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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3linE13Protease

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3linE13Protease/1.000
3liqE14Protease/0.628
3livE16Protease/0.618
3litE15Protease/0.569
3wsjMK1Protease/0.546
2qd6065Gag-Pol polyprotein3.4.23.160.528
4kb9G79Protease/0.528
3ekp478Gag-Pol polyprotein3.4.23.160.521
3lixE17Protease/0.520
2aoe0Q4Gag-Pol polyprotein3.4.23.160.518
4hdfG52Gag-Pol polyprotein3.4.23.160.518
1difA85Gag-Pol polyprotein/0.516
1ec2BEJGag-Pol polyprotein3.4.23.160.515
3a2oKNJGag-Pol polyprotein3.4.23.160.514
3kdcJZPGag-Pol polyprotein3.4.23.160.514
2ieo017Protease/0.512
1ec3MS3Gag-Pol polyprotein3.4.23.160.511
1vikBAYGag-Pol polyprotein/0.511
4ye3G04Gag-Pol polyprotein3.4.23.160.510
3tl9ROCGag-Pol polyprotein3.4.23.160.508
2bqvA1AProtease/0.506
2cem2AHPol protein/0.506
2qnnQN1Gag-Pol polyprotein3.4.23.160.506
3ekqROCGag-Pol polyprotein3.4.23.160.505
1hvsA77Gag-Pol polyprotein/0.501
2p3d3TLProtease/0.501
2qi3MZ5Gag-Pol polyprotein/0.500
3s85LK0Gag-Pol polyprotein/0.500
2nmyROCProtease/0.499
2pk5075Protease/0.499
3kf03TLGag-Pol polyprotein/0.499
4hegG52Gag-Pol polyprotein3.4.23.160.498
2aquDR7Gag-Pol polyprotein3.4.23.160.497
3ndtROCGag-Pol polyprotein3.4.23.160.497
3zptM8YGag-Pol polyprotein3.4.23.160.497
2bpv1INGag-Pol polyprotein3.4.23.160.496
1w5yBE6Gag-Pol polyprotein3.4.23.160.495
2fdd385Pol protein/0.495
3em4DR7Gag-Pol polyprotein3.4.23.160.495
3nu9478Gag-Pol polyprotein3.4.23.160.495
2a4fAAUV-1 protease/0.494
2uy0HV1Gag-Pol polyprotein3.4.23.160.494
2xyfG40Gag-Pol polyprotein/0.493
3bgbLJGGag-Pol polyprotein3.4.23.160.493
2bpy3INGag-Pol polyprotein3.4.23.160.492
2qhcAB1Protease/0.492
3ekwDR7Gag-Pol polyprotein3.4.23.160.492
3jw2017Gag-Pol polyprotein3.4.23.160.492
2pk6O33V-1 protease/0.491
3hzc2NCProtease/0.491
1wbk568Pol protein/0.490
3ndxRITGag-Pol polyprotein3.4.23.160.490
1hvjA78Gag-Pol polyprotein/0.489
2fxdDR7Pol polyprotein/0.489
2p3b3TLV-1 PROTEASE protein/0.489
2p3b3TLV-1 protease/0.489
3ggxGGXGag-Pol polyprotein/0.489
4hdbG52Gag-Pol polyprotein3.4.23.160.489
2qd8065Gag-Pol polyprotein3.4.23.160.488
3dk1G05Gag-Pol polyprotein3.4.23.160.488
3ok9G52Gag-Pol polyprotein3.4.23.160.488
3vfb031Gag-Pol polyprotein3.4.23.160.488
4njvRITProtease/0.488
2bpw1INGag-Pol polyprotein3.4.23.160.487
2bpz3INGag-Pol polyprotein3.4.23.160.487
1d4yTPVGag-Pol polyprotein3.4.23.160.486
1zsr0ZTGag-Pol polyprotein3.4.23.160.486
2uxzHI1Gag-Pol polyprotein3.4.23.160.486
3cktYDPGag-Pol polyprotein3.4.23.160.486
3nwq2NCGag-Pol polyprotein3.4.23.160.486
3sa323XProtease/0.486
2a1eIPFGag-Pol polyprotein3.4.23.160.485
3kfr3TLGag-Pol polyprotein/0.485
3nduROCGag-Pol polyprotein3.4.23.160.485
3vf5031Gag-Pol polyprotein3.4.23.160.485
1ivp1ZKGag-Pol polyprotein/0.484
1w5xBE5Gag-Pol polyprotein3.4.23.160.484
1xl5190Gag-Pol polyprotein3.4.23.160.484
2f3kRO1Protease/0.484
2nnkROCProtease/0.484
3d1yROCGag-Pol polyprotein3.4.23.160.484
3ndwRITGag-Pol polyprotein3.4.23.160.484
3zpsEQMGag-Pol polyprotein3.4.23.160.484
4rvj478Protease/0.484
1ffi2NCGag-Pol polyprotein3.4.23.160.483
3d1z017Gag-Pol polyprotein3.4.23.160.483
3ekt017Gag-Pol polyprotein3.4.23.160.483
3s54017Protease/0.483
3sa755AProtease/0.483
3ttp017Gag-Pol polyprotein3.4.23.160.483
1sdvMK1Gag-Pol polyprotein3.4.23.160.482
2i4xKGQProtease/0.482
3oxxDR7Gag-Pol polyprotein3.4.23.160.482
4djqM86Pol polyprotein/0.482
1hshMK1Gag-Pol polyprotein/0.481
1k2b0Q4Gag-Pol polyprotein3.4.23.160.481
1wbmBLLPol protein/0.481
3vfa031Gag-Pol polyprotein3.4.23.160.481
4djr0KJPol polyprotein/0.481
4hdpG52Gag-Pol polyprotein3.4.23.160.481
1w5vBE3Gag-Pol polyprotein3.4.23.160.480
2i4wKGQProtease/0.480
3el51UNGag-Pol polyprotein/0.480
3i2l2NCProtease/0.480
3nyg2NCGag-Pol polyprotein3.4.23.160.480
3sa5A69Protease/0.480
3sa9A68Protease/0.480
3uhl2NCGag-Pol polyprotein3.4.23.160.480
4a4qUX9Pol protein/0.480
1a9mU0EGag-Pol polyprotein/0.479
1hsgMK1Gag-Pol polyprotein/0.479
2qi5MZ7Gag-Pol polyprotein/0.479
2rkfAB1Pol protein/0.479
3djkG55Gag-Pol polyprotein3.4.23.160.479
1d4sTPVGag-Pol polyprotein3.4.23.160.478
1ec0BEDGag-Pol polyprotein3.4.23.160.478
1vijBAYGag-Pol polyprotein/0.478
2f80017Gag-Pol polyprotein3.4.23.160.478
3oxcROCProtease/0.478
4djoMK5Pol polyprotein/0.478
1idb0DOGag-Pol polyprotein/0.477
1yt9OISGag-Pol polyprotein/0.477
2fde385Gag-Pol polyprotein3.4.23.160.477
3ggaGGWGag-Pol polyprotein/0.477
1g35AHFGag-Pol polyprotein3.4.23.160.476
1hiv1ZKGag-Pol polyprotein/0.476
1hvlA76Gag-Pol polyprotein/0.476
1hxwRITGag-Pol polyprotein/0.476
1k1u0Q4Gag-Pol polyprotein3.4.23.160.476
1rl8RITGag-Pol polyprotein3.4.23.160.476
2fxeDR7Gag-Pol polyprotein3.4.23.160.476
3kfn3TLGag-Pol polyprotein/0.476
4a6bQG8Gag-Pol polyprotein3.4.23.160.476
2wkz5AHGag-Pol polyprotein/0.475
3gi6D78Gag-Pol polyprotein/0.475
3pwrROCGag-Pol polyprotein3.4.23.160.475
3zpuM8BGag-Pol polyprotein3.4.23.160.475
4j55031Gag-Pol polyprotein3.4.23.160.475
4j5j478Gag-Pol polyprotein3.4.23.160.475
1ebwBEIGag-Pol polyprotein3.4.23.160.474
3em6017Gag-Pol polyprotein3.4.23.160.474
1fej2NCGag-Pol polyprotein3.4.23.160.472
1hvkA79Gag-Pol polyprotein/0.472
1t7kBH0Gag-Pol polyprotein3.4.23.160.472
2cen4AHProtease/0.472
2f81017Gag-Pol polyprotein3.4.23.160.472
2upjU02Gag-Pol polyprotein3.4.23.160.472
2xyeCXGGag-Pol polyprotein/0.472
3slz3TLPutative gag-pro-pol polyprotein/0.472
1bai0Q4Gag-Pro polyprotein/0.471
1d4iBEGGag-Pol polyprotein3.4.23.160.471
1fg62NCGag-Pol polyprotein3.4.23.160.471
3d1xROCGag-Pol polyprotein3.4.23.160.471
3kddJZQGag-Pol polyprotein3.4.23.160.471
3nxe2NCProtease/0.471
4a6cQG9Gag-Pol polyprotein3.4.23.160.471
4djpM73Pol polyprotein/0.471
1hosPHPGag-Pol polyprotein/0.470
2avm2NCGag-Pol polyprotein3.4.23.160.470
2idw017Protease/0.470
2p3a3TLPol protein/0.470
2q5kAB1Protease/0.470
3cyxROCGag-Pol polyprotein3.4.23.160.470
3dcrKVSProtease/0.470
3k4vROCGag-Pol polyprotein3.4.23.160.470
3qaaG04Gag-Pol polyprotein3.4.23.160.470
3st5G89Gag-Pol polyprotein3.4.23.160.470
1n49RITGag-Pol polyprotein3.4.23.160.469
1odw0E8Gag-Pol polyprotein3.4.23.160.469
2hc0AB2Protease/0.469
3jvy017Gag-Pol polyprotein3.4.23.160.469
3nls016Gag-Pol polyprotein3.4.23.160.469
4qgiROCGag-Pol polyprotein3.4.23.160.469
1bwaXV6Gag-Pol polyprotein3.4.23.160.468
1fgc2NCGag-Pol polyprotein3.4.23.160.468
1iiq0ZRGag-Pol polyprotein3.4.23.160.468
2f8g017Gag-Pol polyprotein3.4.23.160.468
2ien017Gag-Pol polyprotein3.4.23.160.468
1hxbROCGag-Pol polyprotein3.4.23.160.467
1t7i017Gag-Pol polyprotein3.4.23.160.467
2bb9AKCGag-Pol polyprotein3.4.23.160.467
2hs2017Protease/0.467
2pqzG0GGag-Pol polyprotein3.4.23.160.467
2wl05AHGag-Pol polyprotein/0.467
3cyw017Gag-Pol polyprotein3.4.23.160.467
3mxeK54Gag-Pol polyprotein3.4.23.160.467
4njsG08Protease/0.467
1d4kPI8Gag-Pol polyprotein3.4.23.160.466
3ekyDR7Gag-Pol polyprotein3.4.23.160.466
3sa4F72Protease/0.466
1jld0PPGag-Pol polyprotein/0.465
2qi7MZ9Gag-Pol polyprotein/0.465
2qnqQN3Gag-Pol polyprotein3.4.23.160.465
3bgcLJHGag-Pol polyprotein3.4.23.160.465
3em3478Gag-Pol polyprotein3.4.23.160.465
1ec1BEEGag-Pol polyprotein3.4.23.160.464
2hb3GRLProtease/0.464
3sabF78Protease/0.464
4k4p3TLGag-Pol polyprotein/0.464
1tcxIM1Gag-Pol polyprotein3.4.23.160.463
1zsf0ZSGag-Pol polyprotein3.4.23.160.463
2r5q1UNGag-Pol polyprotein/0.463
3jvwDMPGag-Pol polyprotein3.4.23.160.463
3oxv478Gag-Pol polyprotein3.4.23.160.463
3sa6F71Protease/0.463
3saa77FProtease/0.463
1c6zROCProtease/0.462
1daz0Q4Gag-Pol polyprotein3.4.23.160.462
1ebyBEBGag-Pol polyprotein3.4.23.160.462
1ff02NCGag-Pol polyprotein3.4.23.160.462
1fg80Q4Gag-Pol polyprotein3.4.23.160.462
1msmJE2Gag-Pol polyprotein3.4.23.160.462
1sdtMK1Gag-Pol polyprotein3.4.23.160.462
1d4jMSCGag-Pol polyprotein3.4.23.160.461
1ebzBECGag-Pol polyprotein3.4.23.160.461
1meuDMPGag-Pol polyprotein3.4.23.160.461
1ohr1UNV-1 PROTEASE protein/0.461
3bvb017Gag-Pol polyprotein3.4.23.160.461
3vf7031Gag-Pol polyprotein3.4.23.160.461
1hviA77Protease/0.460
1iziQ50Gag-Pol polyprotein3.4.23.160.460
2qhyMZ1Gag-Pol polyprotein/0.460
3el9DR7Gag-Pol polyprotein3.4.23.160.460
3kfs3TLGag-Pol polyprotein/0.460
3oxw017Gag-Pol polyprotein3.4.23.160.460
3t3c017Gag-Pol polyprotein3.4.23.160.460
1bv7XV6Gag-Pol polyprotein3.4.23.160.459
1dw60Q4Gag-Pol polyprotein3.4.23.160.459
1mtrPI6Gag-Pol polyprotein3.4.23.160.459
1sguMK1Gag-Pol polyprotein3.4.23.160.459
2b7zMK1Gag-Pol polyprotein/0.459
2i4vDJRV-1 protease/0.459
2pyn1UNGag-Pol polyprotein3.4.23.160.459
2r38G4GGag-Pol polyprotein3.4.23.160.459
2r43G3GGag-Pol polyprotein3.4.23.160.459
2z54AB1Gag-Pol polyprotein3.4.23.160.459
3bva2NCGag-Pol polyprotein3.4.23.160.459
3el4ROCGag-Pol polyprotein3.4.23.160.458
3s56ROCProtease/0.458
3sacAF8Protease/0.458
2i4uDJRProtease/0.457
2qci065Gag-Pol polyprotein3.4.23.160.457
2qnpQN2Gag-Pol polyprotein3.4.23.160.457
3ekv478Gag-Pol polyprotein3.4.23.160.457
3nuo478Gag-Pol polyprotein3.4.23.160.457
4dfg0JVGag-Pol polyprotein3.4.23.160.457
4njt017Protease/0.457
1t3r017Gag-Pol polyprotein3.4.23.160.456
3el1DR7Gag-Pol polyprotein3.4.23.160.456
3fx5KNIGag-Pol polyprotein3.4.23.160.456
3qbfJHGGag-Pol polyprotein3.4.23.160.456
7upjINUGag-Pol polyprotein3.4.23.160.456
1hpxKNIGag-Pol polyprotein/0.455
2q641UNGag-Pol polyprotein3.4.23.160.455
2qak1UNGag-Pol polyprotein3.4.23.160.455
2r5pMK1Gag-Pol polyprotein/0.455
2z4o065Gag-Pol polyprotein3.4.23.160.455
3nu6478Gag-Pol polyprotein3.4.23.160.455
1b6kPI5Gag-Pol polyprotein3.4.23.160.454
1d4hBEHGag-Pol polyprotein3.4.23.160.454
1ida0POGag-Pol polyprotein3.4.23.470.454
1qbu846Gag-Pol polyprotein3.4.23.160.454
1sbgIM1Gag-Pol polyprotein/0.454
2avvMK1Gag-Pol polyprotein3.4.23.160.454
2p3c3TLProtease/0.454
2q54MU1Protease/0.454
3nu5478Gag-Pol polyprotein3.4.23.160.454
3nwxKVSGag-Pol polyprotein3.4.23.160.454
3o9cK20Pol polyprotein/0.454
3oy4017Gag-Pol polyprotein3.4.23.160.454
4dqc017Gag-Pol polyprotein/0.454
4dqf017Gag-Pol polyprotein/0.454
1ajvNMBGag-Pol polyprotein3.4.23.160.453
1d4lPI9Gag-Pol polyprotein3.4.23.160.453
1kzkJE2Gag-Pol polyprotein3.4.23.160.453
1muiAB1Protease/0.453
2cej1AHPol protein/0.453
3o9bK2APol polyprotein/0.453
3pwm017Gag-Pol polyprotein3.4.23.160.453
3qn8NI7Gag-Pol polyprotein3.4.23.160.453
1qbrXV6Gag-Pol polyprotein3.4.23.160.452
1sduMK1Gag-Pol polyprotein3.4.23.160.452
2pym1UNGag-Pol polyprotein3.4.23.160.452
3o9gF53Gag-Pol polyprotein/0.452
3s43478Protease/0.452
1bdrIM1Gag-Pol polyprotein3.4.23.160.451
1hvrXK2Gag-Pol polyprotein/0.451
1npvL27Gag-Pol polyprotein3.4.23.160.451
2i4dQFIProtease/0.451
3gi4K60Gag-Pol polyprotein/0.451
3nu4478Gag-Pol polyprotein3.4.23.160.451
3o9fK2DGag-Pol polyprotein/0.451
1hihC20Gag-Pol polyprotein/0.450
1hpoUNIGag-Pol polyprotein3.4.23.160.450
1npa3NHGag-Pol polyprotein3.4.23.160.450
1npwLGZGag-Pol polyprotein3.4.23.160.450
2bbbHH1Gag-Pol polyprotein3.4.23.160.450
3aidARQGag-Pol polyprotein3.4.23.160.450
3mws017Pol protein/0.450
4njuTPVProtease/0.450
1b6mPI6Gag-Pol polyprotein3.4.23.160.449
1z1hHBBGag-Pol polyprotein3.4.23.160.449
2qd7065Gag-Pol polyprotein3.4.23.160.449
4dqe017Gag-Pol polyprotein/0.449
4i8zG08Gag-Pol polyprotein3.4.23.160.449
1a8k0Q4Gag-Pol polyprotein3.4.23.160.448
1b6pPI7Gag-Pol polyprotein3.4.23.160.448
1ebk0Q4Gag-Pol polyprotein3.4.23.160.448
1odyLP1Gag-Pol polyprotein3.4.23.160.448
1sh9RITGag-Pol polyprotein3.4.23.160.448
2qhzMZ2Gag-Pol polyprotein/0.448
2qi6MZ8Gag-Pol polyprotein/0.448
3lzu017Gag-Pol polyprotein3.4.23.160.448
3qp0NI8Gag-Pol polyprotein3.4.23.160.448
3qrmNK7Gag-Pol polyprotein3.4.23.160.448
1mesDMPGag-Pol polyprotein3.4.23.160.447
4q1y017Gag-Pol polyprotein3.4.23.160.447
3o9hK2EGag-Pol polyprotein/0.446
3o9iA61Gag-Pol polyprotein/0.446
1a8g2Z4Gag-Pol polyprotein3.4.23.160.445
1a940Q4Gag-Pol polyprotein3.4.23.160.445
1ajxAH1Gag-Pol polyprotein3.4.23.160.445
1c6x3INProtease/0.445
1c70L75Protease/0.445
1izhQ50Protease/0.445
2hs1017Protease/0.445
3ekx1UNGag-Pol polyprotein3.4.23.160.445
3i6oGR6Gag-Pol polyprotein3.4.23.160.445
3qrsNK8Gag-Pol polyprotein3.4.23.160.445
1g2kNM1Gag-Pol polyprotein3.4.23.160.444
1mrwK57Gag-Pol polyprotein3.4.23.160.444
1z1rHBHGag-Pol polyprotein3.4.23.160.444
2avsMK1Gag-Pol polyprotein3.4.23.160.444
2r3tG4GGag-Pol polyprotein3.4.23.160.444
3tog079Gag-Pol polyprotein2.7.7.490.444
9hvp0E9Gag-Pol polyprotein/0.444
1c6yMK1Protease/0.443
1msnJE2Gag-Pol polyprotein3.4.23.160.443
3dckKVIProtease/0.443
1qbsDMPGag-Pol polyprotein3.4.23.160.442
2fleAIProtease/0.442
2qi4MZ6Gag-Pol polyprotein/0.442
3sa8K83Protease/0.442
2b60RITPol polyprotein/0.441
2nnpROCProtease/0.441
3o9eA60Pol polyprotein/0.441
1hiiC20Gag-Pol polyprotein/0.440
3el01UNGag-Pol polyprotein3.4.23.160.440
3ggu017Gag-Pol polyprotein3.4.23.160.440
3sm2478Putative gag-pro-pol polyprotein/0.440
3ufnROCGag-Pol polyprotein/0.440