scPDB - Distribution of Binding site Similarity values of 3nrr entry / Site 3

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3nrr	D16	Bifunctional dihydrofolate reductase-thymidylate synthase

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
3nrr	D16	Bifunctional dihydrofolate reductase-thymidylate synthase	/	1.000
2w3m	FOL	Dihydrofolate reductase	1.5.1.3	0.490
4m6l	21V	Dihydrofolate reductase	1.5.1.3	0.487
2fzj	DH3	Dihydrofolate reductase	1.5.1.3	0.484
3l3r	OAG	Dihydrofolate reductase	1.5.1.3	0.483
1kms	LIH	Dihydrofolate reductase	1.5.1.3	0.477
1hfq	MOT	Dihydrofolate reductase	1.5.1.3	0.475
4keb	FOL	Dihydrofolate reductase	1.5.1.3	0.464
4eil	FOL	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.460
1ohk	COP	Dihydrofolate reductase	1.5.1.3	0.458
4m6k	FOL	Dihydrofolate reductase	1.5.1.3	0.457
1pkf	EPD	Epothilone C/D epoxidase	1.14	0.455
1u72	MTX	Dihydrofolate reductase	1.5.1.3	0.455
4ky4	04J	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.455
1hfr	MOT	Dihydrofolate reductase	1.5.1.3	0.452
3qm4	PN0	Cytochrome P450 2D6	/	0.448
1q5d	EPB	Epothilone C/D epoxidase	1.14	0.445
3ghw	GHW	Dihydrofolate reductase	1.5.1.3	0.443
3ntz	3TZ	Dihydrofolate reductase	1.5.1.3	0.443
2dhf	DZF	Dihydrofolate reductase	1.5.1.3	0.441
1ohj	COP	Dihydrofolate reductase	1.5.1.3	0.440