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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3ntrNADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.18

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3ntrNADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.181.000
3ntqNADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.694
3nt5NAIInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.515
3ec7NADInositol 2-dehydrogenase/0.475
4l8vNAPInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.470
3nt2NADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.466
3nt4NAIInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.452
3g70A5TRenin3.4.23.150.450
4fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.448
4fapARDSerine/threonine-protein kinase mTOR2.7.11.10.448
1lc3NADBiliverdin reductase A1.3.1.240.447
2fapRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.447
2fapRADSerine/threonine-protein kinase mTOR2.7.11.10.447
1eq2ADQADP-L-glycero-D-manno-heptose-6-epimerase/0.446
1fapRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.442
1fapRAPSerine/threonine-protein kinase mTOR2.7.11.10.442
2gesCOKPantothenate kinase2.7.1.330.440
4haiI23Bifunctional epoxide hydrolase 23.1.3.760.440