scPDB - Distribution of Binding site Similarity values of 3nwb entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3nwb	659	Catechol O-methyltransferase	2.1.1.6

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
3nwb	659	Catechol O-methyltransferase	2.1.1.6	1.000
3nwe	662	Catechol O-methyltransferase	2.1.1.6	0.619
1jr4	CL4	Catechol O-methyltransferase	2.1.1.6	0.601
3a7d	FBN	Catechol O-methyltransferase	2.1.1.6	0.580
3hvk	719	Catechol O-methyltransferase	2.1.1.6	0.578
3nw9	637	Catechol O-methyltransferase	2.1.1.6	0.573
3ozs	OZS	Catechol O-methyltransferase	2.1.1.6	0.563
3hvi	619	Catechol O-methyltransferase	2.1.1.6	0.553
3ozt	OZZ	Catechol O-methyltransferase	2.1.1.6	0.541
3r6t	LU1	Catechol O-methyltransferase	2.1.1.6	0.525
3oe4	610	Catechol O-methyltransferase	2.1.1.6	0.508
3bgi	SAH	Thiopurine S-methyltransferase	2.1.1.67	0.479
3ozr	OZR	Catechol O-methyltransferase	2.1.1.6	0.475
1xon	PIL	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.471
3d4b	DZD	NAD-dependent protein deacetylase	/	0.471
5bp9	SAH	Putative methyltransferase protein	/	0.469
3lga	SAH	tRNA (adenine(57)-N(1)/adenine(58)-N(1))-methyltransferase TrmI	2.1.1.219	0.467
1rd4	L08	Integrin alpha-L	/	0.459
2zth	SAM	Catechol O-methyltransferase	2.1.1.6	0.459
3g4g	D71	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.456
4i9z	5BA	cGMP-specific 3',5'-cyclic phosphodiesterase	/	0.456
2qcu	FAD	Aerobic glycerol-3-phosphate dehydrogenase	1.1.5.3	0.454
3k4s	0MO	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.452
3vqr	FAD	Putative oxidoreductase	/	0.452
5e8j	SAH	mRNA cap guanine-N7 methyltransferase	2.1.1.56	0.451
1nqu	RDL	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.450
4phl	PIL	Phosphodiesterase	/	0.449
1kyx	CRM	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.448
1xom	CIO	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.448
2jj2	ANP	ATP synthase subunit beta, mitochondrial	3.6.3.14	0.448
3g58	988	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.448
4rv9	SAH	D-mycarose 3-C-methyltransferase	/	0.448
1sus	SAH	Caffeoyl-CoA O-methyltransferase	2.1.1.104	0.446
3c1t	MYC	Dihydroflavonol 4-reductase	1.1.1.219	0.446
3h4v	DVP	Pteridine reductase 1	1.5.1.33	0.446
3oe5	611	Catechol O-methyltransferase	2.1.1.6	0.446
4gh6	LUO	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.446
1mcz	RMN	Benzoylformate decarboxylase	4.1.1.7	0.444
2ytz	SAH	tRNA (guanine(26)-N(2))-dimethyltransferase	/	0.444
3bgv	SAH	mRNA cap guanine-N7 methyltransferase	2.1.1.56	0.444
1p6j	H4B	Nitric oxide synthase, brain	1.14.13.39	0.443
3a1l	2CC	Cytochrome P450	/	0.443
3g4i	D71	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.443
1oyn	ROL	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.442
1udt	VIA	cGMP-specific 3',5'-cyclic phosphodiesterase	/	0.442
1so2	666	cGMP-inhibited 3',5'-cyclic phosphodiesterase B	3.1.4.17	0.441
2g1p	SAH	DNA adenine methylase	2.1.1.72	0.441
3a25	SAM	tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase	/	0.441
5c1m	CLR	Mu-type opioid receptor	/	0.441
3dyn	PCG	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.440
3p9k	SAH	Caffeic acid O-methyltransferase	/	0.440