sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3keq | NAD | Redox-sensing transcriptional repressor Rex |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3keq | NAD | Redox-sensing transcriptional repressor Rex | / | 1.000 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.506 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.501 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.497 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.493 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.491 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.490 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.488 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.487 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.485 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.483 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.482 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.482 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.481 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.480 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.479 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 2y88 | 2ER | Phosphoribosyl isomerase A | 5.3.1.16 | 0.478 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.477 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.477 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.477 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.477 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.477 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.476 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.475 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.475 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.475 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.475 | |
| 1fml | RTL | Retinol dehydratase | / | 0.472 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.472 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.472 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.472 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.471 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.471 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.471 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.470 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.470 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.469 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.469 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.469 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.469 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.469 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.468 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.468 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.468 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.467 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.467 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.466 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.466 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.465 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.465 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.464 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.464 | |
| 4v0s | 2HN | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.464 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.463 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.463 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.463 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.463 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.463 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.463 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.462 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.462 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.462 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.462 | |
| 1omo | NAD | Alanine dehydrogenase | / | 0.461 | |
| 2jiz | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.461 | |
| 2y05 | RAL | Prostaglandin reductase 1 | / | 0.461 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.461 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.460 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.460 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.460 | |
| 4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.460 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.460 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.459 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.459 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.459 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.459 | |
| 4ixd | 1HV | Integrin alpha-L | / | 0.459 | |
| 5dn1 | AMZ | Phosphoribosyl isomerase A | 5.3.1.16 | 0.459 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.458 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.458 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.458 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.458 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.457 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.457 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.457 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.457 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.456 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.456 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.456 | |
| 2xw7 | NDP | Dihydrofolate reductase | / | 0.456 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.456 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.455 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.455 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.455 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.455 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.455 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.455 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.454 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.454 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4brg | GNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.454 | |
| 1eio | GCH | Gastrotropin | / | 0.453 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.453 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.453 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.453 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.453 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.453 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.453 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.453 | |
| 2qw0 | 34Z | 4-chlorobenzoyl CoA ligase | / | 0.453 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.453 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 4usq | FAD | Pyridine nucleotide-disulfide oxidoreductase | / | 0.453 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.452 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2nr4 | FMN | Conserved protein | / | 0.452 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.452 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.452 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.452 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.452 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.451 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.451 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.451 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.451 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 4brd | ANP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.451 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.451 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.451 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.450 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.450 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.450 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.450 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.450 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.450 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.450 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.450 | |
| 4fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.450 | |
| 4fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.450 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.450 | |
| 1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.449 | |
| 1ja1 | FMN | NADPH--cytochrome P450 reductase | / | 0.449 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.449 | |
| 2acw | UPG | Glycosyltransferase | / | 0.449 | |
| 2ejz | SAH | Diphthine synthase | / | 0.449 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.449 | |
| 2o7o | DXT | Tetracycline repressor protein class D | / | 0.449 | |
| 2yj4 | ATP | Copper-transporting ATPase | / | 0.449 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.449 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.449 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.449 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.449 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.449 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.448 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.448 | |
| 2emu | SAH | Diphthine synthase | / | 0.448 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.448 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.448 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.448 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.448 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 4e2y | JHZ | Methyltransferase | / | 0.448 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.447 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.447 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.447 | |
| 1r2j | FAD | FkbI | / | 0.447 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.447 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.447 | |
| 1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.447 | |
| 1zdw | FLV | Prenyltransferase | / | 0.447 | |
| 2g5c | NAD | Prephenate dehydrogenase | / | 0.447 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.447 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.447 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.447 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.447 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.447 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.447 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.447 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.447 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.446 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.446 | |
| 2get | COK | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.446 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.446 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 2qc8 | ADP | Glutamine synthetase | 6.3.1.2 | 0.446 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.446 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.446 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 3nbv | ANP | Ketohexokinase | / | 0.446 | |
| 3ogw | IMN | Lactoperoxidase | 1.11.1.7 | 0.446 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.446 | |
| 4biw | ANP | Sensor histidine kinase CpxA | / | 0.446 | |
| 4req | 5AD | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.446 | |
| 4u7w | NDP | MxaA | / | 0.446 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.446 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.446 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.445 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.445 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.445 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.445 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.445 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.445 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.445 | |
| 2obx | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | 2.5.1.78 | 0.445 | |
| 2ptf | FMN | Uncharacterized protein MTH_863 | / | 0.445 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.445 | |
| 2xfy | ACX | Beta-amylase | 3.2.1.2 | 0.445 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.445 | |
| 3i58 | 7NA | 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase | / | 0.445 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4eqr | COA | Coenzyme A disulfide reductase | / | 0.445 | |
| 4lk3 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.445 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.445 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.445 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.445 | |
| 5kjc | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 1ayp | INB | Phospholipase A2, membrane associated | / | 0.444 | |
| 1cdo | NAD | Alcohol dehydrogenase 1 | 1.1.1.1 | 0.444 | |
| 1ja0 | FMN | NADPH--cytochrome P450 reductase | / | 0.444 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1t3z | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.444 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.444 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.444 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.444 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.444 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.444 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.444 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.444 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.444 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.444 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.444 | |
| 5fkm | TDC | Tetracycline repressor protein class D | / | 0.444 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.443 | |
| 1e79 | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.443 | |
| 1e79 | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.443 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.443 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.443 | |
| 3lpg | Z78 | Beta-glucuronidase | 3.2.1.31 | 0.443 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.443 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.443 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.443 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.443 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.442 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 1i5e | U5P | Uracil phosphoribosyltransferase | / | 0.442 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.442 | |
| 1xpq | FAD | Polyamine oxidase FMS1 | / | 0.442 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.442 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.442 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.442 | |
| 3dlp | 174 | 4-chlorobenzoyl CoA ligase | / | 0.442 | |
| 3g6z | A7T | Renin | 3.4.23.15 | 0.442 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.442 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.442 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.442 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.442 | |
| 4dja | FAD | (6-4) photolyase | / | 0.442 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.442 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.442 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.441 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.441 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.441 | |
| 2rir | NAP | Dipicolinate synthase subunit A | / | 0.441 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.441 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 4e2b | FMN | Dehydrogenase | / | 0.441 | |
| 4eqs | COA | Coenzyme A disulfide reductase | / | 0.441 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.441 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.441 | |
| 4xr9 | NAD | CalS8 | / | 0.441 | |
| 1a9p | 9DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.440 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.440 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.440 | |
| 2zts | ADP | Uncharacterized protein | / | 0.440 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.440 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.440 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.440 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.440 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.440 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.440 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.440 |