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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3mzcS6ICarbonic anhydrase 24.2.1.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3mzcS6ICarbonic anhydrase 24.2.1.11.000
3oysOYSCarbonic anhydrase 24.2.1.10.925
4itoMPXCarbonic anhydrase 24.2.1.10.890
4ilx1EZCarbonic anhydrase 24.2.1.10.868
3mnaDWHCarbonic anhydrase 24.2.1.10.865
3n0nP9BCarbonic anhydrase 24.2.1.10.847
3n4bWWZCarbonic anhydrase 24.2.1.10.842
4bf6X0QCarbonic anhydrase 24.2.1.10.806
3betCTFCarbonic anhydrase 24.2.1.10.805
3qykIE2Carbonic anhydrase 24.2.1.10.805
3oimVZ5Carbonic anhydrase 24.2.1.10.799
4itp1GDCarbonic anhydrase 24.2.1.10.799
3mmfD9HCarbonic anhydrase 24.2.1.10.797
3n3jWWVCarbonic anhydrase 24.2.1.10.792
3ml2SU0Carbonic anhydrase 24.2.1.10.787
2wejFB2Carbonic anhydrase 24.2.1.10.784
3sbhE65Carbonic anhydrase 24.2.1.10.767
1if4FBSCarbonic anhydrase 24.2.1.10.744
1kwrSG2Carbonic anhydrase 24.2.1.10.736
3m2nJ74Carbonic anhydrase 24.2.1.10.736
4iwz1GOCarbonic anhydrase 24.2.1.10.736
3mhoJ43Carbonic anhydrase 24.2.1.10.734
1bn1AL5Carbonic anhydrase 24.2.1.10.728
2h15B19Carbonic anhydrase 24.2.1.10.726
3oyqOYQCarbonic anhydrase 24.2.1.10.723
3eft3BSCarbonic anhydrase 24.2.1.10.722
1bntAL2Carbonic anhydrase 24.2.1.10.720
1bn4AL9Carbonic anhydrase 24.2.1.10.710
1bnnAL1Carbonic anhydrase 24.2.1.10.709
2wehFB1Carbonic anhydrase 24.2.1.10.709
3kigDA4Carbonic anhydrase 24.2.1.10.703
3dazMZMCarbonic anhydrase 24.2.1.10.702
1g52F2BCarbonic anhydrase 24.2.1.10.701
3d9zD9ZCarbonic anhydrase 24.2.1.10.701
1g1dFSBCarbonic anhydrase 24.2.1.10.700
3l14I7BCarbonic anhydrase 24.2.1.10.699
1cnyEG3Carbonic anhydrase 24.2.1.10.697
1i90INMCarbonic anhydrase 24.2.1.10.695
4m2rBZ1Carbonic anhydrase 24.2.1.10.695
1oq5CELCarbonic anhydrase 24.2.1.10.694
3sbiE90Carbonic anhydrase 24.2.1.10.694
3k2fNKXCarbonic anhydrase 24.2.1.10.691
4dz7D02Carbonic anhydrase 24.2.1.10.687
1a42BZUCarbonic anhydrase 24.2.1.10.686
1if6FBUCarbonic anhydrase 24.2.1.10.685
3m98E02Carbonic anhydrase 24.2.1.10.685
3ni5C1HCarbonic anhydrase 24.2.1.10.685
3t84SG6Carbonic anhydrase 24.2.1.10.683
4kap1QVCarbonic anhydrase 24.2.1.10.683
4bf19FKCarbonic anhydrase 24.2.1.10.682
2wegFBVCarbonic anhydrase 24.2.1.10.681
3s8xE59Carbonic anhydrase 24.2.1.10.679
3d8wD8WCarbonic anhydrase 24.2.1.10.678
3oy0OY0Carbonic anhydrase 24.2.1.10.678
3m2yBE0Carbonic anhydrase 24.2.1.10.677
3ffpLC1Carbonic anhydrase 24.2.1.10.674
5fltVJJCarbonic anhydrase 24.2.1.10.674
2eu3FF3Carbonic anhydrase 24.2.1.10.673
3f4xKLTCarbonic anhydrase 24.2.1.10.673
4kniE1ECarbonic anhydrase 24.2.1.10.673
4knjE1FCarbonic anhydrase 24.2.1.10.671
1i91INQCarbonic anhydrase 24.2.1.10.669
4m2vBZ1Carbonic anhydrase 24.2.1.10.669
1bnwTPDCarbonic anhydrase 24.2.1.10.668
3dd82C7Carbonic anhydrase 24.2.1.10.666
3oikWZBCarbonic anhydrase 24.2.1.10.662
2powI7CCarbonic anhydrase 24.2.1.10.661
3mhlJ71Carbonic anhydrase 24.2.1.10.661
4mo82VQCarbonic anhydrase 24.2.1.10.661
2weoFBWCarbonic anhydrase 24.2.1.10.660
3dc3AZMCarbonic anhydrase 24.2.1.10.660
4k13ETSCarbonic anhydrase 24.2.1.10.660
3n2pAYXCarbonic anhydrase 24.2.1.10.657
1okmSABCarbonic anhydrase 24.2.1.10.654
3dccD9ZCarbonic anhydrase 24.2.1.10.654
4n16CHDCarbonic anhydrase 24.2.1.10.654
3dcsMZMCarbonic anhydrase 24.2.1.10.653
3t82SG4Carbonic anhydrase 24.2.1.10.653
1cilETSCarbonic anhydrase 24.2.1.10.649
3dcwEZLCarbonic anhydrase 24.2.1.10.649
1zsbAZMCarbonic anhydrase 24.2.1.10.648
3b4fTUOCarbonic anhydrase 24.2.1.10.646
3saxE50Carbonic anhydrase 24.2.1.10.645
1bnmAL8Carbonic anhydrase 24.2.1.10.643
1g4jFFBCarbonic anhydrase 24.2.1.10.643
3m5eJDRCarbonic anhydrase 24.2.1.10.642
1cnxEG2Carbonic anhydrase 24.2.1.10.636
1i9nIOACarbonic anhydrase 24.2.1.10.636
3s9tE49Carbonic anhydrase 24.2.1.10.635
4pxxCHDCarbonic anhydrase 24.2.1.10.635
1ttm667Carbonic anhydrase 24.2.1.10.634
3po6DT9Carbonic anhydrase 24.2.1.10.634
1i8zINLCarbonic anhydrase 24.2.1.10.626
2q1qOSPCarbonic anhydrase 24.2.1.10.626
3mhiJ90Carbonic anhydrase 24.2.1.10.626
1oklMNSCarbonic anhydrase 24.2.1.10.624
3myqE27Carbonic anhydrase 24.2.1.10.624
3p5lIT5Carbonic anhydrase 24.2.1.10.624
3nb5R21Carbonic anhydrase 24.2.1.10.623
3mdzEZLCarbonic anhydrase 74.2.1.10.622
3hkuTORCarbonic anhydrase 24.2.1.10.621
3mhcARZCarbonic anhydrase 24.2.1.10.621
1eouSMSCarbonic anhydrase 24.2.1.10.620
1if7SBRCarbonic anhydrase 24.2.1.10.619
3igpDT7Carbonic anhydrase 24.2.1.10.613
4k0tD9ZCarbonic anhydrase 24.2.1.10.613
1oknSTBCarbonic anhydrase 24.2.1.10.611
3dd0EZLCarbonic anhydrase 24.2.1.10.611
4kp8E1GCarbonic anhydrase 124.2.1.10.610
1xpz4TZCarbonic anhydrase 24.2.1.10.603
3m96E38Carbonic anhydrase 24.2.1.10.603
3v2jAZMCarbonic anhydrase 24.2.1.10.600
1kwqSG1Carbonic anhydrase 24.2.1.10.598
1xq04TRCarbonic anhydrase 24.2.1.10.598
2x7uWZACarbonic anhydrase 24.2.1.10.597
1g4oBSBCarbonic anhydrase 24.2.1.10.595
1bnqAL4Carbonic anhydrase 24.2.1.10.594
1g54FFBCarbonic anhydrase 24.2.1.10.593
1g45FSBCarbonic anhydrase 24.2.1.10.592
4lu3AZMCarbonic anhydrase 144.2.1.10.592
3m67E36Carbonic anhydrase 24.2.1.10.590
3zncBZ1Carbonic anhydrase 44.2.1.10.588
1jd0AZMCarbonic anhydrase 124.2.1.10.582
3dbuD8WCarbonic anhydrase 24.2.1.10.582
1cnwEG1Carbonic anhydrase 24.2.1.10.580
2wd2MS5Carbonic anhydrase 24.2.1.10.579
1if5FBTCarbonic anhydrase 24.2.1.10.577
2h4nAZMCarbonic anhydrase 24.2.1.10.577
3m40J45Carbonic anhydrase 24.2.1.10.575
4ht2V50Carbonic anhydrase 124.2.1.10.575
2x7tWZBCarbonic anhydrase 24.2.1.10.568
1i9qIOFCarbonic anhydrase 24.2.1.10.563
1bnuAL3Carbonic anhydrase 24.2.1.10.562
1rj6AZMCarbonic anhydrase 144.2.1.10.562
4k0zMZMCarbonic anhydrase 24.2.1.10.561
1bnvAL7Carbonic anhydrase 24.2.1.10.557
3rz8RZ8Carbonic anhydrase 24.2.1.10.555
4kp5E1FCarbonic anhydrase 124.2.1.10.554
4x5sAZMCarbonic anhydrase (Carbonate dehydratase)/0.554
3t85SG7Carbonic anhydrase 24.2.1.10.551
3bl1BL1Carbonic anhydrase 24.2.1.10.543
4uovAZMCarbonate dehydratase/0.543
3f7uAG4Carbonic anhydrase 44.2.1.10.541
4xiwAZMCarbonic anhydrase, alpha type/0.540
5fl49FKCarbonic anhydrase 94.2.1.10.535
1ydaAZMCarbonic anhydrase 24.2.1.10.534
4knmE1ECarbonic anhydrase 134.2.1.10.533
3f7bAG5Carbonic anhydrase 44.2.1.10.527
1i9pIOECarbonic anhydrase 24.2.1.10.526
3fw3ETSCarbonic anhydrase 44.2.1.10.526
1dmyAZMCarbonic anhydrase 5A, mitochondrial4.2.1.10.525
4kbyC2EStimulator of interferon genes protein/0.520
1if8SBSCarbonic anhydrase 24.2.1.10.517
1h50FMNPentaerythritol tetranitrate reductase/0.516
3p74FMNPentaerythritol tetranitrate reductase/0.513
3lxeTORCarbonic anhydrase 14.2.1.10.511
3p62FMNPentaerythritol tetranitrate reductase/0.511
1bn3AL6Carbonic anhydrase 24.2.1.10.504
1q45FMN12-oxophytodienoate reductase 31.3.1.420.504
4knnE1FCarbonic anhydrase 134.2.1.10.504
1h51FMNPentaerythritol tetranitrate reductase/0.502
4mihFADPyranose 2-oxidase1.1.3.100.498
1h63FMNPentaerythritol tetranitrate reductase/0.496
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.495
3f03FMNPentaerythritol tetranitrate reductase/0.494
4bfvZVVPantothenate kinase2.7.1.330.494
4iae1DXAlr2278 protein/0.494
3zbsOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.490
4iah1DXAlr2278 protein/0.490
2vteIK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.489
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.489
3h3t16HCollagen type IV alpha-3-binding protein/0.488
4bfzZVZPantothenate kinase2.7.1.330.488
1vyrFMNPentaerythritol tetranitrate reductase/0.487
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.486
3h3qH13Collagen type IV alpha-3-binding protein/0.486
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.486
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.485
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.482
4dbc3QPAspartate aminotransferase2.6.1.10.482
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.482
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.482
4ejvLCLTranscriptional regulator TcaR/0.482
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.481
2gv8NDPThiol-specific monooxygenase1.14.130.481
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.481
3p82FMNPentaerythritol tetranitrate reductase/0.481
4a81DXCMajor pollen allergen Bet v 1-A/0.481
3l6jZ90Alr2278 protein/0.480
1rc4DDFDihydrofolate reductase1.5.1.30.478
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.478
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.478
3vydVYDRenin3.4.23.150.478
4wdgA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.478
2rqfJH3Hemolymph juvenile hormone binding protein/0.475
5a0112VO-glycosyltransferase/0.475
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.474
3zs7ATPPyridoxine/pyridoxal/pyridoxamine kinase/0.474
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.474
3own3OXRenin3.4.23.150.473
1w6hTITPlasmepsin-23.4.23.390.472
2q3oFMN12-oxophytodienoate reductase 31.3.1.420.472
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.472
1b2lNDCAlcohol dehydrogenase1.1.1.10.471
1xe65FPPlasmepsin-23.4.23.390.471
7stdCRPScytalone dehydratase4.2.1.940.471
1fm4DXCMajor pollen allergen Bet v 1-L/0.470
4jqh1MFAlr2278 protein/0.470
1obnASVIsopenicillin N synthase1.21.3.10.469
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.469
2hs6FMN12-oxophytodienoate reductase 31.3.1.420.469
3apwDP0Alpha-1-acid glycoprotein 2/0.469
3hgoFMN12-oxophytodienoate reductase 31.3.1.420.469
3qvpFADGlucose oxidase1.1.3.40.469
4cdmFO1Deoxyribodipyrimidine photolyase/0.469
4eb5PLPCysteine desulfurase IscS 2/0.469
4jicFMNGTN Reductase/0.469
1bwsNDPGDP-L-fucose synthase/0.468
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.468
2xpc051UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.468
2zvcSAHPrecorrin-3 C17-methyltransferase/0.468
3qe2FMNNADPH--cytochrome P450 reductase/0.468
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.467
2g226IGRenin3.4.23.150.467
2yozOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.467
3qgf46FGenome polyprotein2.7.7.480.467
4a6rTA8Probable aminotransferase/0.467
4a862ANMajor pollen allergen Bet v 1-A/0.467
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.466
2g1o2IGRenin3.4.23.150.466
2qimZEAClass 10 plant pathogenesis-related protein/0.466
5c1d12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.466
1obbNADAlpha-glucosidase3.2.1.200.465
2ea2F77Methionine aminopeptidase 2/0.465
2vf3GVS4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.465
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.465
3eufBAUUridine phosphorylase 1/0.465
1icpFMN12-oxophytodienoate reductase 11.3.1.420.464
1rftPXMPyridoxal kinase2.7.1.350.464
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.464
1vbiNADMalate/L-lactate dehydrogenase family protein/0.464
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.464
4dptAGSMevalonate diphosphate decarboxylase/0.464
4rnuFMNNADPH dehydrogenase 11.6.99.10.464
1egdFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.463
1me6IVSPlasmepsin-23.4.23.390.463
1t7o152Carnitine O-acetyltransferase2.3.1.70.463
3fhxPXLPyridoxal kinase2.7.1.350.463
3h3sH15Collagen type IV alpha-3-binding protein/0.463
4a83DXCMajor pollen allergen Bet v 1-A/0.463
4b4vL34Bifunctional protein FolD/0.463
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.463
1gpdNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.462
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.462
1u1gBBBUridine phosphorylase2.4.2.30.462
2abbFMNPentaerythritol tetranitrate reductase/0.462
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.462
1b8vNADMalate dehydrogenase/0.461
1gky5GPGuanylate kinase2.7.4.80.461
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.461
2oapANPType II secretion system protein (GspE-2)/0.461
3e6eDCSAlanine racemase/0.461
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.461
3nl6TPSUncharacterized protein/0.461
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.461
1culFOKAdenylate cyclase type 2/0.460
1culFOKAdenylate cyclase type 5/0.460
1u1f183Uridine phosphorylase2.4.2.30.460
2a9y26AAdenosine kinase2.7.1.200.460
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.460
2g1n1IGRenin3.4.23.150.460
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.460
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.460
3p8iFMNPentaerythritol tetranitrate reductase/0.460
3qj0QI3Botulinum neurotoxin type A3.4.24.690.460
4lzwTHMUridine phosphorylase/0.460
1buxPPSNucleoside diphosphate kinase, cytosolic2.7.4.60.459
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.459
1s64778Geranylgeranyl transferase type-1 subunit beta2.5.1.590.459
3fr5I4AFatty acid-binding protein, adipocyte/0.459
4cf6CBDNAD(P)H dehydrogenase [quinone] 11.6.5.20.459
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.458
1kh3ANPArgininosuccinate synthase/0.458
2vbdV10Isopenicillin N synthase1.21.3.10.458
2vtdLKMUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.458
2w6cBM4Acetylcholinesterase3.1.1.70.458
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
3w6hAZMCarbonic anhydrase 14.2.1.10.458
4jsr1NQNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.458
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.458
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.457
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.457
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.457
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.457
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.457
2ea4F79Methionine aminopeptidase 2/0.457
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.457
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
1cf3FADGlucose oxidase1.1.3.40.456
1icqFMN12-oxophytodienoate reductase 11.3.1.420.456
1mjbACOHistone acetyltransferase ESA1/0.456
1qpf858Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.456
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.456
2hs8FMN12-oxophytodienoate reductase 31.3.1.420.456
2idkC2FGlycine N-methyltransferase2.1.1.200.456
2iko7IGRenin3.4.23.150.456
3gkaFMNN-ethylmaleimide reductase/0.456
3gwfNAPCyclohexanone monooxygenase/0.456
3h3r14HCollagen type IV alpha-3-binding protein/0.456
3p80P80Pentaerythritol tetranitrate reductase/0.456
4ey6GNTAcetylcholinesterase3.1.1.70.456
4q0kGA3Phytohormone-binding protein/0.456
4x7vMIVMycinamicin III 3''-O-methyltransferase2.1.1.2370.456
4x7wMVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.456
1b5eDCMDeoxycytidylate 5-hydroxymethyltransferase2.1.2.80.455
1hb1OCVIsopenicillin N synthase1.21.3.10.455
2d3aADPGlutamine synthetase root isozyme 36.3.1.20.455
2i7nACOPantothenate kinase 12.7.1.330.455
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.455
4du82P0Mevalonate diphosphate decarboxylase/0.455
4xr9NADCalS8/0.455
1bl4AP1Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.454
2d29FADAcyl-CoA dehydrogenase/0.454
3bk2U5PRibonuclease J/0.454
3qfrFMNNADPH--cytochrome P450 reductase/0.454
3v2uATPProtein GAL3/0.454
3zeiAWHO-acetylserine sulfhydrylase/0.454
4m83ERYOleandomycin glycosyltransferase2.4.10.454
4p9dTMPDeoxycytidylate deaminase/0.454
4relKMPGlycosyltransferase/0.454
5bnw12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.454
1bk0ACVIsopenicillin N synthase1.21.3.10.453
1kw9BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.453
1qoqIGPTryptophan synthase alpha chain/0.453
1toiHCIAspartate aminotransferase2.6.1.10.453
1yw7A41Methionine aminopeptidase 2/0.453
2fy4COACholine O-acetyltransferase2.3.1.60.453
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.453
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.453
2xviFADPutative flavin-containing monooxygenase/0.453
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.453
4awsFMNNADH:flavin oxidoreductase Sye1/0.453
4eb7PLPCysteine desulfurase IscS 2/0.453
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.453
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.453
4rp8ASCAscorbate-specific PTS system EIIC component/0.453
1kbiFMNCytochrome b2, mitochondrial1.1.2.30.452
1m13HYFNuclear receptor subfamily 1 group I member 2/0.452
1mxfMTXPutative pteridine reductase 2/0.452
1o9bNAIQuinate/shikimate dehydrogenase/0.452
1tojHCIAspartate aminotransferase2.6.1.10.452
2pncCLUPrimary amine oxidase, liver isozyme/0.452
2wqpWQPPolysialic acid capsule biosynthesis protein SiaC/0.452
3atzFMNProstaglandin F2a synthase/0.452
3zhsTD6Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.452
4a84DXCMajor pollen allergen Bet v 1-A/0.452
4a8v2ANMajor pollen allergen Bet v 1-J/0.452
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.451
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.451
1rfuADPPyridoxal kinase2.7.1.350.451
1u1d181Uridine phosphorylase2.4.2.30.451
2dvlFADAcyl-CoA dehydrogenase/0.451
2vkeTACTetracycline repressor protein class D/0.451
3aezGDPPantothenate kinase2.7.1.330.451
3akm11DFatty acid-binding protein, intestinal/0.451
3kruFMNNADH:flavin oxidoreductase/NADH oxidase/0.451
3p67FMNPentaerythritol tetranitrate reductase/0.451
3u57DH8Raucaffricine-O-beta-D-glucosidase3.2.1.1250.451
4h6pFMNChromate reductase/0.451
4zj8SUVOrexin receptor type 1/0.451
1bim0QBRenin3.4.23.150.450
1ja0FADNADPH--cytochrome P450 reductase/0.450
1kp2ATPArgininosuccinate synthase6.3.4.50.450
1sq5ADPPantothenate kinase2.7.1.330.450
2igoFADPyranose 2-oxidase/0.450
3atyFMNProstaglandin F2a synthase/0.450
3k8q22APurine nucleoside phosphorylase2.4.2.10.450
4bfyZVYPantothenate kinase2.7.1.330.450
4loi1YCStimulator of interferon genes protein/0.450
1icqOPD12-oxophytodienoate reductase 11.3.1.420.449
1ld8U49Protein farnesyltransferase subunit beta2.5.1.580.449
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.449
2g1r3IGRenin3.4.23.150.449
2pobGW4Peroxisome proliferator-activated receptor gamma/0.449
2qw034Z4-chlorobenzoyl CoA ligase/0.449
2uuoLK3UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.449
2z1qFADAcyl-CoA dehydrogenase/0.449
3biy01KHistone acetyltransferase p300/0.449
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3fr28CAFatty acid-binding protein, adipocyte/0.449
3g70A5TRenin3.4.23.150.449
3t3r9PLCytochrome P450 2A61.14.130.449
3uayADNPurine nucleoside phosphorylase DeoD-type/0.449
4a802ANMajor pollen allergen Bet v 1-A/0.449
4awtFMNNADH:flavin oxidoreductase Sye1/0.449
4bb3KKAIsopenicillin N synthase1.21.3.10.449
1bdmNAXMalate dehydrogenase/0.448
1f4eTPRThymidylate synthase/0.448
1tgv5UDUridine phosphorylase2.4.2.30.448
2dg4RAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.448
2dxdANPNucleoside diphosphate kinase2.7.4.60.448
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.448
2gqaFMNNADH:flavin oxidoreductase Sye1/0.448
2jb4A14Isopenicillin N synthase1.21.3.10.448
2vatCOAAcetyl-CoA--deacetylcephalosporin C acetyltransferase2.3.1.1750.448
2xdaJPS3-dehydroquinate dehydratase4.2.1.100.448
2xveFADPutative flavin-containing monooxygenase/0.448
3c35KAIGlutamate receptor ionotropic, kainate 1/0.448
3zbzOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.448
4bfwZVWPantothenate kinase2.7.1.330.448
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.448
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.448
1eioGCHGastrotropin/0.447
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.447
1o6qR17Squalene--hopene cyclase4.2.1.1290.447
1t9gFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.447
1w34FADFerredoxin--NADP reductase1.18.1.20.447
2gouFMNNADH:flavin oxidoreductase Sye1/0.447
2j3qTFLAcetylcholinesterase3.1.1.70.447
2ofiADK3-methyladenine DNA glycosylase I/0.447
2wzwNDPNitroreductase NfnB/0.447
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.447
3da24MDCarbonic anhydrase 134.2.1.10.447
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.447
3fr4F8AFatty acid-binding protein, adipocyte/0.447
3ivgFG5Pantothenate synthetase6.3.2.10.447
3oetNADErythronate-4-phosphate dehydrogenase/0.447
4fxy0W2Neurolysin, mitochondrial3.4.24.160.447
4ockANPN-acetylhexosamine 1-kinase2.7.1.1620.447
4psbGA3Cytokinin-specific binding protein/0.447
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.447
1e2nRCAThymidine kinase/0.446
1esnANPPantothenate kinase2.7.1.330.446
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.446
1rszDIHPurine nucleoside phosphorylase2.4.2.10.446
1rx8FOLDihydrofolate reductase1.5.1.30.446
1towCRZFatty acid-binding protein, adipocyte/0.446
1x1aSAMC-20 methyltransferase/0.446
1xddAAYIntegrin alpha-L/0.446
1zg32HIIsoflavone 4'-O-methyltransferase/0.446
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.446
2g8yNADHydroxycarboxylate dehydrogenase B/0.446
2il2LIXRenin3.4.23.150.446
2nq8ZIDEnoyl-ACP reductase/0.446
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.446
2xvfFADPutative flavin-containing monooxygenase/0.446
2zbaZBATrichothecene 3-O-acetyltransferase/0.446
3bj8COADiamine acetyltransferase 1/0.446
3junAJDPhenazine biosynthesis protein A/B/0.446
3sfy3FYUncharacterized protein/0.446
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase/0.446
4c49HCYCorticosteroid-binding globulin/0.446
4frkDWDBeta-secretase 13.4.23.460.446
4i1iNADMalate dehydrogenase/0.446
4q71FADBifunctional protein PutA/0.446
1j9zFADNADPH--cytochrome P450 reductase/0.445
1qtqQSIGlutamine--tRNA ligase6.1.1.180.445
1r2jFADFkbI/0.445
1xvaSAMGlycine N-methyltransferase2.1.1.200.445
2cmoM1LGlutamate receptor 2/0.445
2iviACWIsopenicillin N synthase1.21.3.10.445
2jizANPATP synthase subunit beta, mitochondrial3.6.3.140.445
2rlcCHDCholoylglycine hydrolase3.5.1.240.445
2zvbSAHPrecorrin-3 C17-methyltransferase/0.445
3f63GTXGlutathione transferase GST1-4/0.445
3fhxPLPPyridoxal kinase2.7.1.350.445
3hf3FMNChromate reductase/0.445
3ixp834Ecdysone receptor/0.445
3junAKDPhenazine biosynthesis protein A/B/0.445
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.445
3qftFADNADPH--cytochrome P450 reductase/0.445
3qt62P0Mevalonate diphosphate decarboxylase/0.445
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.445
4lutDCSAlanine racemase/0.445
4v12POGMaoC like domain protein/0.445
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.444
1akaPLPAspartate aminotransferase, mitochondrial2.6.1.10.444
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.444
1bzmMZMCarbonic anhydrase 14.2.1.10.444
1ex75GPGuanylate kinase2.7.4.80.444
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.444
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.444
1psa0ZLPepsin A3.4.23.10.444
1rd7FOLDihydrofolate reductase1.5.1.30.444
1uxjNADMalate dehydrogenase/0.444
2cekN8TAcetylcholinesterase3.1.1.70.444
2fk8SAMHydroxymycolate synthase MmaA42.1.10.444
2hk9NAPShikimate dehydrogenase (NADP(+))/0.444
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.444
2iyfERYOleandomycin glycosyltransferase2.4.10.444
2vkvTDCTetracycline repressor protein class D/0.444
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.444
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3pl8FADPyranose 2-oxidase/0.444
3zhuTD8Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.444
3zoiM2WIsopenicillin N synthase1.21.3.10.444
4e2dFMNDehydrogenase/0.444
1vjtNADAlpha-glucosidase, putative/0.443
1xe55FEPlasmepsin-23.4.23.390.443
1xs7MMIBeta-secretase 13.4.23.460.443
1y9dTPPPyruvate oxidase1.2.3.30.443
2a5kAZPReplicase polyprotein 1ab3.4.220.443
2lfoGCHFatty acid-binding protein, liver/0.443
2nnqT4BFatty acid-binding protein, adipocyte/0.443
2v59LZKBiotin carboxylase6.3.4.140.443
3imgBZ2Pantothenate synthetase6.3.2.10.443
3mjrAC2Deoxycytidine kinase2.7.1.740.443
4gd40WSLysine-specific demethylase 4A1.14.110.443
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.443
4tqgNDPPutative dTDP-d-glucose 4 6-dehydratase/0.443
4usqFADPyridine nucleotide-disulfide oxidoreductase/0.443
1kvsUPGUDP-glucose 4-epimerase5.1.3.20.442
1udaUFGUDP-glucose 4-epimerase5.1.3.20.442
2ohvNHLGlutamate racemase/0.442
2qc8ADPGlutamine synthetase6.3.1.20.442
2w9hTOPDihydrofolate reductase1.5.1.30.442
3d4pNADL-lactate dehydrogenase 11.1.1.270.442
3fpaDTBATP-dependent dethiobiotin synthetase BioD/0.442
3maaFKPAdenylate cyclase type 2/0.442
3maaFKPAdenylate cyclase type 5/0.442
3mauPLRPutative sphingosine-1-phosphate lyase/0.442
3v0p4GWHisto-blood group ABO system transferase/0.442
3ziuLSSLeucyl-tRNA synthetase/0.442
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.442
4djw0KPBeta-secretase 13.4.23.460.442
4ej1FOLDihydrofolate reductase1.5.1.30.442
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.442
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.442
4m0f1YKAcetylcholinesterase3.1.1.70.442
4x28FDAAcyl-CoA dehydrogenase FadE26/0.442
4x28FDAAcyl-CoA dehydrogenase FadE27/0.442
5czySAMEukaryotic huntingtin interacting protein B/0.442
1c7oPPGHemolysin/0.441
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.441
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.441
2v16C47Renin3.4.23.150.441
2z3nPHE_ARG_TYR_LEU_GLYLeucyl/phenylalanyl-tRNA--protein transferase2.3.2.60.441
3akn11DFatty acid-binding protein, intestinal/0.441
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.441
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.441
3p8jFMNPentaerythritol tetranitrate reductase/0.441
3sl2ATPSensor histidine kinase WalK/0.441
3wagTYDGlycosyltransferase/0.441
4bis8HQLysine-specific demethylase 4A1.14.110.441
4ca83ESAngiotensin-converting enzyme3.4.15.10.441
4dbs0HVAldo-keto reductase family 1 member C3/0.441
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
4l0qNADAlcohol dehydrogenase class-3/0.441
4mdhNADMalate dehydrogenase, cytoplasmic1.1.1.370.441
4rvfTYDD-mycarose 3-C-methyltransferase/0.441
4v2gITCTetracycline repressor protein class D/0.441
4wdfA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.441
4yj2GTPTubulin alpha-1B chain/0.441
6gsuGPSGlutathione S-transferase Mu 12.5.1.180.441
1a5bIGPTryptophan synthase alpha chain/0.440
1ee9NADMethylenetetrahydrofolate dehydrogenase [NAD(+)]1.5.1.150.440
1egeFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.440
1h60STRPentaerythritol tetranitrate reductase/0.440
1icsFMN12-oxophytodienoate reductase 11.3.1.420.440
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.440
1rzuADPGlycogen synthase 12.4.1.210.440
1wxjIPLTryptophan synthase alpha chain/0.440
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.440
2e77FMNLactate oxidase/0.440
2j07HDFDeoxyribodipyrimidine photo-lyase4.1.99.30.440
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.440
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.440
2wu4HBPAcetylcholinesterase3.1.1.70.440
3af1GDPPantothenate kinase2.7.1.330.440
3aw9GDUNAD-dependent epimerase/dehydratase/0.440
3eksCY9Actin-5C/0.440
3gfbNADL-threonine 3-dehydrogenase/0.440
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.440
3mj4FADUDP-galactopyranose mutase/0.440
3p84FMNPentaerythritol tetranitrate reductase/0.440
3pd4A3GThreonine--tRNA ligase6.1.1.30.440
3tjzGNPADP-ribosylation factor 1/0.440
3wyqBTNStreptavidin/0.440
4ehyADPTetraacyldisaccharide 4'-kinase/0.440
4j1k1HGBeta-secretase 13.4.23.460.440
4y17LAETranscriptional regulator of ftsQAZ gene cluster/0.440
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.440