sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3kap | FMN | Flavodoxin |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3kap | FMN | Flavodoxin | / | 1.000 | |
| 3kaq | FMN | Flavodoxin | / | 0.590 | |
| 1j9g | FMN | Flavodoxin | / | 0.585 | |
| 1fx1 | FMN | Flavodoxin | / | 0.577 | |
| 2fx2 | FMN | Flavodoxin | / | 0.573 | |
| 1wsb | FMN | Flavodoxin | / | 0.571 | |
| 1azl | FMN | Flavodoxin | / | 0.558 | |
| 1xyv | FMN | Flavodoxin | / | 0.553 | |
| 3f6r | FMN | Flavodoxin | / | 0.547 | |
| 1bu5 | RBF | Flavodoxin | / | 0.538 | |
| 1xyy | FMN | Flavodoxin | / | 0.536 | |
| 3f90 | FMN | Flavodoxin | / | 0.522 | |
| 1j8q | FMN | Flavodoxin | / | 0.521 | |
| 5tgz | FMN | Cannabinoid receptor 1 | / | 0.519 | |
| 1aku | FMN | Flavodoxin | / | 0.516 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.515 | |
| 4fx2 | FMN | Flavodoxin | / | 0.514 | |
| 3f6s | FMN | Flavodoxin | / | 0.509 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.509 | |
| 1c7f | FMN | Flavodoxin | / | 0.506 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.500 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.499 | |
| 4n82 | FMN | Ribonucleotide reductase (NrdI family protein), putative | / | 0.496 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.496 | |
| 2mok | FMN | Flavodoxin 1 | / | 0.495 | |
| 1sg0 | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.494 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.494 | |
| 1akr | FMN | Flavodoxin | / | 0.492 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.492 | |
| 5xra | FMN | Cannabinoid receptor 1 | / | 0.491 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.489 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.489 | |
| 4h6p | FMN | Chromate reductase | / | 0.489 | |
| 4oxx | FMN | Cindoxin | / | 0.488 | |
| 1akw | FMN | Flavodoxin | / | 0.486 | |
| 1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.485 | |
| 2v5u | FMN | Flavodoxin | / | 0.484 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.483 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.482 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.482 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.481 | |
| 4kxj | P34 | Nucleoprotein | / | 0.481 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 3eks | CY9 | Actin-5C | / | 0.480 | |
| 1xh7 | R96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.479 | |
| 1czn | FMN | Flavodoxin | / | 0.478 | |
| 2fcr | FMN | Flavodoxin | / | 0.477 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.477 | |
| 2ct8 | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.475 | |
| 2po3 | T4K | 4-dehydrase | / | 0.475 | |
| 3e6e | DCS | Alanine racemase | / | 0.475 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.475 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.473 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.473 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.473 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.473 | |
| 3clr | FAD | Electron transfer flavoprotein subunit alpha | / | 0.471 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.471 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.471 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.470 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.470 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.470 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.470 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 3zj7 | C1K | Strictosidine-O-beta-D-glucosidase | 3.2.1.105 | 0.470 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.470 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.469 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.469 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.469 | |
| 3rdq | DTB | Streptavidin | / | 0.469 | |
| 3wqt | ANP | Cell division protein FtsA | / | 0.469 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.468 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 3n39 | FMN | Protein NrdI | / | 0.468 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.468 | |
| 4oex | 5EO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.468 | |
| 4y7c | FMN | NADPH--cytochrome P450 reductase | / | 0.468 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.467 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.467 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.467 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1nzy | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.466 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.466 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.465 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.465 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.465 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.465 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.465 | |
| 4kfq | KFQ | Glutamate receptor ionotropic, NMDA 1 | / | 0.465 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.464 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.464 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.464 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.464 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.464 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.464 | |
| 1pl6 | 572 | Sorbitol dehydrogenase | 1.1.1.14 | 0.463 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.463 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.463 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.463 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 1ahn | FMN | Flavodoxin 1 | / | 0.461 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.461 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.461 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 3esz | FMN | Flavodoxin | / | 0.461 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.460 | |
| 3jqr | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.460 | |
| 3ojw | FAD | NADPH--cytochrome P450 reductase | / | 0.460 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.460 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.460 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.459 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.459 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 3qfr | FMN | NADPH--cytochrome P450 reductase | / | 0.459 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.459 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.459 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.459 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.458 | |
| 1ix1 | BB2 | Peptide deformylase | / | 0.458 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 3arv | SAU | Chitinase A | / | 0.458 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4b1j | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.458 | |
| 4du6 | GTP | GTP cyclohydrolase 1 | / | 0.458 | |
| 4h6u | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.458 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.457 | |
| 3esy | FMN | Flavodoxin | / | 0.457 | |
| 3vmm | P0D | Alanine--anticapsin ligase | / | 0.457 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.457 | |
| 4lrr | CF9 | Thymidylate synthase | / | 0.457 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.456 | |
| 2bpo | FAD | NADPH--cytochrome P450 reductase | / | 0.456 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 3e8x | NAP | BH1520 protein | / | 0.456 | |
| 3hr4 | FMN | Nitric oxide synthase, inducible | 1.14.13.39 | 0.456 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.456 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.456 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.456 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.456 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.455 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1m9h | NAD | 2,5-diketo-D-gluconic acid reductase A | 1.1.1.346 | 0.455 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.455 | |
| 1thz | 326 | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.455 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.455 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.455 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.455 | |
| 3clu | FAD | Electron transfer flavoprotein subunit alpha | / | 0.455 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.455 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 4tl9 | AGS | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.455 | |
| 4ts7 | ADP | Purine phosphoribosyltransferase (GpT-1) | / | 0.455 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.454 | |
| 1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 0.454 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.454 | |
| 2aj4 | ANP | Galactokinase | 2.7.1.6 | 0.454 | |
| 2v18 | FMN | Dodecin | / | 0.454 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.454 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.454 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.454 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.454 | |
| 3uxv | GUN | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.454 | |
| 5dp2 | NAP | CurF | / | 0.454 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.454 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 2ed4 | FAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.453 | |
| 2f99 | AKV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.453 | |
| 2gfx | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.453 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.453 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.453 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.452 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.452 | |
| 2zts | ADP | Uncharacterized protein | / | 0.452 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.452 | |
| 3tif | ADP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.452 | |
| 3w5u | FAD | Ferredoxin | / | 0.452 | |
| 4af6 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.452 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.452 | |
| 4ubt | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.452 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.451 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.451 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.451 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.451 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.451 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 4dyp | 0MS | Nucleoprotein | / | 0.451 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.451 | |
| 5xr8 | FMN | Cannabinoid receptor 1 | / | 0.451 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.450 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.450 | |
| 1oxo | IK2 | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.450 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.450 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.450 | |
| 3go4 | SAH | Uncharacterized protein | / | 0.450 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.450 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.450 | |
| 1v45 | 3DG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 2ejz | SAH | Diphthine synthase | / | 0.449 | |
| 2fgk | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.449 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.449 | |
| 2vi5 | Y19 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.449 | |
| 3nn6 | HNK | 6-hydroxy-L-nicotine oxidase | / | 0.449 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.449 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.449 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.449 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.449 | |
| 4yek | THM | Thymidine phosphorylase | / | 0.449 | |
| 5a8a | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.449 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.449 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.448 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.448 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.448 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.448 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.448 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.448 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.448 | |
| 3rup | ADP | Biotin carboxylase | 6.3.4.14 | 0.448 | |
| 3w5h | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.448 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.448 | |
| 1amo | FMN | NADPH--cytochrome P450 reductase | / | 0.447 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.447 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.447 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.447 | |
| 2vet | UMP | Thymidylate synthase | / | 0.447 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.447 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 3lut | NAP | Voltage-gated potassium channel subunit beta-2 | / | 0.447 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.447 | |
| 4d9e | LCS | D-cysteine desulfhydrase | / | 0.447 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.447 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1euy | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.446 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 1qpl | 587 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.446 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.446 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.446 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.446 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.446 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.446 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.446 | |
| 3l3l | L3L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.446 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.446 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.446 | |
| 1b2r | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.445 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.445 | |
| 1tvc | FDA | Methane monooxygenase component C | 1.14.13.25 | 0.445 | |
| 1xqp | 8HG | N-glycosylase/DNA lyase | / | 0.445 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.445 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.445 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.445 | |
| 3ojw | FMN | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 3ryk | TYD | dTDP-4-dehydrorhamnose 3,5-epimerase | / | 0.445 | |
| 5doz | NDP | JamJ | / | 0.445 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.444 | |
| 1xh6 | R94 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2o12 | FMN | Chorismate synthase | / | 0.444 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.444 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 3hu2 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.444 | |
| 3jzd | NAD | Maleylacetate reductase | / | 0.444 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.444 | |
| 3upt | TPP | Transketolase | / | 0.444 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.443 | |
| 1mu8 | CDB | Prothrombin | 3.4.21.5 | 0.443 | |
| 1pz0 | NAP | Protein IolS | 1.1.1 | 0.443 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.443 | |
| 1sq5 | ADP | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 1swe | BTN | Streptavidin | / | 0.443 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.443 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.443 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.443 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.443 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.443 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.443 | |
| 3n5y | XFL | Nitric oxide synthase, brain | 1.14.13.39 | 0.443 | |
| 3pdn | SFG | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.443 | |
| 3udq | 09E | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4ayy | 9MX | Prothrombin | 3.4.21.5 | 0.443 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.443 | |
| 4iom | FOL | Formate--tetrahydrofolate ligase | / | 0.443 | |
| 4irn | FAD | AnaB | / | 0.443 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4kln | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.443 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.443 | |
| 1fw0 | KAI | Glutamate receptor 2 | / | 0.442 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.442 | |
| 1ofv | FMN | Flavodoxin | / | 0.442 | |
| 1pz1 | NAP | General stress protein 69 | / | 0.442 | |
| 1rpw | DID | HTH-type transcriptional regulator QacR | / | 0.442 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.442 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 2a3c | PNX | Endochitinase B1 | 3.2.1.14 | 0.442 | |
| 2gz8 | F3F | Orf1a polyprotein | / | 0.442 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.442 | |
| 3egk | M18 | Prothrombin | 3.4.21.5 | 0.442 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.442 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4nwi | CTN | 7-methylguanosine phosphate-specific 5'-nucleotidase | / | 0.442 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.442 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.442 | |
| 5fx2 | FMN | Flavodoxin | / | 0.442 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.441 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1p5r | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.441 | |
| 1u2r | SO1 | Elongation factor 2 | / | 0.441 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.441 | |
| 2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.441 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.441 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.441 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.441 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.441 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2wmd | ZZ0 | NmrA-like family domain-containing protein 1 | / | 0.441 | |
| 3ge7 | AFQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.441 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 3hj9 | FMN | Uncharacterized protein | / | 0.441 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.441 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.441 | |
| 3r95 | ACO | MccE protein | / | 0.441 | |
| 4azy | 7F3 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4b45 | GSP | Tubulin-like protein CetZ2 | / | 0.441 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.441 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4glx | 0XS | DNA ligase | 6.5.1.2 | 0.441 | |
| 4jzr | 4JR | Egl nine homolog 1 | / | 0.441 | |
| 1d0l | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.440 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1fxv | PNN | Penicillin G acylase | 3.5.1.11 | 0.440 | |
| 1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.440 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1trk | TPP | Transketolase 1 | 2.2.1.1 | 0.440 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.440 | |
| 2ea1 | GPG | Ribonuclease I | 3.1.27.6 | 0.440 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.440 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.440 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.440 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2xlr | NAP | Putative flavin-containing monooxygenase | / | 0.440 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.440 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.440 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.440 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.440 | |
| 3nhp | HGZ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4kwh | NAP | Reductase homolog | / | 0.440 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.440 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.440 |