sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3mzh | CMP | CRP-like cAMP-activated global transcriptional regulator |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3mzh | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 1.000 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.560 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.542 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.519 | |
| 4i0b | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.508 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.494 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.493 | |
| 3i59 | N6S | CRP-like cAMP-activated global transcriptional regulator | / | 0.492 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.490 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.488 | |
| 4i09 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.488 | |
| 3ryp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.486 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.485 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.485 | |
| 4y8v | ADP | Acyl-CoA synthetase (NDP forming) | / | 0.483 | |
| 1g6n | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.482 | |
| 1gqt | ACP | Ribokinase | / | 0.481 | |
| 1i6x | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.480 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.480 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.480 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.479 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.474 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.474 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.474 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.472 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.472 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.471 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.471 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.471 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.471 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.468 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.468 | |
| 2cmv | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.468 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.468 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.468 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.468 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 2xpw | OTC | Tetracycline repressor protein class D | / | 0.467 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.467 | |
| 4n9i | PCG | Catabolite expression activator | / | 0.467 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.467 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 1i7l | ATP | Synapsin-2 | / | 0.465 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.465 | |
| 2gzw | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.465 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.464 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.464 | |
| 3ryr | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.464 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.464 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.464 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.462 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.462 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.462 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.462 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.462 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.462 | |
| 5l3r | GCP | Cell division protein FtsY homolog, chloroplastic | / | 0.462 | |
| 2xpv | MIY | Tetracycline repressor protein class D | / | 0.461 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.461 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.461 | |
| 1nai | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.460 | |
| 1w87 | NAP | Ferredoxin--NADP reductase | 1.18.1.2 | 0.460 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.460 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.460 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.459 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.459 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.459 | |
| 3zc3 | NAP | Ferredoxin--NADP reductase | 1.18.1.2 | 0.459 | |
| 4abz | T1C | Tetracycline repressor protein class D | / | 0.459 | |
| 4aux | XTC | Tetracycline repressor protein class D | / | 0.459 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.459 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.458 | |
| 1t0l | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.458 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.458 | |
| 2oor | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.458 | |
| 3he3 | FAD | UDP-galactopyranose mutase | / | 0.458 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.458 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.458 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.457 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.457 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.457 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.456 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.456 | |
| 1yqx | NAP | Sinapyl alcohol dehydrogenase | / | 0.456 | |
| 2daa | DCS | D-alanine aminotransferase | 2.6.1.21 | 0.456 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.456 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.455 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1yqd | NAP | Sinapyl alcohol dehydrogenase | / | 0.455 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.455 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.455 | |
| 5ios | FAD | Flavin-dependent thymidylate synthase | 2.1.1.148 | 0.455 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.454 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.454 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.454 | |
| 3cis | ATP | Universal stress protein Rv2623 | / | 0.454 | |
| 3ovb | ATP | CCA-adding enzyme | 2.7.7.72 | 0.454 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.453 | |
| 2avi | BTN | Avidin | / | 0.453 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.453 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.453 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.453 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.453 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.453 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.453 | |
| 3w23 | 3RO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.453 | |
| 4hbn | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.453 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.453 | |
| 5j23 | A2R | Putative 2-hydroxyacid dehydrogenase | / | 0.453 | |
| 1ng4 | FAD | Glycine oxidase | 1.4.3.19 | 0.452 | |
| 1rj9 | GCP | Signal recognition particle receptor FtsY | / | 0.452 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.452 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.452 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.452 | |
| 2xw7 | NDP | Dihydrofolate reductase | / | 0.452 | |
| 3baz | NAP | Hydroxyphenylpyruvate reductase | 1.1.1.237 | 0.452 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.452 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3uko | NAD | Alcohol dehydrogenase class-3 | / | 0.452 | |
| 3uqd | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.452 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.452 | |
| 4e2d | FMN | Dehydrogenase | / | 0.452 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.452 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.451 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.451 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.451 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.451 | |
| 4xyb | NDP | Formate dehydrogenase | / | 0.451 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.450 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.450 | |
| 1zdw | FLV | Prenyltransferase | / | 0.450 | |
| 2cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.450 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.450 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.450 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.450 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 4d5g | FAD | Cyclohexane-1,2-dione hydrolase | 3.7.1.11 | 0.450 | |
| 4die | C5P | Cytidylate kinase | / | 0.450 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.450 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.450 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.450 | |
| 1okk | GCP | Signal recognition particle protein | / | 0.449 | |
| 1okk | GCP | Signal recognition particle receptor FtsY | / | 0.449 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.449 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.449 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.449 | |
| 3ac3 | KSH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.449 | |
| 3d8b | ADP | Fidgetin-like protein 1 | 3.6.4 | 0.449 | |
| 3iid | APR | Core histone macro-H2A.1 | / | 0.449 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.449 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.449 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4kxn | 6K6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.449 | |
| 5a3b | APR | SIR2 family protein | / | 0.449 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 1hw5 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.448 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.448 | |
| 1llu | NAD | Alcohol dehydrogenase | / | 0.448 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.448 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.448 | |
| 2itu | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.448 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.448 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.447 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.447 | |
| 1q12 | ATP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.447 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.447 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.447 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3n0c | FAD | Flavin-dependent thymidylate synthase | 2.1.1.148 | 0.447 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.447 | |
| 4j31 | FAD | Kynurenine 3-monooxygenase | / | 0.447 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.447 | |
| 5c88 | COA | N-alpha-acetyltransferase | / | 0.447 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.446 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.446 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.446 | |
| 3hv5 | R24 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.446 | |
| 3tqc | ADP | Pantothenate kinase | / | 0.446 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.446 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.446 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.446 | |
| 4xw4 | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 5iqe | GNP | Bifunctional AAC/APH | 2.3.1 | 0.446 | |
| 1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.445 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.445 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.445 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.445 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1m17 | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.445 | |
| 1t7i | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.445 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.445 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.445 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.445 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.445 | |
| 2o7o | DXT | Tetracycline repressor protein class D | / | 0.445 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.445 | |
| 2xgs | 44P | Uncharacterized protein | / | 0.445 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.445 | |
| 3hmm | 855 | TGF-beta receptor type-1 | 2.7.11.30 | 0.445 | |
| 3kgc | LY7 | Glutamate receptor 2 | / | 0.445 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.445 | |
| 4j36 | FAD | Kynurenine 3-monooxygenase | / | 0.445 | |
| 4l4x | NDP | AmphI | / | 0.445 | |
| 4pyt | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.445 | |
| 1ghe | ACO | Acetyltransferase | 2.3.1 | 0.444 | |
| 1iy8 | NAD | Levodione reductase | / | 0.444 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.444 | |
| 2ntr | L00 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2pan | FAD | Glyoxylate carboligase | 4.1.1.47 | 0.444 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.444 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.444 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.444 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.444 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.444 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.444 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.443 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1kqn | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.443 | |
| 1lqu | NDP | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.443 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 1ybm | NAP | Uncharacterized protein At5g02240 | / | 0.443 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2qu6 | 857 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.443 | |
| 2y4g | TIR | TamL | / | 0.443 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.443 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.443 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.443 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.443 | |
| 4kwh | NAP | Reductase homolog | / | 0.443 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.442 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.442 | |
| 2is0 | I03 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.442 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.442 | |
| 3fpa | DTB | ATP-dependent dethiobiotin synthetase BioD | / | 0.442 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.442 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.442 | |
| 3r2f | PB0 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.442 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.442 | |
| 4k9h | 1QU | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4nxx | GDP | Mitochondrial dynamics protein MID51 | / | 0.442 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.442 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.442 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.441 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.441 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.441 | |
| 1o8c | NDP | Probable acrylyl-CoA reductase AcuI | 1.3.1.84 | 0.441 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.441 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.441 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.441 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.441 | |
| 3cgc | COA | Coenzyme A disulfide reductase | / | 0.441 | |
| 3cop | ADP | Glycogen synthase | 2.4.1.21 | 0.441 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.441 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.441 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.441 | |
| 3tz3 | B36 | Acetyl-CoA carboxylase | / | 0.441 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.441 | |
| 4dpi | 0N1 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4eo3 | FMN | Bacterioferritin comigratory protein/NADH dehydrogenase | / | 0.441 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.441 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.441 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.441 | |
| 5dp2 | NAP | CurF | / | 0.441 | |
| 1jq5 | NAD | Glycerol dehydrogenase | 1.1.1.6 | 0.440 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 1m6i | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.440 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 1svg | I04 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.440 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 2g5c | NAD | Prephenate dehydrogenase | / | 0.440 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.440 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.440 | |
| 2q5q | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.440 | |
| 2uyw | BTN | Avd protein | / | 0.440 | |
| 2wez | ZYE | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.440 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.440 | |
| 3fcj | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.440 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.440 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.440 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.440 | |
| 4jdr | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.440 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 |