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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.588
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.572
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.572
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.564
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.542
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.540
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.525
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.519
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.519
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.514
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.492
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.489
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.487
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.483
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.479
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
4gv10XZRAC-alpha serine/threonine-protein kinase2.7.11.10.468
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.462
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
4j95ACPFibroblast growth factor receptor 2/0.460
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.455
3aglA03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.450
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
4iakADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.446
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.445
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
1jklANPDeath-associated protein kinase 12.7.11.10.443
4ii5ADPCyclin-dependent kinase 22.7.11.220.443
1j1bANPGlycogen synthase kinase-3 beta2.7.11.260.441
4ekl0RFRAC-alpha serine/threonine-protein kinase2.7.11.10.441
4iayADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
4iazADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440