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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3k30ADPHistamine dehydrogenase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3k30ADPHistamine dehydrogenase/1.000
1zmcNADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.455
4b69FADL-ornithine N(5)-monooxygenase/0.449
4tm0FADKtzI/0.445
4b66FADL-ornithine N(5)-monooxygenase/0.441
4bk3FADProbable salicylate monooxygenase/0.440