Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3o7bSAHRibosomal RNA small subunit methyltransferase Nep1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3o7bSAHRibosomal RNA small subunit methyltransferase Nep1/1.000
1xe55FEPlasmepsin-23.4.23.390.525
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.523
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.517
2iyfERYOleandomycin glycosyltransferase2.4.10.504
3p82FMNPentaerythritol tetranitrate reductase/0.499
3bbhSFGRibosomal RNA small subunit methyltransferase Nep12.1.10.497
4kbyC2EStimulator of interferon genes protein/0.497
2gv8NDPThiol-specific monooxygenase1.14.130.495
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.493
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.493
1kp3ATPArgininosuccinate synthase6.3.4.50.492
3bbdSAHRibosomal RNA small subunit methyltransferase Nep12.1.10.492
3f03FMNPentaerythritol tetranitrate reductase/0.492
3ty3GGGHomoisocitrate dehydrogenase1.1.1.870.490
2il2LIXRenin3.4.23.150.489
4v2gITCTetracycline repressor protein class D/0.489
1h51FMNPentaerythritol tetranitrate reductase/0.488
5d3qGDPDynamin-13.6.5.50.488
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.488
2rlcCHDCholoylglycine hydrolase3.5.1.240.486
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.484
3atzFMNProstaglandin F2a synthase/0.483
2zvbSAHPrecorrin-3 C17-methyltransferase/0.482
3hlwCE3Beta-lactamase/0.482
3o0o5ADVitamin B12-dependent ribonucleotide reductase/0.482
2gz7D3FOrf1a polyprotein/0.481
3q43D66M1 family aminopeptidase3.4.110.480
1kh3ANPArgininosuccinate synthase/0.479
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.479
1x1aSAMC-20 methyltransferase/0.479
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.479
3nutSAHPrecorrin-3 methylase/0.479
4ef4C2EStimulator of interferon genes protein/0.479
2g1s4IGRenin3.4.23.150.478
3ai3NDPNADPH-sorbose reductase/0.478
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.478
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.478
4m83ERYOleandomycin glycosyltransferase2.4.10.478
1bil0IURenin3.4.23.150.477
2pb4SAHDiphthine synthase/0.477
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.477
4xboSAHtRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ2.1.1.2000.477
1bwsNDPGDP-L-fucose synthase/0.476
1ikiREYD-alanyl-D-alanine carboxypeptidase3.4.16.40.475
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.475
3h06VBPGlutamate receptor 2/0.475
4tqgNDPPutative dTDP-d-glucose 4 6-dehydratase/0.475
2g1n1IGRenin3.4.23.150.474
2yd0BESEndoplasmic reticulum aminopeptidase 13.4.110.474
2zvcSAHPrecorrin-3 C17-methyltransferase/0.474
3p62FMNPentaerythritol tetranitrate reductase/0.474
2g1y5IGRenin3.4.23.150.473
2v16C47Renin3.4.23.150.473
4gddNAIUDP-galactopyranose mutase/0.473
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.473
1udaUFGUDP-glucose 4-epimerase5.1.3.20.472
2dftADPShikimate kinase2.7.1.710.472
3kkzSAMUncharacterized protein/0.472
1ohhANPATP synthase subunit alpha, mitochondrial/0.471
1ohhANPATP synthase subunit beta, mitochondrial3.6.3.140.471
4j4nD44Peptidylprolyl isomerase/0.471
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.471
1cnfFADNitrate reductase [NADH]1.7.1.10.470
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.470
2ilvC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.470
3i25MV7Beta-secretase 13.4.23.460.470
1h50FMNPentaerythritol tetranitrate reductase/0.469
1nzdUPGDNA beta-glucosyltransferase/0.469
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
4eb7PLPCysteine desulfurase IscS 2/0.469
1icqFMN12-oxophytodienoate reductase 11.3.1.420.468
2y1tDUDSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.468
4kgnSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.468
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.467
1xvaSAMGlycine N-methyltransferase2.1.1.200.467
2bjfDXCCholoylglycine hydrolase3.5.1.240.467
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.467
3ziuLSSLeucyl-tRNA synthetase/0.467
4r81FMNPredicted NADH dehydrogenase/0.467
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.466
2p6kSAHDiphthine synthase/0.466
3akzGSUGlutamate--tRNA ligase 2/0.466
4bf9FMNtRNA-dihydrouridine(16) synthase/0.466
1rzuADPGlycogen synthase 12.4.1.210.465
2gjlFMNNitronate monooxygenase1.13.12.160.465
2i3gNAPN-acetyl-gamma-glutamyl-phosphate reductase1.2.1.380.465
3a3gDLZLumazine protein/0.465
3tjzGNPADP-ribosylation factor 1/0.465
3zcnATPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.465
4jicFMNGTN Reductase/0.465
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.464
1psa0ZLPepsin A3.4.23.10.464
3nsh957Beta-secretase 13.4.23.460.464
4i0i957Beta-secretase 13.4.23.460.464
4jayNAPUDP-N-acetylenolpyruvoylglucosamine reductase/0.464
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.464
5c1d12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.464
1rneC60Renin3.4.23.150.463
2dxwSAHDiphthine synthase/0.463
2ed5SAHDiphthine synthase/0.463
2g20L1ARenin3.4.23.150.463
3b70NAPEnoyl reductase LovC10.463
3rufNADUDP-N-acetylglucosamine 4-epimerase/0.463
3s2v3HUGlutamate receptor ionotropic, kainate 1/0.463
3tr05GPGuanylate kinase/0.463
3ukoNADAlcohol dehydrogenase class-3/0.463
4dx7DM2Multidrug efflux pump subunit AcrB/0.463
4qxr1YEStimulator of interferon genes protein/0.463
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.462
3k5fAYHBeta-secretase 13.4.23.460.462
3o0qADNVitamin B12-dependent ribonucleotide reductase/0.462
3p67FMNPentaerythritol tetranitrate reductase/0.462
4bfzZVZPantothenate kinase2.7.1.330.462
4f5yC2EStimulator of interferon genes protein/0.462
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.462
1f8wFADNADH peroxidase1.11.1.10.461
1h73ANPHomoserine kinase2.7.1.390.461
1vyrFMNPentaerythritol tetranitrate reductase/0.461
1w34FADFerredoxin--NADP reductase1.18.1.20.461
2a5kAZPReplicase polyprotein 1ab3.4.220.461
2e16SAHDiphthine synthase/0.461
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.461
3bk2U5PRibonuclease J/0.461
3h6vNS6Glutamate receptor 2/0.461
3p74FMNPentaerythritol tetranitrate reductase/0.461
3qe2FMNNADPH--cytochrome P450 reductase/0.461
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.461
4egbNADdTDP-glucose 4,6-dehydratase/0.461
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.460
1l7x700Glycogen phosphorylase, liver form2.4.1.10.460
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.460
2b53D23Cyclin-dependent kinase 22.7.11.220.460
2i4qUA4Renin3.4.23.150.460
2ii6C5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.460
2xfiXFIBeta-secretase 13.4.23.460.460
3axkNDPRibulose bisphosphate carboxylase large chain4.1.1.390.460
4df2FMNNADPH dehydrogenase/0.460
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.460
1qrpHH0Pepsin A-43.4.23.10.459
1xe65FPPlasmepsin-23.4.23.390.459
2ejkSAHDiphthine synthase/0.459
3hl0NADMaleylacetate reductase/0.459
3qt62P0Mevalonate diphosphate decarboxylase/0.459
3s1dZIRCytokinin dehydrogenase 11.5.99.120.459
3vsxR32Renin3.4.23.150.459
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.459
4wecNADShort chain dehydrogenase/0.459
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.459
2egsSAHDiphthine synthase/0.458
2g1r3IGRenin3.4.23.150.458
2g247IGRenin3.4.23.150.458
2hs6FMN12-oxophytodienoate reductase 31.3.1.420.458
2pcaSAHDiphthine synthase/0.458
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.458
3m2uCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.458
3rfaSAMDual-specificity RNA methyltransferase RlmN/0.458
4k6fNAPPutative Acetoacetyl-CoA reductase/0.458
4lutDCSAlanine racemase/0.458
1bim0QBRenin3.4.23.150.457
1kp2ATPArgininosuccinate synthase6.3.4.50.457
1lf2R37Plasmepsin-23.4.23.390.457
2b58COADiamine acetyltransferase 1/0.457
3q9bB3NAcetylpolyamine amidohydrolase/0.457
4lol1YEStimulator of interferon genes protein/0.457
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
1owe675Urokinase-type plasminogen activator3.4.21.730.456
2xuoTZ4Acetylcholinesterase3.1.1.70.456
3bj8COADiamine acetyltransferase 1/0.456
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.456
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.456
1g63FMNEpidermin decarboxylase4.1.10.455
1vjiFMN12-oxophytodienoate reductase 11.3.1.420.455
2dxvSAHDiphthine synthase/0.455
2ek7SAHDiphthine synthase/0.455
3udk095Beta-secretase 13.4.23.460.455
3wycNAPMeso-diaminopimelate D-dehydrogenase1.4.1.160.455
4a862ANMajor pollen allergen Bet v 1-A/0.455
4e2xTYDMethyltransferase/0.455
4emdC5P4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.455
4ewo996Beta-secretase 13.4.23.460.455
4gdcNDPUDP-galactopyranose mutase/0.455
1cs4FOKAdenylate cyclase type 2/0.454
1cs4FOKAdenylate cyclase type 5/0.454
1egeFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.454
1fcbFMNCytochrome b2, mitochondrial1.1.2.30.454
1icsFMN12-oxophytodienoate reductase 11.3.1.420.454
1kfbIGPTryptophan synthase alpha chain/0.454
1o76CAMCamphor 5-monooxygenase1.14.15.10.454
2e8qSAHDiphthine synthase/0.454
2en5SAHDiphthine synthase/0.454
2owgSAHDiphthine synthase/0.454
2pj4414Carboxypeptidase B/0.454
2pncCLUPrimary amine oxidase, liver isozyme/0.454
2rcyNAPPyrroline-5-carboxylate reductase/0.454
3d91REMRenin3.4.23.150.454
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.454
3imgBZ2Pantothenate synthetase6.3.2.10.454
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.454
3w233RODihydroorotate dehydrogenase (fumarate)1.3.98.10.454
4g3jVNTLanosterol 14-alpha-demethylase/0.454
4jnkNAIL-lactate dehydrogenase A chain1.1.1.270.454
4loi1YCStimulator of interferon genes protein/0.454
4mo2FADUDP-galactopyranose mutase/0.454
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.453
1ra3NAPDihydrofolate reductase1.5.1.30.453
1tcoFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.453
1tcoFK5Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform3.1.3.160.453
1w6hTITPlasmepsin-23.4.23.390.453
2a94AP0L-lactate dehydrogenase1.1.1.270.453
2fj1CTCTetracycline repressor protein class D/0.453
2g1o2IGRenin3.4.23.150.453
2ph6712Beta-secretase 13.4.23.460.453
2vkmBSDBeta-secretase 13.4.23.460.453
3gqvNAPEnoyl reductase LovC10.453
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.453
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.453
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.453
4j75TYMTryptophan--tRNA ligase/0.453
4ke11R6Beta-secretase 13.4.23.460.453
1bsvNDPGDP-L-fucose synthase/0.452
1g1aNADdTDP-glucose 4,6-dehydratase/0.452
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.452
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.452
1x1dSAHC-20 methyltransferase/0.452
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.452
2dsiSAHDiphthine synthase/0.452
2egbSAHDiphthine synthase/0.452
2g226IGRenin3.4.23.150.452
2hizLIJBeta-secretase 13.4.23.460.452
2hs8FMN12-oxophytodienoate reductase 31.3.1.420.452
2iko7IGRenin3.4.23.150.452
2is0I03Beta-secretase 13.4.23.460.452
2nnqT4BFatty acid-binding protein, adipocyte/0.452
2vyqFADFerredoxin--NADP reductase1.18.1.20.452
3aho3A2Oligopeptidase/0.452
3isjA8DPantothenate synthetase6.3.2.10.452
3k5c0BIBeta-secretase 13.4.23.460.452
3oafOAGDihydrofolate reductase1.5.1.30.452
3sxjSAMPutative methyltransferase/0.452
3vg10GTBeta-secretase 13.4.23.460.452
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.452
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.452
5a0112VO-glycosyltransferase/0.452
2c20NADUDP-glucose 4-epimerase/0.451
2cftPLPPyridoxal phosphate phosphatase/0.451
2eh5SAHDiphthine synthase/0.451
2el0SAHDiphthine synthase/0.451
2oapANPType II secretion system protein (GspE-2)/0.451
2p9dSAHDiphthine synthase/0.451
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.451
3e32ED2Protein farnesyltransferase subunit beta2.5.1.580.451
3fr5I4AFatty acid-binding protein, adipocyte/0.451
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.451
3lpjZ75Beta-secretase 13.4.23.460.451
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.451
4bfvZVVPantothenate kinase2.7.1.330.451
4qxq1YEStimulator of interferon genes protein/0.451
4xguADPPutative pachytene checkpoint protein 2/0.451
5cflC2EStimulator of interferon genes protein/0.451
1beuIPLTryptophan synthase alpha chain/0.450
1dj2GDPAdenylosuccinate synthetase, chloroplastic/0.450
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.450
1h63FMNPentaerythritol tetranitrate reductase/0.450
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
2ck3ANPATP synthase subunit alpha, mitochondrial/0.450
2ck3ANPATP synthase subunit beta, mitochondrial3.6.3.140.450
2huvSAHDiphthine synthase/0.450
2owfSAHDiphthine synthase/0.450
2x06NADL-sulfolactate dehydrogenase/0.450
2xx91NFGlutamate receptor 2/0.450
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
4f9gC2EStimulator of interferon genes protein/0.450
4pzkSAHPutative tRNA (cytidine(34)-2'-O)-methyltransferase/0.450
4tmbFMNOld yellow enzyme/0.450
4u3jGTPTubulin beta chain/0.450
4z4pSAHHistone-lysine N-methyltransferase 2D2.1.1.430.450
1f20FADNitric oxide synthase, brain1.14.13.390.449
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.449
1w0kADPATP synthase subunit alpha, mitochondrial/0.449
1w0kADPATP synthase subunit beta, mitochondrial3.6.3.140.449
2dvlFADAcyl-CoA dehydrogenase/0.449
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.449
2he5NDPAldo-keto reductase family 1 member C211.1.10.449
2rh9IGPTryptophan synthase alpha chain/0.449
2wf1ZY1Beta-secretase 13.4.23.460.449
2whqHI6Acetylcholinesterase3.1.1.70.449
2wu4HBPAcetylcholinesterase3.1.1.70.449
3ibqATPPyridoxal kinase/0.449
3imeBZ2Pantothenate synthetase6.3.2.10.449
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.449
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.449
3w1qYRODihydroorotate dehydrogenase (fumarate)1.3.98.10.449
4b63FADL-ornithine N(5)-monooxygenase/0.449
4dbzNDPPutative ketoacyl reductase1.3.10.449
4dd8BATDisintegrin and metalloproteinase domain-containing protein 83.4.240.449
4jc51K5Stimulator of interferon genes protein/0.449
5hynSAHHistone-lysine N-methyltransferase EZH22.1.1.430.449
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
1ee9NADMethylenetetrahydrofolate dehydrogenase [NAD(+)]1.5.1.150.448
1lbcCYZGlutamate receptor 2/0.448
1x1bSAHC-20 methyltransferase/0.448
2dsgSAHDiphthine synthase/0.448
2dv4SAHDiphthine synthase/0.448
2eglSAHDiphthine synthase/0.448
2emrSAHDiphthine synthase/0.448
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.448
2qbmCAMCamphor 5-monooxygenase1.14.15.10.448
3bbrBHYGlutamate receptor 2/0.448
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.448
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.448
4b65FADL-ornithine N(5)-monooxygenase/0.448
4de3DN8Beta-lactamase/0.448
4m5pFMNNADPH dehydrogenase/0.448
5bnw12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.448
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1l5s700Glycogen phosphorylase, liver form2.4.1.10.447
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.447
1umkFADNADH-cytochrome b5 reductase 31.6.2.20.447
2abbFMNPentaerythritol tetranitrate reductase/0.447
2e4nSAHDiphthine synthase/0.447
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.447
3zhbNAPPutative dehydrogenase/0.447
4b1c1B1Beta-secretase 13.4.23.460.447
4b79NADProbable short-chain dehydrogenase/0.447
4bb3KKAIsopenicillin N synthase1.21.3.10.447
4dmmNAP3-oxoacyl-[acyl-carrier-protein] reductase/0.447
4eb5PLPCysteine desulfurase IscS 2/0.447
4fco0U4Beta-secretase 13.4.23.460.447
4g7gVFVLanosterol 14-alpha-demethylase/0.447
4m9aFDAAcyl-CoA dehydrogenase/0.447
6ctsCICCitrate synthase, mitochondrial2.3.3.10.447
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.446
1i5eU5PUracil phosphoribosyltransferase/0.446
1kevNDPNADP-dependent isopropanol dehydrogenase1.1.1.800.446
2e8sSAHDiphthine synthase/0.446
2ntrL00Beta-secretase 13.4.23.460.446
2pb5SAHDiphthine synthase/0.446
3f63GTXGlutathione transferase GST1-4/0.446
3ruaNADUDP-N-acetylglucosamine 4-epimerase/0.446
4euaCOASuccinyl-CoA:acetate CoA-transferase/0.446
5cc9DDFDihydrofolate reductase1.5.1.30.446
5dw50T1Succinyl-CoA:acetate CoA-transferase/0.446
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.445
1h61PDNPentaerythritol tetranitrate reductase/0.445
1icpFMN12-oxophytodienoate reductase 11.3.1.420.445
1nvtNAPShikimate dehydrogenase (NADP(+))/0.445
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.445
1y9dTPPPyruvate oxidase1.2.3.30.445
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.445
2bf4FADNADPH--cytochrome P450 reductase/0.445
2ignFADPyranose 2-oxidase/0.445
2ikuLIYRenin3.4.23.150.445
2p6dSAHDiphthine synthase/0.445
2pb6SAHDiphthine synthase/0.445
2vetUMPThymidylate synthase/0.445
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.445
3c1y2BADNA integrity scanning protein DisA/0.445
3enkUPGUDP-glucose 4-epimerase/0.445
3gfbNADL-threonine 3-dehydrogenase/0.445
3gkaFMNN-ethylmaleimide reductase/0.445
3hgoFMN12-oxophytodienoate reductase 31.3.1.420.445
3il1B5DGlutamate receptor 2/0.445
3jusBCDLanosterol 14-alpha demethylase1.14.13.700.445
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.445
3px3T3QdTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase2.1.1.2350.445
3qlrNDPDihydrofolate reductase1.5.1.30.445
4ambDUDPutative glycosyl transferase/0.445
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.445
4xsvCTPEthanolamine-phosphate cytidylyltransferase2.7.7.140.445
4ycpFMNtRNA-dihydrouridine(16) synthase/0.445
1c9k5GPBifunctional adenosylcobalamin biosynthesis protein CobU/0.444
1q45FMN12-oxophytodienoate reductase 31.3.1.420.444
1ri1GTGmRNA cap guanine-N7 methyltransferase2.1.1.560.444
1sa4JANProtein farnesyltransferase subunit beta2.5.1.580.444
1tllFMNNitric oxide synthase, brain1.14.13.390.444
1ywgNADGlyceraldehyde-3-phosphate dehydrogenase/0.444
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.444
2eleSAHDiphthine synthase/0.444
2irzI02Beta-secretase 13.4.23.460.444
2vbdV10Isopenicillin N synthase1.21.3.10.444
2xfsJ01Uncharacterized protein/0.444
3d84NDPDihydrofolate reductase1.5.1.30.444
3djjFADGlutathione reductase, mitochondrial1.8.1.70.444
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.444
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.444
3ivgFG5Pantothenate synthetase6.3.2.10.444
3n4kSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.444
3phjDHKShikimate dehydrogenase (NADP(+))/0.444
3uoyFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.444
3vucHHERenin3.4.23.150.444
4arbC57Acetylcholinesterase3.1.1.70.444
4dptAGSMevalonate diphosphate decarboxylase/0.444
4isuIKMGlutamate receptor 2/0.444
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.443
1i9c5ADGlutamate mutase epsilon subunit/0.443
1ivsVAAValine--tRNA ligase6.1.1.90.443
1k7fIAVTryptophan synthase alpha chain/0.443
1n2hPAJPantothenate synthetase6.3.2.10.443
1o0sNAINAD-dependent malic enzyme, mitochondrial1.1.1.380.443
1s20NAD2,3-diketo-L-gulonate reductase1.1.1.1300.443
1toiHCIAspartate aminotransferase2.6.1.10.443
1tqf32PBeta-secretase 13.4.23.460.443
1u1gBBBUridine phosphorylase2.4.2.30.443
1x1cSAHC-20 methyltransferase/0.443
2ifaFMNUncharacterized protein/0.443
2oc4IMHPurine nucleoside phosphorylase2.4.2.10.443
2xq0BESLeukotriene A-4 hydrolase homolog3.3.2.60.443
2y99NADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase1.3.1.560.443
3clrFADElectron transfer flavoprotein subunit alpha/0.443
3intFDAUDP-galactopyranose mutase5.4.99.90.443
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.443
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.443
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.443
3oc4FADOxidoreductase, pyridine nucleotide-disulfide family/0.443
3r7kFDAProbable acyl CoA dehydrogenase/0.443
3vswR31Renin3.4.23.150.443
4a5lFADThioredoxin reductase/0.443
4a6rTA8Probable aminotransferase/0.443
4a99FADTetX family tetracycline inactivation enzyme/0.443
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.443
4fsl0VBBeta-secretase 13.4.23.460.443
4xr9NADCalS8/0.443
1dirNADDihydropteridine reductase1.5.1.340.442
1gpdNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.442
1hkuNADC-terminal-binding protein 11.1.10.442
1ld8U49Protein farnesyltransferase subunit beta2.5.1.580.442
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.442
2b8l5HABeta-secretase 13.4.23.460.442
2cndFADNitrate reductase [NADH]1.7.1.10.442
2dv3SAHDiphthine synthase/0.442
2dxxSAHDiphthine synthase/0.442
2ft9CHDFatty acid-binding protein 2, liver/0.442
2iqgF2IBeta-secretase 13.4.23.460.442
2j07HDFDeoxyribodipyrimidine photo-lyase4.1.99.30.442
2owuSAHDiphthine synthase/0.442
2p5fSAHDiphthine synthase/0.442
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.442
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.442
2xfyACXBeta-amylase3.2.1.20.442
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3sj7NDP3-oxoacyl-(Acyl-carrier-protein) reductase, putative/0.442
3zeiAWHO-acetylserine sulfhydrylase/0.442
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.442
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.442
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.442
4yvz3ATDNA integrity scanning protein DisA/0.442
5a0yCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.442
5a0yCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.442
5cfpC2EStimulator of interferon genes protein/0.442
1a59COA2-methylcitrate synthase/0.441
1e3sNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.441
1ia1NDPDihydrofolate reductase1.5.1.30.441
2emuSAHDiphthine synthase/0.441
2f99AKVAklanonic acid methyl ester cyclase AcmA5.5.1.230.441
2p5cSAHDiphthine synthase/0.441
2q7vFADThioredoxin reductase/0.441
2wf3ZY3Beta-secretase 13.4.23.460.441
2wf4ZY4Beta-secretase 13.4.23.460.441
3bgxMEFThymidylate synthase/0.441
3c212BADNA integrity scanning protein DisA/0.441
3clsFADElectron transfer flavoprotein subunit alpha/0.441
3lpkZ76Beta-secretase 13.4.23.460.441
3ojwFMNNADPH--cytochrome P450 reductase/0.441
3pndFADFAD:protein FMN transferase/0.441
3vydVYDRenin3.4.23.150.441
4b1rITCTetracycline repressor protein class D/0.441
4b4vL34Bifunctional protein FolD/0.441
4c13UMLUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase/0.441
4m4922YL-lactate dehydrogenase A chain1.1.1.270.441
4rnuFMNNADPH dehydrogenase 11.6.99.10.441
1b2lNDCAlcohol dehydrogenase1.1.1.10.440
1e79ATPATP synthase subunit alpha, mitochondrial/0.440
1e79ATPATP synthase subunit beta, mitochondrial3.6.3.140.440
1gcoNADGlucose 1-dehydrogenase1.1.1.470.440
1me6IVSPlasmepsin-23.4.23.390.440
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.440
1obbNADAlpha-glucosidase3.2.1.200.440
1u71MXADihydrofolate reductase1.5.1.30.440
2cv2GSUGlutamate--tRNA ligase6.1.1.170.440
2eh4SAHDiphthine synthase/0.440
2gcgNDPGlyoxylate reductase/hydroxypyruvate reductase1.1.1.790.440
2owvSAHDiphthine synthase/0.440
2xy3DUPSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.440
3d3xARG_ILE_MET_GLU_NH2Type E botulinum toxin/0.440
3ik6HCZGlutamate receptor 2/0.440
3mauEXTPutative sphingosine-1-phosphate lyase/0.440
3mknDNBPyrimidine-specific ribonucleoside hydrolase RihB/0.440
3p5pA3CTaxadiene synthase4.2.3.170.440
3t7sSAMUncharacterized protein/0.440
4de2DN3Beta-lactamase/0.440
4driRAPSerine/threonine-protein kinase mTOR2.7.11.10.440
4driRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.440
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
4nakPBQ2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic2.7.7.600.440
4nbwNADShort-chain dehydrogenase/reductase SDR/0.440
4q72FADBifunctional protein PutA/0.440
4qxp1YEStimulator of interferon genes protein/0.440
4rrrA3TThreonine--tRNA ligase6.1.1.30.440
4rv9SAHD-mycarose 3-C-methyltransferase/0.440
4s1iPLPPyridoxal kinase, putative/0.440
4twrNADNAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase/0.440
5ao1DG3Deoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.440
5czySAMEukaryotic huntingtin interacting protein B/0.440
7mhtSAHModification methylase HhaI2.1.1.370.440