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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3nbzGTPGTP-binding nuclear protein Ran

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3nbzGTPGTP-binding nuclear protein Ran/1.000
2x19GTPGTP-binding nuclear protein GSP1/CNR1/0.557
4ol0GTPGTP-binding nuclear protein Ran/0.507
4k81GTPGTPase HRas/0.505
3w3zGTPGTP-binding nuclear protein Ran/0.474
5dhaGNPGTP-binding nuclear protein Ran/0.454
2gilGTPRas-related protein Rab-6A/0.451
4xoiGTPTransforming protein RhoA/0.447
3e5hGNPRas-related protein Rab-28/0.444
3wygGTPGTP-binding nuclear protein GSP1/CNR1/0.440