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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3o7lANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3o7lANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
4iacACPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.564
3x2wATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.554
3x2uATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.536
4xw4ANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.536
3idbANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.535
3x2vATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.499
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.497
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.492
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.487
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.484
3idcANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.482
4iakADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.480
4wbbADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.479
4iazADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.478
4qnyANPMitogen activated protein kinase, putative/0.476
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.475
4ekkANPRAC-alpha serine/threonine-protein kinase2.7.11.10.471
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.468
4ysjADPCalmodulin-like domain protein kinase/0.467
4dg3ANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
1ig1ANPDeath-associated protein kinase 12.7.11.10.463
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
4i3zADPCyclin-dependent kinase 22.7.11.220.460
4dh5ADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
1qmzATPCyclin-dependent kinase 22.7.11.220.450
3c4zADPRhodopsin kinase/0.448
4iayADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
4ocgCOAFAD-dependent pyridine nucleotide-disulphide oxidoreductase/0.446
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.445
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2xb5I7TTetracycline repressor protein class D/0.444
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442