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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3m50EBT14-3-3-like protein C

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3m50EBT14-3-3-like protein C/1.000
3m50EBTPlasma membrane ATPase/1.000
4bebATPType I restriction enzyme EcoR124II R protein3.1.21.30.482
5dstSAHProtein arginine N-methyltransferase 82.1.10.478
4i3p1CW3-hydroxyanthranilate 3,4-dioxygenase/0.473
4becATPType I restriction enzyme EcoR124II R protein3.1.21.30.470
1rs6DP2Nitric oxide synthase, brain1.14.13.390.454
4s1b2BALmo1466 protein/0.453
4xjxATPType I restriction enzyme EcoR124II R protein3.1.21.30.453
2puiADPMethylthioribose kinase2.7.1.1000.450
1zzqDP9Nitric oxide synthase, brain1.14.13.390.449
3ka7FADPutative oxidoreductase/0.449
1i9c5ADGlutamate mutase epsilon subunit/0.442