sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3k9l | GNP | GTPase HRas |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3k9l | GNP | GTPase HRas | / | 1.000 | |
| 2rgg | GNP | GTPase HRas | / | 0.647 | |
| 3kkq | GDP | Ras-related protein M-Ras | / | 0.641 | |
| 4hdq | GNP | Ras-related protein Rap-1b | / | 0.626 | |
| 4lpk | GDP | GTPase KRas | / | 0.624 | |
| 2ce2 | GDP | GTPase HRas | / | 0.621 | |
| 4luc | GDP | GTPase KRas | / | 0.618 | |
| 4xvr | GNP | GTPase HRas | / | 0.615 | |
| 4l8g | GDP | GTPase KRas | / | 0.605 | |
| 4q02 | GDP | GTPase KRas | / | 0.605 | |
| 4xvq | GNP | GTPase HRas | / | 0.605 | |
| 1uad | GNP | Ras-related protein Ral-A | / | 0.600 | |
| 3tgp | GNP | GTPase HRas | / | 0.600 | |
| 3kko | GNP | Ras-related protein M-Ras | / | 0.595 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.583 | |
| 3lbh | GNP | GTPase HRas | / | 0.583 | |
| 4epw | GDP | GTPase KRas | / | 0.582 | |
| 4tq9 | GDP | GTPase KRas | / | 0.579 | |
| 3ddc | GNP | GTPase HRas | / | 0.577 | |
| 4lrw | GDP | GTPase KRas | / | 0.576 | |
| 4wa7 | GDP | GTPase KRas | / | 0.575 | |
| 3i3s | GNP | GTPase HRas | / | 0.573 | |
| 4l9s | GDP | GTPase HRas | / | 0.573 | |
| 4g0n | GNP | GTPase HRas | / | 0.567 | |
| 4dsu | GDP | GTPase KRas | / | 0.564 | |
| 2c5l | GTP | GTPase HRas | / | 0.563 | |
| 4lv6 | GDP | GTPase KRas | / | 0.559 | |
| 3qbt | GNP | Ras-related protein Rab-8A | / | 0.554 | |
| 1n6l | GTP | Ras-related protein Rab-5A | / | 0.552 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.552 | |
| 3tso | GNP | Ras-related protein Rab-25 | / | 0.550 | |
| 2cl6 | CAG | GTPase HRas | / | 0.549 | |
| 4dsn | GCP | GTPase KRas | / | 0.549 | |
| 4epx | GDP | GTPase KRas | / | 0.549 | |
| 3oiv | GNP | GTPase HRas | / | 0.547 | |
| 4ldj | GDP | GTPase KRas | / | 0.547 | |
| 4obe | GDP | GTPase KRas | / | 0.547 | |
| 3k8y | GNP | GTPase HRas | / | 0.544 | |
| 4ql3 | GDP | GTPase KRas | / | 0.544 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.542 | |
| 3lbi | GNP | GTPase HRas | / | 0.542 | |
| 3rs4 | GNP | GTPase HRas | / | 0.538 | |
| 2fg5 | GNP | Ras-related protein Rab-31 | / | 0.537 | |
| 3l8y | GNP | GTPase HRas | / | 0.537 | |
| 4nyi | GNP | GTPase HRas | / | 0.537 | |
| 2rge | GNP | GTPase HRas | / | 0.536 | |
| 3pit | GNP | Ras-related protein M-Ras | / | 0.536 | |
| 4k81 | GTP | GTPase HRas | / | 0.536 | |
| 5b2z | GNP | GTPase HRas | / | 0.536 | |
| 1yu9 | GNP | Ras-related protein Rab-4A | / | 0.535 | |
| 4q03 | GDP | GTPase KRas | / | 0.535 | |
| 2p2l | GDP | Ras-related C3 botulinum toxin substrate 1 | / | 0.534 | |
| 3oiw | GNP | GTPase HRas | / | 0.534 | |
| 2msc | GDP | MHC class I alpha chain | / | 0.528 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.527 | |
| 1lfd | GNP | GTPase HRas | / | 0.526 | |
| 4dlt | GNP | GTPase HRas | / | 0.526 | |
| 4o2r | GDP | GTP-binding protein Rheb | / | 0.526 | |
| 1z0a | GDP | Ras-related protein Rab-2A | / | 0.525 | |
| 3v4f | GNP | GTPase HRas | / | 0.524 | |
| 1x1r | GDP | Ras-related protein M-Ras | / | 0.523 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.522 | |
| 5c46 | GSP | Ras-related protein Rab-11A | / | 0.520 | |
| 4uj3 | GNP | Ras-related protein Rab-11A | / | 0.519 | |
| 2q3f | GNP | Ras-related GTP-binding protein D | / | 0.518 | |
| 3sbd | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.518 | |
| 4nyj | GNP | GTPase HRas | / | 0.518 | |
| 1zd9 | GDP | ADP-ribosylation factor-like protein 8A | / | 0.517 | |
| 2rgb | GNP | GTPase HRas | / | 0.517 | |
| 4dlz | GNP | GTPase HRas | / | 0.516 | |
| 1oix | GDP | Ras-related protein Rab-11A | / | 0.515 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.515 | |
| 3oiu | GNP | GTPase HRas | / | 0.514 | |
| 3x1z | GNP | Ras-related protein Rap-1b | / | 0.514 | |
| 2qme | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.512 | |
| 3x1w | GDP | Ras-related protein Rap-1b | / | 0.511 | |
| 2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.510 | |
| 2ic5 | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.510 | |
| 1tu3 | GNP | Ras-related protein Rab-5A | / | 0.509 | |
| 3vhx | GTP | ADP-ribosylation factor 6 | / | 0.509 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.508 | |
| 4uj5 | GNP | Ras-related protein Rab-11A | / | 0.508 | |
| 3rs5 | GNP | GTPase HRas | / | 0.507 | |
| 3lbn | GNP | GTPase HRas | / | 0.506 | |
| 3ref | GDP | Rho family GTPase | / | 0.506 | |
| 5dif | GNP | GTP-binding nuclear protein Ran | / | 0.506 | |
| 4dxa | GSP | Ras-related protein Rap-1b | / | 0.505 | |
| 1z2a | GDP | Ras-related protein Rab-23 | / | 0.504 | |
| 2bme | GNP | Ras-related protein Rab-4A | / | 0.503 | |
| 4dlx | GNP | GTPase HRas | / | 0.502 | |
| 4hdo | GNP | Ras-related protein Rap-1b | / | 0.502 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.500 | |
| 2msd | GNP | MHC class I alpha chain | / | 0.499 | |
| 3cph | GDP | Ras-related protein SEC4 | / | 0.499 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.497 | |
| 1am4 | GNP | Cell division control protein 42 homolog | / | 0.496 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.495 | |
| 3rs7 | GNP | GTPase HRas | / | 0.495 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.495 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.495 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.492 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.492 | |
| 3pcr | GTP | ADP-ribosylation factor 6 | / | 0.492 | |
| 4d0l | GSP | Ras-related protein Rab-11A | / | 0.491 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.490 | |
| 1ky2 | GNP | GTP-binding protein YPT7 | / | 0.489 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.488 | |
| 1lev | CLI | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.488 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.488 | |
| 1rxh | BNI | Streptavidin | / | 0.487 | |
| 2rgc | GNP | GTPase HRas | / | 0.487 | |
| 4bwx | AGS | PAB-dependent poly(A)-specific ribonuclease subunit pan3 | / | 0.487 | |
| 4dso | GSP | GTPase KRas | / | 0.487 | |
| 3kuc | GDP | Ras-related protein Rap-1A | / | 0.486 | |
| 4itr | GDP | Cell division control protein 42 homolog | / | 0.486 | |
| 2ic5 | GNP | Ras-related C3 botulinum toxin substrate 3 | / | 0.485 | |
| 5hpy | GDP | Transforming protein RhoA | / | 0.485 | |
| 1m7b | GTP | Rho-related GTP-binding protein RhoE | / | 0.484 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.484 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.484 | |
| 3rsl | GNP | GTPase HRas | / | 0.484 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.483 | |
| 3moh | GDP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.483 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.482 | |
| 3ews | ADP | ATP-dependent RNA helicase DDX19B | 3.6.4.13 | 0.481 | |
| 4dlw | GNP | GTPase HRas | / | 0.480 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.479 | |
| 2qf2 | GDP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.479 | |
| 3law | GNP | Ras-related protein Rab-7a | / | 0.479 | |
| 3c14 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.478 | |
| 5iqh | GNP | Bifunctional AAC/APH | 2.3.1 | 0.478 | |
| 3ums | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.477 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.477 | |
| 1equ | EQI | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.476 | |
| 2wu5 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.476 | |
| 2wu5 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.476 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.475 | |
| 4dls | GNP | GTPase HRas | / | 0.475 | |
| 4l9w | GNP | GTPase HRas | / | 0.475 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.474 | |
| 2rc6 | NAP | Ferredoxin--NADP reductase | / | 0.474 | |
| 3x2w | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.474 | |
| 1a2b | GSP | Transforming protein RhoA | / | 0.472 | |
| 3kud | GDP | GTPase HRas | / | 0.472 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.472 | |
| 4o2l | GTP | GTP-binding protein Rheb | / | 0.472 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.472 | |
| 5iqd | GNP | Bifunctional AAC/APH | 2.3.1 | 0.472 | |
| 1e0j | ANP | DNA primase/helicase | 2.7.7 | 0.471 | |
| 2fju | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.471 | |
| 4dlv | GNP | GTPase HRas | / | 0.471 | |
| 5di3 | GNP | ADP-ribosylation factor-like protein 3 | / | 0.471 | |
| 1d5c | GDP | GTPase (Rab6) | / | 0.470 | |
| 2bgi | FAD | NADPH:ferredoxin reductase | / | 0.470 | |
| 2gvd | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.470 | |
| 3d45 | GDP | Poly(A)-specific ribonuclease PARN | 3.1.13.4 | 0.470 | |
| 4cid | ANP | EH domain-containing protein 2 | / | 0.470 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.470 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.469 | |
| 2gu8 | 796 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.468 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.468 | |
| 4fk8 | FAD | Ferredoxin--NADP reductase | / | 0.468 | |
| 5iot | UMP | Flavin-dependent thymidylate synthase | 2.1.1.148 | 0.468 | |
| 1s1c | GNP | Transforming protein RhoA | / | 0.467 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.467 | |
| 2yfe | YFE | Peroxisome proliferator-activated receptor gamma | / | 0.467 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.467 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.465 | |
| 3rs0 | GNP | GTPase HRas | / | 0.465 | |
| 3tfq | 07M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.465 | |
| 4px9 | ADP | ATP-dependent RNA helicase DDX3X | 3.6.4.13 | 0.465 | |
| 1cul | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.464 | |
| 1v8k | ANP | Kinesin-like protein KIF2C | / | 0.463 | |
| 3agl | A03 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.463 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.463 | |
| 2b35 | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
| 2wp9 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.462 | |
| 2wp9 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.462 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.462 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.461 | |
| 2iut | AGS | DNA translocase FtsK | / | 0.461 | |
| 3r7v | Z02 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.461 | |
| 4iac | ACP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.461 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.461 | |
| 1dq8 | COA | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.460 | |
| 1fnn | ADP | ORC1-type DNA replication protein | / | 0.460 | |
| 1svg | I04 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.460 | |
| 2g8a | UMP | Thymidylate synthase | / | 0.460 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.460 | |
| 2w2x | GSP | Ras-related C3 botulinum toxin substrate 2 | / | 0.460 | |
| 2zet | GTP | Ras-related protein Rab-27B | / | 0.460 | |
| 4ubu | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.460 | |
| 5iqg | GDP | Bifunctional AAC/APH | 2.3.1 | 0.460 | |
| 1kvo | OAP | Phospholipase A2, membrane associated | / | 0.459 | |
| 1svw | GTP | Probable GTP-binding protein EngB | / | 0.459 | |
| 2vnj | FAD | NADPH:ferredoxin reductase | / | 0.459 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 1knu | YPA | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
| 3n0c | FAD | Flavin-dependent thymidylate synthase | 2.1.1.148 | 0.458 | |
| 3r8u | Z31 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 3tif | ADP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.458 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.458 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.457 | |
| 1kzu | RG1 | Light-harvesting protein B-800/850 alpha chain | / | 0.457 | |
| 1kzu | RG1 | Light-harvesting protein B-800/850 beta chain | / | 0.457 | |
| 1nyx | DRF | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.457 | |
| 2v1x | ADP | ATP-dependent DNA helicase Q1 | 3.6.4.12 | 0.457 | |
| 2vnk | FAD | NADPH:ferredoxin reductase | / | 0.457 | |
| 2vo4 | GTB | 2,4-D inducible glutathione S-transferase | / | 0.457 | |
| 4axa | RKD | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.457 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.457 | |
| 2a1u | FAD | Electron transfer flavoprotein subunit alpha, mitochondrial | / | 0.456 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.456 | |
| 3q71 | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.456 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 4i3v | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.456 | |
| 5ab6 | CAA | Nonspecific lipid-transfer protein, putative | / | 0.456 | |
| 1a4r | GNH | Cell division control protein 42 homolog | / | 0.455 | |
| 1ibr | GNP | GTP-binding nuclear protein Ran | / | 0.455 | |
| 2l0x | GDP | GTP-binding protein Rheb | / | 0.455 | |
| 2ogi | GDP | Uncharacterized protein | / | 0.455 | |
| 3fgo | CZA | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.455 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.455 | |
| 3qx2 | X63 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 4jky | ADP | Adenylate kinase | / | 0.455 | |
| 1wdt | GTP | Elongation factor G (EF-G-2) | / | 0.454 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.454 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.454 | |
| 3v2b | AR6 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.454 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.454 | |
| 4goj | GNP | ADP-ribosylation factor-like protein 3 | / | 0.454 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.454 | |
| 4y0v | GDP | ADP-ribosylation factor 1, putative | / | 0.454 | |
| 5ftc | ADP | TPR domain protein | / | 0.454 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.453 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.453 | |
| 2bgj | FAD | NADPH:ferredoxin reductase | / | 0.453 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.453 | |
| 3vqx | BLK | Pyrrolysine--tRNA ligase | / | 0.453 | |
| 1efv | FAD | Electron transfer flavoprotein subunit alpha, mitochondrial | / | 0.452 | |
| 2bxm | IMN | Serum albumin | / | 0.452 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 2q4w | FAD | Cytokinin dehydrogenase 7 | 1.5.99.12 | 0.452 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.452 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.452 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.452 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.452 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.451 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.451 | |
| 2r3y | VAL_TYR_TRP_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.451 | |
| 2uw5 | GVN | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 3qqs | 17C | Anthranilate phosphoribosyltransferase | / | 0.451 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.451 | |
| 4p2l | FAD | Sulfhydryl oxidase 1 | 1.8.3.2 | 0.451 | |
| 5cb3 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.451 | |
| 1gil | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.450 | |
| 1z6l | FAD | Polyamine oxidase FMS1 | / | 0.450 | |
| 2dbz | NAP | Glyoxylate reductase | 1.1.1.26 | 0.450 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.450 | |
| 2gzl | 2AA | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.450 | |
| 2uw0 | GVK | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 2y65 | ADP | Kinesin heavy chain | / | 0.450 | |
| 2yyl | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.450 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.450 | |
| 3m6i | NAD | L-arabinitol 4-dehydrogenase | 1.1.1.12 | 0.450 | |
| 3r9n | Z68 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3uoy | NAP | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.450 | |
| 4pao | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.450 | |
| 4x2d | ATP | Fic family protein putative filamentation induced by cAMP protein | / | 0.450 | |
| 1bwf | ATF | Glycerol kinase | / | 0.449 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.449 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2gsd | NAD | Formate dehydrogenase | / | 0.449 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.449 | |
| 2qdx | FAD | Ferredoxin--NADP+ reductase | / | 0.449 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.449 | |
| 3eku | CY9 | Actin-5C | / | 0.449 | |
| 4c77 | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.449 | |
| 4iaf | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.449 | |
| 4mit | GTP | Rho-related protein racC | / | 0.449 | |
| 4oag | ADP | Mitochondrial dynamics protein MID51 | / | 0.449 | |
| 4pan | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.449 | |
| 4xw4 | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 5djt | FMN | NPH1-2 | / | 0.449 | |
| 1lqa | NDP | Protein tas | / | 0.448 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.448 | |
| 2hck | QUE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.448 | |
| 2oo7 | AP5 | Adenylate kinase | / | 0.448 | |
| 2xvv | 9DN | Serum albumin | / | 0.448 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.448 | |
| 3ez2 | ADP | Plasmid partition protein A | / | 0.448 | |
| 3u8d | U8D | Phospholipase A2, membrane associated | / | 0.448 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 4h6p | FMN | Chromate reductase | / | 0.448 | |
| 4hvi | 19S | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.448 | |
| 4i4b | 1CV | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.448 | |
| 4iak | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 4n9w | GDP | Phosphatidyl-myo-inositol mannosyltransferase | 2.4.1.57 | 0.448 | |
| 4v02 | ATP | Site-determining protein | / | 0.448 | |
| 4xey | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.448 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.447 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 2uze | C95 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 3crz | FAD | Ferredoxin--NADP+ reductase | / | 0.447 | |
| 3qd0 | 3Q4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 3wyf | GTP | GTP-binding nuclear protein | / | 0.447 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4apu | A2K | Progesterone receptor | / | 0.447 | |
| 4ho8 | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.447 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.447 | |
| 1rej | B1L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2gn8 | NAP | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.446 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.446 | |
| 3ii4 | 3II | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.446 | |
| 3rm7 | 19Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.446 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.446 | |
| 4hdh | ATP | Genome polyprotein | 2.7.7.48 | 0.446 | |
| 4kd1 | 1QK | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.446 | |
| 4wq5 | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.446 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.446 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1wli | FMN | FMN-binding protein | / | 0.445 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.445 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.445 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.445 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.445 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.445 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.445 | |
| 3gbk | 2PQ | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.445 | |
| 3n0b | FAD | Flavin-dependent thymidylate synthase | 2.1.1.148 | 0.445 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 3wnz | ADP | Alanine--anticapsin ligase | / | 0.445 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.445 | |
| 4eh9 | 0OQ | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 4hpt | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 4iwy | ADP | Ribosomal protein S6--L-glutamate ligase | / | 0.445 | |
| 4ork | GDP | Bifunctional AAC/APH | 2.3.1 | 0.445 | |
| 1ht8 | 34C | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.444 | |
| 1qm5 | PLP | Maltodextrin phosphorylase | 2.4.1.1 | 0.444 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.444 | |
| 1wn3 | HXC | Phenylacetic acid degradation protein PaaI | / | 0.444 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.444 | |
| 2b03 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.444 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.444 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.444 | |
| 3di6 | PDZ | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 3qe0 | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.444 | |
| 3qgd | 26S | Genome polyprotein | 2.7.7.48 | 0.444 | |
| 3qs8 | 17D | Anthranilate phosphoribosyltransferase | / | 0.444 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.444 | |
| 4jdc | NAD | Probable pyrroline-5-carboxylate dehydrogenase RocA | / | 0.444 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.444 | |
| 4ovi | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.444 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.444 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1g16 | GDP | Ras-related protein SEC4 | / | 0.443 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.443 | |
| 1osv | CHC | Bile acid receptor | / | 0.443 | |
| 1s1v | TNK | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 2igy | A2T | Plasmepsin 2 | / | 0.443 | |
| 2j0v | GDP | Rac-like GTP-binding protein ARAC7 | / | 0.443 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.443 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 3dat | MTX | Dihydrofolate reductase | / | 0.443 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.443 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 4c6u | TLG | 3-oxoacyl-ACP synthase | / | 0.443 | |
| 4iaz | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 5iqb | GNP | Bifunctional AAC/APH | 2.3.1 | 0.443 | |
| 1cs4 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.442 | |
| 1gwn | GTP | Rho-related GTP-binding protein RhoE | / | 0.442 | |
| 1ie3 | NAD | Malate dehydrogenase | / | 0.442 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.442 | |
| 2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.442 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.442 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.442 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.442 | |
| 3sbe | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.442 | |
| 3tnf | GNP | Ras-related protein Rab-8A | / | 0.442 | |
| 4e5k | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.442 | |
| 4fki | 09K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4ma6 | 28E | Ara h 8 allergen | / | 0.442 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.442 | |
| 4o0w | ADN | Aurora kinase A | 2.7.11.1 | 0.442 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.442 | |
| 4xr9 | TMP | CalS8 | / | 0.442 | |
| 5eso | ISC | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.442 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.442 | |
| 5iqe | GNP | Bifunctional AAC/APH | 2.3.1 | 0.442 | |
| 4k5y | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.442 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.441 | |
| 2clp | NDP | Aflatoxin B1 aldehyde reductase member 3 | / | 0.441 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.441 | |
| 2wdq | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.441 | |
| 2wdq | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.441 | |
| 2xjj | L81 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 4bew | CZA | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.441 | |
| 4f9w | LM4 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 4ijr | NDP | D-arabinose dehydrogenase [NAD(P)+] heavy chain | 1.1.1.117 | 0.441 | |
| 4l98 | LRG | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 4r43 | GDP | Phosphoenolpyruvate carboxykinase [GTP] | / | 0.441 | |
| 5byl | GCP | Bifunctional AAC/APH | 2.3.1 | 0.441 | |
| 1db5 | 6IN | Phospholipase A2, membrane associated | / | 0.440 | |
| 1e8h | ADP | Vanillyl-alcohol oxidase | 1.1.3.38 | 0.440 | |
| 1ne6 | SP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.440 | |
| 1qmz | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.440 | |
| 1z0d | GDP | Ras-related protein Rab-5C | / | 0.440 | |
| 2dbr | NAP | Glyoxylate reductase | 1.1.1.26 | 0.440 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.440 | |
| 2jfg | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.440 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.440 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.440 | |
| 2v7q | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.440 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 3cvy | FAD | RE11660p | / | 0.440 | |
| 3dmh | SAM | Probable ribosomal RNA small subunit methyltransferase | / | 0.440 | |
| 3fvq | ATP | Fe(3+) ions import ATP-binding protein FbpC | / | 0.440 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.440 | |
| 3pju | C2E | Diguanylate cyclase/phosphodiesterase | / | 0.440 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.440 | |
| 3uic | 09T | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 4b1f | KRH | Glutamate racemase | / | 0.440 | |
| 4b1i | A8P | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.440 | |
| 4cf7 | ADP | Adenylate kinase | / | 0.440 | |
| 4dh5 | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 4rhe | FMN | Flavin prenyltransferase UbiX | / | 0.440 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.440 | |
| 4weq | NAP | NAD-dependent dehydrogenase | / | 0.440 | |
| 5f0a | 1FB | cGMP-dependent protein kinase, putative | / | 0.440 |