Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.11.000
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.11.000
5a0yCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.718
5a0yCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.718
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.639
3m30COMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.639
3m30COMMethyl-coenzyme M reductase I subunit beta2.8.4.10.639
3m2uCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.628
3m2rCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.511
3m2rCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.511
1e6vCOMMethyl-coenzyme M reductase I subunit alpha/0.476
1e6vCOMMethyl coenzyme M reductase, beta subunit/0.476
1bwsNDPGDP-L-fucose synthase/0.471
4g3jVNTLanosterol 14-alpha-demethylase/0.466
1xe65FPPlasmepsin-23.4.23.390.462
1x1bSAHC-20 methyltransferase/0.461
2g1s4IGRenin3.4.23.150.461
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.460
4ipw1G7Mycocyclosin synthase1.14.21.90.458
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.457
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.456
3qt62P0Mevalonate diphosphate decarboxylase/0.455
2g1y5IGRenin3.4.23.150.454
3gw9VNILanosterol 14-alpha-demethylase/0.453
3tjzGNPADP-ribosylation factor 1/0.453
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.453
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.451
4g7gVFVLanosterol 14-alpha-demethylase/0.450
3p62FMNPentaerythritol tetranitrate reductase/0.449
5a0112VO-glycosyltransferase/0.449
3lqfNADGalactitol dehydrogenase/0.448
4loi1YCStimulator of interferon genes protein/0.448
1l7x700Glycogen phosphorylase, liver form2.4.1.10.447
1x1aSAMC-20 methyltransferase/0.446
3tr05GPGuanylate kinase/0.446
2dftADPShikimate kinase2.7.1.710.445
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.444
1xe55FEPlasmepsin-23.4.23.390.443
2gjlFMNNitronate monooxygenase1.13.12.160.443
2gv8NDPThiol-specific monooxygenase1.14.130.443
4lutDCSAlanine racemase/0.443
4uymVOR14-alpha sterol demethylase Cyp51B/0.443
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.442
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.442
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.442
3zeiAWHO-acetylserine sulfhydrylase/0.442
4bfzZVZPantothenate kinase2.7.1.330.442
2ft9CHDFatty acid-binding protein 2, liver/0.440
2g1n1IGRenin3.4.23.150.440
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.440