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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3ne6DCPDNA-directed DNA polymerase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3ne6DCPDNA-directed DNA polymerase/1.000
4dtjTTPDNA-directed DNA polymerase/0.682
3supDCPDNA-directed DNA polymerase/0.674
4fjlDGTDNA-directed DNA polymerase/0.668
4dtmDCPDNA-directed DNA polymerase/0.655
4fjjTTPDNA-directed DNA polymerase/0.647
4dtpDGTDNA-directed DNA polymerase/0.638
4fj5DTPDNA-directed DNA polymerase/0.616
3lzjCTPDNA-directed DNA polymerase/0.605
4dtxTTPDNA-directed DNA polymerase/0.590
4fk4DGTDNA-directed DNA polymerase/0.583
4m3tATPDNA-directed DNA polymerase/0.581
4m3xATPDNA-directed DNA polymerase/0.577
4fjmDCPDNA-directed DNA polymerase/0.569
4m42ATPDNA-directed DNA polymerase/0.564
4khyTTPDNA-directed DNA polymerase/0.535
4dtoDCPDNA-directed DNA polymerase/0.528
4ptfDCPDNA polymerase epsilon catalytic subunit A2.7.7.70.483