Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3kt3TYMTryptophan--tRNA ligase, cytoplasmic6.1.1.2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3kt3TYMTryptophan--tRNA ligase, cytoplasmic6.1.1.21.000
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.575
1r6tTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.562
2qujTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.546
3jxeTYMTryptophan--tRNA ligase/0.535
4j75TYMTryptophan--tRNA ligase/0.520
3zxiTYATyrosine--tRNA ligase, mitochondrial6.1.1.10.481
1vbmYSATyrosine--tRNA ligase6.1.1.10.474
2pidYSATyrosine--tRNA ligase, mitochondrial6.1.1.10.466
2yy5WSATryptophan--tRNA ligase6.1.1.20.465
4wsoNADProbable nicotinate-nucleotide adenylyltransferase/0.457
1n1dC2GGlycerol-3-phosphate cytidylyltransferase2.7.7.390.447