sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3kz1 | GSP | Transforming protein RhoA |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3kz1 | GSP | Transforming protein RhoA | / | 1.000 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.552 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.540 | |
| 4mit | GTP | Rho-related protein racC | / | 0.540 | |
| 5hpy | GDP | Transforming protein RhoA | / | 0.537 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.531 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.530 | |
| 1a2b | GSP | Transforming protein RhoA | / | 0.528 | |
| 4xoi | GTP | Transforming protein RhoA | / | 0.527 | |
| 1m7b | GTP | Rho-related GTP-binding protein RhoE | / | 0.522 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.522 | |
| 2fju | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.522 | |
| 4gzm | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.522 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.513 | |
| 3sbd | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.509 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.508 | |
| 1s1c | GNP | Transforming protein RhoA | / | 0.508 | |
| 2w2x | GSP | Ras-related C3 botulinum toxin substrate 2 | / | 0.507 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.505 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.504 | |
| 2qme | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.501 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.501 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.500 | |
| 3ddc | GNP | GTPase HRas | / | 0.498 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.496 | |
| 3th5 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.492 | |
| 4js0 | GNP | Cell division control protein 42 homolog | / | 0.491 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.490 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.489 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.488 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.487 | |
| 1z2c | GNP | Rho-related GTP-binding protein RhoC | / | 0.481 | |
| 2x19 | GTP | GTP-binding nuclear protein GSP1/CNR1 | / | 0.481 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.480 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.479 | |
| 4nyi | GNP | GTPase HRas | / | 0.476 | |
| 3sbe | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.475 | |
| 4nyj | GNP | GTPase HRas | / | 0.475 | |
| 4k81 | GTP | GTPase HRas | / | 0.473 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.472 | |
| 3i3s | GNP | GTPase HRas | / | 0.472 | |
| 1gwn | GTP | Rho-related GTP-binding protein RhoE | / | 0.469 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.469 | |
| 4ol0 | GTP | GTP-binding nuclear protein Ran | / | 0.468 | |
| 2zet | GTP | Ras-related protein Rab-27B | / | 0.466 | |
| 1cs4 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.464 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.464 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.462 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.462 | |
| 3kuc | GDP | Ras-related protein Rap-1A | / | 0.462 | |
| 3law | GNP | Ras-related protein Rab-7a | / | 0.459 | |
| 1ibr | GNP | GTP-binding nuclear protein Ran | / | 0.458 | |
| 1ow3 | GDP | Transforming protein RhoA | / | 0.457 | |
| 1z0a | GDP | Ras-related protein Rab-2A | / | 0.457 | |
| 3lbn | GNP | GTPase HRas | / | 0.456 | |
| 3tnf | GNP | Ras-related protein Rab-8A | / | 0.456 | |
| 2cls | GTP | Rho-related GTP-binding protein Rho6 | / | 0.455 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.453 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.453 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.450 | |
| 3oiu | GNP | GTPase HRas | / | 0.449 | |
| 2bku | GTP | GTP-binding nuclear protein Ran | / | 0.448 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.447 | |
| 3tkl | GTP | Ras-related protein Rab-1A | / | 0.447 | |
| 4dlt | GNP | GTPase HRas | / | 0.447 | |
| 2rge | GNP | GTPase HRas | / | 0.446 | |
| 3oiv | GNP | GTPase HRas | / | 0.446 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.445 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.444 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.443 | |
| 3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.443 | |
| 4xvr | GNP | GTPase HRas | / | 0.441 | |
| 1oix | GDP | Ras-related protein Rab-11A | / | 0.440 | |
| 3kko | GNP | Ras-related protein M-Ras | / | 0.440 |