sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3lqf | NAD | Galactitol dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3lqf | NAD | Galactitol dehydrogenase | / | 1.000 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.509 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.494 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.488 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.482 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.475 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.474 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.472 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.472 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.468 | |
| 4qec | NAP | ElxO | / | 0.467 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.465 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.465 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.460 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.459 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.457 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.456 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.452 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.450 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.447 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.447 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.447 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.447 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.446 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.445 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.444 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.442 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.441 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.440 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.440 |