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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3ko5ADPD-tyrosyl-tRNA(Tyr) deacylase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3ko5ADPD-tyrosyl-tRNA(Tyr) deacylase/1.000
4nbjD3YD-tyrosyl-tRNA(Tyr) deacylase/0.608
3ko3ADPD-tyrosyl-tRNA(Tyr) deacylase/0.594
4nbiD3YD-tyrosyl-tRNA(Tyr) deacylase/0.555
3lakKR1Gag-Pol polyprotein2.7.7.490.500
1dgbNDPCatalase1.11.1.60.499
1jdzFMBPurine nucleoside phosphorylase/0.497
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.496
3gcq1BUMitogen-activated protein kinase 14/0.496
2jc6QPPCalcium/calmodulin-dependent protein kinase type 1D2.7.11.170.495
3arvSAUChitinase A/0.494
1yryMSGPurine nucleoside phosphorylase2.4.2.10.493
1xngDNDNH(3)-dependent NAD(+) synthetase6.3.1.50.492
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.491
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.490
1dghNDPCatalase1.11.1.60.488
2c1zKMPAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.488
4to5DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.488
1fvpFMANon-fluorescent flavoprotein/0.487
2bakAQZMitogen-activated protein kinase 14/0.487
4a9yAQZMitogen-activated protein kinase 14/0.487
4jhiEMUNodulin-13/0.487
8catNDPCatalase1.11.1.60.486
1uwhBAXSerine/threonine-protein kinase B-raf2.7.11.10.485
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.484
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.484
2aouCQAHistamine N-methyltransferase2.1.1.80.484
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.484
4bfxZVXPantothenate kinase2.7.1.330.484
3h4vDVPPteridine reductase 11.5.1.330.483
2lbaCHOFatty acid binding protein 6/0.482
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.482
4to2DGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.482
3znqSS8D-amino-acid oxidase1.4.3.30.481
1e92HBIPteridine reductase 11.5.1.330.480
2d06ESTSulfotransferase 1A12.8.2.10.480
3d4bDZDNAD-dependent protein deacetylase/0.480
1dgfNDPCatalase1.11.1.60.478
1obnASVIsopenicillin N synthase1.21.3.10.478
1p33MTXPteridine reductase 11.5.1.330.478
2fzdTOLAldose reductase1.1.1.210.478
3b9oFMNAlkane monoxygenase/0.478
1thnADPAnti-sigma F factor/0.477
1k4gAIQQueuine tRNA-ribosyltransferase2.4.2.290.476
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.476
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.476
1rgsCMPcAMP-dependent protein kinase type I-alpha regulatory subunit/0.475
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.475
3v94WYQPhosphodiesterase/0.475
4at4T6EBDNF/NT-3 growth factors receptor2.7.10.10.475
1c7oPPGHemolysin/0.474
1rszDIHPurine nucleoside phosphorylase2.4.2.10.474
1yhoTRRDihydrofolate reductase1.5.1.30.474
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.474
3zc3FADFerredoxin--NADP reductase1.18.1.20.474
4iyg1HUStrictosidine synthase4.3.3.20.473
1bx0FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.472
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.472
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.472
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.471
2ekpNAD2-deoxy-D-gluconate 3-dehydrogenase/0.470
2yhuWHFPteridine reductase/0.470
4a4l939Serine/threonine-protein kinase PLK12.7.11.210.470
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.470
4uugPXGBranched-chain amino acid aminotransferase, putative/0.470
1klmSPPGag-Pol polyprotein2.7.7.490.469
2mm3CHOGastrotropin/0.469
3lfeZ84Mitogen-activated protein kinase 14/0.469
3s7bNH5N-lysine methyltransferase SMYD2/0.469
4n4t2GVTankyrase-12.4.2.300.469
4tjy3GNTankyrase-22.4.2.300.469
5ahkFADAcetolactate synthase II, large subunit/0.469
1frbZSTAldose reductase-related protein 2/0.468
1pr6XYAPurine nucleoside phosphorylase DeoD-type/0.468
1u0wSTLChalcone synthase 22.3.1.740.468
4feu537Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.468
4g2wNI0cGMP-specific 3',5'-cyclic phosphodiesterase/0.468
1afsTES3-alpha-hydroxysteroid dehydrogenase1.1.1.500.467
2cleF6FTryptophan synthase alpha chain/0.467
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.467
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.467
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.467
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.467
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.467
4da6GA2Purine nucleoside phosphorylase DeoD-type2.4.2.10.467
4y1bNAPAntE/0.467
1blzACVIsopenicillin N synthase1.21.3.10.466
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.466
3q3cNADNAD-dependent L-serine dehydrogenase/0.466
4bfpSWYTankyrase-22.4.2.300.466
4hlm16STankyrase-22.4.2.300.466
4rh10TTSpore photoproduct lyase/0.466
3dgeADPSensor histidine kinase/0.465
3hbfMYCFlavonoid 3-O-glucosyltransferase2.4.10.465
3n39FMNProtein NrdI/0.465
3nlpH4BNitric oxide synthase, brain1.14.13.390.465
4c73TLH3-oxoacyl-ACP synthase/0.465
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.465
7catNDPCatalase1.11.1.60.465
1p8dCO1Oxysterols receptor LXR-beta/0.464
1zdwFLVPrenyltransferase/0.464
2jizANPATP synthase subunit beta, mitochondrial3.6.3.140.464
3fp0FP015-O-acetyltransferase/0.464
3fsjD7KBenzoylformate decarboxylase4.1.1.70.464
3pqbVGPPutative oxidoreductase/0.464
3t3q9PLCytochrome P450 2A61.14.130.464
4mrxCZHObelin/0.464
1dggNDPCatalase1.11.1.60.463
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.463
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.463
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.463
3cr0809Wee1-like protein kinase2.7.10.20.463
3qm4PN0Cytochrome P450 2D6/0.463
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.463
4msg2C6Tankyrase-12.4.2.300.463
1axwMTXThymidylate synthase/0.462
1zx1CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.462
2hdjNDPAldo-keto reductase family 1 member C2/0.462
3aosJH2Hemolymph juvenile hormone binding protein/0.462
4g2yNI5cGMP-specific 3',5'-cyclic phosphodiesterase/0.462
4rrqA3SThreonine--tRNA ligase6.1.1.30.462
5ab6CAANonspecific lipid-transfer protein, putative/0.462
5iu4ZMAAdenosine receptor A2a/0.462
1l0oADPAnti-sigma F factor/0.461
1nceCB3Thymidylate synthase/0.461
1w06W05Isopenicillin N synthase1.21.3.10.461
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.461
2vqoTFGHistone deacetylase 43.5.1.980.461
3aezGDPPantothenate kinase2.7.1.330.461
3g58988cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
3l3rOAGDihydrofolate reductase1.5.1.30.461
4c6zTLE3-oxoacyl-ACP synthase/0.461
4c717RD3-oxoacyl-ACP synthase/0.461
4dyp0MSNucleoprotein/0.461
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
4jq3ZOMAldo-keto reductase family 1 member C2/0.461
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.461
4z87GDPInosine-5'-monophosphate dehydrogenase/0.461
1yciNDFHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.460
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.460
2gvcFADThiol-specific monooxygenase1.14.130.460
2hxzH7JCathepsin S3.4.22.270.460
2v5aLZLBiotin carboxylase6.3.4.140.460
2vt4P32Beta-1 adrenergic receptor/0.460
3gwfNAPCyclohexanone monooxygenase/0.460
3sl8JN7cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.460
4af7FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.460
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
4e2yJHZMethyltransferase/0.460
4i9z5BAcGMP-specific 3',5'-cyclic phosphodiesterase/0.460
1kceCB3Thymidylate synthase/0.459
1vyw292Cyclin-dependent kinase 22.7.11.220.459
1wp4NDP3-hydroxyisobutyrate dehydrogenase/0.459
2bjsACVIsopenicillin N synthase1.21.3.10.459
2y71CB63-dehydroquinate dehydratase4.2.1.100.459
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.459
3fpkFADFerredoxin-NADP reductase/0.459
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
4f0rMTA5-methylthioadenosine/S-adenosylhomocysteine deaminase/0.459
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.459
5irnADPNucleotide binding oligomerization domain containing 2/0.459
1dnaCB3Thymidylate synthase/0.458
1mczRMNBenzoylformate decarboxylase4.1.1.70.458
2ejzSAHDiphthine synthase/0.458
2vz0D64Pteridine reductase/0.458
3a25SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase/0.458
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.458
3uayADNPurine nucleoside phosphorylase DeoD-type/0.458
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.458
4phlPILPhosphodiesterase/0.458
1e2nRCAThymidine kinase/0.457
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.457
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.457
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3jpuTY4Transcriptional activator protein LasR/0.457
4fweFADLysine-specific histone demethylase 1B10.457
4qfyDCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.457
4wctFADFructosyl amine:oxygen oxidoreductase/0.457
5cflC2EStimulator of interferon genes protein/0.457
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.456
1gpnHUBAcetylcholinesterase3.1.1.70.456
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.456
1mvtDTMDihydrofolate reductase1.5.1.30.456
1u1d181Uridine phosphorylase2.4.2.30.456
2a9y26AAdenosine kinase2.7.1.200.456
2b01TUDPhospholipase A2, major isoenzyme3.1.1.40.456
2vuuNAPNitrogen metabolite repression protein nmrA/0.456
3h3r14HCollagen type IV alpha-3-binding protein/0.456
3jsuKA5Bifunctional dihydrofolate reductase-thymidylate synthase/0.456
3jx5H4BNitric oxide synthase, brain1.14.13.390.456
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.456
3tdaPN0Cytochrome P450 2D6/0.456
4b2gV1NUncharacterized protein/0.456
5cc9DDFDihydrofolate reductase1.5.1.30.456
1a80NDP2,5-diketo-D-gluconic acid reductase A1.1.1.3460.455
1j3jCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.455
1nzyBCA4-chlorobenzoyl coenzyme A dehalogenase3.8.1.70.455
1ye6NAPNAD(P)H-dependent D-xylose reductase1.1.1.3070.455
2dvlFADAcyl-CoA dehydrogenase/0.455
2io6330Wee1-like protein kinase2.7.10.20.455
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.455
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.455
3uyk0CXProbable NDP-rhamnosyltransferase/0.455
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.455
4a81DXCMajor pollen allergen Bet v 1-A/0.455
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.455
4e32DWNMethyltransferase/0.455
4g090VDHistidinol dehydrogenase/0.455
4jauADPSensor histidine kinase/0.455
4jlj1NMDeoxycytidine kinase2.7.1.740.455
4qa0SHHHistone deacetylase 83.5.1.980.455
3pblETQD(3) dopamine receptor/0.455
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.454
2in6839Wee1-like protein kinase2.7.10.20.454
2pdlTOLAldose reductase1.1.1.210.454
2r7nADP5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase/0.454
3djlFADPutative acyl-CoA dehydrogenase AidB1.3.990.454
3ha5SFGHydroxymycolate synthase MmaA42.1.10.454
3nosH4BNitric oxide synthase, endothelial1.14.13.390.454
3rkuNAPNADP-dependent 3-hydroxy acid dehydrogenase/0.454
4bqg50QHeat shock protein HSP 90-alpha/0.454
4g95OAGDihydrofolate reductase1.5.1.30.454
4jlm1NNDeoxycytidine kinase2.7.1.740.454
4jsgH4BNitric oxide synthase, brain1.14.13.390.454
4orkGDPBifunctional AAC/APH2.3.10.454
4ldeP0GBeta-2 adrenergic receptor/0.454
1clqGDPDNA-directed DNA polymerase/0.453
1dhfFOLDihydrofolate reductase1.5.1.30.453
1h36R88Squalene--hopene cyclase4.2.1.1290.453
1hk3T44Serum albumin/0.453
1hqtNAPAlcohol dehydrogenase [NADP(+)]1.1.1.20.453
1o6rR19Squalene--hopene cyclase4.2.1.1290.453
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.453
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.453
2bfaCB3Pteridine reductase 11.5.1.330.453
2vq3NAPMetalloreductase STEAP3/0.453
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.453
3gsiTHGDimethylglycine oxidase1.5.3.100.453
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.453
3nlqH4BNitric oxide synthase, brain1.14.13.390.453
4gtt7TQGeranylgeranyl transferase type-2 subunit beta2.5.1.600.453
4iomFOLFormate--tetrahydrofolate ligase/0.453
4o1mNADEnoyl-acyl carrier reductase/0.453
4to4DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.453
1k8zIAGTryptophan synthase alpha chain/0.452
1s3uTQDDihydrofolate reductase1.5.1.30.452
2bsxNOSPurine nucleoside phosphorylase/0.452
2g7yMO9Cathepsin S3.4.22.270.452
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.452
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3n33AESBeta-peptidyl aminopeptidase BapA/0.452
3owuEQUSteroid Delta-isomerase5.3.3.10.452
3um81CYBifunctional dihydrofolate reductase-thymidylate synthase/0.452
3wo0ADPAlanine--anticapsin ligase/0.452
4dvi2IWTankyrase-12.4.2.300.452
4rrhA3SProbable threonine--tRNA ligase 26.1.1.30.452
1bk0ACVIsopenicillin N synthase1.21.3.10.451
2tohHBITyrosine 3-monooxygenase1.14.16.20.451
2xvfFADPutative flavin-containing monooxygenase/0.451
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3d73NBBPheromone-binding protein ASP1/0.451
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3eblGA4Gibberellin receptor GID1/0.451
3fu83DMLaccase-11.10.3.20.451
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.451
3nu03TUDihydrofolate reductase1.5.1.30.451
4bb3KKAIsopenicillin N synthase1.21.3.10.451
4bv9NDPKetimine reductase mu-crystallin1.5.1.250.451
4dbs0HVAldo-keto reductase family 1 member C3/0.451
4h7zGUNQueuine tRNA-ribosyltransferase2.4.2.290.451
4p9dTMPDeoxycytidylate deaminase/0.451
4yal2AMNADPH--cytochrome P450 reductase/0.451
4ybnFADFlavin-nucleotide-binding protein/0.451
1kzjCB3Thymidylate synthase/0.450
1lkdBP6Biphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.450
1ry0PG2Aldo-keto reductase family 1 member C3/0.450
2jav5Z5Serine/threonine-protein kinase Nek22.7.11.10.450
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
4arbC57Acetylcholinesterase3.1.1.70.450
4cdmFO1Deoxyribodipyrimidine photolyase/0.450
4fam0SZAldo-keto reductase family 1 member C3/0.450
4kfbT27Gag-Pol polyprotein2.7.7.490.450
4xoqF42Coenzyme F420:L-glutamate ligase/0.450
5efwFMNNPH1-1/0.450
1gjrFADFerredoxin--NADP reductase1.18.1.20.449
1luqBTNStreptavidin/0.449
1odnAPVIsopenicillin N synthase1.21.3.10.449
1qk35GPHypoxanthine-guanine-xanthine phosphoribosyltransferase2.4.2.220.449
1ro98BRcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.449
1swgBTNStreptavidin/0.449
2bu9HFVIsopenicillin N synthase1.21.3.10.449
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.449
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.449
2v2qNVG4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.449
2wowNDPTrypanothione reductase/0.449
3bi6396Wee1-like protein kinase2.7.10.20.449
3ftxRE2Leukotriene A-4 hydrolase3.3.2.60.449
3gb4D3MDdmC/0.449
3ihgVAKAklavinone 12-hydroxylase RdmE/0.449
3nxyD2HDihydrofolate reductase1.5.1.30.449
3q7jFBOTricorn protease-interacting factor F33.4.110.449
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.449
4bcsBTNAvidin-related protein 4/5/0.449
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.449
4i8vBHFCytochrome P450 1A11.14.14.10.449
4kxjP34Nucleoprotein/0.449
4li61XOTankyrase-12.4.2.300.449
4qg0DUTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.449
4rr6A3SProbable threonine--tRNA ligase 26.1.1.30.449
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.449
1fncFDAFerredoxin--NADP reductase, chloroplastic1.18.1.20.448
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.448
1t13INI6,7-dimethyl-8-ribityllumazine synthase 2/0.448
1tilATPAnti-sigma F factor/0.448
1xp9AIJEstrogen receptor/0.448
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.448
2hw2RFPRifampin ADP-ribosyl transferase/0.448
3dlgGWEGag-Pol polyprotein2.7.7.490.448
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3pz3PZ3Geranylgeranyl transferase type-2 subunit beta2.5.1.600.448
3zkyWT4Isopenicillin N synthase1.21.3.10.448
4hy6FJ1Heat shock protein HSP 90-alpha/0.448
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.448
4kak06UDihydrofolate reductase1.5.1.30.448
1lgtBP3Biphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.447
1oj4CDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.447
1umlFR4Adenosine deaminase3.5.4.40.447
1x8lOXRRetinol dehydratase/0.447
1xpcAITEstrogen receptor/0.447
1ygjRMCPyridoxal kinase2.7.1.350.447
1zg32HIIsoflavone 4'-O-methyltransferase/0.447
2dhfDZFDihydrofolate reductase1.5.1.30.447
2pdh47DAldose reductase1.1.1.210.447
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
3jq8DX3Pteridine reductase, putative/0.447
3nwlNDPCatalase1.11.1.60.447
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.447
3wavDWVEctonucleotide pyrophosphatase/phosphodiesterase family member 23.1.4.390.447
4bdrKAIGlutamate receptor ionotropic, kainate 2/0.447
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.447
4omaLCSMethionine gamma-lyase/0.447
4pnrG18Tankyrase-22.4.2.300.447
5iqiGNPBifunctional AAC/APH2.3.10.447
1b2rFADFerredoxin--NADP reductase1.18.1.20.446
1drfFOLDihydrofolate reductase1.5.1.30.446
1e66HUXAcetylcholinesterase3.1.1.70.446
1jdvADNPurine nucleoside phosphorylase/0.446
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.446
1qv0CZHObelin/0.446
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
2fzjDH3Dihydrofolate reductase1.5.1.30.446
2oaxSNLMineralocorticoid receptor/0.446
3ndjJHZMethyltransferase/0.446
3vo2FADFerredoxin--NADP reductase/0.446
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.446
4hshQEIQueuine tRNA-ribosyltransferase2.4.2.290.446
4y9uNAPNADPH--cytochrome P450 reductase/0.446
1ihiIU5Aldo-keto reductase family 1 member C2/0.445
1pd9CO4Dihydrofolate reductase1.5.1.30.445
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.445
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.445
1uzwCDHIsopenicillin N synthase1.21.3.10.445
1w19T1P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.445
2h21SAMRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic2.1.1.1270.445
3c35KAIGlutamate receptor ionotropic, kainate 1/0.445
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.445
3lkhLT6Genome polyprotein2.7.7.480.445
3rl35GPMetallophosphoesterase MPPED23.10.445
4a3uFMNNADH:flavin oxidoreductase/NADH oxidase/0.445
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.445
5ao1DG3Deoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.445
1bozPRDDihydrofolate reductase1.5.1.30.444
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1gawFADFerredoxin/0.444
1hb3SCVIsopenicillin N synthase1.21.3.10.444
1klkPMDDihydrofolate reductase1.5.1.30.444
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.444
2ovyPFJcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
2rl52RLVascular endothelial growth factor receptor 22.7.10.10.444
2y60M8FIsopenicillin N synthase1.21.3.10.444
3br3ETHTH-type transcriptional regulator QacR/0.444
3hng8STVascular endothelial growth factor receptor 12.7.10.10.444
3hu2AGSTransitional endoplasmic reticulum ATPase3.6.4.60.444
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.444
3q8hAO92-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.444
3siiA1RUncharacterized protein/0.444
3t3r9PLCytochrome P450 2A61.14.130.444
3zbtFADFerredoxin--NADP reductase1.18.1.20.444
4aoaIK2Beta-phenylalanine transaminase2.6.10.444
4fc00T2Serine/threonine-protein kinase B-raf2.7.11.10.444
4hlwTESAndrogen receptor/0.444
4i9qXG4DNA-directed DNA polymerase/0.444
4n1gCEIObelin/0.444
4qx5CMPcGMP-dependent protein kinase 12.7.11.120.444
1el4CTZObelin/0.443
1giqNAIIota toxin component Ia/0.443
1m9hNAD2,5-diketo-D-gluconic acid reductase A1.1.1.3460.443
1xwfADNAdenosylhomocysteinase3.3.1.10.443
1z6tADPApoptotic protease-activating factor 1/0.443
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.443
2fjeFADAdenylylsulfate reductase, subunit A (AprA)/0.443
2lfoGCHFatty acid-binding protein, liver/0.443
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.443
2vrbNAPTriphenylmethane reductase/0.443
2w98P1ZProstaglandin reductase 21.3.1.480.443
2ykvIK2Beta-transaminase/0.443
2zw5COABleomycin acetyltransferase/0.443
3c34KAIGlutamate receptor ionotropic, kainate 1/0.443
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3jq9AX1Pteridine reductase, putative/0.443
3jx4H4BNitric oxide synthase, brain1.14.13.390.443
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.443
4c72TLG3-oxoacyl-ACP synthase/0.443
4du6GTPGTP cyclohydrolase 1/0.443
4g1nNZTPyruvate kinase PKM2.7.1.400.443
4gdpFADPolyamine oxidase FMS1/0.443
4i9i1DYTankyrase-12.4.2.300.443
1ddtAPUDiphtheria toxin/0.442
1wdkACO3-ketoacyl-CoA thiolase/0.442
1x8b824Wee1-like protein kinase2.7.10.20.442
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.442
2ji9ADPOxalyl-CoA decarboxylase4.1.1.80.442
2nq8ZIDEnoyl-ACP reductase/0.442
2vbpVB1Isopenicillin N synthase1.21.3.10.442
2w3wVG9Dihydrofolate reductase/0.442
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
3h3qH13Collagen type IV alpha-3-binding protein/0.442
3lt0FT1Enoyl-ACP reductase/0.442
3mnrSD1Heat shock protein HSP 90-alpha/0.442
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3u8l09QAcetylcholine-binding protein/0.442
4eilFOLBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
4li71XPTankyrase-12.4.2.300.442
4ubtCOASteroid 3-ketoacyl-CoA thiolase/0.442
1ao8MTXDihydrofolate reductase1.5.1.30.441
1l0cCOTSerotonin N-acetyltransferase/0.441
1synF89Thymidylate synthase/0.441
1ye6NADNAD(P)H-dependent D-xylose reductase1.1.1.3070.441
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.441
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.441
2bn4FADNADPH--cytochrome P450 reductase/0.441
2fa3ACOHydroxymethylglutaryl-CoA synthase/0.441
2fjdSFDAdenylylsulfate reductase, subunit A (AprA)/0.441
2mjiKTRFatty acid-binding protein, intestinal/0.441
2qimZEAClass 10 plant pathogenesis-related protein/0.441
2qmyFADRibosyldihydronicotinamide dehydrogenase [quinone]/0.441
2r6jNDPEugenol synthase 11.1.1.3180.441
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.441
2zshGA3Gibberellin receptor GID1A30.441
3biz61EWee1-like protein kinase2.7.10.20.441
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.441
3fznD7KBenzoylformate decarboxylase4.1.1.70.441
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
3lfcZ86Mitogen-activated protein kinase 14/0.441
3lt2FT3Enoyl-ACP reductase/0.441
3rm8RM8Acidic mammalian chitinase3.2.1.140.441
3tg4SAMN-lysine methyltransferase SMYD2/0.441
3vt8YI3Vitamin D3 receptor/0.441
4c43FADFerredoxin--NADP reductase1.18.1.20.441
4eiyZMAAdenosine receptor A2a/0.441
4klrCHDFerrochelatase, mitochondrial4.99.1.10.441
4rrdA3TProbable threonine--tRNA ligase 26.1.1.30.441
1diuBDMDihydrofolate reductase1.5.1.30.440
1e63FADFerredoxin--NADP reductase1.18.1.20.440
1g60SAMModification methylase MboII2.1.1.720.440
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.440
1jtqLY3Thymidylate synthase/0.440
1pq6965Oxysterols receptor LXR-beta/0.440
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.440
1s9dAFBCytohesin-2/0.440
1s9dAFBADP-ribosylation factor 1/0.440
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.440
2clmF6FTryptophan synthase alpha chain/0.440
2ea4F79Methionine aminopeptidase 2/0.440
2g263LGRenin3.4.23.150.440
2obxINI6,7-dimethyl-8-ribityllumazine synthase 22.5.1.780.440
3bi5FADPolyamine oxidase FMS1/0.440
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
3svqH4BNitric oxide synthase, brain1.14.13.390.440
4a83DXCMajor pollen allergen Bet v 1-A/0.440
4g0k0VSGlutathionyl-hydroquinone reductase YqjG1.80.440
4jlk1NODeoxycytidine kinase2.7.1.740.440
4jyzATPGlutamine--tRNA ligase6.1.1.180.440
4n4v2GYTankyrase-12.4.2.300.440
4rnxFMNNADPH dehydrogenase 11.6.99.10.440
4rrgA3TThreonine--tRNA ligase6.1.1.30.440
5dp2NAPCurF/0.440