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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3liqE14Protease

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3liqE14Protease/1.000
3litE15Protease/0.735
3livE16Protease/0.690
3linE13Protease/0.658
3lixE17Protease/0.597
3wsjMK1Protease/0.570
4hdfG52Gag-Pol polyprotein3.4.23.160.558
1vikBAYGag-Pol polyprotein/0.539
1difA85Gag-Pol polyprotein/0.535
4kb9G79Protease/0.535
1ec3MS3Gag-Pol polyprotein3.4.23.160.533
3nxe2NCProtease/0.532
2qd6065Gag-Pol polyprotein3.4.23.160.531
3kdcJZPGag-Pol polyprotein3.4.23.160.531
1hvsA77Gag-Pol polyprotein/0.527
3tl9ROCGag-Pol polyprotein3.4.23.160.526
1hvjA78Gag-Pol polyprotein/0.525
2aquDR7Gag-Pol polyprotein3.4.23.160.523
4ye3G04Gag-Pol polyprotein3.4.23.160.523
2p3d3TLProtease/0.520
3zptM8YGag-Pol polyprotein3.4.23.160.520
1bv7XV6Gag-Pol polyprotein3.4.23.160.519
2ieo017Protease/0.519
2pk5075Protease/0.519
3a2oKNJGag-Pol polyprotein3.4.23.160.518
1ec2BEJGag-Pol polyprotein3.4.23.160.517
2fxdDR7Pol polyprotein/0.517
2qnnQN1Gag-Pol polyprotein3.4.23.160.517
3s85LK0Gag-Pol polyprotein/0.517
1wbk568Pol protein/0.515
2fdd385Pol protein/0.514
3ekqROCGag-Pol polyprotein3.4.23.160.514
3nu9478Gag-Pol polyprotein3.4.23.160.514
3st5G89Gag-Pol polyprotein3.4.23.160.514
2uy0HV1Gag-Pol polyprotein3.4.23.160.511
3ggaGGWGag-Pol polyprotein/0.511
2bpv1INGag-Pol polyprotein3.4.23.160.510
2cem2AHPol protein/0.510
3sa755AProtease/0.510
4j55031Gag-Pol polyprotein3.4.23.160.510
3vfb031Gag-Pol polyprotein3.4.23.160.509
4a6bQG8Gag-Pol polyprotein3.4.23.160.509
4rvj478Protease/0.509
2a4fAAUV-1 protease/0.508
2rkfAB1Pol protein/0.508
2aoe0Q4Gag-Pol polyprotein3.4.23.160.507
3ekp478Gag-Pol polyprotein3.4.23.160.507
3ggxGGXGag-Pol polyprotein/0.507
4hdpG52Gag-Pol polyprotein3.4.23.160.507
1hiv1ZKGag-Pol polyprotein/0.506
2nmyROCProtease/0.506
2nnkROCProtease/0.506
3dk1G05Gag-Pol polyprotein3.4.23.160.506
4qgiROCGag-Pol polyprotein3.4.23.160.506
1yt9OISGag-Pol polyprotein/0.505
2bqvA1AProtease/0.505
2p3b3TLV-1 PROTEASE protein/0.505
2p3b3TLV-1 protease/0.505
2qi3MZ5Gag-Pol polyprotein/0.505
4a4qUX9Pol protein/0.505
4njvRITProtease/0.505
1ivp1ZKGag-Pol polyprotein/0.504
2cen4AHProtease/0.504
3vfa031Gag-Pol polyprotein3.4.23.160.504
3zpuM8BGag-Pol polyprotein3.4.23.160.504
4a6cQG9Gag-Pol polyprotein3.4.23.160.504
3ndxRITGag-Pol polyprotein3.4.23.160.503
2fde385Gag-Pol polyprotein3.4.23.160.502
2pk6O33V-1 protease/0.502
2qd8065Gag-Pol polyprotein3.4.23.160.502
3em4DR7Gag-Pol polyprotein3.4.23.160.502
3vf5031Gag-Pol polyprotein3.4.23.160.502
2xyfG40Gag-Pol polyprotein/0.501
3zpsEQMGag-Pol polyprotein3.4.23.160.501
1c6zROCProtease/0.500
1xl5190Gag-Pol polyprotein3.4.23.160.500
3d1yROCGag-Pol polyprotein3.4.23.160.500
3kf03TLGag-Pol polyprotein/0.500
1hvkA79Gag-Pol polyprotein/0.499
2fxeDR7Gag-Pol polyprotein3.4.23.160.499
2uxzHI1Gag-Pol polyprotein3.4.23.160.499
3ekwDR7Gag-Pol polyprotein3.4.23.160.499
3ndtROCGag-Pol polyprotein3.4.23.160.499
4djqM86Pol polyprotein/0.499
1hxwRITGag-Pol polyprotein/0.498
1rl8RITGag-Pol polyprotein3.4.23.160.498
2bpy3INGag-Pol polyprotein3.4.23.160.498
3bgbLJGGag-Pol polyprotein3.4.23.160.498
3nduROCGag-Pol polyprotein3.4.23.160.498
1w5yBE6Gag-Pol polyprotein3.4.23.160.497
2i4xKGQProtease/0.497
3jvwDMPGag-Pol polyprotein3.4.23.160.497
3oxxDR7Gag-Pol polyprotein3.4.23.160.497
3uhl2NCGag-Pol polyprotein3.4.23.160.497
1d4sTPVGag-Pol polyprotein3.4.23.160.496
1wbmBLLPol protein/0.496
3ndwRITGag-Pol polyprotein3.4.23.160.496
3nyg2NCGag-Pol polyprotein3.4.23.160.496
1d4yTPVGag-Pol polyprotein3.4.23.160.495
1hviA77Protease/0.495
1vijBAYGag-Pol polyprotein/0.495
2pqzG0GGag-Pol polyprotein3.4.23.160.495
3djkG55Gag-Pol polyprotein3.4.23.160.495
3i2l2NCProtease/0.495
1fg62NCGag-Pol polyprotein3.4.23.160.494
1hihC20Gag-Pol polyprotein/0.494
1sdvMK1Gag-Pol polyprotein3.4.23.160.494
2f81017Gag-Pol polyprotein3.4.23.160.494
3kddJZQGag-Pol polyprotein3.4.23.160.494
3kfr3TLGag-Pol polyprotein/0.494
1a9mU0EGag-Pol polyprotein/0.493
2bpz3INGag-Pol polyprotein3.4.23.160.493
2p3a3TLPol protein/0.493
2xyeCXGGag-Pol polyprotein/0.493
3cktYDPGag-Pol polyprotein3.4.23.160.493
3d1z017Gag-Pol polyprotein3.4.23.160.493
3ekt017Gag-Pol polyprotein3.4.23.160.493
3el51UNGag-Pol polyprotein/0.493
3oxv478Gag-Pol polyprotein3.4.23.160.493
4djoMK5Pol polyprotein/0.493
3cyxROCGag-Pol polyprotein3.4.23.160.492
3mxeK54Gag-Pol polyprotein3.4.23.160.492
3nwq2NCGag-Pol polyprotein3.4.23.160.492
3oxcROCProtease/0.492
4hdbG52Gag-Pol polyprotein3.4.23.160.492
1w5xBE5Gag-Pol polyprotein3.4.23.160.491
2hb3GRLProtease/0.491
3dcrKVSProtease/0.491
3hzc2NCProtease/0.491
3qn8NI7Gag-Pol polyprotein3.4.23.160.491
4hegG52Gag-Pol polyprotein3.4.23.160.491
1zsr0ZTGag-Pol polyprotein3.4.23.160.490
2a1eIPFGag-Pol polyprotein3.4.23.160.490
2qhcAB1Protease/0.490
3d1xROCGag-Pol polyprotein3.4.23.160.490
3pwrROCGag-Pol polyprotein3.4.23.160.490
3sa323XProtease/0.490
1t7i017Gag-Pol polyprotein3.4.23.160.489
2f3kRO1Protease/0.489
3jw2017Gag-Pol polyprotein3.4.23.160.489
3sa4F72Protease/0.489
1bwaXV6Gag-Pol polyprotein3.4.23.160.488
1ffi2NCGag-Pol polyprotein3.4.23.160.488
2f80017Gag-Pol polyprotein3.4.23.160.488
2wkz5AHGag-Pol polyprotein/0.488
3kfn3TLGag-Pol polyprotein/0.488
4djpM73Pol polyprotein/0.488
1b6kPI5Gag-Pol polyprotein3.4.23.160.487
1ohr1UNV-1 PROTEASE protein/0.487
2bpw1INGag-Pol polyprotein3.4.23.160.487
2idw017Protease/0.487
2wl05AHGag-Pol polyprotein/0.487
3sa5A69Protease/0.487
1ebwBEIGag-Pol polyprotein3.4.23.160.486
1idb0DOGag-Pol polyprotein/0.486
1w5vBE3Gag-Pol polyprotein3.4.23.160.486
2cej1AHPol protein/0.486
2qnqQN3Gag-Pol polyprotein3.4.23.160.486
3em6017Gag-Pol polyprotein3.4.23.160.486
1daz0Q4Gag-Pol polyprotein3.4.23.160.485
1hvrXK2Gag-Pol polyprotein/0.485
1t7kBH0Gag-Pol polyprotein3.4.23.160.485
3sa6F71Protease/0.485
3sa9A68Protease/0.485
4njsG08Protease/0.485
1t7j478Gag-Pol polyprotein3.4.23.160.484
2b7zMK1Gag-Pol polyprotein/0.484
2f8g017Gag-Pol polyprotein3.4.23.160.484
2i4wKGQProtease/0.484
2qci065Gag-Pol polyprotein3.4.23.160.484
3ttp017Gag-Pol polyprotein3.4.23.160.484
1hshMK1Gag-Pol polyprotein/0.483
1hvlA76Gag-Pol polyprotein/0.483
2avm2NCGag-Pol polyprotein3.4.23.160.483
2upjU02Gag-Pol polyprotein3.4.23.160.483
3ok9G52Gag-Pol polyprotein3.4.23.160.483
3s54017Protease/0.483
3saa77FProtease/0.483
3sabF78Protease/0.483
3sacAF8Protease/0.483
7upjINUGag-Pol polyprotein3.4.23.160.483
1hpoUNIGag-Pol polyprotein3.4.23.160.482
2hc0AB2Protease/0.482
2i4vDJRV-1 protease/0.482
3fx5KNIGag-Pol polyprotein3.4.23.160.482
4djr0KJPol polyprotein/0.482
1k2b0Q4Gag-Pol polyprotein3.4.23.160.481
1mesDMPGag-Pol polyprotein3.4.23.160.481
1tcxIM1Gag-Pol polyprotein3.4.23.160.481
3el4ROCGag-Pol polyprotein3.4.23.160.481
4njt017Protease/0.481
1d4kPI8Gag-Pol polyprotein3.4.23.160.480
1k1u0Q4Gag-Pol polyprotein3.4.23.160.480
1sguMK1Gag-Pol polyprotein3.4.23.160.480
3jvy017Gag-Pol polyprotein3.4.23.160.480
3o9bK2APol polyprotein/0.480
1ec0BEDGag-Pol polyprotein3.4.23.160.479
1hxbROCGag-Pol polyprotein3.4.23.160.479
1jld0PPGag-Pol polyprotein/0.479
3em3478Gag-Pol polyprotein3.4.23.160.479
3gi6D78Gag-Pol polyprotein/0.479
3qbfJHGGag-Pol polyprotein3.4.23.160.479
3qrmNK7Gag-Pol polyprotein3.4.23.160.479
4j5j478Gag-Pol polyprotein3.4.23.160.479
1ida0POGag-Pol polyprotein3.4.23.470.478
2r5q1UNGag-Pol polyprotein/0.478
3bgcLJHGag-Pol polyprotein3.4.23.160.478
3el9DR7Gag-Pol polyprotein3.4.23.160.478
3k4vROCGag-Pol polyprotein3.4.23.160.478
3nls016Gag-Pol polyprotein3.4.23.160.478
3nuo478Gag-Pol polyprotein3.4.23.160.478
1fg80Q4Gag-Pol polyprotein3.4.23.160.477
1fgc2NCGag-Pol polyprotein3.4.23.160.477
2q5kAB1Protease/0.477
3nu6478Gag-Pol polyprotein3.4.23.160.477
3o9cK20Pol polyprotein/0.477
4dfg0JVGag-Pol polyprotein3.4.23.160.477
4njuTPVProtease/0.477
1b6mPI6Gag-Pol polyprotein3.4.23.160.476
2ien017Gag-Pol polyprotein3.4.23.160.476
2pyn1UNGag-Pol polyprotein3.4.23.160.476
2r38G4GGag-Pol polyprotein3.4.23.160.476
4k4p3TLGag-Pol polyprotein/0.476
3ekv478Gag-Pol polyprotein3.4.23.160.475
3s43478Protease/0.475
9hvp0E9Gag-Pol polyprotein/0.475
1muiAB1Protease/0.474
1n49RITGag-Pol polyprotein3.4.23.160.474
1odw0E8Gag-Pol polyprotein3.4.23.160.474
1qbsDMPGag-Pol polyprotein3.4.23.160.474
1sdtMK1Gag-Pol polyprotein3.4.23.160.474
2aidTHKGag-Pol polyprotein3.4.23.160.474
2bb9AKCGag-Pol polyprotein3.4.23.160.474
2qd7065Gag-Pol polyprotein3.4.23.160.474
4q1y017Gag-Pol polyprotein3.4.23.160.474
1ec1BEEGag-Pol polyprotein3.4.23.160.473
1iziQ50Gag-Pol polyprotein3.4.23.160.473
1sbgIM1Gag-Pol polyprotein/0.473
2qi7MZ9Gag-Pol polyprotein/0.473
3ekyDR7Gag-Pol polyprotein3.4.23.160.473
3gi4K60Gag-Pol polyprotein/0.473
3qrsNK8Gag-Pol polyprotein3.4.23.160.473
1ajvNMBGag-Pol polyprotein3.4.23.160.472
1d4lPI9Gag-Pol polyprotein3.4.23.160.472
1ebyBEBGag-Pol polyprotein3.4.23.160.472
1fej2NCGag-Pol polyprotein3.4.23.160.472
1ff02NCGag-Pol polyprotein3.4.23.160.472
1hsgMK1Gag-Pol polyprotein/0.472
2qak1UNGag-Pol polyprotein3.4.23.160.472
3qaaG04Gag-Pol polyprotein3.4.23.160.472
3tog079Gag-Pol polyprotein2.7.7.490.472
4i8zG08Gag-Pol polyprotein3.4.23.160.472
1msmJE2Gag-Pol polyprotein3.4.23.160.471
2p3c3TLProtease/0.471
2pym1UNGag-Pol polyprotein3.4.23.160.471
3kfs3TLGag-Pol polyprotein/0.471
3mws017Pol protein/0.471
3o9gF53Gag-Pol polyprotein/0.471
1t3r017Gag-Pol polyprotein3.4.23.160.470
2qi6MZ8Gag-Pol polyprotein/0.470
2r3tG4GGag-Pol polyprotein3.4.23.160.470
3bvb017Gag-Pol polyprotein3.4.23.160.470
3cyw017Gag-Pol polyprotein3.4.23.160.470
1zsf0ZSGag-Pol polyprotein3.4.23.160.469
2qi5MZ7Gag-Pol polyprotein/0.469
2z54AB1Gag-Pol polyprotein3.4.23.160.469
3nu4478Gag-Pol polyprotein3.4.23.160.469
3qp0NI8Gag-Pol polyprotein3.4.23.160.469
1d4iBEGGag-Pol polyprotein3.4.23.160.468
1dw60Q4Gag-Pol polyprotein3.4.23.160.468
3lzv017Gag-Pol polyprotein3.4.23.160.468
2qnpQN2Gag-Pol polyprotein3.4.23.160.467
3slz3TLPutative gag-pro-pol polyprotein/0.467
3t3c017Gag-Pol polyprotein3.4.23.160.467
3ufnROCGag-Pol polyprotein/0.467
4dqh017Gag-Pol polyprotein/0.467
1ebzBECGag-Pol polyprotein3.4.23.160.466
1hiiC20Gag-Pol polyprotein/0.466
1hpxKNIGag-Pol polyprotein/0.466
1msnJE2Gag-Pol polyprotein3.4.23.160.466
2r43G3GGag-Pol polyprotein3.4.23.160.466
3ucb017Gag-Pol polyprotein/0.466
4dqe017Gag-Pol polyprotein/0.466
1bai0Q4Gag-Pro polyprotein/0.465
1d4jMSCGag-Pol polyprotein3.4.23.160.465
1iiq0ZRGag-Pol polyprotein3.4.23.160.465
3ggu017Gag-Pol polyprotein3.4.23.160.465
3lzu017Gag-Pol polyprotein3.4.23.160.465
1a8g2Z4Gag-Pol polyprotein3.4.23.160.464
1c6x3INProtease/0.464
1mtrPI6Gag-Pol polyprotein3.4.23.160.464
1z1hHBBGag-Pol polyprotein3.4.23.160.464
2qhzMZ2Gag-Pol polyprotein/0.464
3aidARQGag-Pol polyprotein3.4.23.160.464
1g35AHFGag-Pol polyprotein3.4.23.160.463
1hosPHPGag-Pol polyprotein/0.463
1meuDMPGag-Pol polyprotein3.4.23.160.463
1qbrXV6Gag-Pol polyprotein3.4.23.160.463
1qbu846Gag-Pol polyprotein3.4.23.160.463
1sh9RITGag-Pol polyprotein3.4.23.160.463
2hs1017Protease/0.463
2nnpROCProtease/0.463
2q641UNGag-Pol polyprotein3.4.23.160.463
2qhyMZ1Gag-Pol polyprotein/0.463
4dqc017Gag-Pol polyprotein/0.463
3o9dK19Pol polyprotein/0.462
3oxw017Gag-Pol polyprotein3.4.23.160.462
1d4hBEHGag-Pol polyprotein3.4.23.160.461
1hpv478Gag-Pol polyprotein/0.461
1metDMPGag-Pol polyprotein3.4.23.160.461
1sduMK1Gag-Pol polyprotein3.4.23.160.461
1z1rHBHGag-Pol polyprotein3.4.23.160.461
2b60RITPol polyprotein/0.461
2i4dQFIProtease/0.461
3o9fK2DGag-Pol polyprotein/0.461
3pwm017Gag-Pol polyprotein3.4.23.160.461
3vf7031Gag-Pol polyprotein3.4.23.160.461
4dqf017Gag-Pol polyprotein/0.461
2avsMK1Gag-Pol polyprotein3.4.23.160.460
2avvMK1Gag-Pol polyprotein3.4.23.160.460
2r3wG3GGag-Pol polyprotein3.4.23.160.460
3oy4017Gag-Pol polyprotein3.4.23.160.460
3s56ROCProtease/0.460
3sa8K83Protease/0.460
1kzkJE2Gag-Pol polyprotein3.4.23.160.459
2r5pMK1Gag-Pol polyprotein/0.459
3el1DR7Gag-Pol polyprotein3.4.23.160.459
3i6oGR6Gag-Pol polyprotein3.4.23.160.459
3nwxKVSGag-Pol polyprotein3.4.23.160.459
1a8k0Q4Gag-Pol polyprotein3.4.23.160.458
1proA88Gag-Pol polyprotein/0.458
2hs2017Protease/0.458
2i4uDJRProtease/0.458
3bva2NCGag-Pol polyprotein3.4.23.160.458
3el01UNGag-Pol polyprotein3.4.23.160.458
3o9iA61Gag-Pol polyprotein/0.458
3ogqAB1Pol polyprotein/0.458
2q54MU1Protease/0.457
1qbt146Gag-Pol polyprotein3.4.23.160.456
1bdrIM1Gag-Pol polyprotein3.4.23.160.455
1k2c0Q4Gag-Pol polyprotein3.4.23.160.455
1npa3NHGag-Pol polyprotein3.4.23.160.455
1npwLGZGag-Pol polyprotein3.4.23.160.455
2q631UNGag-Pol polyprotein3.4.23.160.455
1b6lPI4Gag-Pol polyprotein3.4.23.160.454
2qi4MZ6Gag-Pol polyprotein/0.454
3dckKVIProtease/0.454
4j54G52Gag-Pol polyprotein3.4.23.160.454
1fff0Q4Gag-Pol polyprotein3.4.23.160.453
1mrxK57Gag-Pol polyprotein3.4.23.160.453
3nu3478Gag-Pol polyprotein3.4.23.160.453
1a940Q4Gag-Pol polyprotein3.4.23.160.452
2bbbHH1Gag-Pol polyprotein3.4.23.160.452
2pwcG3GGag-Pol polyprotein3.4.23.160.452
3nu5478Gag-Pol polyprotein3.4.23.160.452
1c70L75Protease/0.451
1hwr216Gag-Pol polyprotein3.4.23.160.451
2fleAIProtease/0.451
3mxdK53Gag-Pol polyprotein3.4.23.160.451
3o9eA60Pol polyprotein/0.451
1g2kNM1Gag-Pol polyprotein3.4.23.160.450
3d20017Gag-Pol polyprotein3.4.23.160.450
3i7eDJRGag-Pol polyprotein/0.450
3o9hK2EGag-Pol polyprotein/0.450
3qpjN4IGag-Pol polyprotein3.4.23.160.450
3qroNK9Gag-Pol polyprotein3.4.23.160.450
1odyLP1Gag-Pol polyprotein3.4.23.160.449
1c6yMK1Protease/0.448
1npvL27Gag-Pol polyprotein3.4.23.160.448
2o4pTPVProtease/0.448
2z4o065Gag-Pol polyprotein3.4.23.160.448
1hbvGANGag-Pol polyprotein/0.447
1m0b0ZQGag-Pol polyprotein3.4.23.160.447
1sivPSIGag-Pol polyprotein/0.447
2psuMUUProtease/0.447
2qi0MZ3Gag-Pol polyprotein/0.447
3o9aK14Pol polyprotein/0.447
4hla017Gag-Pol polyprotein3.4.23.160.447
3gi5K62Gag-Pol polyprotein/0.446
4dqb017Gag-Pol polyprotein/0.446
1b6pPI7Gag-Pol polyprotein3.4.23.160.445
2q3kMUWGag-Pol polyprotein/0.445
3ekx1UNGag-Pol polyprotein3.4.23.160.445
2qi1MZ4Gag-Pol polyprotein/0.443
1bwb146Gag-Pol polyprotein3.4.23.160.442
1izhQ50Protease/0.442
1k6vXN2Gag-Pol polyprotein3.4.23.160.442
3nuj478Gag-Pol polyprotein3.4.23.160.442
1bv9XV6Gag-Pol polyprotein3.4.23.160.441
2pwrG4GGag-Pol polyprotein3.4.23.160.441
2i0dMUTProtease/0.440
3so9017Pol protein/0.440