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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3kaqFMNFlavodoxin

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3kaqFMNFlavodoxin/1.000
3kapFMNFlavodoxin/0.647
1fx1FMNFlavodoxin/0.629
1j9gFMNFlavodoxin/0.617
2fx2FMNFlavodoxin/0.617
1azlFMNFlavodoxin/0.598
1akuFMNFlavodoxin/0.586
1wsbFMNFlavodoxin/0.586
1akrFMNFlavodoxin/0.584
3f90FMNFlavodoxin/0.569
1j8qFMNFlavodoxin/0.565
1akwFMNFlavodoxin/0.560
3f6rFMNFlavodoxin/0.559
4fx2FMNFlavodoxin/0.550
1xyvFMNFlavodoxin/0.549
2whqHI6Acetylcholinesterase3.1.1.70.538
4n82FMNRibonucleotide reductase (NrdI family protein), putative/0.531
5fx2FMNFlavodoxin/0.529
3f6sFMNFlavodoxin/0.524
1bu5RBFFlavodoxin/0.522
1c7fFMNFlavodoxin/0.520
5xr8FMNCannabinoid receptor 1/0.518
4y7cFMNNADPH--cytochrome P450 reductase/0.517
4araC56Acetylcholinesterase3.1.1.70.514
2fcrFMNFlavodoxin/0.509
5tgzFMNCannabinoid receptor 1/0.509
5xraFMNCannabinoid receptor 1/0.509
1xyyFMNFlavodoxin/0.506
2v5uFMNFlavodoxin/0.502
4ey6GNTAcetylcholinesterase3.1.1.70.498
1ahnFMNFlavodoxin 1/0.496
3pkeY10Methionine aminopeptidase 2/0.496
1touB1VFatty acid-binding protein, adipocyte/0.495
1j9zFADNADPH--cytochrome P450 reductase/0.494
3mauEXTPutative sphingosine-1-phosphate lyase/0.493
1x2eATXProline iminopeptidase3.4.11.50.491
4oxxFMNCindoxin/0.491
1qtiGNTAcetylcholinesterase3.1.1.70.490
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.490
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.490
3pkbY16Methionine aminopeptidase 2/0.490
4d9eLCSD-cysteine desulfhydrase/0.490
2bn4FMNNADPH--cytochrome P450 reductase/0.489
1pq944BOxysterols receptor LXR-beta/0.488
3ojxFMNNADPH--cytochrome P450 reductase/0.488
4jt91NSNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.488
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.486
1q84TZ4Acetylcholinesterase3.1.1.70.486
2a9z26AAdenosine kinase2.7.1.200.486
3mauPLRPutative sphingosine-1-phosphate lyase/0.486
4s1iPLPPyridoxal kinase, putative/0.486
4d965PAD-cysteine desulfhydrase/0.485
2onfCOAUncharacterized protein/0.484
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.484
4b63NAPL-ornithine N(5)-monooxygenase/0.483
3fhxPLPPyridoxal kinase2.7.1.350.482
3zkyWT4Isopenicillin N synthase1.21.3.10.482
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.481
2gmsP0PPutative pyridoxamine 5-phosphate-dependent dehydrase/0.481
2vf3GVS4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.481
4bmpFMNProtein NrdI/0.481
4u163C0Muscarinic acetylcholine receptor M3/0.481
2fznFADBifunctional protein PutA1.5.5.20.480
3eszFMNFlavodoxin/0.480
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.480
1ja0FMNNADPH--cytochrome P450 reductase/0.479
1zisINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.479
2a2dANPN-acetylgalactosamine kinase2.7.1.1570.479
4gdpFADPolyamine oxidase FMS1/0.479
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.479
1lvu9PPPurine nucleoside phosphorylase2.4.2.10.478
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.478
3wqmB29Diterpene synthase3.1.7.80.478
4a16H34Acetylcholinesterase3.1.1.70.478
1k4gAIQQueuine tRNA-ribosyltransferase2.4.2.290.477
1p0pBCHCholinesterase3.1.1.80.477
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.477
1yw8A75Methionine aminopeptidase 2/0.477
2xi4AFTAcetylcholinesterase3.1.1.70.477
4k37SAMAnaerobic sulfatase-maturating enzyme1.8.980.477
1ja1FMNNADPH--cytochrome P450 reductase/0.476
1obnASVIsopenicillin N synthase1.21.3.10.476
1rkwPNTHTH-type transcriptional regulator QacR/0.476
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.476
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.476
4uugPXGBranched-chain amino acid aminotransferase, putative/0.476
4xnw2IDP2Y purinoceptor 1/0.476
1gjrFADFerredoxin--NADP reductase1.18.1.20.475
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.475
3c1oNAPEugenol synthase/0.475
3fpkFADFerredoxin-NADP reductase/0.475
3fr4F8AFatty acid-binding protein, adipocyte/0.475
4jxzATPGlutamine--tRNA ligase6.1.1.180.475
2mokFMNFlavodoxin 1/0.474
2qimZEAClass 10 plant pathogenesis-related protein/0.474
3iu7FCDMethionine aminopeptidase 2/0.474
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.474
3v0p4GWHisto-blood group ABO system transferase/0.474
1gky5GPGuanylate kinase2.7.4.80.473
1ofvFMNFlavodoxin/0.473
2cekN8TAcetylcholinesterase3.1.1.70.473
3fr5I4AFatty acid-binding protein, adipocyte/0.473
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.473
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.472
2g1n1IGRenin3.4.23.150.472
3jusBCDLanosterol 14-alpha demethylase1.14.13.700.472
3nu03TUDihydrofolate reductase1.5.1.30.472
4l5aTBNS-methyl-5'-thioadenosine phosphorylase/0.472
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.471
1m9hNAD2,5-diketo-D-gluconic acid reductase A1.1.1.3460.471
1w6rGNTAcetylcholinesterase3.1.1.70.471
2ea2F77Methionine aminopeptidase 2/0.471
3e6eDCSAlanine racemase/0.471
3zj6VM2Raucaffricine-O-beta-D-glucosidase3.2.1.1250.471
3klbFMNUncharacterized protein/0.470
3u5ySCGRaucaffricine-O-beta-D-glucosidase3.2.1.1250.470
1fmjRTLRetinol dehydratase/0.469
1gawFADFerredoxin/0.469
1kw8BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.469
1oxoIK2Aspartate aminotransferase, mitochondrial2.6.1.10.469
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.469
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.469
4bfxZVXPantothenate kinase2.7.1.330.469
1kwcBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.468
1towCRZFatty acid-binding protein, adipocyte/0.468
1x8lOXRRetinol dehydratase/0.468
2clmF6FTryptophan synthase alpha chain/0.468
2pswCOAN-alpha-acetyltransferase 50/0.468
2rehFADNitroalkane oxidase1.7.3.10.468
3gncQQQGlutaryl-CoA dehydrogenase/0.468
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.467
1cs4FOKAdenylate cyclase type 2/0.466
1cs4FOKAdenylate cyclase type 5/0.466
1cznFMNFlavodoxin/0.466
1ex75GPGuanylate kinase2.7.4.80.466
2aq7TL53-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.466
3esyFMNFlavodoxin/0.466
3pkaY02Methionine aminopeptidase 2/0.466
3wquATPCell division protein FtsA/0.466
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.465
1rsgFADPolyamine oxidase FMS1/0.465
1votHUPAcetylcholinesterase3.1.1.70.465
2po3T4K4-dehydrase/0.465
2w6pOA4Biotin carboxylase6.3.4.140.465
3hr4FMNNitric oxide synthase, inducible1.14.13.390.465
3zv7NHGAcetylcholinesterase3.1.1.70.465
4b67NAPL-ornithine N(5)-monooxygenase/0.465
1dx6GNTAcetylcholinesterase3.1.1.70.464
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.464
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.464
1qpl587Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.463
2ga2A19Methionine aminopeptidase 2/0.463
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
3pn1IVHDNA ligase/0.463
3w2fNADNADH-cytochrome b5 reductase 31.6.2.20.463
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.463
1nzq162Prothrombin3.4.21.50.462
1xvvCCQL-carnitine CoA-transferase/0.462
3ekuCY9Actin-5C/0.462
3ge7AFQQueuine tRNA-ribosyltransferase2.4.2.290.462
3kozZ97D-ornithine 4,5-aminomutase subunit beta/0.462
3ox279XRibosyldihydronicotinamide dehydrogenase [quinone]/0.462
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.462
4b65NDPL-ornithine N(5)-monooxygenase/0.462
4flkY10Methionine aminopeptidase 1/0.462
4glx0XSDNA ligase6.5.1.20.462
4kxjP34Nucleoprotein/0.462
1e66HUXAcetylcholinesterase3.1.1.70.461
1zgbA1EAcetylcholinesterase3.1.1.70.461
1zgcA2EAcetylcholinesterase3.1.1.70.461
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.461
2fzmFADBifunctional protein PutA1.5.5.20.461
2g8yNADHydroxycarboxylate dehydrogenase B/0.461
2ok8FADFerredoxin--NADP reductase, apicoplast/0.461
2uuk897Prothrombin3.4.21.50.461
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
3junAJDPhenazine biosynthesis protein A/B/0.461
4bftZVTPantothenate kinase2.7.1.330.461
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.461
5fd8A5APutative carboxypeptidase yocD/0.461
1a9cGTPGTP cyclohydrolase 13.5.4.160.460
1h42FADFerredoxin--NADP reductase1.18.1.20.460
1ppjANYCytochrome b/0.460
2rc6FADFerredoxin--NADP reductase/0.460
2xjeU5PCytosolic purine 5'-nucleotidase3.1.3.50.460
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.460
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.460
3ox1695Ribosyldihydronicotinamide dehydrogenase [quinone]/0.460
3wtiCT4Acetylcholine-binding protein/0.460
4b1iA8PPoly(ADP-ribose) glycohydrolase3.2.1.1430.460
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.460
4i101BSBeta-secretase 13.4.23.460.460
4jt81NRNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.460
4x9dU5PUncharacterized protein MJ1435/0.460
4xczT3QQdtf/0.460
1ut6A8NAcetylcholinesterase3.1.1.70.459
2f2sCOAAcetyl-CoA acetyltransferase, mitochondrial2.3.1.90.459
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3rsv3RSBeta-secretase 13.4.23.460.459
4e32DWNMethyltransferase/0.459
4f7iNAD3-isopropylmalate dehydrogenase1.1.1.850.459
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
4o9cCOAAcetyl-CoA acetyltransferase2.3.1.90.459
4pmjNAPPutative oxidoreductase/0.459
4u9yCOAAlpha-tubulin N-acetyltransferase 1/0.459
1lkeDOGBilin-binding protein/0.458
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.458
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.458
2hxzH7JCathepsin S3.4.22.270.458
2pncCLUPrimary amine oxidase, liver isozyme/0.458
3c74ANUUridine phosphorylase2.4.2.30.458
3q9bB3NAcetylpolyamine amidohydrolase/0.458
4fliY16Methionine aminopeptidase 1/0.458
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.458
1kw6BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.457
1qrsATPGlutamine--tRNA ligase6.1.1.180.457
1upw444Oxysterols receptor LXR-beta/0.457
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.457
2aotSAHHistamine N-methyltransferase2.1.1.80.457
2bf4FMNNADPH--cytochrome P450 reductase/0.457
2evmFC2Methionine aminopeptidase/0.457
2gywOBIAcetylcholinesterase3.1.1.70.457
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.457
2v8pCDP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.457
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.457
2zevIPEGeranylgeranyl pyrophosphate synthase/0.457
3oqfS51Renin3.4.23.150.457
3rviRVIBeta-secretase 13.4.23.460.457
3u57DH8Raucaffricine-O-beta-D-glucosidase3.2.1.1250.457
3zc3FADFerredoxin--NADP reductase1.18.1.20.457
3zj7C1KStrictosidine-O-beta-D-glucosidase3.2.1.1050.457
4f3gKAIGlutamate receptor 3/0.457
4tnzTTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.457
1s3uTQDDihydrofolate reductase1.5.1.30.456
2a2cADPN-acetylgalactosamine kinase2.7.1.1570.456
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.456
2rd2QSIGlutamine--tRNA ligase6.1.1.180.456
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
3ndjJHZMethyltransferase/0.456
4e2wJHZMethyltransferase/0.456
1m4iCOAAminoglycoside 2'-N-acetyltransferase2.3.10.455
1odcA8BAcetylcholinesterase3.1.1.70.455
1pd9CO4Dihydrofolate reductase1.5.1.30.455
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.455
2uxhQUEHTH-type transcriptional regulator TtgR/0.455
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.455
3d4bDZDNAD-dependent protein deacetylase/0.455
3rykTYDdTDP-4-dehydrorhamnose 3,5-epimerase/0.455
1bx0FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.454
1thz326Bifunctional purine biosynthesis protein PURH2.1.2.30.454
1w19T1P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.454
2aouCQAHistamine N-methyltransferase2.1.1.80.454
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.454
2ha6SCKAcetylcholinesterase3.1.1.70.454
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.454
3vilSA0Beta-glucosidase/0.454
4bfvZVVPantothenate kinase2.7.1.330.454
4br3U85Choline kinase alpha2.7.1.320.454
4ixt1H1Halohydrin dehalogenase/0.454
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.453
1rftPXMPyridoxal kinase2.7.1.350.453
1ycfFMNNitric oxide reductase10.453
2hp2KE4Glutamate-1-semialdehyde 2,1-aminomutase5.4.3.80.453
2il2LIXRenin3.4.23.150.453
2o3uNGDADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.453
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3koyZ97D-ornithine 4,5-aminomutase subunit beta/0.453
3qftFADNADPH--cytochrome P450 reductase/0.453
3tfyCOAN-alpha-acetyltransferase 502.3.10.453
4c717RD3-oxoacyl-ACP synthase/0.453
4jtqNAPAldo-keto reductase family 1 member C2/0.453
4mbsMRVC-C chemokine receptor type 5/0.453
1kqnNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.452
1pqc444Oxysterols receptor LXR-beta/0.452
1sg0STLRibosyldihydronicotinamide dehydrogenase [quinone]/0.452
1x1bSAHC-20 methyltransferase/0.452
2bf4FADNADPH--cytochrome P450 reductase/0.452
2fjeFADAdenylylsulfate reductase, subunit A (AprA)/0.452
3adaNADSubunit alpha of sarocosine oxidase/0.452
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3p0eBAUUridine phosphorylase 22.4.2.30.452
3ufl508Beta-secretase 13.4.23.460.452
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.452
4b1hAR6Poly(ADP-ribose) glycohydrolase3.2.1.1430.452
4bfzZVZPantothenate kinase2.7.1.330.452
4fl0PLPAminotransferase ALD1, chloroplastic2.6.10.452
4h6pFMNChromate reductase/0.452
4ia05BBcGMP-specific 3',5'-cyclic phosphodiesterase/0.452
4na4A1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.452
4to4DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.452
1cnfFADNitrate reductase [NADH]1.7.1.10.451
1frbZSTAldose reductase-related protein 2/0.451
1fw0KAIGlutamate receptor 2/0.451
1lnmDTXBilin-binding protein/0.451
1w6jR71Lanosterol synthase5.4.99.70.451
1y52BTNAvidin-related protein 4/5/0.451
1y5xE89Queuine tRNA-ribosyltransferase2.4.2.290.451
2hxdDUPdCTP deaminase, dUMP-forming3.5.4.300.451
2vbpVB1Isopenicillin N synthase1.21.3.10.451
2x91LPRAngiotensin-converting enzyme3.4.15.10.451
2xq0BESLeukotriene A-4 hydrolase homolog3.3.2.60.451
3ce0P34Poly [ADP-ribose] polymerase 32.4.2.300.451
4rnxFMNNADPH dehydrogenase 11.6.99.10.451
4to3DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.451
4zj8SUVOrexin receptor type 1/0.451
4u140HKMuscarinic acetylcholine receptor M3/0.451
3uonQNBMuscarinic acetylcholine receptor M2/0.451
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.450
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.450
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.450
1rpwDIDHTH-type transcriptional regulator QacR/0.450
1xp8AGSProtein RecA/0.450
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.450
2qmzLDPRibosyldihydronicotinamide dehydrogenase [quinone]/0.450
2wo7ASVIsopenicillin N synthase1.21.3.10.450
2xfyACXBeta-amylase3.2.1.20.450
3h3t16HCollagen type IV alpha-3-binding protein/0.450
3tfjTHGDimethylsulfonioproprionate demethylase DmdA2.1.1.2690.450
3ziuLSSLeucyl-tRNA synthetase/0.450
4dbw511Aldo-keto reductase family 1 member C3/0.450
4jjkFOLFormate--tetrahydrofolate ligase/0.450
5jy1NADPutative short-chain dehydrogenase/reductase/0.450
1lcwSHMStreptavidin/0.449
1r58AO5Methionine aminopeptidase 2/0.449
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.449
1trgCB3Thymidylate synthase/0.449
2bpoFADNADPH--cytochrome P450 reductase/0.449
2cbqTH2Neocarzinostatin/0.449
2g1y5IGRenin3.4.23.150.449
2gvdFKPAdenylate cyclase type 2/0.449
2gvdFKPAdenylate cyclase type 5/0.449
2yhuWHFPteridine reductase/0.449
2yvwEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.449
3hiiPNTAmiloride-sensitive amine oxidase [copper-containing]/0.449
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase/0.449
4af6FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.449
4b64NAPL-ornithine N(5)-monooxygenase/0.449
4bprFADFerredoxin--NADP reductase1.18.1.20.449
4i1c1BEBeta-secretase 13.4.23.460.449
4nbiD3YD-tyrosyl-tRNA(Tyr) deacylase/0.449
4rxrDCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.449
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.449
5cflC2EStimulator of interferon genes protein/0.449
1enoNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.448
1g63FMNEpidermin decarboxylase4.1.10.448
1mvtDTMDihydrofolate reductase1.5.1.30.448
1n3sGTPGTP cyclohydrolase 13.5.4.160.448
1opmIYGPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.448
1x1cSAHC-20 methyltransferase/0.448
1yciNDFHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.448
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.448
2a3cPNXEndochitinase B13.2.1.140.448
2w3mFOLDihydrofolate reductase1.5.1.30.448
2zi53L1Deoxycytidine kinase2.7.1.740.448
3c1kT15Prothrombin3.4.21.50.448
3eon341Glutaryl-CoA dehydrogenase/0.448
3gc52MQQueuine tRNA-ribosyltransferase2.4.2.290.448
3n3bFMNProtein NrdI/0.448
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.448
3rdqDTBStreptavidin/0.448
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.448
4ax8SAMO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.448
4b1e6T6Beta-secretase 13.4.23.460.448
4b52RDFBacillolysin/0.448
4jdcNADProbable pyrroline-5-carboxylate dehydrogenase RocA/0.448
4layI63Peptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.448
4mlp2CXCryptochrome-2/0.448
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.448
4to6TTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.448
5a8aADPRiboflavin biosynthesis protein RibF2.7.1.260.448
5c4fUPGHisto-blood group ABO system transferase/0.448
1b2lNDCAlcohol dehydrogenase1.1.1.10.447
1gpnHUBAcetylcholinesterase3.1.1.70.447
1j9zFMNNADPH--cytochrome P450 reductase/0.447
1nc9IMIStreptavidin/0.447
1pl6572Sorbitol dehydrogenase1.1.1.140.447
1yryMSGPurine nucleoside phosphorylase2.4.2.10.447
2g247IGRenin3.4.23.150.447
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.447
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
2xuoTZ4Acetylcholinesterase3.1.1.70.447
3h3qH13Collagen type IV alpha-3-binding protein/0.447
3h3r14HCollagen type IV alpha-3-binding protein/0.447
3hl0NADMaleylacetate reductase/0.447
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3sff0DIHistone deacetylase 83.5.1.980.447
3zg6APRNAD-dependent protein deacetylase sirtuin-63.5.10.447
4du6GTPGTP cyclohydrolase 1/0.447
4gh10WXQueuine tRNA-ribosyltransferase2.4.2.290.447
4rvfTYDD-mycarose 3-C-methyltransferase/0.447
4ubtCOASteroid 3-ketoacyl-CoA thiolase/0.447
4x5fFOLDihydrofolate reductase1.5.1.30.447
5esdTDP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.447
5irnADPNucleotide binding oligomerization domain containing 2/0.447
3ny9JSZBeta-2 adrenergic receptor/0.447
1gt5BZQOdorant-binding protein/0.446
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.446
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.446
1nhkCMPNucleoside diphosphate kinase2.7.4.60.446
1p33MTXPteridine reductase 11.5.1.330.446
1ry0PG2Aldo-keto reductase family 1 member C3/0.446
1ulbGUNPurine nucleoside phosphorylase2.4.2.10.446
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.446
2clfF6FTryptophan synthase alpha chain/0.446
2fhjH4ZFormylmethanofuran--tetrahydromethanopterin formyltransferase2.3.1.1010.446
2gfxPMN3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.446
2q94A04Methionine aminopeptidase/0.446
2vb8TLM3-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.446
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.446
2zu9GDPMannosyl-3-phosphoglycerate synthase2.4.1.2170.446
3ai0PNWBeta-glucosidase/0.446
3aosJH2Hemolymph juvenile hormone binding protein/0.446
3eksCY9Actin-5C/0.446
3ho2N323-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.446
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.446
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.446
4b1jA1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.446
4c73TLH3-oxoacyl-ACP synthase/0.446
4cf6CBDNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
4j1e1HMBeta-secretase 13.4.23.460.446
4n9qFMNFMN-dependent NADH-azoreductase 1/0.446
1eirBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.445
1jqdSAHHistamine N-methyltransferase2.1.1.80.445
1kmyBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.445
1ni12C5Protein farnesyltransferase subunit beta2.5.1.580.445
1qrtATPGlutamine--tRNA ligase6.1.1.180.445
1qsnCOAHAT A1/0.445
1vfsDCSAlanine racemase/0.445
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
1ycgFMNNitric oxide reductase10.445
2bu9HFVIsopenicillin N synthase1.21.3.10.445
2g6pHM2Methionine aminopeptidase 1/0.445
2x9dITCTetracycline repressor protein class D/0.445
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.445
3bsyACOUDP-N-acetylbacillosamine N-acetyltransferase2.3.1.2030.445
3c14FOKAdenylate cyclase type 2/0.445
3c14FOKAdenylate cyclase type 5/0.445
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.445
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.445
3ho9N3A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.445
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.445
4bb3KKAIsopenicillin N synthase1.21.3.10.445
4c4oNADSADH/0.445
4ixd1HVIntegrin alpha-L/0.445
4k38SAMAnaerobic sulfatase-maturating enzyme1.8.980.445
4m6l21VDihydrofolate reductase1.5.1.30.445
1ogiFADFerredoxin--NADP reductase1.18.1.20.444
1qiqACCIsopenicillin N synthase1.21.3.10.444
1t7o152Carnitine O-acetyltransferase2.3.1.70.444
1tcoFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.444
1tcoFK5Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform3.1.3.160.444
1w19T5P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.444
1w87FADFerredoxin--NADP reductase1.18.1.20.444
1yw7A41Methionine aminopeptidase 2/0.444
2ckmAA7Acetylcholinesterase3.1.1.70.444
2g0gSP0Peroxisome proliferator-activated receptor gamma/0.444
2o7pNAPRiboflavin biosynthesis protein RibD/0.444
2p98YE7Methionine aminopeptidase/0.444
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.444
2vcmM11Isopenicillin N synthase1.21.3.10.444
2vuuNAPNitrogen metabolite repression protein nmrA/0.444
2w4qCBWProstaglandin reductase 21.3.1.480.444
2y035FWBeta-1 adrenergic receptor/0.444
3buvNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.444
3c36KAIGlutamate receptor ionotropic, kainate 1/0.444
3kfmKAIGlutamate receptor 4/0.444
3lutNAPVoltage-gated potassium channel subunit beta-2/0.444
3n39FMNProtein NrdI/0.444
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.444
3oqkS52Renin3.4.23.150.444
3pkdY10Methionine aminopeptidase 2/0.444
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.444
4bcsBTNAvidin-related protein 4/5/0.444
4d9fDCSD-cysteine desulfhydrase/0.444
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.444
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.444
4qoeFADRibosyldihydronicotinamide dehydrogenase [quinone]/0.444
5fe112QHistone acetyltransferase KAT2B2.3.1.480.444
5cxv0HKMuscarinic acetylcholine receptor M1/0.444
1dr3HBIDihydrofolate reductase1.5.1.30.443
1efzPRFQueuine tRNA-ribosyltransferase2.4.2.290.443
1ix1BB2Peptide deformylase/0.443
1queFADFerredoxin--NADP reductase1.18.1.20.443
1uhhCZPAequorin-2/0.443
1wooTHGAminomethyltransferase/0.443
2ab8MTPAdenosine kinase2.7.1.200.443
2bb3SAHCobalamin biosynthesis precorrin-6Y methylase (CbiE)/0.443
2q96A18Methionine aminopeptidase/0.443
2re8GSUGlutamine--tRNA ligase6.1.1.180.443
2v2vV124-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.443
2xlrNAPPutative flavin-containing monooxygenase/0.443
2xugTZ4Acetylcholinesterase3.1.1.70.443
3b1dPLSBetaC-S lyase/0.443
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3l3mA92Poly [ADP-ribose] polymerase 12.4.2.300.443
3s7bNH5N-lysine methyltransferase SMYD2/0.443
3wqtANPCell division protein FtsA/0.443
4ba5PXGProbable aminotransferase/0.443
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.443
4j7hTRHPCZA361.3/0.443
4k4eK4ETankyrase-12.4.2.300.443
4kfqKFQGlutamate receptor ionotropic, NMDA 1/0.443
4lcnGNGCytidine and deoxycytidylate deaminase zinc-binding region/0.443
4oex5EOcGMP-specific 3',5'-cyclic phosphodiesterase/0.443
4rp8ASCAscorbate-specific PTS system EIIC component/0.443
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.443
4xnhACON-terminal acetyltransferase A complex subunit NAT52.3.10.443
5cc9DDFDihydrofolate reductase1.5.1.30.443
1h50FMNPentaerythritol tetranitrate reductase/0.442
1hb3SCVIsopenicillin N synthase1.21.3.10.442
1kw9BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.442
1nqw5YL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.442
1oj4CDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.442
1qjfACSIsopenicillin N synthase1.21.3.10.442
1rvvINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.442
2dhfDZFDihydrofolate reductase1.5.1.30.442
2iko7IGRenin3.4.23.150.442
2iviACWIsopenicillin N synthase1.21.3.10.442
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.442
2p4sDIHAGAP005945-PA/0.442
2v58LZJBiotin carboxylase6.3.4.140.442
2xukTZ5Acetylcholinesterase3.1.1.70.442
2xysSY9Soluble acetylcholine receptor/0.442
3c15FOKAdenylate cyclase type 2/0.442
3c15FOKAdenylate cyclase type 5/0.442
3f7uAG4Carbonic anhydrase 44.2.1.10.442
3hv3R49Mitogen-activated protein kinase 14/0.442
3o73O73Ribosyldihydronicotinamide dehydrogenase [quinone]/0.442
3q43D66M1 family aminopeptidase3.4.110.442
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.442
3vmmP0DAlanine--anticapsin ligase/0.442
4af7FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.442
4b68NAPL-ornithine N(5)-monooxygenase/0.442
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.442
4h6uACOAlpha-tubulin N-acetyltransferase 1/0.442
4kebFOLDihydrofolate reductase1.5.1.30.442
4rphGDUUDP-galactopyranose mutase5.4.99.90.442
1cjvFOKAdenylate cyclase type 2/0.441
1cjvFOKAdenylate cyclase type 5/0.441
1e2nRCAThymidine kinase/0.441
1gm7PNNPenicillin G acylase3.5.1.110.441
1j37X8ZAngiotensin-converting enzyme3.4.15.10.441
1lgtBP3Biphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.441
1lv89PPPurine nucleoside phosphorylase2.4.2.10.441
1n5vNOMActVA 6 protein/0.441
1n9mBTNStreptavidin/0.441
1qgzFADFerredoxin--NADP reductase1.18.1.20.441
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.441
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.441
2gg8U15Methionine aminopeptidase/0.441
2ggbU17Methionine aminopeptidase/0.441
2gl0ADNUncharacterized protein/0.441
2nnqT4BFatty acid-binding protein, adipocyte/0.441
3bt9DEQHTH-type transcriptional regulator QacR/0.441
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.441
3fp0FP015-O-acetyltransferase/0.441
3jqrFADFerredoxin--NADP reductase, apicoplast/0.441
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.441
3o57ZG2cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.441
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.441
3pkcY08Methionine aminopeptidase 2/0.441
3v0n4GWHisto-blood group ABO system transferase/0.441
4bj9UHBTankyrase-22.4.2.300.441
4c43FADFerredoxin--NADP reductase1.18.1.20.441
4da8BG2Purine nucleoside phosphorylase DeoD-type2.4.2.10.441
4jsr1NQNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.441
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.441
4xo7NAPAldo-keto reductase family 1 member C2/0.441
4zqcF6FTryptophan synthase alpha chain/0.441
1c7oPPGHemolysin/0.440
1f20FADNitric oxide synthase, brain1.14.13.390.440
1hfqMOTDihydrofolate reductase1.5.1.30.440
1ktsC24Prothrombin3.4.21.50.440
1xzqFONtRNA modification GTPase MnmE3.6.50.440
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.440
2bd0BIOSepiapterin reductase/0.440
2ea4F79Methionine aminopeptidase 2/0.440
2iu8UD1UDP-3-O-acylglucosamine N-acyltransferase2.3.10.440
2j3qTFLAcetylcholinesterase3.1.1.70.440
2rqfJH3Hemolymph juvenile hormone binding protein/0.440
2x92X92Angiotensin-converting enzyme3.4.15.10.440
3arvSAUChitinase A/0.440
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.440
3mhpFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.440
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.440
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.440
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.440
3uzzASD3-oxo-5-beta-steroid 4-dehydrogenase/0.440
4ho6UTPGlucose-1-phosphate thymidylyltransferase/0.440
4jxxATPGlutamine--tRNA ligase6.1.1.180.440
4kniE1ECarbonic anhydrase 24.2.1.10.440
4nhyPD2Prolyl 3-hydroxylase OGFOD11.14.110.440
4nv10FXFormyl transferase/0.440
4u3jGTPTubulin beta chain/0.440
4wljIK2Kynurenine--oxoglutarate transaminase 12.6.1.70.440