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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3ldgSAHUncharacterized protein

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3ldgSAHUncharacterized protein/1.000
1mhtSAHModification methylase HhaI2.1.1.370.508
5mhtSAHModification methylase HhaI2.1.1.370.498
7mhtSAHModification methylase HhaI2.1.1.370.492
1fjxSAHModification methylase HhaI2.1.1.370.485
2i9kSAHModification methylase HhaI2.1.1.370.483
3tm5SFGUncharacterized protein/0.482
2hmySAMModification methylase HhaI2.1.1.370.480
8mhtSAHModification methylase HhaI2.1.1.370.478
9mhtSAHModification methylase HhaI2.1.1.370.475
3tljSAHUncharacterized protein/0.471
1skmSAHModification methylase HhaI2.1.1.370.467
3tm4SAMUncharacterized protein/0.466
10mhSAHModification methylase HhaI2.1.1.370.465
4mhtSAHModification methylase HhaI2.1.1.370.461
2zcjSAHModification methylase HhaI2.1.1.370.458
5e8jSAHmRNA cap guanine-N7 methyltransferase2.1.1.560.457
2uyhSAHModification methylase HhaI2.1.1.370.456
3mhtSAHModification methylase HhaI2.1.1.370.451
3pt6SAHDNA (cytosine-5)-methyltransferase 12.1.1.370.451
2c7qSAHModification methylase HhaI2.1.1.370.450
3zkpERBErythromycin C-12 hydroxylase1.14.13.1540.449
5f8eSAHPossible transcriptional regulatory protein/0.448
3g7jGTXGlutathione transferase GST1-4/0.446
4jx1CAMCamphor 5-monooxygenase1.14.15.10.446
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.443