3eah327Nitric oxide synthase, endothelial1.14.13.390.442
3gwdNAPCyclohexanone monooxygenase/0.442
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.442
3imgBZ3Pantothenate synthetase6.3.2.10.442
3ivxFG6Pantothenate synthetase6.3.2.10.442
3mk6ACOPantothenate kinase 32.7.1.330.442
3nux3NVCyclin-dependent kinase 62.7.11.220.442
3nynSGVG protein-coupled receptor kinase 62.7.11.160.442
3qt62P0Mevalonate diphosphate decarboxylase/0.442
3sa755AProtease/0.442
3sdi3SDProteasome subunit beta type-53.4.25.10.442
3sdi3SDProteasome subunit beta type-63.4.25.10.442
3wrjCAMCamphor 5-monooxygenase1.14.15.10.442
4cfaWOPIntegrase/0.442
4eb5PLPCysteine desulfurase IscS 2/0.442
4fk8FADFerredoxin--NADP reductase/0.442
4kkyCAMCamphor 5-monooxygenase1.14.15.10.442
4o8aFADBifunctional protein PutA1.2.1.880.442
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
4s26SAHPhosphomethylpyrimidine synthase, chloroplastic4.1.99.170.442
5ej5TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.442
1a8pFADFerredoxin--NADP reductase/0.441
1b5eDCMDeoxycytidylate 5-hydroxymethyltransferase2.1.2.80.441
1cdeDZFPhosphoribosylglycinamide formyltransferase/0.441
1d4iBEGGag-Pol polyprotein3.4.23.160.441
1hxbROCGag-Pol polyprotein3.4.23.160.441
1mjaCOAHistone acetyltransferase ESA1/0.441
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.441
1tu3GNPRas-related protein Rab-5A/0.441
1u33LM2Pancreatic alpha-amylase/0.441
2aa3AP0L-lactate dehydrogenase/0.441
2emuSAHDiphthine synthase/0.441
2gjlFMNNitronate monooxygenase1.13.12.160.441
2hs1017Protease/0.441
2ikuLIYRenin3.4.23.150.441
2owgSAHDiphthine synthase/0.441
2psvMUVProtease/0.441
2rbeZMGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
2v3aFADRubredoxin-NAD(+) reductase1.18.1.10.441
2vci2GJHeat shock protein HSP 90-alpha/0.441
2vesGVRUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.441
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.441
2xlrFADPutative flavin-containing monooxygenase/0.441
2xtnGTPGTPase IMAP family member 2/0.441
3ad9NADSubunit alpha of sarocosine oxidase/0.441
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.441
3dds26BGlycogen phosphorylase, liver form2.4.1.10.441
3elySAHMethyltransferase/0.441
3fpzAHZThiamine thiazole synthase/0.441
3livE16Protease/0.441
3oibFDAPutative acyl-CoA dehydrogenase/0.441
3orfNADDihydropteridine reductase1.5.1.340.441
3own3OWRenin3.4.23.150.441
3pwrROCGag-Pol polyprotein3.4.23.160.441
3q5lKX2Heat shock protein 83-1/0.441
3qgf46FGenome polyprotein2.7.7.480.441
3rtnRTNBeta-secretase 13.4.23.460.441
3t6iNC9Endothiapepsin3.4.23.220.441
3ulkNDPKetol-acid reductoisomerase (NADP(+))/0.441
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.441
3vf30GSBeta-secretase 13.4.23.460.441
4a6nFADTetX family tetracycline inactivation enzyme/0.441
4b68FADL-ornithine N(5)-monooxygenase/0.441
4c0bATPmRNA cleavage and polyadenylation factor CLP1/0.441
4cczTHGMethionine synthase2.1.1.130.441
4cdmFADDeoxyribodipyrimidine photolyase/0.441
4jhz1KVBeta-glucuronidase3.2.1.310.441
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.441
4njsG08Protease/0.441
4opdFDAConserved Archaeal protein/0.441
4opuFDAConserved Archaeal protein/0.441
5ej9TPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.441
1bygSTUTyrosine-protein kinase CSK/0.440
1d4hBEHGag-Pol polyprotein3.4.23.160.440
1dr5NAPDihydrofolate reductase1.5.1.30.440
1ec0BEDGag-Pol polyprotein3.4.23.160.440
1hihC20Gag-Pol polyprotein/0.440
1hvlA76Gag-Pol polyprotein/0.440
1jld0PPGag-Pol polyprotein/0.440
1kzkJE2Gag-Pol polyprotein3.4.23.160.440
1l4mNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.440
1rl8RITGag-Pol polyprotein3.4.23.160.440
1sbgIM1Gag-Pol polyprotein/0.440
1xduSFGAclacinomycin 10-hydroxylase RdmB4.1.10.440
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
2a5kAZPReplicase polyprotein 1ab3.4.220.440
2b3vACODiamine acetyltransferase 1/0.440
2bsmBSMHeat shock protein HSP 90-alpha/0.440
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.440
2dshSAHDiphthine synthase/0.440
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.440
2ieo017Protease/0.440
2p6kSAHDiphthine synthase/0.440
2qak1UNGag-Pol polyprotein3.4.23.160.440
2tmdADPTrimethylamine dehydrogenase1.5.8.20.440
3ecg065Gag-Pol polyprotein3.4.23.470.440
3friSAH16S rRNA methylase/0.440
3gonANPPhosphomevalonate kinase/0.440
3nwxKVSGag-Pol polyprotein3.4.23.160.440
3o9eA60Pol polyprotein/0.440
3od0PCGcGMP-dependent protein kinase 12.7.11.120.440
3oxxDR7Gag-Pol polyprotein3.4.23.160.440
3so9017Pol protein/0.440
3tof076Gag-Pol polyprotein2.7.7.490.440
3vx4ATPPutative ABC transporter, ATP-binding protein ComA/0.440
3zdiUGJGlycogen synthase kinase-3 beta2.7.11.260.440
4c4oNADSADH/0.440
4du82P0Mevalonate diphosphate decarboxylase/0.440
4f081RSTyrosine-protein kinase JAK2/0.440
4f650S9Fibroblast growth factor receptor 1/0.440
4fv6E57Mitogen-activated protein kinase 12.7.11.240.440
4hi0GDPUrease accessory protein UreG/0.440
4hla017Gag-Pol polyprotein3.4.23.160.440
4l435FIRibosomal protein S6 kinase beta-12.7.11.10.440
4ne0ZZUHydroxylase/0.440
4o5uFADAlkyl hydroperoxide reductase subunit F1.8.10.440
4px9ADPATP-dependent RNA helicase DDX3X3.6.4.130.440
4y3jHICEndothiapepsin3.4.23.220.440
4z4pSAHHistone-lysine N-methyltransferase 2D2.1.1.430.440
5e7oMD1DMSO reductase family type II enzyme, molybdopterin subunit/0.440