scPDB - Distribution of Binding site Similarity values of 3ntz entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3ntz	3TZ	Dihydrofolate reductase	1.5.1.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
3ntz	3TZ	Dihydrofolate reductase	1.5.1.3	1.000
3ghw	GHW	Dihydrofolate reductase	1.5.1.3	0.601
4keb	FOL	Dihydrofolate reductase	1.5.1.3	0.601
3gi2	GHW	Dihydrofolate reductase	1.5.1.3	0.599
1u72	MTX	Dihydrofolate reductase	1.5.1.3	0.595
2w3m	FOL	Dihydrofolate reductase	1.5.1.3	0.593
1hfr	MOT	Dihydrofolate reductase	1.5.1.3	0.576
4m6l	21V	Dihydrofolate reductase	1.5.1.3	0.571
4m6k	FOL	Dihydrofolate reductase	1.5.1.3	0.567
1hfq	MOT	Dihydrofolate reductase	1.5.1.3	0.565
3nu0	3TU	Dihydrofolate reductase	1.5.1.3	0.548
1kms	LIH	Dihydrofolate reductase	1.5.1.3	0.538
2dhf	DZF	Dihydrofolate reductase	1.5.1.3	0.531
3d80	Q22	Dihydrofolate reductase	1.5.1.3	0.526
3gyf	51P	Dihydrofolate reductase	1.5.1.3	0.525
1ohj	COP	Dihydrofolate reductase	1.5.1.3	0.523
1drf	FOL	Dihydrofolate reductase	1.5.1.3	0.521
3ghv	GHC	Dihydrofolate reductase	1.5.1.3	0.521
1kmv	LII	Dihydrofolate reductase	1.5.1.3	0.513
1ohk	COP	Dihydrofolate reductase	1.5.1.3	0.510
3l3r	OAG	Dihydrofolate reductase	1.5.1.3	0.509
1hfp	MOT	Dihydrofolate reductase	1.5.1.3	0.502
3nxr	D2D	Dihydrofolate reductase	1.5.1.3	0.495
4kfj	FOL	Dihydrofolate reductase	1.5.1.3	0.495
1dhf	FOL	Dihydrofolate reductase	1.5.1.3	0.492
1s3u	TQD	Dihydrofolate reductase	1.5.1.3	0.487
3nrr	D16	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.486
1mvt	DTM	Dihydrofolate reductase	1.5.1.3	0.484
3nxt	D2E	Dihydrofolate reductase	1.5.1.3	0.483
3n0h	TOP	Dihydrofolate reductase	1.5.1.3	0.481
3nxy	D2H	Dihydrofolate reductase	1.5.1.3	0.481
1pd9	CO4	Dihydrofolate reductase	1.5.1.3	0.479
2w3a	TOP	Dihydrofolate reductase	1.5.1.3	0.479
2fzj	DH3	Dihydrofolate reductase	1.5.1.3	0.476
4dpd	DHF	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.476
4ky4	04J	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.476
1mvs	DTM	Dihydrofolate reductase	1.5.1.3	0.469
4eil	FOL	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.468
1u70	MTX	Dihydrofolate reductase	1.5.1.3	0.467
3k45	51P	Dihydrofolate reductase	1.5.1.3	0.467
1dls	MTX	Dihydrofolate reductase	1.5.1.3	0.464
4kfj	1R0	Dihydrofolate reductase	1.5.1.3	0.463
3s7a	684	Dihydrofolate reductase	1.5.1.3	0.460
1blz	ACV	Isopenicillin N synthase	1.21.3.1	0.458
2vbp	VB1	Isopenicillin N synthase	1.21.3.1	0.454
1pd8	CO4	Dihydrofolate reductase	1.5.1.3	0.453
1hb3	SCV	Isopenicillin N synthase	1.21.3.1	0.452
4h6p	FMN	Chromate reductase	/	0.450
2y6f	M9F	Isopenicillin N synthase	1.21.3.1	0.449
1mkd	ZAR	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.447
1qiq	ACC	Isopenicillin N synthase	1.21.3.1	0.445
3hxe	BD8	Geranylgeranyl transferase type-2 subunit beta	2.5.1.60	0.445
2ouu	35G	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.443
4iar	ERM	5-hydroxytryptamine receptor 1B	/	0.440